• Innovation Walk, 19

    3168 Melbourne



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Personal profile



Dr Martin Davey gained his PhD (2013) in the group of Prof. Bernhard Moser and Dr Matthias Eberl at Cardiff University, exploring the responses of human γδ T cells towards multi-drug resistant bacterial pathogens, in concert with monocytes and neutrophils. He then undertook postdoctoral research training in the group of Prof. Ben Willcox at the University of Birmingham, UK. There he employed T cell receptor (TCR) deep sequencing and single cell methodology to explore the underlying biology of this enigmatic T cell population, revealing an alternative immunobiology that governs a large population of human γδ T cells. He joined Monash University’s Biomedicine Discovery Institute in June 2018 and has established the immune surveillance laboratory to explore the role of γδ T cells in microbial infections and tissue immune surveillance.

Research interests

We investigate the role of an “unconventional” group of human immune cells in their ability to protect human body throughout life. The human immune system is a highly specialised network of cells, organs, receptors and soluble factors that protects the host from infection and cancer, while promoting normal function of the tissues in concert with the microbiome. The immune system uses lymphocytes to generate immunological memory responses to numerous challenges throughout life. Three lineages of lymphocytes have co-evolved over the last 550 million years: B cells, ɑβ T cells and γδ T cells. While conventional ɑβ T cells and B cells have been the subject of significant scientific research, leading to life changing breakthroughs in vaccination and cancer treatment, our group studies poorly understood subsets of unconventional T cells: γδ T cells and mucosal associated invariant T (MAIT) cells.

We use cutting-edge approaches, supported by Monash Platform Technologies, that includes the application of multi parameter flow cytometry and next generation sequencing (RNA-seq and TCR-seq) to human patient samples after exposure to pathogens of global importance (Malaria, tuberculosis and cytomegalovirus) and human tissue samples.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research area keywords

  • T cell receptors
  • gamma delta T cells
  • Human Immunology
  • Viral immunity
  • Malaria
  • Tuberculosis
  • immune memory


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