Projects per year
Personal profile
Biography
Position
Professor of Medicinal Chemistry
Director ARC Centre for Fragment-Based Design
Scientific Director Monash Fragment-Based Drug Design Platform
Medicinal Chemistry
Monash Institute of Pharmaceutical Sciences
Research interests
Fragment-based drug design
NMR Spectroscopy
Structure-based design of novel anti-microbial agents
Analysis of protein-ligand interactions
Protein structure determination and structural biology
Monash teaching commitment
- Spectrometric identification of small molecules
- Drug-protein interactions
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Fragment-Based Drug Design
- NMR spectroscopy
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Developing and optimising compounds targeting the flaviviral protease enzymes from Zika and Dengue
Scanlon, M. & Murray, J.
28/01/22 → 21/07/24
Project: Research
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IC18.12 Cytiva SPR method development for Fragment-Based Design
Scanlon, M., Norton, R. & O'Meara, T.
16/09/21 → 16/09/25
Project: Research
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IC18.13 VAST Fragment Based Discovery towards novel P2X4 inhibitors
Kassiou, M., Scanlon, M. & Mackay, J. P.
1/01/21 → 30/06/24
Project: Research
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IC18.5 Developing and optimising chemical elaboration (REFiL) of fragments into potent leads (Vernalis) for bacterial virulence enzyme DsbA
Scanlon, M. & Murray, J.
1/01/20 → 31/12/23
Project: Research
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IC18.4 Enabling fragment-based lead discovery for challenging targets
Mackay, J. P., Kassiou, M., Scanlon, M. & Capuano, B.
19/12/19 → 21/07/24
Project: Research
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Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores
Whitehouse, R. L., Alwan, W. S., Ilyichova, O. V., Taylor, A. J., Chandrashekaran, I. R., Mohanty, B., Doak, B. C. & Scanlon, M. J., 1 Jan 2023, In: RSC Medicinal Chemistry. 14, 1, p. 135-143 9 p.Research output: Contribution to journal › Article › Research › peer-review
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Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain
Adams, L. A., Wilkinson-White, L. E., Gunzburg, M. J., Headey, S. J., Mohanty, B., Scanlon, M. J., Capuano, B., Mackay, J. P. & Doak, B. C., 18 Apr 2023, In: Journal of Medicinal Chemistry. 66, 8, p. 5859–5872 14 p.Research output: Contribution to journal › Article › Research › peer-review
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Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA
Petit, G. A., Mohanty, B., McMahon, R. M., Nebl, S., Hilko, D. H., Wilde, K. L., Scanlon, M. J., Martin, J. L. & Halili, M. A., 1 Jan 2022, In: Acta Crystallographica Section D: Structural Biology. 78, p. 75-90 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes
Mohanty, B., Orts, J., Wang, G., Nebl, S., Alwan, W. S., Doak, B. C., Williams, M. L., Heras, B., Mobli, M. & Scanlon, M. J., Dec 2022, In: Scientific Reports. 12, 1, 10 p., 11231.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferase
Mullally, C., Stubbs, K. A., Thai, V. C., Anandan, A., Bartley, S., Scanlon, M. J., Jarvis, G. A., John, C. M., Lim, K. Y. L., Sullivan, C. M., Sarkar-Tyson, M., Vrielink, A. & Kahler, C. M., 25 Aug 2022, In: Journal of Antimicrobial Chemotherapy. 77, 9, p. 2441-2447 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)
Activities
- 1 Submissions to industry or govt committees, commissions and inquiries
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Medicinal Chemistry
Martin Scanlon (Member)
2 Sept 2013Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries
Equipment
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Monash Fragment Platform
Bradley Doak (Manager) & Martin Scanlon (Manager)
Faculty of Pharmacy and Pharmaceutical SciencesFacility/equipment: Facility