Projects per year
Personal profile
Biography
A/Prof Kim Jacobson (publishing as Kim Good-Jacobson) is a Bellberry-Viertel Senior Medical Research Fellow who studies the formation of immunity. Human health and longevity is dependent on the ability of the immune system to clear the multitude of different foreign pathogens encountered over the life of the host. Her research studies the ability of the immune system to clear pathogens and form immunity through production of B cell memory.
A/Prof Kim Good-Jacobson investigates chromatin and transcriptional modifications underlying diversification and selection of B cell fates during the formation of immunity. A/Prof Jacobson completed her PhD at the Centenary and Garvan Institutes in 2007. She was awarded an Arthritis Australia AFA-ARA Heald Fellowship, followed by a CJ Martin Fellowship from the NHMRC to undertake postdoctoral training at Yale University, where she revealed a novel role for the inhibitory receptor PD-1 in humoral responses. She returned to Australia in 2010 and has since made key insights into how histone modifications regulate B cell memory, and the essential requirement for the oncogene c-Myb in the establishment of long-lived humoral immunity. A/Prof Jacobson has recently relocated to Monash University to establish her own laboratory, focusing on immune memory regulation in health and chronic disease. She served as Treasurer for the Australian and New Zealand Society of Immunology and has written for The Conversation. A/Prof Jacobson has also been the recipient of funding from the Cancer Institute NSW and Leukaemia Foundation of Australia.
Related Links:
- B Cells and Antibody Memory Laboratory
- https://www.monash.edu/discovery-institute/jacobson-lab
- The Conversation: How HIV's evasion tactics could help fight the flu
- https://theconversation.com/how-hivs-evasion-tactics-could-help-fight-the-flu-69278
- The Conversation: Explainer: How viruses can fool the immune system
- https://theconversation.com/explainer-how-viruses-can-fool-the-immune-system-43707
- The Conversation: Six Steps to Fairer Funding for Female Scientists
- https://theconversation.com/six-steps-to-fairer-funding-for-female-scientists-16895
Research interests
Supervision interests
Current graduate students:
Lucy Cooper
Yan Zhang
Liam Kealy
Research area keywords
- Immunology
- Infection
- B cells
- Immunity
- Immune memory
- Antibody
Network
Projects
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Defining SARS-CoV-2 immune maintenance in the Australian population
Smith, C., Gras, S., Short, K. R., Jacobson, K., Hartel, G. F., Barrett, H. & Kitchener, S.
1/11/20 → 1/11/22
Project: Research
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Multiple paths of TFH differentiation and their impact on B cell protection against infection
Groom, J. R., Jacobson, K. & Shi, W.
1/01/18 → 31/12/21
Project: Research
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How do cross-reactive memory B cells affect influenza vaccine titers?
Fox, A., Barr, I., Jacobson, K., Wertheim, H., Smith, D. J., Boyd, S. & Mai, L.
1/01/16 → 31/12/16
Project: Research
Research output
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Dysregulation of humoral immunity in chronic infection
Cooper, L. & Good-Jacobson, K. L., Jul 2020, In : Immunology and Cell Biology. 98, 6, p. 456-466 11 p.Research output: Contribution to journal › Review Article › Research › peer-review
3 Citations (Scopus) -
Hhex drives B cells down memory lane
Good-Jacobson, K. L. & Groom, J. R., Sep 2020, In : Nature Immunology. 21, p. 968-969 2 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open AccessFile -
Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality
Quinn, K. M., Hussain, T., Kraus, F., Formosa, L. E., Lam, W. K., Dagley, M. J., Saunders, E. C., Assmus, L. M., Wynne-Jones, E., Loh, L., van de Sandt, C. E., Cooper, L., Good-Jacobson, K. L., Kedzierska, K., Mackay, L. K., McConville, M. J., Ramm, G., Ryan, M. T. & La Gruta, N. L., 5 Jun 2020, In : Nature Communications. 11, 1, 13 p., 2857.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile4 Citations (Scopus) -
Publisher Correction: Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality (Nature Communications, (2020), 11, 1, (2857), 10.1038/s41467-020-16633-7)
Quinn, K. M., Hussain, T., Kraus, F., Formosa, L. E., Lam, W. K., Dagley, M. J., Saunders, E. C., Assmus, L. M., Wynne-Jones, E., Loh, L., van de Sandt, C. E., Cooper, L., Good-Jacobson, K. L., Kedzierska, K., Mackay, L. K., McConville, M. J., Ramm, G., Ryan, M. T. & La Gruta, N. L., 1 Dec 2020, In : Nature Communications. 11, 1, 1 p., 3517.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open AccessFile -
B Cells Hit a Class Ceiling in the Germinal Center
Cooper, L. & Good-Jacobson, K. L., 20 Aug 2019, In : Immunity. 51, 2, p. 206-208 3 p.Research output: Contribution to journal › Short Survey › Other › peer-review
Prizes
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Victorian Young Tall Poppy Science Award
Jacobson, Kim (Recipient), 2016
Prize: Prize (including medals and awards)
Activities
- 2 Editorial responsibility
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Journal of Immunology (Journal)
Kim Jacobson (Associate editor)
2016 → 2018Activity: Publication peer-review and editorial work types › Editorial responsibility
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Frontiers in Immunology (Journal)
Kim Jacobson (Editorial board member)
2016 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
Press / Media
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Scientists find tiny part in body that may be key to how vaccines work
22/08/18
1 Media contribution
Press/Media: Expert Comment
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Scientists unlock new secrets of disease-battling immune cells
27/09/16
1 Media contribution
Press/Media: Expert Comment
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Comment: Six steps to fairer funding for female scientists
25/10/13
1 Media contribution
Press/Media: Expert Comment