Projects per year
Personal profile
Biography
Associate Professor Margaret Hibbs
Department of Immunology - Leukocyte Signalling Laboratory
Margaret Hibbs is an Associate Professor in the Department of Immunology, within the Central Clinical School, and Group leader of the Leukocyte Signalling Laboratory.
The Leukocyte Signaling Laboratory is studying signaling pathways that play a role in immune system development and function. We are primarily interested in what regulates the development of immunity and we are trying to understand the processes that are perturbed when autoimmunity and inflammatory diseases develop. We are also interested in understanding what regulates haematopoiesis or blood cell development, and believe that this will give us a greater understanding of the signals that go awry in the development of blood cell cancers. The lab also has a major interest in understanding the mechanisms underlying chronic inflammatory lung disease and we aim to identifying key pathways or targets for therapeutic intervention.
Education/Academic qualification
Medicine, PhD, University of Melbourne
Apr 1984 → Feb 1988
Pathology, BSc(Hons), University of Melbourne
1983
Biochemistry and Pathology, BSc, University of Melbourne
1979 → 1982
Research area keywords
- Autoimmunity
- Haematopoiesis
- Chronic inflammatory lung disease
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Projects
Dissecting the contribution of IL-17-producing γδ T cells to the pathogenesis of airway diseases
Hibbs, M. & Anderson, G. P.
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/20
Project: Research
G-CSF = granulocyte colony-stimulating factor: G-CSF: a pathogenic effector in chronic obstructive pulmonary disease and its comorbidities
Hibbs, M., Anderson, G. P. & Tsantikos, E.
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/21
Project: Research
Designing superior killers in cancer immunotherapy
Borger, J., Hibbs, M. & Beavis, P.
1/01/19 → 31/12/19
Project: Research
A strategy to treat the common deadly lung disease chronic obstructive pulmonary disease
1/01/17 → 31/12/17
Project: Research
NHMRC equipment grant - BD LSR Fortessa X20 Flow Cytometry system
Tarlinton, D., O'Hehir, R., Cooper, M. E., Peleg, A., Curtis, D., Dickins, R., van Zelm, M., Plebanski, M., Spencer, A., Hibbs, M., Wei, A., Guthridge, M. A. & Thomas, M.
1/12/16 → 31/12/16
Project: Research
Research Output
Engineering of Nebulized Metal–Phenolic Capsules for Controlled Pulmonary Deposition
Ju, Y., Cortez-Jugo, C., Chen, J., Wang, T. Y., Mitchell, A. J., Tsantikos, E., Bertleff-Zieschang, N., Lin, Y. W., Song, J., Cheng, Y., Mettu, S., Rahim, M. A., Pan, S., Yun, G., Hibbs, M. L., Yeo, L. Y., Hagemeyer, C. E. & Caruso, F., 1 Mar 2020, In : Advanced Science. 7, 6, 13 p., 1902650.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization
Eissmann, M. F., Dijkstra, C., Jarnicki, A., Phesse, T., Brunnberg, J., Poh, A. R., Etemadi, N., Tsantikos, E., Thiem, S., Huntington, N. D., Hibbs, M. L., Boussioutas, A., Grimbaldeston, M. A., Buchert, M., O’Donoghue, R. J. J., Masson, F. & Ernst, M., 1 Dec 2019, In : Nature Communications. 10, 1, 16 p., 2735.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
11
Citations
(Scopus)
Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems
Sharma, R., Shultz, S. R., Robinson, M. J., Belli, A., Hibbs, M. L., O'Brien, T. J. & Semple, B. D., Jul 2019, In : Brain, Behavior, and Immunity. 79, p. 63-74 12 p.Research output: Contribution to journal › Review Article › Research › peer-review
6
Citations
(Scopus)
The influence of innate lymphoid cells and unconventional T cells in chronic inflammatory lung disease
Borger, J. G., Lau, M. & Hibbs, M. L., 11 Jul 2019, In : Frontiers in Immunology. 10, JULY, 16 p., 1597.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
1
Citation
(Scopus)
Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease
Tsantikos, E., Lau, M., Castelino, C. M. N., Maxwell, M. J., Passey, S. L., Hansen, M. J., McGregor, N. E., Sims, N. A., Steinfort, D. P., Irving, L. B., Anderson, G. P. & Hibbs, M. L., 1 Jun 2018, In : Journal of Clinical Investigation. 128, 6, p. 2406-2418 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
10
Citations
(Scopus)