Projects per year
Personal profile
Biography
Dr Marina Harper works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Research Fellow. Marina has extensive research experience microbial genetics and molecular biology. The focus of her research is on pathogenic Gram-negative bacteria and their virulence factors, and how the expression of these factors is regulated. This work utilizes a wide range of molecular techniques, including mutagenesis, combined with a range of cutting edge techniques including next generation genomic and transcriptomic analyses. Dr Harper is a world expert on the biology of the Pasteurella multocida, together with collaborators her work has shown the importance of lipopolysaccharide (LPS) and capsule in virulence, elucidated the structure of the LPS and revealed that LPS is a critical protective antigen in killed whole-cell vaccines but is not a protective antigen in live attenuated vaccines.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Bacterial Pathogenesis
- Pasteurella Multocida
- Acinetobacter Baumannii
- lipopolysaccharide
- Molecular Biology
- transcriptomics
Network
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Role of Pasteurella surface polysaccharides in pathogenesis and immunity
Boyce, J., Harper, M. & Cox, A.
10/05/21 → 9/05/24
Project: Research
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Co-opting bacterial weaponry: Manipulation of the Acinetobacter type VI secretion system for targeted killing of bacteria
Boyce, J., Harper, M. & Drinkwater, N.
1/01/19 → 31/12/22
Project: Research
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Overcoming multidrug-resistant hypermutable Pseudomonas aeruginosa via antibiotic combinations
Landersdorfer, C., Oliver, A., Harper, M. & Nation, R.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
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NleB2 from enteropathogenic Escherichia coli is a novel arginine-glucose transferase effector
Giogha, C., Scott, N. E., Lung, T. W. F., Pollock, G. L., Harper, M., Goddard-Borger, E. D., Pearson, J. S. & Hartland, E. L., Jun 2021, In: PLoS Pathogens. 17, 6, 29 p., e1009658.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Phosphorylation of Extracellular Proteins in Acinetobacter baumannii in Sessile Mode of Growth
Massier, S., Robin, B., Mégroz, M., Wright, A., Harper, M., Hayes, B., Cosette, P., Broutin, I., Boyce, J. D., Dé, E. & Hardouin, J., 1 Oct 2021, In: Frontiers in Microbiology. 12, 13 p., 738780.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
The capsular polysaccharides of Pasteurella multocida serotypes B and E: Structural, genetic and serological comparisons
Michael, F. S., Cairns, C. M., Fleming, P., Vinogradov, E. V., Boyce, J. D., Harper, M. & Cox, A. D., Mar 2021, In: Glycobiology. 31, 3, p. 307-314 8 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Mechanisms of Polymyxin Resistance
Moffatt, J. H., Harper, M. & Boyce, J. D., Jul 2019, Polymyxin Antibiotics: From Laboratory Bench to Bedside. Li, J., Nation, R. L. & Kaye, K. S. (eds.). 1st ed. Switzerland: Springer, p. 55-71 17 p. (Advances in Experimental Medicine and Biology; vol. 1145).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
54 Citations (Scopus) -
Polymyxin resistance in Klebsiella pneumoniae: multifaceted mechanisms utilized in the presence and absence of the plasmid-encoded phosphoethanolamine transferase gene mcr-1
Nang, S. C., Han, M-L., Yu, H. H., Wang, J., Torres, V. V. L., Dai, C., Velkov, T., Harper, M. & Li, J., 1 Nov 2019, In: Journal of Antimicrobial Chemotherapy. 74, 11, p. 3190-3198 9 p.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus)