Projects per year
Personal profile
Biography
The Martin group uses a multi-disciplinary approach to answer research questions ranging from Inorganic Chemistry through to Chemical Biology. Our philosophy is that biology raises the questions and chemistry provides the solutions.
Of particular interest is the use of lipid membranes as a biomimetic material to explore activity, structure and function of (i) redox active membrane proteins, including protein assembly in membranes and (ii) peptide-membrane interactions; including anti-microbial peptides (AMP), carrier peptides (eg. Tat), insulin and neurodegenerative peptides that aggregate. We employ a wide range of physicochemical techniques combined with synthetic chemistry, molecular and electronic (redox) considerations in order to target biomedical problems. Thus our research applies novel, innovative and highly cross-disciplinary methodologies to exciting and challenging research problems; strong national and international collaborations are involved.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Network
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Engineering CYP17A1 inhibitors for castrate-resistant prostate cancer
Martin, L. & Bell, S. G.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/21 → 31/12/23
Project: Research
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LVis Plate without QC filters, with cuvette port and 16 spots for low volume measurements
Martin, L. & Bell, S. G.
1/10/21 → 31/12/22
Project: Research
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Magnetometry Facility for Molecular and Nanoscale Materials
Boskovic, C., Wang, L., Mulvaney, P., Jones, C., Fuller, R., Daeneke, T., Abrahams, B. F., Ou, J., Turner, D., Li, D., Martin, L. & Soncini, A.
Australian Research Council (ARC)
4/05/21 → 3/05/22
Project: Research
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Evolution of Steroid Hormones & their role in Castrate Resistant Prostate Cancer
18/12/19 → 1/01/20
Project: Research
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The antibacterial activity of amyloidogenic peptide Uperin 3.5 modulated by membrane composition and amino acid sequence
Piantavigna, S., Martin, L. & Holt, S.
14/10/18 → 22/10/18
Project: Research
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Curvature model for nanoparticle size effects on peptide fibril stability and molecular dynamics simulation data
John, T., Martin, L. L., Risselada, H. J. & Abel, B., Dec 2022, In: Data in Brief. 45, 8 p., 108598.Research output: Contribution to journal › Article › Research › peer-review
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Galvanic replacement of anions in metal-organic semiconductors: a spontaneous redox reaction between TCNQ1− and TCNQF40 (TCNQ = 7,7,8,8-tetracyanoquinodimethane)
Hussain, Z., Ojha, R., La, D. D., Nafady, A., Bhosale, S. V., Martin, L. L., Bond, A. M., Ramanathan, R. & Bansal, V., Dec 2022, In: Materials Today Chemistry. 26, 10 p., 100998.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Mechanistic insights into the size-dependent effects of nanoparticles on inhibiting and accelerating amyloid fibril formation
John, T., Adler, J., Elsner, C., Petzold, J., Krueger, M., Martin, L. L., Huster, D., Risselada, H. J. & Abel, B., 15 Sep 2022, In: Journal of Colloid and Interface Science. 622, p. 804-818 15 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
Oxidation of Thiosulphate using TCNQFn (n=0, 2, 4) Derivatives with a Tuneable Driving Force: Electrochemical and Spectrophotometric Detection of a Protonated Intermediate
Alzubidi, A. E., Bond, A. M. & Martin, L. L., 26 Aug 2022, In: ChemElectroChem. 9, 16, 15 p., e202200538.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Secondary Structure Transitions for a Family of Amyloidogenic, Antimicrobial Uperin 3 Peptides in Contact with Sodium Dodecyl Sulfate
Prasad, A. K., Tiwari, C., Ray, S., Holden, S., Armstrong, D. A., Rosengren, K. J., Rodger, A., Panwar, A. S. & Martin, L. L., Jan 2022, In: ChemPlusChem. 87, 1, 14 p., e202100408.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus)