Accepting PhD Students

PhD projects

Targeting CD39 to improve outcome in models of small vessel thrombosis

20102019

Research output per year

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Personal profile

Biography

Dr Maithili Sashindranath is a Research Fellow and oversees the basic science research in the Vascular Biology Group within the Australian Centre for Blood Diseases (ACBD). The Vascular Biology Research program is headed by Professor Harshal Nandurkar, Director of the ACBD.

Biography

Dr Sashindranath has over 15 years of experience in Neuroscience research and is an expert in the fields of brain injury and stroke. She currently works as a Senior Research Fellow with the Vascular Biology group in the Australian Centre for Blood Diseases, Monash University, where she leads a team of research assistants and PhD students. Her current research interests are focussed on improving outcomes in small vessel thrombosis and ischemic stroke. She previously worked as a Research Fellow at the Molecular Neurotrauma and Haemostasis laboratory in the same department. She has received and been named on grant applications amounting to over 150,000$ and has been involved in securing 4 successful NHMRC grant applications. She has had 22 publications in the last 7 years inclduing 4 as co-senior author.

Dr Sashindranath graduated with a PhD from the University of Melbourne in December 2009 during which she studied seizure induced oxidative stress and kinase signalling processes in epilepsy. She was the recipient of the Melbourne Research Scholarship (2004-2008) as well as the Leslie Eric Paddle scholarship (2006 and 2007) and the RJ Gleghorn scholarship (2007) for PhD studies. Dr Sashindranath completed a BSc Hons degree from the University of Cape Town, South Africa in 2003. 

She is committed to being a role model in the community and visits primary schools to promote interest in STEM, and is particularly focussed on inspiring young girls to pursue STEM careers. She also has a keen interest in supporting women in STEM and is Deputy Chair of the Monash Central Clinical School's Gender Equity and Diversity Committee. 

Research area keywords

  • Inflammation
  • Thrombosis
  • Endothelial biology
  • Microfluidics

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Projects

Research Output

Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

Daglas, M., Draxler, D. F., Ho, H., McCutcheon, F., Galle, A., Au, A. E., Larsson, P., Gregory, J., Alderuccio, F., Sashindranath, M. & Medcalf, R. L., 29 Oct 2019, In : Cell Reports. 29, 5, p. 1178-1191.e6 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

The mode of anesthesia influences outcome in mouse models of arterial thrombosis

Sashindranath, M., Sturgeon, S., French, S. L., Craenmehr, D. D. D., Selan, C., Freddi, S., Johnson, C., Cody, S., Nesbitt, W., Hamilton, J., Cody, S. H., Nesbitt, W., Hamilton, J. & Nandurkar, H., Apr 2019, In : Thrombosis and Haemostasis. 3, 2, p. 197-206 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Tranexamic Acid Influences the Immune Response, but not Bacterial Clearance in a Model of Post-Traumatic Brain Injury Pneumonia

Draxler, D. F., Awad, M. M., Hanafi, G., Daglas, M., Ho, H., Keragala, C., Galle, A., Roquilly, A., Lyras, D., Sashindranath, M. & Medcalf, R. L., 1 Dec 2019, In : Journal of Neurotrauma. 36, 23, p. 3297-3308 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis

Draxler, D. F., Daglas, M., Fernando, A., Hanafi, G., McCutcheon, F., Ho, H., Galle, A., Gregory, J., Larsson, P., Keragala, C., Wright, D. K., Tavancheh, E., Au, A. E., Niego, B., Wilson, K., Plebanski, M., Sashindranath, M. & Medcalf, R. L., Dec 2019, In : Journal of Thrombosis and Haemostasis. 17, 12, p. 2174-2187 14 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Draxler, D. F., Yep, K., Hanafi, G., Winton, A., Daglas, M., Ho, H., Sashindranath, M., Wutzlhofer, L. M., Forbes, A., Goncalves, I., Tran, H. A., Wallace, S., Plebanski, M., Myles, P. S. & Medcalf, R. L., 28 May 2019, In : Blood Advances. 3, 10, p. 1598-1609 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

Prizes

Advancing Women's Research Success Grant

Sashindranath, Maithili (Recipient), 2014

Prize: Prize (including medals and awards)

Early Career Research Publication Prize

Sashindranath, Maithili (Recipient), 2013

Prize: Prize (including medals and awards)

Mouse Specifics Inc Award

Sashindranath, Maithili (Recipient), 2014

Prize: Prize (including medals and awards)

Senior Medical Researcher Staff Prize

Sashindranath, Maithili (Recipient), 2010

Prize: Prize (including medals and awards)

Activities

  • 6 Peer review responsibility
  • 1 Collaboration on community projects

CSIRO STEM Professionals in Schools

Maithili Sashindranath (Advisor)

Feb 2019 → …

Activity: Community Talks, Presentations, Exhibitions and EventsCollaboration on community projects

European Journal of Neuroscience (Journal)

Maithili Sashindranath (Peer reviewer)

2 Apr 201919 Nov 2019

Activity: Publication peer-review and editorial work typesPeer review responsibility

Brain, Behavior, and Immunity (Journal)

Maithili Sashindranath (Peer reviewer)

Jan 2018May 2018

Activity: Publication peer-review and editorial work typesPeer review responsibility

Scientific Reports (Journal)

Maithili Sashindranath (Peer reviewer)

Nov 2017

Activity: Publication peer-review and editorial work typesPeer review responsibility

Behavioural Neurology (Journal)

Maithili Sashindranath (Peer reviewer)

2017

Activity: Publication peer-review and editorial work typesPeer review responsibility