Projects per year
Personal profile
Biography
Senior Lecturer and Group Leader
Drug Discovery Biology
Monsh Institute of Pharmaceutical Sciences
Faculty of Pharmacy and Pharmaceutical Sciences
Monash University
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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Efficient and Effective Modelling of Protein Structure with Dynamics
Webb, G. (Primary Chief Investigator (PCI)), May, L. (Chief Investigator (CI)) & Whisstock, J. (Chief Investigator (CI))
1/07/25 → 30/06/26
Project: Research
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Adenosine A1 receptor negative allosteric modulators as novel pharmacological interventions for heart failure.
TN Nguyen, A. (Primary Chief Investigator (PCI)) & May, L. (Chief Investigator (CI))
10/01/25 → 31/12/25
Project: Research
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Advancing Preclinical Development of Novel GPCR-targeted Therapeutics for Heart Failure
Ritchie, R. (Primary Chief Investigator (PCI)), Figtree, G. A. (Chief Investigator (CI)), Qin, C. H. (Chief Investigator (CI)), May, L. (Chief Investigator (CI)), Nicholls, S. (Chief Investigator (CI)), Taylor, A. (Chief Investigator (CI)), Yang, J. Y. H. (Chief Investigator (CI)), Shackleford, D. (Chief Investigator (CI)), Schiattarella, G. (Chief Investigator (CI)), Pinto, A. (Chief Investigator (CI)), Drummond, G. (Chief Investigator (CI)), Horowitz, J. D. (Chief Investigator (CI)), Bubb, K. (Chief Investigator (CI)), Vecchio, L. (Associate Investigator (AI)), Nelson, A. (Associate Investigator (AI)), Kirkpatrick, C. (Associate Investigator (AI)), McDonald, C. (Associate Investigator (AI)), Febbraio, M. (Associate Investigator (AI)), Vinh, A. (Associate Investigator (AI)), Odiba, J. (Associate Investigator (AI)), Brown, H. (Associate Investigator (AI)) & Stupple, P. (Chief Investigator (CI))
1/02/23 → 31/07/26
Project: Research
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Development of a New Class of Formyl Peptide Receptor 1 (FPR1) Biased Agonists for the Treatment of Myocardial Infarction
Ritchie, R. (Primary Chief Investigator (PCI)), Stupple, P. (Chief Investigator (CI)), Qin, C. H. (Chief Investigator (CI)), May, L. (Chief Investigator (CI)), Vecchio, L. (Chief Investigator (CI)), Figtree, G. A. (Chief Investigator (CI)), Shackleford, D. (Chief Investigator (CI)), Chong, J. J. H. (Chief Investigator (CI)), Charman, S. (Associate Investigator (AI)) & McDonald, C. (Associate Investigator (AI))
1/01/23 → 31/12/25
Project: Research
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Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Kwan, P. (Primary Chief Investigator (PCI)), May, L. (Chief Investigator (CI)), Rollo, B. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Howden, S. (Chief Investigator (CI)), Christopoulos, A. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)), Scammells, P. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), Elliott, D. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Langmead, C. (Chief Investigator (CI)), Antonic-Baker, A. (Chief Investigator (CI)), Sumer, H. (Chief Investigator (CI)), Javaid, S. (Associate Investigator (AI)) & Gu, J. (Chief Investigator (CI))
1/06/22 → 31/05/27
Project: Research
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Large language models for scientific discovery in molecular property prediction
Zheng, Y., Koh, H. Y., Ju, J., Nguyen, A. T. N., May, L. T., Webb, G. I. & Pan, S., Mar 2025, In: Nature Machine Intelligence. 7, 3, p. 437-447 23 p.Research output: Contribution to journal › Article › Research › peer-review
27 Citations (Scopus) -
Molecular basis of ligand binding and receptor activation at the human A3 adenosine receptor
Zhang, L., Mobbs, J. I., Bennetts, F. M., Venugopal, H., Nguyen, A. T. N., Christopoulos, A., van der Es, D., Heitman, L. H., May, L. T., Glukhova, A. & Thal, D. M., Dec 2025, In: Nature Communications. 16, 1, 19 p., 7674.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Structure-based discovery of positive allosteric modulators of the A1 adenosine receptor
Nguyen, A. T. N., Panel, N., Vo, D. D., Thai, B. S., Chia, L. Y., Lu, C. S., Hellyer, S. D., Langiu, M., Jörg, M., Gregory, K. J., Kihlberg, J., White, P. J., Scammells, P. J., Christopoulos, A., Carlsson, J. & May, L. T., 15 Jul 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 28, 10 p., e2421687122.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Biased receptor signalling and intracellular trafficking profiles of structurally distinct formylpeptide receptor 2 agonists
Peng, C., Vecchio, E. A., Nguyen, A. T. N., De Seram, M., Tang, R., Keov, P., Woodman, O. L., Chen, Y. C., Baell, J., May, L. T., Zhao, P., Ritchie, R. H. & Qin, C. X., Nov 2024, In: British Journal of Pharmacology. 181, 22, p. 4677-4692 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Development of Putative Bivalent Dicovalent Ligands for the Adenosine A1 Receptor
Payne, C. M., Baltos, J. A., Langiu, M., Sinh Lu, C., Tyndall, J. D. A., Gregory, K. J., May, L. T. & Vernall, A. J., 1 Oct 2024, In: ChemBioChem. 25, 19, 10 p., e202400242.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus)
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npj Drug Discovery (Journal)
May, L. (Editorial board member)
13 Jun 2024 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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British Journal of Pharmacology (Journal)
May, L. (Guest editor)
2024Activity: Publication peer-review and editorial work types › Editorial responsibility
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NHMRC Idea's Grant Review Panel (Event)
May, L. (Peer reviewer)
2024 → …Activity: Publication peer-review and editorial work types › Peer review responsibility
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Journal of Pharmacology and Experimental Therapeutics (Journal)
May, L. (Editorial board member)
23 Nov 2022 → 1 Nov 2025Activity: Publication peer-review and editorial work types › Editorial responsibility
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Purinergic Signalling (Journal)
May, L. (Associate editor)
Oct 2022 → …Activity: Publication peer-review and editorial work types › Editorial responsibility