Projects per year
Personal profile
Biography
Mark A Febbraio
Professor Mark Febbraio is a Senior Principal Research Fellow of the NHMRC, and the Head of the Cellular and Molecular Metabolism Laboratory within the Drug Discovery Program at Monash Institute of Pharmaceutical Sciences, Monash University Australia. He is also the CSO of N-Gene Research Laboratories Inc., a USA based Biotechnology Company and the Founder and CSO of the recently incorporated company Kinomedica. His research is focussed on understanding mechanisms associated with exercise, obesity, type 2 diabetes and cancer and his aim is to develop novel drugs to treat lifestyle related diseases. He has authored over 260 peer reviewed papers in leading journals, has over 35,000 career citations and an H factor of 105. He has won prizes at international, national and institutional levels including the A K McIntyre Prize for significant contributions to Australian Physiological Science (1999), the ESA/ADS Joint Plenary Lecture (2009), the Sandford Skinner Oration from the University of Melbourne (2011), Eureka Scientific Prize Finalist (2013) and the Kellion Award for the Australian Diabetes Society (2017).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Cell Metabolism
- Diabetes
- Cancer Biology
- Exercise physiology
Network
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Mapping and defining inter-organ cross talk during exercise
Febbraio, M. & Ramm, G.
16/08/22 → 15/08/25
Project: Research
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Targeting Immune Checkpoints In Obesity-Driven HCC
Wiede, F., Tiganis, T., Darcy, P., Johnstone, R. W., McLean, C. & Febbraio, M.
1/07/21 → 30/06/23
Project: Research
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Development of novel therapies to treat obesity related metabolic diseases
1/01/21 → 31/12/25
Project: Research
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Role of extracellular vesicles in exercise-induced protection of liver steatosis and insulin resistance
Febbraio, M., Karin, M. & Whitham, M.
Diabetes Australia, Monash University – Internal School Contribution
1/01/22 → 31/12/22
Project: Research
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NAFLD, NASH and Hepatocellular carcinoma: Mechanisms & Potential Treatments
Febbraio, M., Karin, M. & Shackel, N.
1/07/19 → 31/12/20
Project: Research
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Diet-induced gut dysbiosis and inflammation: Key drivers of obesity-driven NASH
Kang, G. G., Trevaskis, N. L., Murphy, A. J. & Febbraio, M. A., 20 Jan 2023, In: iScience. 26, 1, 23 p., 105905.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus) -
Circulating Ceramides- Are Origins Important for Sphingolipid Biomarkers and Treatments?
Mah, M., Febbraio, M. & Turpin-Nolan, S., 27 Jul 2021, In: Frontiers in Endocrinology. 12, 12 p., 684448.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access12 Citations (Scopus) -
Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms
Riddy, D. M., Kammoun, H. L., Murphy, A. J., Bosnyak-Gladovic, S., De La Fuente Gonzalez, R., Merlin, J., Ziemann, M., Fabb, S., Pierce, T. L., Diepenhorst, N., Rueda, P., El-Osta, A., Gautier, J. F., Venteclef, N., Charman, W. N., Christopoulos, A., Sexton, P. M., Summers, R. J., Febbraio, M. A., Delerive, P., & 1 others , Nov 2021, In: BMJ Open Diabetes Research and Care. 9, 2, 13 p., e002285.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
IL-6 family cytokines as potential therapeutic strategies to treat metabolic diseases
Zhao, J., Turpin-Nolan, S. & Febbraio, M. A., Aug 2021, In: Cytokine. 144, 7 p., 155549.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access6 Citations (Scopus) -
Stable isotopic tracer phospholipidomics reveals contributions of key phospholipid biosynthetic pathways to low hepatocyte phosphatidylcholine to phosphatidylethanolamine ratio induced by free fatty acids
Peng, K. Y., Barlow, C. K., Kammoun, H., Mellett, N. A., Weir, J. M., Murphy, A. J., Febbraio, M. A. & Meikle, P. J., Mar 2021, In: Metabolites. 11, 3, 18 p., 188.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)