Projects per year
Personal profile
Biography
The Martin group uses a multi-disciplinary approach to answer research questions ranging from Inorganic Chemistry through to Chemical Biology. Our philosophy is that biology raises the questions and chemistry provides the solutions.
Of particular interest is the use of lipid membranes as a biomimetic material to explore activity, structure and function of (i) redox active membrane proteins, including protein assembly in membranes and (ii) peptide-membrane interactions; including anti-microbial peptides (AMP), carrier peptides (eg. Tat), insulin and neurodegenerative peptides that aggregate. We employ a wide range of physicochemical techniques combined with synthetic chemistry, molecular and electronic (redox) considerations in order to target biomedical problems. Thus our research applies novel, innovative and highly cross-disciplinary methodologies to exciting and challenging research problems; strong national and international collaborations are involved.
Network
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LVis Plate without QC filters, with cuvette port and 16 spots for low volume measurements
Martin, L. & Bell, S. G.
1/10/21 → 31/12/22
Project: Research
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Engineering CYP17A1 inhibitors for castrate-resistant prostate cancer
Martin, L. & Bell, S. G.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/21 → 31/12/23
Project: Research
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Magnetometry Facility for Molecular and Nanoscale Materials
Boskovic, C., Wang, L., Mulvaney, P., Jones, C., Fuller, R., Daeneke, T., Abrahams, B. F., Ou, J., Turner, D., Li, D., Martin, L. & Soncini, A.
Australian Research Council (ARC)
4/05/21 → 3/05/22
Project: Research
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Evolution of Steroid Hormones & their role in Castrate Resistant Prostate Cancer
18/12/19 → 1/01/20
Project: Research
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The antibacterial activity of amyloidogenic peptide Uperin 3.5 modulated by membrane composition and amino acid sequence
Piantavigna, S., Martin, L. & Holt, S.
14/10/18 → 22/10/18
Project: Research
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Enantiomeric selectivity of ruthenium (II) chiral complexes with antitumor activity, in vitro and in vivo
Zhang, W., Sun, Y., Wang, J., Ding, X., Yang, E., Martin, L. L. & Sun, D., Mar 2021, In: Journal of Inorganic Biochemistry. 216, 12 p., 111339.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Electrochemically Directed Synthesis of Cobalt(ii) and Nickel(ii) TCNQF21-/2-Coordination Polymers: Solubility and Substituent Effects in the TCNQF n(n = 0, 1, 2, 4) Series of Complexes
Vo, N. T., Bond, A. M. & Martin, L. L., 1 Sep 2020, In: Australian Journal of Chemistry. 73, 12, p. 1197-1207 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Exploring the role of peptide helical stability in the propensity of uperin 3.x peptides toward beta-aggregation
Ray, S., Holden, S., Prasad, A. K., Martin, L. L. & Panwar, A. S., 24 Dec 2020, In: Journal of Physical Chemistry B. 124, 51, p. 11659-11670 12 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Sequence comparisons of cytochrome P450 aromatases from Australian animals predict differences in enzymatic activity and/or efficiency
Fatima, A., Holien, J. K., Tiwari, C., Parker, M., Rodgers, R. & Martin, L., 26 May 2020, In: Biology of Reproduction. 102, 6, p. 1261-1269 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
Systematic and non-systematic substituent effects gleaned from studies on CuTCNQFn (n = 0, 1, 2, 4): Electrocrystallisation and characterisation of CuTCNQF
Vo, N. T., Bond, A. M. & Martin, L. L., 24 May 2020, In: Inorganica Chimica Acta. 505, 11 p., 119458.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus)