Projects per year
Personal profile
Biography
Prof Kim Jacobson (publishing as Kim Good-Jacobson) is a Bellberry-Viertel Senior Medical Research Fellow who studies the formation of immunity. Human health and longevity is dependent on the ability of the immune system to clear the multitude of different foreign pathogens encountered over the life of the host. Her research studies the ability of the immune system to clear pathogens and form immunity through production of B cell memory and antibody, exemplified by her recent work published in Nature Immunology (2022) and Cell Reports (2020).
Kim Good-Jacobson investigates chromatin and transcriptional modifications underlying diversification and selection of B cell fates during the formation of immunity. She completed her PhD at the Centenary and Garvan Institutes in 2007. She was awarded an Arthritis Australia AFA-ARA Heald Fellowship, followed by a CJ Martin Fellowship from the NHMRC to undertake postdoctoral training at Yale University, where she revealed a novel role for the inhibitory receptor PD-1 in humoral responses. She returned to Australia in 2010 and has since made key insights into how histone modifications regulate B cell memory, and the essential requirement for specific molecular factors in the establishment of long-lived humoral immunity in health and chronic disease.
She served as Treasurer for the Australian and New Zealand Society of Immunology and has written for The Conversation. She has also been the recipient of funding from the Cancer Institute NSW and Leukaemia Foundation of Australia.
Related Links:
- B Cells, Antibody, Memory Laboratory
- https://www.monash.edu/discovery-institute/jacobson-lab
- The Conversation: How HIV's evasion tactics could help fight the flu
- https://theconversation.com/how-hivs-evasion-tactics-could-help-fight-the-flu-69278
- The Conversation: Explainer: How viruses can fool the immune system
- https://theconversation.com/explainer-how-viruses-can-fool-the-immune-system-43707
- The Conversation: Six Steps to Fairer Funding for Female Scientists
- https://theconversation.com/six-steps-to-fairer-funding-for-female-scientists-16895
Research interests
Supervision interests
Current graduate students (primary supervisor):
Liam Kealy
Jack Polmear
Clarissa Chakma
Completed students (primary supervisor):
Lucy Cooper
Yan Zhang
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Immunology
- Infection
- B cells
- Immunity
- Immune memory
- Antibody
Network
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Defining SARS-CoV-2 immune maintenance in the Australian population
Smith, C., Gras, S., Short, K. R., Jacobson, K., Hartel, G. F., Barrett, H. & Kitchener, S.
Department of Health and Aged Care (Australia)
1/11/20 → 1/11/22
Project: Research
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Defining the features of atypical T cell responses in Human Immunodeficiency Virus (HIV) controllers
Gras, S., D'Orsogna, L. J., Chakrabarti, L., Lewin, S., Grant, E., Jacobson, K. & Mackay, L. K.
1/01/23 → 31/12/26
Project: Research
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Epigenetic regulation of humoral immune responses.
Jacobson, K. & Di Pietro, A.
1/09/18 → 31/08/19
Project: Research
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Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection
Di Pietro, A., Polmear, J., Cooper, L., Damelang, T., Hussain, T., Hailes, L., O’Donnell, K., Udupa, V., Mi, T., Preston, S., Shtewe, A., Hershberg, U., Turner, S. J., La Gruta, N. L., Chung, A. W., Tarlinton, D. M., Scharer, C. D. & Good-Jacobson, K. L., Jan 2022, In: Nature Immunology. 23, 1, p. 86-98 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses
Kealy, L., Di Pietro, A., Hailes, L., Scheer, S., Dalit, L., Groom, J. R., Zaph, C. & Good-Jacobson, K. L., 15 Dec 2020, In: Cell Reports. 33, 11, 16 p., 108504.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus) -
Immunology at Monash University, Melbourne: celebrating 60 years of the Department of Immunology
Good-Jacobson, K. L., Apr 2023, In: Immunology and Cell Biology. 101, 4, p. 302-304 3 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
Antibody glycosylation directs innate and adaptive immune collaboration
Polmear, J. & Good-Jacobson, K. L., Feb 2022, In: Current Opinion in Immunology. 74, p. 125-132 8 p.Research output: Contribution to journal › Review Article › Research › peer-review
3 Citations (Scopus) -
Editorial overview: Collaboration in the immune system
Good-Jacobson, K. L. & Groom, J. R., Apr 2022, In: Current Opinion in Immunology. 75, 4 p., 102170.Research output: Contribution to journal › Editorial › Other › peer-review
Prizes
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Victorian Young Tall Poppy Science Award
Jacobson, Kim (Recipient), 2016
Prize: Prize (including medals and awards)
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Monash University Vice-Chancellor’s Diversity and Inclusion Award
Jacobson, Kim (Recipient), 2017
Prize: Prize (including medals and awards)
Activities
- 4 Editorial responsibility
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Immunology and Cell Biology (Journal)
Kim Jacobson (Editorial board member)
2022 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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Journal of Immunology (Journal)
Kim Jacobson (Section Editor) (Editorial board member)
2021 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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Journal of Immunology (Journal)
Kim Jacobson (Associate editor)
2016 → 2021Activity: Publication peer-review and editorial work types › Editorial responsibility
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Frontiers in Immunology (Journal)
Kim Jacobson (Editorial board member)
2016 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
Press/Media
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Scientists find tiny part in body that may be key to how vaccines work
22/08/18
1 Media contribution
Press/Media: Expert Comment
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Scientists unlock new secrets of disease-battling immune cells
27/09/16
1 Media contribution
Press/Media: Expert Comment
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Comment: Six steps to fairer funding for female scientists
25/10/13
1 Media contribution
Press/Media: Expert Comment