Projects per year
Personal profile
Biography
Senior Principal Research Fellow
Research Group Head, Endocrinology and Immunophysiology Laboratory
Co-Deputy Head, Centre for Reproductive Health
Professor Mark Hedger has worked in men’s reproductive health since completing his PhD at Monash University in 1984. Subsequently, he received an NIH Visiting Fellowship to work in the Gamete Biology Section, Laboratory of Reproductive and Developmental Toxicology at the National Institute of Environmental Health Sciences in North Carolina, USA. In 1987, he returned to Melbourne to take up an Australian Postdoctoral Research Fellowship with the Department of Anatomy at Monash University.
From 1991 until 1994 Professor Hedger was an inaugural NHMRC Wright Fellow at the Institute of Reproduction and Development (now the Hudson Institute of Medical Research). In 1993 he was appointed an Institute Senior Scientist/Laboratory Head, and in 1996, Deputy-Director of the Centre for Reproduction and Development. In 2001 he was awarded an NHMRC Senior Research Fellowship, a position he continued to hold until 2016. He received an Associate Professorial Fellowship through Monash University’s Department of Physiology in 2003, and is currently a Senior Principal Research Fellow at the Hudson Institute of Medical Research and Professor in the Department of Molecular and Translational Sciences at Monash University. He has published more than 150 scholarly reports and scientific papers, principally in the fields of male reproductive tract biology, activin biology and inflammatory disease in various tissues. His research was recognized as one of the NHMRC’s “10 of the Best” Research Projects in 2008. He also serves on the editorial board of the Andrologia, and is a Section Editor for the Journal of Reproductive Immunology.
Professor Hedger is a member of several Australian and international scientific societies and was President of the Society for Reproductive Biology (2009 -2012). He is a Fellow of the Society for Reproductive Biology and a Fellow of the Society for the Study of Reproduction (USA).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- activin
- follistatin
- fertility
- inflammation
- immunity
- testis
- epididymis
- macrophages
Collaborations and top research areas from the last five years
Projects
- 16 Finished
-
Treating Inflammation in the Male Reproductive Tract
Hedger, M. & Meinhardt, A.
1/01/20 → 31/12/23
Project: Research
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IRTG: International Research Training Grant (IRTG)_Renewal of Molecular pathogenesis of male reproductive disorders project
Meinhardt, A., Loveland, K., Bhushan, S., Ellem, S. J., Hedger, M., O'Bryan, M., O'Donnell, L., Stanton, P., Risbridger, G., Baker, M. A., Hobbs, R., Loveland, B. E., Exintaris, B., Western, P., McLachlan, R., Whittaker, M., Wagenlehner, F. M. E., Bergmann, M., Diemer, T., Fietz, D., Fijak, M., Konrad, L., Linn, T., Middendorff, R., Pilatz, A. M. E., Schagdarsurengin, U., Schuppe, H. C., Steger, K. & Scheiner-Bobis, G.
1/10/17 → 31/03/22
Project: Research
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Regulation of immune responses in the adult testis and male reproductive health
Hedger, M., Loveland, K., Mansell, A. & Meinhardt, A.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/17 → 31/12/19
Project: Research
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Activin and its binding protein, follistatin regulate functions of the epididymis and vas deferens
Hedger, M., Loveland, K., Meinhardt, A. & de Kretser, D.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/14 → 31/12/16
Project: Research
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Activin A and CCR2 regulate macrophage function in testicular fibrosis caused by experimental autoimmune orchitis
Peng, W., Kepsch, A., Kracht, T. O., Hasan, H., Wijayarathna, R., Wahle, E., Pleuger, C., Bhushan, S., Günther, S., Kauerhof, A. C., Planinić, A., Fietz, D., Schuppe, H. C., Wygrecka, M., Loveland, K. L., Ježek, D., Meinhardt, A., Hedger, M. P. & Fijak, M., Dec 2022, In: Cellular and Molecular Life Sciences. 79, 12, 24 p., 602.Research output: Contribution to journal › Article › Research › peer-review
Open Access11 Citations (Scopus) -
Examination of testicular lumicrine regulation of activins and immunoregulatory genes in the epididymal caput
Wijayarathna, R., Genovese, R., Meinhardt, A., Loveland, K. L., Groome, N. P., Hinton, B. T. & Hedger, M. P., Jan 2022, In: Andrology. 10, 1, p. 190-201 12 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
Regulation of macrophage number and gene transcript levels by activin A and its binding protein, follistatin, in the testes of adult mice
Biniwale, S., Wijayarathna, R., Pleuger, C., Bhushan, S., Loveland, K. L., Meinhardt, A. & Hedger, M. P., Jun 2022, In: Journal of Reproductive Immunology. 151, 8 p., 103618.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
The changing landscape of immune cells in the fetal mouse testis
Hosseini, S., Moody, S. C., Fietz, D., Indumathy, S., Schuppe, H. C., Hedger, M. P. & Loveland, K. L., Oct 2022, In: Histochemistry and Cell Biology. 158, 4, p. 345–368 24 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis
Pleuger, C., Ai, D., Hoppe, M. L., Winter, L. T., Bohnert, D., Karl, D., Guenther, S., Epelman, S., Kantores, C., Fijak, M., Ravens, S., Middendorff, R., Mayer, J. U., Loveland, K. L., Hedger, M., Bhushan, S. & Meinhardt, A., 14 Dec 2022, In: eLife. 11, 34 p., e82193.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Citations (Scopus)