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Personal profile

Biography

Biography

I have always been fascinated by how microbial pathogens subvert the host immune defence mechanisms and establish persistent infection. In 2015, I graduated with a doctoral degree from the University of Queensland Diamantina Institute. My current postdoctoral research focuses on understanding how the bacterium Helicobacter pylori modulates the host innate immune system to cause gastric chronic inflammation, a precursor to gastric cancer.

Keywords

  • Helicobacter Pylori
  • Gastric inflammation
  • Gastric (Stomach) Cancer
  • Innate Immunity

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Research Output 2013 2018

  • 6 Article
  • 3 Review Article
  • 1 Chapter (Book)

Isolation of mouse primary gastric epithelial cells to investigate the mechanisms of Helicobacter pylori associated disease

Tran, L. S. & Ferrero, R. L., 11 Jan 2018, Inflammation and Cancer. Humana Press, p. 119-126 8 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase-5 in human monocytes

Bitto, N. J., Baker, P. J., Dowling, J. K., Wray-McCann, G., De Paoli, A., Tran, L. S., Leung, P. L., Stacey, K. J., Mansell, A., Masters, S. L. & Ferrero, R. L., Nov 2018, In : Immunology and Cell Biology. 96, 10, p. 1120-1130 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Mouse Models Of Helicobacter Infection And Gastric Pathologies

D'Costa, K., Chonwerawong, M., Tran, L. S. & Ferrero, R. L., 18 Oct 2018, In : Journal of Visualized Experiments. 2018, 140, 9 p., e56985.

Research output: Contribution to journalReview ArticleOtherpeer-review

NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells

Tran, L. S., Tran, D., De Paoli, A., D'Costa, K., Creed, S. J., Ng, G. Z., Le, L., Sutton, P., Silke, J., Nachbur, U. & Ferrero, R. L., 1 May 2018, In : Cellular Microbiology. 20, 5, 12 p., e12826.

Research output: Contribution to journalArticleResearchpeer-review

Posttranslational modification as a critical determinant of cytoplasmic innate immune recognition

Baker, P. J., De Nardo, D., Moghaddas, F., Tran, L. S., Bachem, A., Nguyen, T., Hayman, T., Tye, H., Vince, J. E., Bedoui, S., Ferrero, R. L. & Masters, S. L., 14 Jun 2017, In : Physiological Reviews. 97, 3, p. 1165-1209 45 p.

Research output: Contribution to journalReview ArticleResearchpeer-review