Projects per year
Personal profile
Biography
Mark A Febbraio
Professor Mark Febbraio is a Senior Principal Research Fellow of the NHMRC, and the Head of the Cellular and Molecular Metabolism Laboratory within the Drug Discovery Program at Monash Institute of Pharmaceutical Sciences, Monash University Australia. He is also the CSO of N-Gene Research Laboratories Inc., a USA based Biotechnology Company and the Founder and CSO of the recently incorporated company Kinomedica. His research is focussed on understanding mechanisms associated with exercise, obesity, type 2 diabetes and cancer and his aim is to develop novel drugs to treat lifestyle related diseases. He has authored over 260 peer reviewed papers in leading journals, has over 35,000 career citations and an H factor of 105. He has won prizes at international, national and institutional levels including the A K McIntyre Prize for significant contributions to Australian Physiological Science (1999), the ESA/ADS Joint Plenary Lecture (2009), the Sandford Skinner Oration from the University of Melbourne (2011), Eureka Scientific Prize Finalist (2013) and the Kellion Award for the Australian Diabetes Society (2017).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Cell Metabolism
- Diabetes
- Cancer Biology
- Exercise physiology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Advancing Preclinical Development of Novel GPCR-targeted Therapeutics for Heart Failure
Ritchie, R. (Primary Chief Investigator (PCI)), Figtree, G. A. (Chief Investigator (CI)), Qin, C. H. (Chief Investigator (CI)), May, L. (Chief Investigator (CI)), Nicholls, S. (Chief Investigator (CI)), Taylor, A. (Chief Investigator (CI)), Yang, J. Y. H. (Chief Investigator (CI)), Shackleford, D. (Chief Investigator (CI)), Schiattarella, G. (Chief Investigator (CI)), Pinto, A. (Chief Investigator (CI)), Drummond, G. (Chief Investigator (CI)), Horowitz, J. D. (Chief Investigator (CI)), Bubb, K. (Chief Investigator (CI)), Ng, H. H. (Chief Investigator (CI)), Vecchio, L. (Associate Investigator (AI)), Nelson, A. (Associate Investigator (AI)), Kirkpatrick, C. (Associate Investigator (AI)), McDonald, C. (Associate Investigator (AI)), Febbraio, M. (Associate Investigator (AI)), Vinh, A. (Associate Investigator (AI)), Odiba, J. (Associate Investigator (AI)), Brown, H. (Associate Investigator (AI)) & Stupple, P. (Chief Investigator (CI))
1/02/23 → 31/01/26
Project: Research
-
Development of novel therapies to treat obesity related metabolic diseases
Febbraio, M. (Primary Chief Investigator (PCI))
1/01/21 → 31/12/25
Project: Research
-
Targeting gut ceramides - a new way to improve systemic insulin sensitivity
Turpin-Nolan, S. (Primary Chief Investigator (PCI)) & Febbraio, M. (Chief Investigator (CI))
15/01/24 → 14/01/25
Project: Research
-
Mapping and defining inter-organ cross talk during exercise
Febbraio, M. (Primary Chief Investigator (PCI)) & Ramm, G. (Partner Investigator (PI))
29/06/22 → 31/12/24
Project: Research
-
Role of extracellular vesicles in exercise-induced protection of liver steatosis and insulin resistance
Febbraio, M. (Primary Chief Investigator (PCI)), Karin, M. (Chief Investigator (CI)) & Whitham, M. (Chief Investigator (CI))
Diabetes Australia, Monash University – Internal School Contribution
1/01/22 → 31/12/22
Project: Research
-
Exercise training improves long-term memory in obese mice
Fuller, O. K., Egan, C. L., Robinson, T. L., Perera, N., Latchman, H. K., Terry, L. V., McLennan, E. D., Chavez, C., Burrows, E. L., Scott, J. W., Murphy, R. M., van Praag, H., Whitham, M. & Febbraio, M. A., 1 Feb 2024, In: Life Metabolism. 3, 1, 14 p., load043.Research output: Contribution to journal › Article › Research
Open Access2 Citations (Scopus) -
High-fat feeding drives the intestinal production and assembly of C16:0 ceramides in chylomicrons
Mah, M. S. M., Cao, E., Anderson, D., Escott, A., Tegegne, S., Gracia, G., Schmitz, J., Brodesser, S., Zaph, C., Creek, D. J., Hong, J., Windsor, J. A., Phillips, A. R., Trevaskis, N. L., Febbraio, M. A. & Turpin-Nolan, S. M., 23 Aug 2024, In: Science Advances. 10, 34, 14 p., eadp2254.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
CaMKK2 as an emerging treatment target for bipolar disorder
Kaiser, J., Nay, K., Horne, C. R., McAloon, L. M., Fuller, O. K., Muller, A. G., Whyte, D. G., Means, A. R., Walder, K., Berk, M., Hannan, A. J., Murphy, J. M., Febbraio, M. A., Gundlach, A. L. & Scott, J. W., Nov 2023, In: Molecular Psychiatry. 28, 11, p. 4500–4511 12 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access8 Citations (Scopus) -
Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity
Martin, S. D., Connor, T., Sanigorski, A., McEwen, K. A., Henstridge, D. C., Nijagal, B., De Souza, D., Tull, D. L., Meikle, P. J., Kowalski, G. M., Bruce, C. R., Gregorevic, P., Febbraio, M. A., Collier, F. M., Walder, K. R. & McGee, S. L., 1 Dec 2023, In: Cell Death & Disease. 14, 12, 13 p., 787.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Diet-induced gut dysbiosis and inflammation: Key drivers of obesity-driven NASH
Kang, G. G., Trevaskis, N. L., Murphy, A. J. & Febbraio, M. A., 20 Jan 2023, In: iScience. 26, 1, 23 p., 105905.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access42 Citations (Scopus)