Projects per year
Personal profile
Biography
Dr Marina Harper works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Research Fellow. Marina has extensive research experience microbial genetics and molecular biology. The focus of her research is on pathogenic Gram-negative bacteria and their virulence factors, and how the expression of these factors is regulated. This work utilizes a wide range of molecular techniques, including mutagenesis, combined with a range of cutting edge techniques including next generation genomic and transcriptomic analyses. Dr Harper is a world expert on the biology of the Pasteurella multocida, together with collaborators her work has shown the importance of lipopolysaccharide (LPS) and capsule in virulence, elucidated the structure of the LPS and revealed that LPS is a critical protective antigen in killed whole-cell vaccines but is not a protective antigen in live attenuated vaccines.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Bacterial Pathogenesis
- Pasteurella Multocida
- Acinetobacter Baumannii
- lipopolysaccharide
- Molecular Biology
- transcriptomics
Collaborations and top research areas from the last five years
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Role of Pasteurella surface polysaccharides in pathogenesis and immunity
Boyce, J., Harper, M. & Cox, A.
1/06/21 → 30/05/24
Project: Research
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Overcoming multidrug-resistant hypermutable Pseudomonas aeruginosa via antibiotic combinations
Landersdorfer, C., Oliver, A., Harper, M. & Nation, R.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
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Co-opting bacterial weaponry: Manipulation of the Acinetobacter type VI secretion system for targeted killing of bacteria
Boyce, J., Harper, M. & Drinkwater, N.
1/01/19 → 31/12/22
Project: Research
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Genome-Wide Investigation of Pasteurella multocida Identifies the Stringent Response as a Negative Regulator of Hyaluronic Acid Capsule Production
Smallman, T. R., Williams, G. C., Harper, M. & Boyce, J. D., Apr 2022, In: Microbiology Spectrum. 10, 2, 16 p., e00195-22.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Polymyxin causes cell envelope remodelling and stress responses in mcr-1-harbouring Escherichia coli
Nang, S. C., Li, M., Harper, M., Mandela, E., Bergen, P. J., Rolain, J. M., Zhu, Y., Velkov, T. & Li, J., Feb 2022, In: International Journal of Antimicrobial Agents. 59, 2, 7 p., 106505.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
The Role and Targets of the RNA-Binding Protein ProQ in the Gram-Negative Bacterial Pathogen Pasteurella multocida
Gulliver, E. L., Sy, B. M., Wong, J. L., Deveson Lucas, D. S., Powell, D. R., Harper, M., Tree, J. J. & Boyce, J. D., Apr 2022, In: Journal of Bacteriology. 204, 4, p. 1-22 22 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
NleB2 from enteropathogenic Escherichia coli is a novel arginine-glucose transferase effector
Giogha, C., Scott, N. E., Lung, T. W. F., Pollock, G. L., Harper, M., Goddard-Borger, E. D., Pearson, J. S. & Hartland, E. L., Jun 2021, In: PLoS Pathogens. 17, 6, 29 p., e1009658.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Phosphorylation of Extracellular Proteins in Acinetobacter baumannii in Sessile Mode of Growth
Massier, S., Robin, B., Mégroz, M., Wright, A., Harper, M., Hayes, B., Cosette, P., Broutin, I., Boyce, J. D., Dé, E. & Hardouin, J., 1 Oct 2021, In: Frontiers in Microbiology. 12, 13 p., 738780.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus)