If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

Senior Principal Research Fellow

Research Group Head, Endocrinology and Immunophysiology Laboratory

Co-Deputy Head, Centre for Reproductive Health

Professor Mark Hedger has worked in men’s reproductive health since completing his PhD at Monash University in 1984. Subsequently, he received an NIH Visiting Fellowship to work in the Gamete Biology Section, Laboratory of Reproductive and Developmental Toxicology at the National Institute of Environmental Health Sciences in North Carolina, USA. In 1987, he returned to Melbourne to take up an Australian Postdoctoral Research Fellowship with the Department of Anatomy at Monash University.

From 1991 until 1994 Professor Hedger was an inaugural NHMRC Wright Fellow at the Institute of Reproduction and Development (now the Hudson Institute of Medical Research). In 1993 he was appointed an Institute Senior Scientist/Laboratory Head, and in 1996, Deputy-Director of the Centre for Reproduction and Development. In 2001 he was awarded an NHMRC Senior Research Fellowship, a position he continued to hold until 2016. He received an Associate Professorial Fellowship through Monash University’s Department of Physiology in 2003, and is currently a Senior Principal Research Fellow at the Hudson Institute of Medical Research and Professor in the Department of Molecular and Translational Sciences at Monash University. He has published more than 150 scholarly reports and scientific papers, principally in the fields of male reproductive tract biology, activin biology and inflammatory disease in various tissues. His research was recognized as one of the NHMRC’s “10 of the Best” Research Projects in 2008. He also serves on the editorial board of the Andrologia, and is a Section Editor for the Journal of Reproductive Immunology.

Professor Hedger is a member of several Australian and international scientific societies and was President of the Society for Reproductive Biology (2009 -2012). He is a Fellow of the Society for Reproductive Biology and a Fellow of the Society for the Study of Reproduction (USA).

Keywords

  • activin
  • follistatin
  • fertility
  • inflammation
  • immunity
  • testis
  • epididymis
  • macrophages

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2000 2022

Research Output 1983 2019

Activin A target genes are differentially expressed between normal and neoplastic adult human testes: clues to gonocyte fate choice

Szarek, M., Bergmann, M., Konrad, L., Schuppe, H. C., Kliesch, S., Hedger, M. P. & Loveland, K. A. L., 1 Jan 2019, In : Andrology. 7, 1, p. 31-41 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro

Richani, D., Constance, K., Lien, S., Agapiou, D., Stocker, W. A., Hedger, M. P., Ledger, W., Thompson, J. G., Robertson, D. M., Mottershead, D. G., Walton, K. L., Harrison, C. A. & Gilchrist, R., 1 Apr 2019, In : Endocrinology. 160, 4, p. 853-862 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Dexamethasone improves therapeutic outcomes in a preclinical bacterial epididymitis mouse model

Klein, B., Pant, S., Bhushan, S., Kautz, J., Rudat, C., Kispert, A., Pilatz, A., Wijayarathna, R., Middendorff, R., Loveland, K., Hedger, M. & Meinhardt, A., Jul 2019, In : Human Reproduction. 34, 7, p. 1195-1205 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging

Lepletier, A., Hun, M. L., Hammett, M. V., Wong, K., Naeem, H., Hedger, M., Loveland, K. & Chidgey, A. P., 25 Jun 2019, In : Cell Reports. 27, 13, p. 3887–3901–e4 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Comparative analysis of activins A and B in the adult mouse epididymis and vas deferens

Wijayarathna, R., de Kretser, D. M., Sreenivasan, R., Ludlow, H., Middendorff, R., Meinhardt, A., Loveland, K. L. & Hedger, M. P., 1 Jan 2018, In : Reproduction. 155, 1, p. 15-23 9 p.

Research output: Contribution to journalArticleResearchpeer-review