Accepting PhD Students

PhD projects

Our research is focused on identifying genes, proteins and pathways that are important in metabolic disease and certain types of obesity related cancer, and then to develop pharmaceutical therapies that either activate or block the pathway of interest. We currently have several drug candidates that we are exploring and PhD projects that address these areas.

1993 …2021

Research output per year

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Personal profile

Biography

Mark A Febbraio 

Professor Mark Febbraio is a Senior Principal Research Fellow of the NHMRC, and the Head of the Cellular and Molecular Metabolism Laboratory within the Drug Discovery Program at Monash Institute of Pharmaceutical Sciences, Monash University Australia. He is also the CSO of N-Gene Research Laboratories Inc., a USA based Biotechnology Company and the Founder and CSO of the recently incorporated company Kinomedica. His research is focussed on understanding mechanisms associated with exercise, obesity, type 2 diabetes and cancer and his aim is to develop novel drugs to treat lifestyle related diseases. He has authored over 260 peer reviewed papers in leading journals, has over 35,000 career citations and an H factor of 105. He has won prizes at international, national and institutional levels including the A K McIntyre Prize for significant contributions to Australian Physiological Science (1999), the ESA/ADS Joint Plenary Lecture (2009), the Sandford Skinner Oration from the University of Melbourne (2011), Eureka Scientific Prize Finalist (2013) and the Kellion Award for the Australian Diabetes Society (2017). 

Research area keywords

  • Cell Metabolism
  • Diabetes
  • Cancer Biology
  • Exercise physiology

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Projects

Research Output

Intravascular Follistatin gene delivery improves glycemic control in a mouse model of type 2 diabetes

Davey, J. R., Estevez, E., Thomson, R. E., Whitham, M., Watt, K. I., Hagg, A., Qian, H., Henstridge, D. C., Ludlow, H., Hedger, M. P., McGee, S. L., Coughlan, M. T., Febbraio, M. A. & Gregorevic, P., Apr 2020, In : The FASEB Journal. 34, 4, p. 5697-5714 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Sex-specific adipose tissue imprinting of regulatory T cells

Vasanthakumar, A., Chisanga, D., Blume, J., Gloury, R., Britt, K., Henstridge, D. C., Zhan, Y., Torres, S. V., Liene, S., Collins, N., Cao, E., Sidwell, T., Li, C., Spallanzani, R. G., Liao, Y., Beavis, P. A., Gebhardt, T., Trevaskis, N., Nutt, S. L., Zajac, J. D. & 5 others, Davey, R. A., Febbraio, M. A., Mathis, D., Shi, W. & Kallies, A., 26 Mar 2020, In : Nature. 579, 7800, p. 581–585+ 29 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice

Whitham, M., Pal, M., Petzold, T., Hjorth, M., Egan, C. L., Brunner, J. S., Estevez, E., Iliades, P., Zivanovic, B., Reibe, S., Hughes, W. E., Findeisen, M., Hidalgo, J. & Febbraio, M. A., 30 Sep 2019, In : American Journal of Physiology - Endocrinology and Metabolism. 317, 4, p. E597-E604 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Can microbes increase exercise performance in athletes?

Turpin-Nolan, S. M., Joyner, M. J. & Febbraio, M. A., 1 Nov 2019, In : Nature Reviews Endocrinology. 15, 11, p. 629-630 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Metabolic control and sex: A focus on inflammatory-linked mediators

Henstridge, D. C., Abildgaard, J., Lindegaard, B. & Febbraio, M. A., 28 Feb 2019, In : British Journal of Pharmacology. 176, 21, p. 4193-4207 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)