• 15 Innovation Walk, Building 75

    3800 Clayton

20062024
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Personal profile

Biography

Dr. Kim Jacobson (publishing as Kim Good-Jacobson) studies the formation of immunity. Human health and longevity is dependent on the ability of the immune system to clear the multitude of different foreign pathogens encountered over the life of the host. Her research studies the ability of the immune system to clear pathogens and form immunity through production of B cell memory.

Dr. Kim Good-Jacobson investigates chromatin and transcriptional modifications underlying diversification and selection of B cell fates during the formation of immunity. Dr. Jacobson completed her PhD at the Centenary and Garvan Institutes in 2007. She was awarded an Arthritis Australia AFA-ARA Heald Fellowship, followed by a CJ Martin Fellowship from the NHMRC to undertake postdoctoral training at Yale University, where she revealed a novel role for the inhibitory receptor PD-1 in humoral responses. She returned to Australia in 2010 and has since made key insights into how histone modifications regulate B cell memory, and the essential requirement for the oncogene c-Myb in the establishment of long-lived humoral immunity. Dr. Jacobson has recently relocated to Monash University to establish her own laboratory, focusing on immune memory regulation in health and chronic disease. She currently serves as Deputy Treasurer for ASI and has written for The Conversation. Dr. Jacobson has also been the recipient of funding from the Cancer Institute NSW and Leukaemia Foundation of Australia.

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Research interests

Previous grants awarded:
2012-2014: NHMRC Project Grant (CIA)
"Epigenetic mechanisms that regulate B cell differentiation and memory B cell persistence to provide long-term protection".
2013: Leukaemia Foundation grant-in-aid (CIA).
"Regulation of B cell survival and migration by the oncogene c-Myb."

Supervision interests

Current graduate student:

Lucy Cooper - Master of Biomedical Science Preliminary - Role of transcription factors in regulating antibody responses to infection

Current honours student:

Rohia Farighi - Bachelor of Science (Honours) - Epigenetic regulation of B cell responses

Previous honours student:

Callisthenis Yiannis - Bachelor of Biomedical Science (Honours) - Epigenetic regulation of antibody responses

Keywords

  • Immunology
  • Infection
  • B cells
  • Immunity
  • Immune memory
  • Antibody

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2024

Research Output 2006 2019

B cells turn on, tune in with LSD1

Good-Jacobson, K., 1 Jan 2019, In : Nature Immunology. 20, 1, p. 3-5 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Type I interferon induces CXCL13 to support ectopic germinal center formation

Denton, A. E., Innocentin, S., Carr, E. J., Bradford, B. M., Lafouresse, F., Mabbott, N. A., Mörbe, U., Ludewig, B., Groom, J. R., Good-Jacobson, K. L. & Linterman, M. A., 4 Mar 2019, In : The Journal of experimental medicine. 216, 3, p. 621-637 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses

Cooper, L., Hailes, L., Sheikh, A., Zaph, C., Belz, G. T., Groom, J. R. & Good-Jacobson, K. L., 6 Dec 2018, In : PLoS ONE. 13, 12, 11 p., e0208343.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Disrupting the code: Epigenetic dysregulation of lymphocyte function during infectious disease and lymphoma development

Di Pietro, A. & Good-Jacobson, K. L., 15 Aug 2018, In : Journal of Immunology. 201, 4, p. 1109-1118 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Strength in diversity: Phenotypic, functional, and molecular heterogeneity within the memory B cell repertoire

Good-Jacobson, K. L., 1 Jul 2018, In : Immunological Reviews. 284, 1, p. 67-78 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Prizes

Victorian Young Tall Poppy Science Award

Kim Jacobson (Recipient), 2016

Prize: Prize (including medals and awards)

Activities 2016 2016

  • 2 Editorial responsibility

Journal of Immunology (Journal)

Kim Jacobson (Associate editor)
20162018

Activity: Publication peer-review and editorial work typesEditorial responsibility

Frontiers in Immunology (Journal)

Kim Jacobson (Editorial board member)
2016 → …

Activity: Publication peer-review and editorial work typesEditorial responsibility