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Personal profile

Biography

Dr Luc Furic is a Senior Research Fellow in the Department of Anatomy and Developmental Biology.

My current research program focuses on survival signalling in prostate cancer cells and its role in the transition from hormone-sensitive to castrate-resistant prostate cancer. My laboratory uses biochemical and molecular biology approaches to gain a better understanding of the molecular mechanisms responsible for prostate cancer initiation and progression.

Since 2002, I have received multiple scholarships, awards and fellowships from competitive schemes at both national and international levels. These awards include the US Department of Defense Postdoctoral Prostate Cancer training award (2009-2011), the Canadian Cancer Society Postdoctoral Fellowship (2008-2010), the Quebec Health Fund graduate scholarship (2003-2006) and postdoctoral fellowship (2007-2009), the National Science and Engineering Council of Canada graduate scholarship (2004-2006). More recently, I was awarded the ARC DECRA (2012-2015), a Young Investigator Award from the Prostate Cancer Foundation of Australia (2011-2016) and a Victorian Cancer Agency Early Career Seed grant (2011-2012).

 

Research area keywords

  • Cancer Biology
  • Translation
  • Prostate Cancer
  • Signalling pathways

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Projects

Research Output

A balancing act: PHLPP2 fine tunes AKT activity and MYC stability in prostate cancer

Toivanen, R. & Furic, L., 3 Jun 2019, In : Journal of Cell Biology. 218, 6, p. 1771-1772 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Generally applicable transcriptome-wide analysis of translation using anota2seq

Oertlin, C., Lorent, J., Murie, C., Furic, L., Topisirovic, I. & Larsson, O., 9 Jul 2019, In : Nucleic Acids Research. 47, 12, 15 p., e70.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

MTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans

Puelles, V. G., van der Wolde, J. W., Wanner, N., Scheppach, M. W., Cullen-McEwen, L. A., Bork, T., Lindenmeyer, M. T., Gernhold, L., Wong, M. N., Braun, F., Cohen, C. D., Kett, M. M., Kuppe, C., Kramann, R., Saritas, T., Van Roeyen, C. R., Moeller, M. J., Tribolet, L., Rebello, R., Sun, Y. B. Y. & 13 others, Li, J., Müller-Newen, G., Hughson, M. D., Hoy, W. E., Person, F., Wiech, T., Ricardo, S. D., Kerr, P. G., Denton, K. M., Furic, L., Huber, T. B., Nikolic-Paterson, D. J. & Bertram, J. F., 19 Sep 2019, In : JCI Insight. 4, 18, 18 p., e99271.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer

Watt, M. J., Clark, A. K., Selth, L. A., Haynes, V. R., Lister, N., Rebello, R., Porter, L. H., Niranjan, B., Whitby, S. T., Lo, J., Huang, C., Schittenhelm, R. B., Anderson, K. E., Furic, L., Wijayaratne, P. R., Matzaris, M., Montgomery, M. K., Papargiris, M., Norden, S., Febbraio, M. & 4 others, Risbridger, G. P., Frydenberg, M., Nomura, D. K. & Taylor, R. A., 6 Feb 2019, In : Science Translational Medicine. 11, 478, 12 p., eaau5758.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

Lorent, J., Kusnadi, E. P., van Hoef, V., Rebello, R. J., Leibovitch, M., Ristau, J., Chen, S., Lawrence, M. G., Szkop, K. J., Samreen, B., Balanathan, P., Rapino, F., Close, P., Bukczynska, P., Scharmann, K., Takizawa, I., Risbridger, G. P., Selth, L. A., Leidel, S. A., Lin, Q. & 3 others, Topisirovic, I., Larsson, O. & Furic, L., 2 Dec 2019, In : The EMBO journal. 38, 23, 19 p., e101323.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)