Projects per year
Personal profile
Biography
Associate Professor Margaret Hibbs
Department of Immunology - Leukocyte Signalling Laboratory
Margaret Hibbs is an Associate Professor in the Department of Immunology, within the Central Clinical School, and Group leader of the Leukocyte Signalling Laboratory.
The Leukocyte Signaling Laboratory is studying signaling pathways that play a role in immune system development and function. We are primarily interested in what regulates the development of immunity and we are trying to understand the processes that are perturbed when autoimmunity and inflammatory diseases develop. We are also interested in understanding what regulates haematopoiesis or blood cell development, and believe that this will give us a greater understanding of the signals that go awry in the development of blood cell cancers. The lab also has a major interest in understanding the mechanisms underlying chronic inflammatory lung disease and we aim to identifying key pathways or targets for therapeutic intervention.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, PhD, University of Melbourne
Apr 1984 → Feb 1988
Pathology, BSc(Hons), University of Melbourne
1983
Biochemistry and Pathology, BSc, University of Melbourne
1979 → 1982
Research area keywords
- Autoimmunity
- Haematopoiesis
- Chronic inflammatory lung disease
Network
-
Dysregulated lymphatic vasculature in the pathogenesis of bronchopulmonary dysplasia
Hibbs, M., Tsantikos, E., Stacker, S. A., Anderson, G., Malhotra, A., Kumar, B., Wong, N. & Cho, E.
1/01/23 → 31/12/26
Project: Research
-
Novel therapeutic approaches for SLE
Mackay, F., Mackay, C. & Hibbs, M.
1/12/19 → 1/12/23
Project: Research
-
-
Designing superior killers in cancer immunotherapy
Borger, J., Hibbs, M. & Beavis, P. A.
1/01/19 → 31/12/19
Project: Research
-
Apigenin Targets MicroRNA-155, Enhances SHIP-1 Expression, and Augments Anti-Tumor Responses in Pancreatic Cancer
Husain, K., Villalobos-Ayala, K., Laverde, V., Vazquez, O. A., Miller, B., Kazim, S., Blanck, G., Hibbs, M. L., Krystal, G., Elhussin, I., Mori, J., Yates, C. & Ghansah, T., Aug 2022, In: Cancers. 14, 15, 22 p., 3613.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking
Gottschalk, T. A., Hall, P., Tsantikos, E., L’Estrange-Stranieri, E., Hickey, M. J. & Hibbs, M. L., 12 May 2022, In: Frontiers in Immunology. 13, 13 p., 875359.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
β-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping
Bouchery, T., Volpe, B., Doolan, R., Coakley, G., Moyat, M., Esser-von Bieren, J., Wickramasinghe, L. C., Hibbs, M. L., Sotillo, J., Camberis, M., Le Gros, G., Khan, N., Williams, D. & Harris, N. L., Apr 2022, In: Immunology and Cell Biology. 100, 4, p. 223-234 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Advances in Translational Science to Identify New Therapies for Systemic Lupus Erythematosus
Hoi, A., Vincent, F. B. & Hibbs, M. L., 2021, Pathogenesis of Systemic Lupus Erythematosus: Insights from Translational Research. Hoi, A. (ed.). 1st ed. Cham Switzerland: Springer, p. 1-8 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
-
An Experimental Model of Bronchopulmonary Dysplasia Features Long-Term Retinal and Pulmonary Defects but Not Sustained Lung Inflammation
Wickramasinghe, L. C., van Wijngaarden, P., Johnson, C., Tsantikos, E. & Hibbs, M. L., 30 Aug 2021, In: Frontiers in Pediatrics. 9, 13 p., 689699.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus)