• 15 Innovation Walk, Building 75

    3800 Clayton

20062024

Research output per year

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Personal profile

Biography

A/Prof Kim Jacobson (publishing as Kim Good-Jacobson) is a Bellberry-Viertel Senior Medical Research Fellow who studies the formation of immunity. Human health and longevity is dependent on the ability of the immune system to clear the multitude of different foreign pathogens encountered over the life of the host. Her research studies the ability of the immune system to clear pathogens and form immunity through production of B cell memory.

A/Prof Kim Good-Jacobson investigates chromatin and transcriptional modifications underlying diversification and selection of B cell fates during the formation of immunity. A/Prof Jacobson completed her PhD at the Centenary and Garvan Institutes in 2007. She was awarded an Arthritis Australia AFA-ARA Heald Fellowship, followed by a CJ Martin Fellowship from the NHMRC to undertake postdoctoral training at Yale University, where she revealed a novel role for the inhibitory receptor PD-1 in humoral responses. She returned to Australia in 2010 and has since made key insights into how histone modifications regulate B cell memory, and the essential requirement for the oncogene c-Myb in the establishment of long-lived humoral immunity. A/Prof Jacobson has recently relocated to Monash University to establish her own laboratory, focusing on immune memory regulation in health and chronic disease. She served as Treasurer for the Australian and New Zealand Society of Immunology and has written for The Conversation. A/Prof Jacobson has also been the recipient of funding from the Cancer Institute NSW and Leukaemia Foundation of Australia.

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Research interests

Previous grants awarded:
2012-2014: NHMRC Project Grant (CIA)
"Epigenetic mechanisms that regulate B cell differentiation and memory B cell persistence to provide long-term protection".
2013: Leukaemia Foundation grant-in-aid (CIA).
"Regulation of B cell survival and migration by the oncogene c-Myb."

Supervision interests

Current graduate students:

Lucy Cooper

Yan Zhang

Liam Kealy 

Research area keywords

  • Immunology
  • Infection
  • B cells
  • Immunity
  • Immune memory
  • Antibody

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects

Research Output

B Cells Hit a Class Ceiling in the Germinal Center

Cooper, L. & Good-Jacobson, K. L., 20 Aug 2019, In : Immunity. 51, 2, p. 206-208 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

B cells turn on, tune in with LSD1

Good-Jacobson, K., 1 Jan 2019, In : Nature Immunology. 20, 1, p. 3-5 3 p.

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection

Sheikh, A. A., Cooper, L., Feng, M., Souza-Fonseca-Guimaraes, F., Lafouresse, F., Duckworth, B. C., Huntington, N. D., Moon, J. J., Pellegrini, M., Nutt, S. L., Belz, G. T., Good-Jacobson, K. L. & Groom, J. R., 13 Aug 2019, In : Cell Reports. 28, 7, p. 1758-1772 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Epigenetic regulation of B cell fate and function during an immune response

Zhang, Y. & Good-Jacobson, K. L., 1 Mar 2019, In : Immunological Reviews. 288, 1, p. 75-84 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria

Ly, A., Liao, Y., Pietrzak, H., Ioannidis, L. J., Sidwell, T., Gloury, R., Doerflinger, M., Triglia, T., Qin, R. Z., Groom, J. R., Belz, G. T., Good-Jacobson, K. L., Shi, W., Kallies, A. & Hansen, D. S., 19 Nov 2019, In : Cell Reports. 29, 8, p. 2257-2269 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Prizes

Victorian Young Tall Poppy Science Award

Kim Jacobson (Recipient), 2016

Prize: Prize (including medals and awards)

Activities

  • 2 Editorial responsibility

Frontiers in Immunology (Journal)

Kim Jacobson (Editorial board member)
2016 → …

Activity: Publication peer-review and editorial work typesEditorial responsibility

Journal of Immunology (Journal)

Kim Jacobson (Associate editor)
20162018

Activity: Publication peer-review and editorial work typesEditorial responsibility

Press / Media

Scientists find tiny part in body that may be key to how vaccines work

Kim Jacobson

22/08/18

1 Media contribution

Press/Media: Expert Comment

Scientists unlock new secrets of disease-battling immune cells

Kim Jacobson

27/09/16

1 Media contribution

Press/Media: Expert Comment

Comment: Six steps to fairer funding for female scientists

Kim Jacobson

25/10/13

1 Media contribution

Press/Media: Expert Comment