Projects per year
Personal profile
Biography
Dr Luc Furic heads the Prostate Cancer Laboratory at Monash's BDI and he is a Senior Research Fellow in the Department of Anatomy and Developmental Biology.
Dr Furic's current research program focuses on survival signalling in prostate cancer cells and the role it plays in the transition from hormone-sensitive to castrate-resistant prostate cancer. His laboratory uses biochemical and molecular biology approaches to gain a better understanding of the molecular mechanisms responsible for prostate cancer initiation and progression.
Since 2002, he has received multiple scholarships, awards and fellowships from competitive schemes at both national and international levels. These awards include the US Department of Defense Postdoctoral Prostate Cancer training award (2009-2011), the Canadian Cancer Society Postdoctoral Fellowship (2008-2010), the Quebec Health Fund graduate scholarship (2003-2006) and postdoctoral fellowship (2007-2009), the National Science and Engineering Council of Canada graduate scholarship (2004-2006). More recently, he was awarded the ARC DECRA (2012-2015), a Young Investigator Award from the Prostate Cancer Foundation of Australia (2011-2016), a Victorian Cancer Agency Early Career Seed grant (2011-2012), a VCA Mid-Career Fellowship (2017-2020), NHMRC Project grants and VMRAF funding.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biochemistry, PhD, University of Montreal
Award Date: 5 Apr 2007
Research area keywords
- Cancer Biology
- Translation
- Prostate Cancer
- Signalling pathways
Collaborations and top research areas from the last five years
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Developing novel CAR T cell therapy approaches to treat prostate cancer
Taylor, R., Porter, L., Trapani, J., Darcy, P., Neeson, P. J., Risbridger, G., Risbridger, G., Solomon, B. J., Azad, A. & Furic, L.
1/01/22 → 31/12/25
Project: Research
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A novel strategy for targeting castrate-resistant prostate cancer
Risbridger, G., Tilley, W. D., Furic, L., Sandhu, S. K., Azad, A., Selth, L. A. & Lawrence, M.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/18 → 31/12/21
Project: Research
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Codon bias: a hidden layer of translational regulation by estrogens
Furic, L., Larsson, O. & Topisirovic, I.
1/01/18 → 31/12/21
Project: Research
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Novel combination therapies targeting the ribosome to treat prostate cancer
Furic, L., Daly, R., Hannan, R., Risbridger, G., Pearson, R. D. & Sandhu, S. K.
1/05/15 → 30/04/18
Project: Research
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Arginine-rich C9ORF72 ALS proteins stall ribosomes in a manner distinct from a canonical ribosome-associated quality control substrate
Kriachkov, V., Ormsby, A. R., Kusnadi, E. P., McWilliam, H. E. G., Mintern, J. D., Amarasinghe, S. L., Ritchie, M. E., Furic, L. & Hatters, D. M., Jan 2023, In: Journal of Biological Chemistry. 299, 1, 15 p., 102774.Research output: Contribution to journal › Article › Research › peer-review
Open Access12 Citations (Scopus) -
YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells
Bai, Y., Gotz, C., Chincarini, G., Zhao, Z., Slaney, C., Boath, J., Furic, L., Angel, C., Jane, S. M., Phillips, W. A., Stacker, S. A., Farah, C. S. & Darido, C., 22 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1591.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus) -
AlphaBet: Combination of Radium-223 and [177Lu]Lu-PSMA-I&T in men with metastatic castration-resistant prostate cancer (clinical trial protocol)
Kostos, L., Buteau, J. P., Yeung, T., Iulio, J. D., Xie, J., Cardin, A., Chin, K. Y., Emmerson, B., Owen, K. L., Parker, B. S., Fettke, H., Furic, L., Azad, A. A. & Hofman, M. S., 18 Nov 2022, In: Frontiers in Medicine. 9, 13 p., 1059122.Research output: Contribution to journal › Article › Other › peer-review
Open Access27 Citations (Scopus) -
Regulation of gene expression via translational buffering
Kusnadi, E. P., Timpone, C., Topisirovic, I., Larsson, O. & Furic, L., Jan 2022, In: BBA Molecular Cell Research. 1869, 1, 10 p., 119140.Research output: Contribution to journal › Review Article › Research › peer-review
24 Citations (Scopus) -
CX-5461 sensitizes DNA damage repair-proficient castrate-resistant prostate cancer to PARP inhibition
Lawrence, M. G., Porter, L. H., Choo, N., Pook, D., Grummet, J. P., Pezaro, C. J., Sandhu, S., Ramm, S., Luu, J., Bakshi, A., Goode, D. L., Sanij, E., Pearson, R. B., Hannan, R. D., Simpson, K. J., Taylor, R. A., Risbridger, G. P. & Furic, L., Nov 2021, In: Molecular Cancer Therapeutics. 20, 11, p. 2140-2150 11 p.Research output: Contribution to journal › Article › Research › peer-review
13 Citations (Scopus)