• 18 Alliance Lane, Room 229, Monash University, Wellington Road

    3800 Clayton


Accepting PhD Students


Research output per year

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Personal profile


Leonie obtained her MSc degree in Molecular Life Sciences with a specialization in Physical Chemistry from Wageningen University & Research (the Netherlands) in 2012. After an industrial traineeship at CSIRO (Clayton, Australia) she continued with her PhD in the Department of Chemical Engineering at The University of Melbourne. She received the 2017 ANSTO, Australian Synchrotron Stephen Wilkins Medal for her PhD thesis entitled “Improving success rates for in meso crystallization using integral membrane proteins and membrane protein mimetics in the bicontinuous cubic phase”. Leonie was a Postdoctoral Research Fellow at ETH Zurich (Switzerland) for several years where she worked on a World food system center research project regarding the preservation of African leafy vegetables and a commercial project on the self-assembly of organic/inorganic colloidal hybrids. She started as a Lecturer and set up the Hybrid Assembly Group at Monash University in October 2019.

Research interests

Leonie uses a unique combination of physical chemistry, chemical engineering, biochemistry and cell biology approaches in her research, and applies it to pharmaceutical and food sciences. The Hybrid Assembly Group focusses on understanding soft material (nano-) structure-property relationships using advanced scattering and microscopy techniques to improve production/processing.

Supervision interests

Research projects, including honours and PhD projects, on self-assembly materials for pharmaceutical applications and structure - property relationships of food materials are available. 

Education/Academic qualification

Chemical Engineering, PhD, University of Melbourne

3 Jun 20133 Dec 2016

Award Date: 9 Dec 2017

Research area keywords

  • Self-assembly
  • Bicontinuous cubic phases
  • Vesicles
  • Proteins, peptides and amino acids
  • Lipid bilayers
  • Food Structure
  • Nanostructured materials
  • Pharmaceuticals
  • In meso crystallisation
  • Membrane proteins
  • Small Angle X-Ray Scattering
  • Small Angle Neutron Scattering
  • Protein structure

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Research Output

Drying of African leafy vegetables for their effective preservation: the difference in moisture sorption isotherms explained by their microstructure

van 't Hag, L., Danthe, J., Handschin, S., Mutuli, G. P., Mbuge, D. & Mezzenga, R., 1 Jan 2020, In : Food & Function. 11, 1, p. 955-964 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Light gold: a colloidal approach using latex templates

van 't Hag, L., Handschin, S., Gschwend, P. M. & Mezzenga, R., 26 Feb 2020, In : Advanced Functional Materials. 30, 9, 9 p., 1908458.

Research output: Contribution to journalArticleResearchpeer-review

Application of gold nanoparticles embedded in the amyloids fibrils as enhancers in the laser induced breakdown spectroscopy for the metal quantification in microdroplets

Dell'Aglio, M., Salajková, Z., Mallardi, A., Mezzenga, R., van't Hag, L., Cioffi, N., Palazzo, G. & De Giacomo, A., May 2019, In : Spectrochimica Acta, Part B: Atomic Spectroscopy. 155, p. 115-122 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Protein-eye view of the in meso crystallization mechanism

van 't Hag, L., de Campo, L., Tran, N., Sokolova, A., Trenker, R., Call, M. E., Call, M. J., Garvey, C. J., Leung, A. E., Darwish, T. A., Krause-Heuer, A., Knott, R., Meikle, T. G., Drummond, C. J., Mezzenga, R. & Conn, C. E., 25 Jun 2019, In : Langmuir. 35, 25, p. 8344-8356 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Direct demonstration of lipid phosphorylation in the lipid bilayer of the biomimetic bicontinuous cubic phase using the confined enzyme lipid A phosphoethanolamine transferase

van 't Hag, L., Anandan, A., Seabrook, S. A., Gras, S. L., Drummond, C. J., Vrielink, A. & Conn, C. E., 21 Feb 2017, In : Soft Matter. 13, 7, p. 1493-1504 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)