Projects per year
Personal profile
Biography
Mastura Monif (BBiomed Sci, B Sci Hons, MBBS, PhD, FRACP) is a senior research fellow in the Van Cleef Centre for Nervous Diseases, Department of Neuroscience, within the Central Clinical School. She leads the Neuroimmunology, Neuroinflammation and Neurological Diseases Lab at Monash University Department of Neuroscience. Her research interests are to understand how neuroinflammation can induce neurological disease. The main areas of research focus in her lab are: Autoimmune Encephalitis, Glioblastoma (brain cancer), Autoimmune Epilepsy, and Multiple Sclerosis.
Research interests
To understand how neuroinflammation and innate immune responses can lead to neurological diseases.
To decipher biomarkers of neuroinflammatory disease that can assist with disease diagnosis, prognostication and aid in improved therapeutics.
Clinical activities
She is also a Consultant Neurologist at Alfred Health and Royal Melbourne Hospital. She leads the Neuroimmunology Service at Alfred Health. Her clinical interest and expertise are neuroimmunological diseases such as Multiple Sclerosis, Autoimmune Encephalitis, and other central nervous system inflammatory and autoimmune disorders. She also oversees the neurology division of CAR-T (Chimeric Antigen Receptor T cell) Therapy for haematological malignancies at Alfred Health focusing on diagnosis and management of neurological complications of CAR-T Therapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Neuroimmunology, Fellowship, Royal Melbourne Hospital
Award Date: 30 Dec 2017
Neurology, Neurology Specialist Qualification - FRACP, Royal Australasian College of Physicians (RACP)
Award Date: 20 Oct 2017
Physician Training, Fellow of the Australian College of Physicians, Royal Australasian College of Physicians (RACP)
Award Date: 29 Jul 2014
Bachelor of Medicine, Bachelor of Surgery, Bachelor of Medicine, Bachelor of Surgery, University of Melbourne
Award Date: 4 Dec 2010
Neuroscience, Neuroimmunology, PhD, University of Melbourne
Award Date: 4 Dec 2010
Neuroscience, Bachelor of Science Honours, University of Melbourne
Award Date: 4 Dec 2004
External positions
Head of Neuroimmunology Service , Alfred Hospital
20 Jun 2021 → …
Research area keywords
- neurology
- neuroimmunology
- neuroinflammation
- Multiple Sclerosis (MS)
- Autoimmune Encephalitis
- Gliomas
- Microglia / monocytes
- Purinergic receptors
- P2X7R
Network
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A randomized, double-blind, placebo- controlled, multicenter, Phase 3, PIVOTAL study with an open-label Extension period to evaluate the efficacy and safety of rozanolixizumab in adult participants with Myelin oligodendrocyte glycoprotein (MOG) ANTIBODY-ASSOCIATED disease (MOG-AD).
13/05/22 → 31/12/26
Project: Research
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Glioblastoma - inhibition of P2X7R as a potential therapeutic target for treatment of this aggressive cancer.
Monif, M., Hunn, M., Drummond, K. J., McLean, C., Jones, N., Sanfilippo, P. & O'Brien, T.
1/01/22 → 31/12/25
Project: Research
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Autoimmune Encephalitis - a rare and debilitating neurological illness affecting the Australian population. A study of the Australian Autoimmune Encephalitis Consortium.
Monif, M., Butzkueven, H., Reddel, S. W., Kalincik, T., Tarlinton, D., Seneviratne, U., Kulkarni, J., Buzzard, K. & Taylor, B. V. M.
1/06/20 → 31/05/25
Project: Research
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Neuroimaging characteristics may aid in diagnosis, subtyping, and prognosis in autoimmune encephalitis
Broadley, J., Wesselingh, R., Beech, P., Seneviratne, U., Kyndt, C., Buzzard, K., Nesbitt, C., D’Souza, W., Brodtmann, A., Macdonell, R., Kalincik, T., O’Brien, T. J., Butzkueven, H., Monif, M. & on behalf of the Australian Autoimmune Encephalitis Consortium, Apr 2023, In: Neurological Sciences. 44, 4, p. 1327–1340 14 p.Research output: Contribution to journal › Article › Research › peer-review
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Peripheral monocytes and soluble biomarkers in autoimmune encephalitis
Wesselingh, R., Griffith, S., Broadley, J., Tarlinton, D., Buzzard, K., Seneviratne, U., Butzkueven, H., O'Brien, T. J. & Monif, M., Feb 2023, In: Journal of Autoimmunity. 135, 10 p., 103000.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Prediction of relapse activity when switching to cladribine for multiple sclerosis
Zhong, M., van der Walt, A., Monif, M., Hodgkinson, S., Eichau, S., Kalincik, T., Lechner-Scott, J., Buzzard, K., Skibina, O., Van Pesch, V., Butler, E., Prevost, J., Girard, M., Oh, J., Butzkueven, H., Jokubaitis, V. & on behalf of the MSBase Study Group, Jan 2023, In: Multiple Sclerosis Journal. 29, 1, p. 119-129 11 p.Research output: Contribution to journal › Article › Research › peer-review
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Autoimmune Encephalitis in Long-Standing Schizophrenia: A Case Report
Vaux, A., Robinson, K., Saglam, B., Cheuk, N., Kilpatrick, T., Evans, A. & Monif, M., 11 Feb 2022, In: Frontiers in Neurology. 12, 7 p., 810926.Research output: Contribution to journal › Article › Other › peer-review
Open Access1 Citation (Scopus) -
Comparing switch to ocrelizumab, cladribine or natalizumab after fingolimod treatment cessation in multiple sclerosis
Zhu, C., Zhou, Z., Roos, I., Merlo, D., Kalincik, T., Ozakbas, S., Skibina, O., Kuhle, J., Hodgkinson, S., Boz, C., Alroughani, R., Lechner-Scott, J., Barnett, M., Izquierdo, G., Prat, A., Horakova, D., Kubala Havrdova, E., Macdonell, R., Patti, F., Khoury, S. J., & 10 others , Dec 2022, In: Journal of Neurology, Neurosurgery and Psychiatry. 93, 12, p. 1330-1337 8 p.Research output: Contribution to journal › Article › Research › peer-review
Prizes
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2019 Monash Graduate Supervisor of the year
Monif, Mastura (Recipient), 19 Dec 2019
Prize: Prize (including medals and awards)
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Brain Foundation Research Award
Monif, Mastura (Recipient), 2018
Prize: Prize (including medals and awards)
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Charles and Sylvia Viertel Clinical Investigator Award
Monif, Mastura (Recipient), 6 Nov 2019
Prize: Prize (including medals and awards)
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Neurosciences Foundation Haynes Fellowship
Monif, Mastura (Recipient), 2017
Prize: Competitive Fellowships
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Royal Australian College of Physicians Trainee Research Award in Victoria
Monif, Mastura (Recipient), 2017
Prize: Prize (including medals and awards)
Press/Media
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Neuroscience researchers support Brain Cancer Awareness month
27/05/22
1 Media contribution
Press/Media: Public Engagement Activities
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Zeroing in on improved brain cancer diagnosis and treatment: Rare Disease Day feature
28/02/22
1 Media contribution
Press/Media: Article/Feature
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News article story on Autoimmune Encephalitis
24/11/21
1 Media contribution
Press/Media: Profile/Interview