Projects per year
Personal profile
Education/Academic qualification
Medicine, PhD, Regulation of post-translational modifications of the protein kinase LKB1: molecular mechanisms and physiological implications, University of Hong Kong
2 Jan 2007 → 29 Nov 2011
Award Date: 29 Nov 2011
Functional genomics, Master of Research, Myocardial insulin signalling pathway in insulin resistant syndromes in human, rat and mouse, University of York (United Kingdom)
1 Sept 2005 → 2 Dec 2006
Award Date: 17 Mar 2007
Research area keywords
- Cancer Cell Biology
- Functional genomics
- high throughput screening
- circular RNA
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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Mechanistic and functional characterization of the atypical kinase SgK269
Liu, L. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/13 → 27/07/15
Project: Research
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SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss
Xi, X. (Leading Author), Liu, L., Tuano, N., Tailhades, J., Mouradov, D., Steen, J., Sieber, O., Cryle, M., Nguyen-Dumont, T., Segelov, E. & Rosenbluh, J. (Leading Author), 15 Apr 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 15, 12 p., e2409677122.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as a vulnerability in ER-positive breast cancers
Hosseinpour, M. (Leading Author), Xi, X., Liu, L., Malaver-Ortega, L., Perlaza-Jimenez, L., Joo, J. E., York, H. M., Beesley, J., Caldon, C. E., Dugué, P. A., Dowty, J. G., Arumugam, S., Southey, M. C. (Leading Author) & Rosenbluh, J. (Leading Author), Dec 2024, In: Nature Communications. 15, 1, 12 p., 10449.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Systematic loss-of-function screens identify pathway-specific functional circular RNAs
Liu, L., Neve, M., Perlaza-Jimenez, L., Xi, X., Purcell, J., Hawdon, A., Conn, S. J., Zenker, J., Tamayo, P., Goodall, G. J. & Rosenbluh, J. (Leading Author), 2024, In: Nature Cell Biology. 26, p. 1359–1372 13 p.Research output: Contribution to journal › Article › Research › peer-review
5 Link opens in a new tab Citations (Scopus) -
Author Correction: CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies (Genome Biology, (2021), 22, 1, (47), 10.1186/s13059-021-02266-6)
Davies, R. G., Liu, L., Taotao, S., Tuano, N., Chaturvedi, R., Huang, K. K., Itman, C., Mandoli, A., Qamra, A., Hu, C., Powell, D., Daly, R. J., Tan, P. & Rosenbluh, J., 25 Mar 2021, In: Genome Biology. 22, 1, 2 p., 88.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies
Davies, R., Liu, L., Taotao, S., Tuano, N., Chaturvedi, R., Huang, K. K., Itman, C., Mandoli, A., Qamra, A., Hu, C., Powell, D., Daly, R. J., Tan, P. & Rosenbluh, J., 26 Jan 2021, In: Genome Biology. 22, 1, 19 p., 47.Research output: Contribution to journal › Article › Research › peer-review
Open Access23 Link opens in a new tab Citations (Scopus)
Activities
- 1 Contribution to conference
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Systematic identification and characterization of functional variants in CDH1 using scanning mutagenesis ORF and base editor screens
Liu, L. (Organiser)
29 Aug 2023 → 1 Sept 2023Activity: Participating in or organising an event types › Contribution to conference