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Research Output

2020

Metastatic melanoma presenting as intravenous tumourthrombus

Nguyen, J., Clements, W., McLean, C., Haydon, A., Moore, M., Yap, K. SK., Mar, V. & Shackleton, M., 7 Feb 2020, (Accepted/In press) In : Journal of Medical Imaging and Radiation Oncology. 3 p.

Research output: Contribution to journalArticleOtherpeer-review

2019

Incidence, features and management of radionecrosis in melanoma patients treated with cerebral radiotherapy and anti-PD-1 antibodies

Pires da Silva, I., Glitza, I. C., Haydu, L. E., Johnpulle, R., Banks, P. D., Grass, G. D., Goldinger, S. M. A., Smith, J. L., Everett, A. S., Koelblinger, P., Roberts-Thomson, R., Millward, M., Atkinson, V. G., Guminski, A., Kapoor, R., Conry, R. M., Carlino, M. S., Wang, W., Shackleton, M. J., Eroglu, Z. & 5 others, Lo, S., Hong, A. M., Long, G. V., Johnson, D. B. & Menzies, A. M., 1 Jul 2019, In : Pigment Cell and Melanoma Research. 32, p. 553-563 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Personalised surveillance after treatment for high-risk cancer

Guo, C., Lewin, J. & Shackleton, M., 1 Jan 2019, In : Oncotarget. 10, 7, p. 694-695 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
1 Citation (Scopus)

Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA

Tan, L., Sandhu, S., Lee, R. J., Li, J., Callahan, J., Ftouni, S., Dhomen, N., Middlehurst, P., Wallace, A., Raleigh, J., Hatzimihalis, A., Henderson, M. A., Shackleton, M., Haydon, A., Mar, V., Gyorki, D. E., Oudit, D., Dawson, M. A., Hicks, R. J., Lorigan, P. & 4 others, McArthur, G. A., Marais, R., Wong, S. Q. & Dawson, S. J., 1 May 2019, In : Annals of Oncology. 30, 5, p. 804-814 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Somatic hypermutation of the YAP oncogene in a human cutaneous melanoma

Zhang, X., Tang, J. Z., Vergara, I. A., Zhang, Y., Szeto, P., Yang, L., Mintoff, C., Colebatch, A., McIntosh, L., Mitchell, K. A., Shaw, E., Rizos, H., Long, G. V., Hayward, N., McArthur, G. A., Papenfuss, A. T., Harvey, K. F. & Shackleton, M., 1 Jul 2019, In : Molecular Cancer Research. 17, 7, p. 1435-1449 15 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
2018

Rheumatic immune-related adverse events secondary to anti–programmed death-1 antibodies and preliminary analysis on the impact of corticosteroids on anti-tumour response: A case series

Mitchell, E. L., Lau, P. K. H., Khoo, C., Liew, D., Leung, J., Liu, B., Rischin, A., Frauman, A. G., Kee, D., Smith, K., Brady, B., Rischin, D., Gibson, A., Mileshkin, L., Klein, O., Weickhardt, A., Arulananda, S., Shackleton, M., McArthur, G., Östör, A. & 7 others, Cebon, J., Solomon, B., Buchanan, R. RC., Wicks, I. P., Lo, S., Hicks, R. J. & Sandhu, S., 1 Dec 2018, In : European Journal of Cancer. 105, p. 88-102 15 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Surveillance imaging with FDG-PET/CT in the post-operative follow-up of stage 3 melanoma

Lewin, J., Sayers, L., Kee, D., Walpole, I., Sanelli, A., Te Marvelde, L., Herschtal, A., Spillane, J., Gyorki, D., Speakman, D., Estall, V., Donahoe, S., Pohl, M., Pope, K., Chua, M., Sandhu, S., McArthur, G. A., McCormack, C. J., Henderson, M., Hicks, R. J. & 1 others, Shackleton, M., 1 Jul 2018, In : Annals of Oncology. 29, 7, p. 1569-1574 6 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
2017

Calcium-dependent enhancement by extracellular acidity of the cytotoxicity of mitochondrial inhibitors against melanoma

Noguchi, F., Inui, S., Fedele, C., Shackleton, M. & Itami, S., 1 May 2017, In : Molecular Cancer Therapeutics. 16, 5, p. 936-947 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Patient-derived xenografting of human melanoma

Boyle, S. E., Fedele, C. G. & Shackleton, M., 2017, Patient Derived Tumor Xenograft Models: Promise, Potential and Practice. Uthamanthil, R., Tinkey, P. & de Stanchina, E. (eds.). Elsevier, p. 341-363 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Whole-genome landscapes of major melanoma subtypes

Hayward, N. K., Wilmott, J. S., Waddell, N., Johansson, P. A., Field, M. A., Nones, K., Patch, A. M., Kakavand, H., Alexandrov, L. B., Burke, H., Jakrot, V., Kazakoff, S., Holmes, O., Leonard, C., Sabarinathan, R., Mularoni, L., Wood, S., Xu, Q., Waddell, N., Tembe, V. & 29 others, Pupo, G. M., De Paoli-Iseppi, R., Vilain, R. E., Shang, P., Lau, L. M. S., Dagg, R. A., Schramm, S. J., Pritchard, A., Dutton-Regester, K., Newell, F., Fitzgerald, A., Shang, C. A., Grimmond, S. M., Pickett, H. A., Yang, J. Y., Stretch, J. R., Behren, A., Kefford, R. F., Hersey, P., Long, G. V., Cebon, J., Shackleton, M., Spillane, A. J., Saw, R. P. M., López-Bigas, N., Pearson, J. V., Thompson, J. F., Scolyer, R. A. & Mann, G. J., 11 May 2017, In : Nature. 545, 7653, p. 175-180 6 p.

Research output: Contribution to journalArticleResearchpeer-review

318 Citations (Scopus)
2016

A community-based model of rapid autopsy in end-stage cancer patients

Alsop, K., Thorne, H., Sandhu, S., Hamilton, A., Mintoff, C., Christie, E., Spruyt, O., Williams, S., McNally, O., Mileshkin, L., Ananda, S., Hallo, J., Loi, S., Scott, C., Savas, P., Devereux, L., O'Brien, P., Gunawardena, S., Hampson, C., Strachan, K. & 44 others, Jaravaza, R. D., Francis, V., Young, G., Ranson, D., Samaranayake, R., Stevens, D., Boyle, S., Fedele, C., Topp, M., Ho, G., Teo, Z. L., Taylor, R. A., Papargiris, M. M., Lawrence, M. G., Wang, H., Risbridger, G. P., Haynes, N. M., Medon, M., Johnstone, R. W., Vidacs, E., Arnau, G. M., Vergara, I. A., Papenfuss, A. T., McArthur, G., Waring, P., Carvosso, S., Angel, C., Gyorki, D., Solomon, B., Mitchell, G., Shanley, S., Francis, P. A., Dawson, S. J., Haffenden, A., Tidball, E., Volchek, M., Pyman, J., Madadin, M., Leditschke, J., Cordner, S., The Melbourne Melanoma Project, Australian Ovarian Cancer Study Group (AOCS), Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer (kConFab) & Shackleton, M., 1 Oct 2016, In : Nature Biotechnology. 34, 10, p. 1010-1014 5 p.

Research output: Contribution to journalLetterResearchpeer-review

23 Citations (Scopus)

A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis

Ebert, L. M., Tan, L. Y., Johan, M. Z., Min, K. K. M., Cockshell, M. P., Parham, K. A., Betterman, K. L., Szeto, P., Boyle, S., Silva, L., Peng, A., Zhang, Y. F., Ruszkiewicz, A., Zannettino, A. C. W., Gronthos, S., Koblar, S., Harvey, N. L., Lopez, A. F., Shackleton, M. & Bonder, C. S., 1 Oct 2016, In : Angiogenesis. 19, 4, p. 463-486 24 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth

Dewaele, M., Tabaglio, T., Willekens, K., Bezzi, M., Teo, S. X., Low, D. H. P., Koh, C. M., Rambow, F., Fiers, M., Rogiers, A., Radaelli, E., Al-Haddawi, M., Tan, S. Y., Hermans, E., Amant, F., Yan, H., Lakshmanan, M., Koumar, R. C., Lim, S. T., Derheimer, F. A. & 7 others, Campbell, R. M., Bonday, Z., Tergaonkar, V., Shackleton, M., Blattner, C., Marine, J. C. & Guccione, E., 4 Jan 2016, In : Journal of Clinical Investigation. 126, 1, p. 68-84 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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60 Citations (Scopus)

CD271 expression on patient melanoma cells is unstable and unlinked to tumorigenicity

Boyle, S. E., Fedele, C. G., Corbin, V., Wybacz, E., Szeto, P., Lewin, J., Young, R. J., Wong, A., Fuller, R., Spillane, J., Speakman, D., Donahoe, S., Pohl, M., Gyorki, D., Henderson, M. A., Johnstone, R. W., Papenfuss, A. T. & Shackleton, M., 1 Jul 2016, In : Cancer Research. 76, 13, p. 3965-3977 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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15 Citations (Scopus)

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome

Tan, L. Y., Mintoff, C., Johan, M. Z., Ebert, B. W., Fedele, C., Zhang, Y. F., Szeto, P., Sheppard, K. E., McArthur, G. A., Foster-Smith, E., Ruszkiewicz, A., Brown, M. P., Bonder, C. S., Shackleton, M. & Ebert, L. M., 1 Jan 2016, In : Oncotarget. 7, 29, p. 46492-46508 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP

Paul, P. J., Raghu, D., Chan, A. L., Gulati, T., Lambeth, L. S., Takano, E., Herold, M. J., Hagekyriakou, J., Vessella, R. L., Fedele, C., Shackleton, M., Williams, E. D., Fox, S., Williams, S., Haupt, S., Gamell, C. & Haupt, Y., 1 Dec 2016, In : Oncogene. 35, 48, p. 6235-6245 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma

Eskiocak, U., Ramesh, V., Gill, J. G., Zhao, Z., Yuan, S. W., Wang, M., Vandergriff, T., Shackleton, M., Quintana, E., Johnson, T. M., Deberardinis, R. J. & Morrison, S. J., 22 Aug 2016, In : Nature Communications. 7, 18 p., 12336.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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18 Citations (Scopus)

The use of ipilimumab in patients with rheumatoid arthritis and metastatic melanoma

Lee, B., Wong, A., Kee, D., Neeson, P., Shackleton, M., McArthur, G. & Sandhu, S., 18 Jun 2016, In : Annals of Oncology. 27, 6, p. 1174-1177 4 p., mdw056.

Research output: Contribution to journalLetterOtherpeer-review

Open Access
24 Citations (Scopus)
2015

Corrigendum: Whole-genome characterization of chemoresistant ovarian cancer

Patch, A-M., Christie, E. L., Etemadmoghadam, D., Garsed, D. W., George, J., Fereday, S., Nones, K., Cowin, P., Alsop, K., Bailey, P. J., Kassahn, K. S., Newell, F., Quinn, M. C. J., Kazakoff, S., Quek, K., Wilhelm-Benartzi, C., Curry, E., Leong, H. S., Hamilton, A., Mileshkin, L. & 63 others, Au-Yeung, G. H., Kennedy, C., Hung, J., Chiew, Y. E., Harnett, P., Friedlander, M., Quinn, M. C. J., Pyman, J. M., Cordner, S., O'Brien, P., Leditschke, J., Young, G., Strachan, K., Waring, P., Azar, W. J., Mitchell, C., Traficante, N., Hendley, J., Thorne, H. J., Shackleton, M., Miller, D. K., Arnau, G. M., Tothill, R. W., Holloway, T. P., Semple, T., Harliwong, I., Nourse, C., Nourbakhsh, E., Manning, S., Idrisoglu, S., Bruxner, T. J. C., Christ, A. N., Poudel, B., Holmes, O., Anderson, M., Leonard, C., Lonie, A., Hall, N., Wood, S., Taylor, D. F., Xu, Q., Fink, J. L., Waddell, N., Drapkin, R., Stronach, E., Gabra, H., Brown, R., Jewell, A., Nagaraj, S. H., Markham, E., Wilson, P. J., Ellul, J., McNally, O. M., Doyle, M. A., Vedururu, R., Stewart, C., Lengyel, E., Pearson, J. V., Waddell, N., DeFazio, A., Grimmond, S., Bowtell, D. D. L. & The Australian Ovarian Cancer Study Group, 19 Nov 2015, In : Nature. 527, 7578, p. 398 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Long-term outcome in BRAFV600E melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression

Puzanov, I., Amaravadi, R. K., McArthur, G. A., Flaherty, K. T., Chapman, P. B., Sosman, J. A., Ribas, A., Shackleton, M., Hwu, P., Chmielowski, B., Nolop, K. B., Lin, P. S. & Kim, K. B., 1 Jan 2015, In : European Journal of Cancer. 51, 11, p. 1435-1443 9 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Post-operative survival following metastasectomy for patients receiving BRAF inhibitor therapy is associated with duration of pre-operative treatment and elective indication

He, M., Lovell, J., Ng, B. L., Spillane, J., Speakman, D., Henderson, M. A., Shackleton, M. & Gyorki, D. E., 1 Jun 2015, In : World Journal of Surgical Oncology. 111, 8, p. 980-984 5 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma

Ramsdale, R., Jorissen, R. N., Li, F. Z., Al-Obaidi, S., Ward, T., Sheppard, K. E., Bukczynska, P. E., Young, R. J., Boyle, S. E., Shackleton, M., Bollag, G., Long, G. V., Tulchinsky, E., Rizos, H., Pearson, R. B., McArthur, G. A., Dhillon, A. S. & Ferrao, P. T., 18 Aug 2015, In : Science Signaling. 8, 390, 13 p., ra82.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

Tumour procurement, DNA extraction, coverage analysis and optimisation of mutation-detection algorithms for human melanoma genomes

Wilmott, J. S., Field, M. A., Johansson, P. A., Kakavand, H., Shang, P., De Paoli-Iseppi, R., Vilain, R. E., Pupo, G. M., Tembe, V., Jakrot, V., Shang, C. A., Cebon, J., Shackleton, M., Fitzgerald, A., Thompson, J. F., Hayward, N. K., Mann, G. J. & Scolyer, R. A., 1 Dec 2015, In : Pathology. 47, 7, p. 683-693 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

UV-associated mutations underlie the etiology of MCV-negative Merkel cell carcinomas

Wong, S. Q., Waldeck, K., Vergara, I. A., Schröder, J., Madore, J., Wilmott, J. S., Colebatch, A. J., De Paoli-Iseppi, R., Li, J., Lupat, R., Semple, T., Arnau, G. M., Fellowes, A., Leonard, J. H., Hruby, G., Mann, G. J., Thompson, J. F., Cullinane, C., Johnston, M., Shackleton, M. & 10 others, Sandhu, S., Bowtell, D. D. L., Johnstone, R. W., Fox, S. B., McArthur, G. A., Papenfuss, A. T., Scolyer, R. A., Gill, A. J., Hicks, R. J. & Tothill, R. W., 15 Dec 2015, In : Cancer Research. 75, 24, p. 5228-5234 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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123 Citations (Scopus)

Whole-genome characterization of chemoresistant ovarian cancer

Patch, A-M., Christie, E., Etemadmoghadam, D., Garsed, D. W., George, J., Fereday, S., Nones, K., Cowin, P., Alsop, K., Bailey, P. J., Kassahn, K. S., Newell, F., Quinn, M. C. J., Kazakoff, S., Quek, K., Wilhelm-Benartzi, C., Curry, E., Leong, H. S., Hamilton, A., Mileshkin, L. & 62 others, Au-Yeung, G. H., Kennedy, C., Hung, J., Chiew, Y. E., Harnett, P., Friedlander, M., Quinn, M., Pyman, J. M., Cordner, S., O'Brien, P., Leditschke, J., Young, G., Strachan, K., Waring, P., Azar, W. J., Mitchell, C., Traficante, N., Hendley, J., Thorne, H. J., Shackleton, M., Miller, D. K., Arnau, G. M., Tothill, R. W., Holloway, T. P., Semple, T., Harliwong, I., Nourse, C., Nourbakhsh, E., Manning, S., Idrisoglu, S., Bruxner, T. J. C., Christ, A. N., Poudel, B., Holmes, O., Anderson, M., Leonard, C., Lonie, A., Hall, N., Wood, S., Taylor, D. F., Xu, Q., Lynn Fink, J., Waddell, N., Drapkin, R., Stronach, E., Gabra, H., Brown, R., Jewell, A., Nagaraj, S. H., Markham, E., Wilson, P. J., Ellul, J., McNally, O. M., Doyle, M. A., Vedururu, R., Stewart, C., Lengyel, E., Pearson, J. V., Waddell, N., DeFazio, A., Grimmond, S. M. & Bowtell, D. D. L., 28 May 2015, In : Nature. 521, 7553, p. 489-494 6 p.

Research output: Contribution to journalArticleResearchpeer-review

572 Citations (Scopus)
2014

Current management of advanced melanoma: a transformed landscape

Gyorki, D. E., Spillane, J., Speakman, D., Shackleton, M. & Henderson, M. A., 1 Sep 2014, In : ANZ Journal of Surgery. 84, 9, p. 612-617 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

9 Citations (Scopus)

Socrates: Identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads

Schröder, J., Hsu, A., Boyle, S. E., Macintyre, G., Cmero, M., Tothill, R. W., Johnstone, R. W., Shackleton, M. & Papenfuss, A. T., 1 Jan 2014, In : Bioinformatics. 30, 8, p. 1064-1072 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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44 Citations (Scopus)
2012

Human melanoma metastasis in NSG mice correlates with clinical outcome in patients

Quintana, E., Piskounova, E., Shackleton, M., Weinberg, D., Eskiocak, U., Fullen, D. R., Johnson, T. M. & Morrison, S. J., 7 Nov 2012, In : Science Translational Medicine. 4, 159, 11 p., 159ra149.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

MDM4 is a key therapeutic target in cutaneous melanoma

Gembarska, A., Luciani, F., Fedele, C. G., Russell, E. A., Dewaele, M., Villar, S., Zwolinska, A., Haupt, S., de Lange, J., Yip, D., Goydos, J., Haigh, J., Haupt, Y., Larue, L., Jochemsen, A., Shi, H., Moriceau, G., Lo, R. S., Ghanem, G., Shackleton, M. & 2 others, Bernal, F. & Marine, J-C., 2012, In : Nature Medicine. 18, 8, p. 1239 - 1247 9 p.

Research output: Contribution to journalArticleResearchpeer-review

180 Citations (Scopus)

Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ER alpha-positive tumors

Tikoo, A., Roh, V., Montgomery, K. G., Ivetac, I., Waring, P., Pelzer, R., Hare, L. M., Shackleton, M., Humbert, P. O. & Phillips, W. A., 2012, In : PLoS ONE. 7, 5, 13 p., e36924.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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40 Citations (Scopus)
2011

HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells

Carter, C. C., McNamara, L. A., Onafuwa-Nuga, A., Shackleton, M., Riddell IV, J., Bixby, D., Savona, M. R., Morrison, S. J. & Collins, K. L., 17 Mar 2011, In : Cell Host and Microbe. 9, 3, p. 223-234 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
68 Citations (Scopus)

Pulling RANK: Are some melanoma cells more malignant than others

Shackleton, M., 1 Jan 2011, In : Journal of Investigative Dermatology. 131, 4, p. 814-816 3 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
2010

Melanoma stem cells - Are there devils in the detail?

Shackleton, M., 1 Oct 2010, In : Pigment Cell and Melanoma Research. 23, 5, p. 693-694 2 p.

Research output: Contribution to journalLetterOtherpeer-review

5 Citations (Scopus)

Moving targets that drive cancer progression

Shackleton, M., 26 Aug 2010, In : The New England Journal of Medicine. 363, 9, p. 885-886 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

15 Citations (Scopus)

Normal stem cells and cancer stem cells: Similar and different

Shackleton, M., 1 Apr 2010, In : Seminars in Cancer Biology. 20, 2, p. 85-92 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

90 Citations (Scopus)

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

Quintana, E., Shackleton, M., Foster, H. R., Fullen, D. R., Sabel, M. S., Johnson, T. M. & Morrison, S. J., 16 Nov 2010, In : Cancer Cell. 18, 5, p. 510-523 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
411 Citations (Scopus)

Progress in understanding melanoma propagation

Shackleton, M. & Quintana, E., 1 Jan 2010, In : Molecular Oncology. 4, 5, p. 451-457 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

25 Citations (Scopus)
2009

Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

Shackleton, M., Quintana, E., Fearon, E. R. & Morrison, S. J., 4 Sep 2009, In : Cell. 138, 5, p. 822-829 8 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

Open Access
746 Citations (Scopus)

Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium

Shackleton, M., O'Reilly, L. A., Sutherland, K. D., Bath, M. L., Ellis, S., Strasser, A., Visvader, J. E. & Lindeman, G. J., 1 Apr 2009, In : Developmental Dynamics. 238, 4, p. 1010-1016 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Melanoma: Do we need a hatchet or a scalpel?

Johnson, T. M., Shackleton, M. J., Quintana, E., Fullen, D. R. & Sabel, M. S., 1 Mar 2009, In : Archives of Dermatology. 145, 3, p. 307-308 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

3 Citations (Scopus)
2008

Delineating the epithelial hierarchy in the mouse mammary gland

Asselin-Labat, M. L., Vaillant, F., Shackleton, M., Bouras, T., Lindeman, G. J. & Visvader, J. E., 1 Dec 2008, In : Cold Spring Harbor Symposia on Quantitative Biology. 73, p. 469-478 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
31 Citations (Scopus)

Efficient tumour formation by single human melanoma cells

Quintana, E., Shackleton, M., Sabel, M. S., Fullen, D. R., Johnson, T. M. & Morrison, S. J., 4 Dec 2008, In : Nature. 456, 7222, p. 593-598 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1352 Citations (Scopus)

The mammary progenitor marker CD61/β3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

Vaillant, F., Asselin-Labat, M. L., Shackleton, M., Forrest, N. C., Lindeman, G. J. & Visvader, J. E., 1 Oct 2008, In : Cancer Research. 68, 19, p. 7711-7717 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
234 Citations (Scopus)
2007

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

Asselin-Labat, M. L., Sutherland, K. D., Barker, H., Thomas, R., Shackleton, M., Forrest, N. C., Hartley, L., Robb, L., Grosveld, F. G., van der Wees, J., Lindeman, G. J. & Visvader, J. E., 1 Feb 2007, In : Nature Cell Biology. 9, 2, p. 201-209 9 p.

Research output: Contribution to journalArticleResearchpeer-review

561 Citations (Scopus)

The emerging picture of the mouse mammary stem cell

Vaillant, F., Asselin-Labat, M. L., Shackleton, M., Lindeman, G. J. & Visvader, J. E., 1 Jun 2007, In : Stem Cell Reviews. 3, 2, p. 114-123 10 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)
2006

Generation of a functional mammary gland from a single stem cell

Shackleton, M., Vaillant, F., Simpson, K. J., Stingl, J., Smyth, G. K., Asselin-Labat, M. L., Wu, L., Lindeman, G. J. & Visvader, J. E., 5 Jan 2006, In : Nature. 439, 7072, p. 84-88 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1430 Citations (Scopus)

Purification and unique properties of mammary epithelial stem cells

Stingl, J., Eirew, P., Ricketson, I., Shackleton, M., Vaillant, F., Choi, D., Li, H. I. & Eaves, C. J., 23 Feb 2006, In : Nature. 439, 7079, p. 993-997 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1128 Citations (Scopus)

Steroid hormone receptor status of mouse mammary stem cells

Asselin-Labat, M. L., Shackleton, M., Stingl, J., Vaillant, F., Forrest, N. C., Eaves, C. J., Visvader, J. E. & Lindeman, G. J., 19 Jul 2006, In : Journal of the National Cancer Institute. 98, 14, p. 1011-1014 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
232 Citations (Scopus)
2005

Characterization of antigen-specific CD8+ T lymphocyte responses in skin and peripheral blood following intradermal peptide vaccination

Chen, Q., Jackson, H., Shackleton, M., Parente, P., Hopkins, W., Sturrock, S., MacGregor, D., Maraskovsky, E., Tai, T. Y., Dimopoulos, N., Masterman, K. A., Luke, T., Davis, I. D., Chen, W. & Cebon, J., 9 Mar 2005, In : Cancer Immunity. 5, 5.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Erratum: Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans (Proceedings of the National Academy of Sciences of the United States of America (July 20, 2004) 101, 29 (10697-10702))

Davis, I. D., Chen, W., Jackson, H., Parente, P., Shackleton, M., Hopkins, W., Chen, Q., Dimopoulos, N., Luke, T., Murphy, R., Scott, A. M., Maraskovsky, E., McArthur, G., MacGregor, D., Sturrock, S., Tai, T. Y., Green, S., Cuthbertson, A., Maher, D., Miloradovic, L. & 8 others, Mitchell, S. V., Ritter, G., Jungbluth, A. A., Chen, Y. T., Gnjatic, S., Hoffman, E. W., Old, L. J. & Cebon, J. S., 5 Jul 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 27, 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

3 Citations (Scopus)