Projects per year
Personal profile
Biography
Position
Professor of Medicinal Chemistry
Director ARC Centre for Fragment-Based Design
Scientific Director Monash Fragment-Based Drug Design Platform
Medicinal Chemistry
Monash Institute of Pharmaceutical Sciences
Research interests
Fragment-based drug design
NMR Spectroscopy
Structure-based design of novel anti-microbial agents
Analysis of protein-ligand interactions
Protein structure determination and structural biology
Monash teaching commitment
- Spectrometric identification of small molecules
- Drug-protein interactions
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Fragment-Based Drug Design
- NMR spectroscopy
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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How lipid binding proteins shape the activity of nuclear hormone receptors
Halls, M. (Primary Chief Investigator (PCI)) & Scanlon, M. (Chief Investigator (CI))
Australian Research Council (ARC)
31/12/24 → 30/12/27
Project: Research
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IC18.12 Cytiva SPR method development for Fragment-Based Design
Scanlon, M. (Primary Chief Investigator (PCI)), Norton, R. (Chief Investigator (CI)) & O'Meara, T. (Partner Investigator (PI))
16/09/21 → 16/09/25
Project: Research
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Melbourne Biomolecular NMR Network
Stone, M. (Primary Chief Investigator (PCI)), Bottomley, S. (Chief Investigator (CI)), Gooley, P. R. (Chief Investigator (CI)), Langford, S. (Chief Investigator (CI)), Reynolds, E. C. (Chief Investigator (CI)), Scammells, P. (Chief Investigator (CI)), Scanlon, M. (Chief Investigator (CI)), Separovic, F. (Chief Investigator (CI)), Tuck, K. (Chief Investigator (CI)), Whisstock, J. (Chief Investigator (CI)) & Wilce, J. (Chief Investigator (CI))
Australian Research Council (ARC), University of Melbourne, Monash University
1/01/09 → …
Project: Research
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Developing PKCe-Degrading PROTACs as Dual-Action Agents to Treat Type 2 Diabetes
Schmitz-Peiffer, C. (Primary Chief Investigator (PCI)) & Scanlon, M. (Chief Investigator (CI))
Project: Research
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Structure-activity-relationship analysis of lead candidates to provide insight into how the structural components of our lead candidates influence pharmacokinetics
Scanlon, M. (Supervisor) & Konstantinidou, E. (Primary Chief Investigator (PCI))
15/06/23 → 19/12/23
Project: Research
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Multiplexed Native Mass Spectrometry Determination of Ligand Selectivity for Fatty Acid-Binding Proteins
Phan, M. Q., Chandrashekaran, I. R., Akhtar, N., Konstantinidou, E., Devine, S. M., Doak, B. C., Nebl, T., Creek, D. J., Scanlon, M. J. & Norton, R. S., 11 Jul 2024, In: ACS Medicinal Chemistry Letters. 15, 7, p. 1071–1079 9 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores
Whitehouse, R. L., Alwan, W. S., Ilyichova, O. V., Taylor, A. J., Chandrashekaran, I. R., Mohanty, B., Doak, B. C. & Scanlon, M. J., 1 Jan 2023, In: RSC Medicinal Chemistry. 14, 1, p. 135-143 9 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain
Adams, L. A., Wilkinson-White, L. E., Gunzburg, M. J., Headey, S. J., Mohanty, B., Scanlon, M. J., Capuano, B., Mackay, J. P. & Doak, B. C., 18 Apr 2023, In: Journal of Medicinal Chemistry. 66, 8, p. 5859–5872 14 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA
Petit, G. A., Mohanty, B., McMahon, R. M., Nebl, S., Hilko, D. H., Wilde, K. L., Scanlon, M. J., Martin, J. L. & Halili, M. A., 1 Jan 2022, In: Acta Crystallographica Section D: Structural Biology. 78, p. 75-90 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes
Mohanty, B., Orts, J., Wang, G., Nebl, S., Alwan, W. S., Doak, B. C., Williams, M. L., Heras, B., Mobli, M. & Scanlon, M. J., Dec 2022, In: Scientific Reports. 12, 1, 10 p., 11231.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)
Activities
- 1 Submissions to industry or govt committees, commissions and inquiries
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Medicinal Chemistry
Scanlon, M. (Member)
2 Sept 2013Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries
Equipment
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Monash Fragment Platform (MFP)
Doak, B. (Manager) & Scanlon, M. (Manager)
Faculty of Pharmacy and Pharmaceutical SciencesFacility/equipment: Facility