Margaret Hibbs

Assoc Professor

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Associate Professor Margaret Hibbs 

Department of Immunology - Leukocyte Signalling Laboratory

Margaret Hibbs is an Associate Professor in the Department of Immunology, within the Central Clinical School, and Group leader of the Leukocyte Signalling Laboratory.

The Leukocyte Signaling Laboratory is studying signaling pathways that play a role in immune system development and function. We are primarily interested in what regulates the development of immunity and we are trying to understand the processes that are perturbed when autoimmunity and inflammatory diseases develop. We are also interested in understanding what regulates haematopoiesis or blood cell development, and believe that this will give us a greater understanding of the signals that go awry in the development of blood cell cancers. The lab also has a major interest in understanding the mechanisms underlying chronic inflammatory lung disease and we aim to identifying key pathways or targets for therapeutic intervention.



  • Autoimmunity
  • Haematopoiesis
  • Chronic inflammatory lung disease

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Projects 2010 2021

Research Output 2004 2017

Csk-binding protein controls red blood cell development via regulation of Lyn tyrosine kinase activity

Plani-Lam, J. H. C., Slavova-Azmanova, N. S., Kucera, N., Louw, A., Satiaputra, J., Singer, P., Lam, K. P., Hibbs, M. L. & Ingley, E. 1 Feb 2017 In : Experimental Hematology. 46, p. 70-82 13 p.

Research output: Contribution to journalArticle

Foxp3+ Tregs are recruited to the retina to repair pathological angiogenesis

Deliyanti, D., Talia, D. M., Zhu, T., Maxwell, M. J., Agrotis, A., Jerome, J. R., Hargreaves, E. M., Gerondakis, S., Hibbs, M. L., Mackay, F. & Wilkinson-Berka, J. L. 1 Dec 2017 In : Nature Communications. 8, 1, 12 p., 748

Research output: Contribution to journalArticle

Open Access

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

Luo, L., Bokil, N. J., Wall, A. A., Kapetanovic, R., Lansdaal, N. M., Marceline, F., Burgess, B. J., Tong, S. J., Guo, Z., Alexandrov, K., Ross, I. L., Hibbs, M. L., Stow, J. L. & Sweet, M. J. 18 Jan 2017 In : Nature Communications. 8, 14 p., 14133

Research output: Contribution to journalArticle

Open Access

The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis

Duan, M., Hibbs, M. L. & Chen, W. 1 Mar 2017 In : Immunology and Cell Biology. 95, 3, p. 225-235 11 p.

Research output: Contribution to journalReview Article

CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs

Duan, M., Steinfort, D. P., Smallwood, D., Hew, M., Chen, W., Ernst, M., Irving, L. B., Anderson, G. P. & Hibbs, M. L. 1 Mar 2016 In : Mucosal Immunology. 9, 2, p. 550-563 14 p.

Research output: Contribution to journalArticle