Projects per year
Personal profile
Biography
Position
Heart Foundation Future Leaders Fellow
Drug Discovery Biology
Monsh Institute of Pharmaceutical Sciences
Faculty of Pharmacy and Pharmaceutical Sciences
Monash University
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2008 2022
Adenosine Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease
May, L. T., White, P. J. & Kompa, A.
1/01/18 → 31/12/20
Project: Research
G Protein-Coupled Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease
1/01/18 → 30/06/22
Project: Research
Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions
Christopoulos, A., May, L. T., Imlach, W. L., Hill, S. & Scott, D.
1/01/18 → 31/12/22
Project: Research
Understanding mechanisms of allostery and biased agonism at the adenosine A1 receptor
Christopoulos, A., May, L. T., Scammells, P. J. & Scott, D.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/17
Project: Research
Research Output 2003 2018
A Structure-Activity Relationship Study of Bitopic N 6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists
Aurelio, L., Baltos, J. A., Ford, L., Nguyen, A. T. N., Jörg, M., Devine, S. M., Valant, C., White, P. J., Christopoulos, A., May, L. T. & Scammells, P. J., 8 Mar 2018, In : Journal of Medicinal Chemistry. 61, 5, p. 2087-2103 17 p.Research output: Contribution to journal › Article › Research › peer-review
Characterisation of endogenous A2A and A2B receptor-mediated cyclic AMP responses in HEK 293 cells using the GloSensor™ biosensor: Evidence for an allosteric mechanism of action for the A2B-selective antagonist PSB 603
Goulding, J., May, L. T. & Hill, S. J., 1 Jan 2018, In : Biochemical Pharmacology. 147, p. 55-66 12 p.Research output: Contribution to journal › Article › Research › peer-review
Correspondence: Reply to 'Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury'
Qin, C. X., May, L. T., Sexton, P. M., DeBono, A. J., Baell, J. B., Christopoulos, A. & Ritchie, R. H., 1 Dec 2018, In : Nature Communications. 9, 1, 4 p., 530.Research output: Contribution to journal › Letter › Other › peer-review
Open Access
File
Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination
Liang, Y-L., Zhao, P., Draper-Joyce, C. J., Baltos, J-A., Glukhova, A., Truong, T. T., May, L. T., Christopoulos, A., Wootten, D., Sexton, P. & Furness, S., 26 Jul 2018, (Accepted/In press) In : ACS Pharmacology and Translational Sciences. 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor
Korczynska, M., Clark, M. J., Valant, C., Xu, J., Moo, E. V., Albold, S., Weiss, D. R., Torosyan, H., Huang, W., Kruse, A. C., Lyda, B. R., May, L. T., Baltos, J. A., Sexton, P. M., Kobilka, B. K., Christopoulos, A., Shoichet, B. K. & Sunahara, R. K., 6 Mar 2018, In : Proceedings of the National Academy of Sciences. 115, 10, p. E2419-E2428 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File