Projects per year
Personal profile
Biography
Position
Heart Foundation Future Leaders Fellow
Drug Discovery Biology
Monsh Institute of Pharmaceutical Sciences
Faculty of Pharmacy and Pharmaceutical Sciences
Monash University
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2008 2022
Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions
Christopoulos, A., May, L. T., Imlach, W. L., Hill, S. & Scott, D.
1/01/18 → 31/12/22
Project: Research
Adenosine Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease
May, L. T., White, P. J. & Kompa, A. R.
1/01/18 → 31/12/20
Project: Research
G Protein-Coupled Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease
1/01/18 → 31/12/21
Project: Research
Understanding mechanisms of allostery and biased agonism at the adenosine A1 receptor
Christopoulos, A., May, L. T., Scammells, P. J. & Scott, D.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/17
Project: Research
Research Output 2003 2018
Correspondence: Reply to 'Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury'
Qin, C. X., May, L. T., Sexton, P. M., DeBono, A. J., Baell, J. B., Christopoulos, A. & Ritchie, R. H. 1 Dec 2018 In : Nature Communications. 9, 1, 4 p., 530Research output: Contribution to journal › Letter
Open Access
File
A kinetic view of GPCR allostery and biased agonism
Lane, J. R., May, L. T., Parton, R. G., Sexton, P. M. & Christopoulos, A. 18 Aug 2017 In : Nature Chemical Biology. 13, 9, p. 929-937 9 p.Research output: Contribution to journal › Review Article
Open Access
File
Capadenoson, a clinically trialed partial adenosine A1 receptor agonist, can stimulate adenosine A2B receptor biased agonism
Baltos, J-A., Vecchio, E. A., Harris, M. A., Qin, C. X., Ritchie, R. H., Christopoulos, A., White, P. J. & May, L. T. 1 Jul 2017 In : Biochemical Pharmacology. 135, p. 79–89 11 p.Research output: Contribution to journal › Article
Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice
Qin, C. X., May, L. T., Li, R., Cao, N., Rosli, S., Deo, M., Alexander, A. E., Horlock, D., Bourke, J. E., Yang, Y. H., Stewart, A. G., Kaye, D. M., Du, X. J., Sexton, P. M., Christopoulos, A., Gao, X. M. & Ritchie, R. H. 7 Feb 2017 In : Nature Communications. 8, 13 p., 14232Research output: Contribution to journal › Article
Open Access
File
Structure of the adenosine A1 receptor reveals the basis for subtype selectivity
Glukhova, A., Thal, D. M., Nguyen, A. T., Vecchio, L., Jorg, M., Scammells, P. J., May, L. T., Sexton, P. M. & Christopoulos, A. 23 Feb 2017 In : Cell. 168, 5, p. 867-877.e13Research output: Contribution to journal › Article