20122019
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Personal profile

Biography

Dr Marion Boudes is a structural biologist, with expertise in cryogenic electron microscopy (cryo-EM), X-ray crystallography, SAXS, and protein biochemistry. Her current research interests include using cryo-EM to elucidate the structure and dynamics of large protein complexes involved in genome regulation. 

During her PhD in Structural Biology from University Paris-Sud (2008-2011), Dr Boudes studied key activators of transcription in bacterial pathogens. She subsequently joined the Structural Virology Laboratory at Monash University under Associate Professor Fasséli Coulibaly’s supervision, where she specialised in X-ray microcrystallography and developed the innovative method of in cellulo crystallography.

In 2017, Dr Boudes joined the laboratory of Dr Dominika Elmlund and Dr Hans Elmlund, both of whom are internationally recognised experts in the field of single-particle cryo-Electron Microscopy (cryo-EM). Since that time, Dr Boudes has gained significant skills in cryo-EM as well as transcription biochemistry, and has also designed original methods for sample stabilisation. Dr Boudes is currently supported by a Senior Postdoctoral Fellowship from the Faculty of Medicine, Nursing & Health Sciences (FMNHS).

Keywords

  • Cryo-EM
  • X-Ray Crystallography
  • Protein Biochemistry
  • Transcription Regulation
  • Epigenetics

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Research Output 2012 2019

AgarFix: Simple and accessible stabilization of challenging single-particle cryo-EM specimens through crosslinking in a matrix of agar

Adamus, K., Le, S. N., Elmlund, H., Boudes, M. & Elmlund, D., 16 Jul 2019, (Accepted/In press) In : Journal of Structural Biology. 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Supramolecular protein cages constructed from a crystalline protein matrix

Negishi, H., Abe, S., Yamashita, K., Hirata, K., Niwase, K., Boudes, M., Coulibaly, F., Mori, H. & Ueno, T., 1 Jan 2018, In : Chemical Communications. 54, 16, p. 1988-1991 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Microcrystallography of protein crystals and in cellulo diffraction

Boudes, M., Garriga, D. & Coulibaly, F., 21 Jul 2017, In : Journal of Visualized Experiments. 2017, 125, e55793.

Research output: Contribution to journalArticleOtherpeer-review

A pipeline for structure determination of in vivo-grown crystals using in cellulo diffraction

Boudes, M., Garriga, D., Fryga, A., Caradoc-Davies, T. & Coulibaly, F., 2016, In : Acta Crystallographica Section D: Structural Biology. 72, 4, p. 576-585 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Photoactivatable CO release from engineered protein crystals to modulate NF-κB activation

Tabe, H., Shimoi, T., Boudes, M., Abe, S., Coulibaly, F., Kitagawa, S., Mori, H. & Ueno, T., 1 Mar 2016, In : Chemical Communications. 52, 24, p. 4545-4548 4 p.

Research output: Contribution to journalArticleResearchpeer-review