Projects per year
Personal profile
Biography
Mark works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Senior Lecturer and Lab Head of the Macro Therapeutics Lab within the Department of Pharmacology
Biography
Dr Mark Del Borgo is an internationally recognised member of the peptide science community with extensive experience in the pharmacological characterisation of peptides within various biological settings. Dr Mark Del Borgo received his PhD in pharmacology in 2005 from the University of Melbourne and immediately became a research fellow in the Department of Chemistry at the University of Queensland (2005-2007). He then took up a teaching only position in the Department of Medicinal Chemistry at the University of Kansas (2007-2008). Since 2009, He has been a research fellow within the Department of Biochemistry & Molecular Biology at Monash University. He was the first person to demonstrate that peptides derived from β-amino acids are able to self-assemble into a wide range of fibrous materials (published in Angew. Chem. Int. Ed.). These materials form a platform technology with many applications in regenerative medicine, bioengineering and drug delivery that he envisages will be the focus of many high-quality publications and be of interest to commercial partners. He has recently been promoted to Senior Lecturer within the Department of Pharmacology and Head of the Macro Therapeutics Lab on the back of his rising profile.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Pharmacology, PhD, Design, Synthesis and Analysis of Single-chain Mimetics of Relaxin and Insulin-Like Peptide 3, University of Melbourne
Award Date: 15 Dec 2005
BSc(Hons), University of Melbourne
Award Date: 16 Nov 2000
Research area keywords
- Peptide materials
- Bioengineering
- Drug delivery
- Drug Development
Collaborations and top research areas from the last five years
Projects
- 5 Finished
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Synthesis of novel peptide mimics for use as anti-fibrotic agents
Del Borgo, M. (Primary Chief Investigator (PCI)) & Widdop, R. (Chief Investigator (CI))
Monash University – Internal University Contribution, Monash University – Internal Department Contribution, Monash University – Internal Faculty Contribution
8/03/21 → 4/03/22
Project: Research
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Novel inhibitors of SARS coronaviruses targeting ACE2
Drummer, H. (Primary Chief Investigator (PCI)), Widdop, R. (Chief Investigator (CI)), Aguilar, M. (Chief Investigator (CI)), Shehabi, Y. (Chief Investigator (CI)), Del Borgo, M. (Chief Investigator (CI)), Coulibaly, F. (Chief Investigator (CI)), McMahon, J. (Chief Investigator (CI)), Kulkarni, K. (Chief Investigator (CI)), Lambert, P. (Chief Investigator (CI)) & McIntosh, M. (Chief Investigator (CI))
1/06/20 → 28/02/21
Project: Research
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Atomic Scale Structure of Self-Assembled Lipidated Peptide Nanomaterials
Williams-Noonan, B. J., Kulkarni, K., Todorova, N., Franceschi, M., Wilde, C., Borgo, M. P. D., Serpell, L. C., Aguilar, M. I. & Yarovsky, I., 13 Jun 2024, In: Advanced Materials. 36, 24, 16 p., 2311103.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Targeting the Angiotensin AT2 Receptor to Treat Cardiac Fibrosis and Heart Failure
Wang, Y., Ferens, D., Salimova, E., Borgo, M., Aguilar, M., Gaspari, T., Nguyen, L., Zhu, L., Xu, P., Denton, K., Wang, M., Samuel, C. & Widdop, R., Aug 2024, In: Heart Lung and Circulation. 33, Supplement 4, p. S486 1 p., 783.Research output: Contribution to journal › Meeting Abstract › peer-review
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A comparison of fixation methods for SEM analysis of self-assembling peptide hydrogel nanoarchitecture
McFetridge, M. L., Kulkarni, K., Hilsenstein, V., Del Borgo, M. P., Aguilar, M. I. & Ricardo, S. D., 21 Jan 2023, In: Nanoscale. 15, 3, p. 1431-1440 10 p.Research output: Contribution to journal › Article › Research › peer-review
10 Citations (Scopus) -
A switch in N-terminal capping of β-peptides creates novel self-assembled nanoparticles
Chen, Y. K., Simon, I. A., Maslov, I., Oyarce-Pino, I. E., Kulkarni, K., Hopper, D., Aguilar, M. I., Vankadari, N., Broughton, B. R. & Del Borgo, M. P., 9 Oct 2023, In: RSC Advances. 13, 42, p. 29401-29407 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Elucidating the cell penetrating properties of self-assembling β-peptides
McFetridge, M. L., Kulkarni, K., Lee, T.-H., Del Borgo, M. P., Aguilar, M. I. & Ricardo, S. D., 28 Sept 2023, In: Nanoscale. 36, p. 14971–14980 10 p.Research output: Contribution to journal › Article › Research › peer-review