19992019

Research output per year

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Research Output

2019

Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease

Rutledge, E. A., Parvez, R. K., Short, K. M., Smyth, I. M. & McMahon, A. P., 15 Oct 2019, In : Developmental Biology. 454, 2, p. 156-169 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)
2018

Branching morphogenesis in the developing kidney 1 is not impacted by nephron formation or integration

Short, K. M., Combes, A. N., Lisnyak, V., Lefevre, J. G., Jones, L. K., Little, M. H., Hamilton, N. A. & Smyth, I. M., 31 Jul 2018, In : eLife. 7, 11 p., e38992.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

O’brien, L. L., Combes, A. N., Short, K. M., Lindström, N. O., Whitney, P. H., Cullen-McEwen, L. A., Ju, A., Abdelhalim, A., Michos, O., Bertram, J. F., Smyth, I. M., Little, M. H. & McMahon, A. P., 5 Dec 2018, In : eLife. 7, 25 p., e40392.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)
2017

Branching morphogenesis in the developing kidney is governed by rules that pattern the ureteric tree

Lefevre, J. G., Short, K. M., Lamberton, T. O., Michos, O., Graf, D., Smyth, I. M. & Hamilton, N. A., 1 Dec 2017, In : Development (Cambridge). 144, 23, p. 4377-4385 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
11 Citations (Scopus)

Imaging, analysing and interpreting branching morphogenesis in the developing kidney

Short, K. M. & Smyth, I. M., 14 Apr 2017, Kidney Development and Disease. Miller, R. K. (ed.). Springer-Verlag London Ltd., p. 233-256 24 p. (Results and Problems in Cell Differentiation; vol. 60).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)
2016

Quantification of Developmental Branching Morphogenesis

Short, K. M. & Smyth, I. M., 2016, Kidney Development, Disease, Repair and Regeneration. Little, M. (ed.). 1st ed. UK: Academia Press, p. 57-65 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

The contribution of branching morphogenesis to kidney development and disease

Short, K. M. & Smyth, I. M., 1 Dec 2016, In : Nature Reviews Nephrology. 12, p. 754-767 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

27 Citations (Scopus)

Validation of a Three-Dimensional Method for Counting and Sizing Podocytes in Whole Glomeruli

Puelles, V. G., van der Wolde, J. W., Schulze, K. E., Short, K. M., Wong, M. N., Bensley, J. G., Cullen-McEwen, L. A., Caruana, G., Hokke, S. N., Li, J., Firth, S. D., Harper, I. S., Nikolic-Paterson, D. J. & Bertram, J. F., 1 Oct 2016, In : Journal of the American Society of Nephrology. 27, 10, p. 3093-3104 12 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)
2015

A morphological investigation of sexual and lateral dimorphism in the developing metanephric kidney

Short, K. M. & Smyth, I. M., 2015, In : Scientific Reports. 5, 6 p., 15209.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

A spatially-averaged mathematical model of kidney branching morphogenesis

Zubkov, V. S., Combes, A. N., Short, K. M., Lefevre, J. G., Hamilton, N. A., Smyth, I. M., Little, M. H. & Byrne, H. M., 2015, In : Journal of Theoretical Biology. 379, p. 24-37 14 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Comparing and distinguishing the structure of biological branching

Lamberton, T. O., Lefevre, J. G., Short, K. M., Smyth, I. M. & Hamilton, N. A., 2015, In : Journal of Theoretical Biology. 365, p. 226 - 237 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci

Hadsell, D. L., Hadsell, L. A., Olea, W., Rijnkels, M., Creighton, C. J., Smyth, I. M., Short, K. M., Cox, L. L. & Cox, T. C., 2015, In : Mammalian Genome. 26, 1-2, p. 57 - 79 23 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung

Galvis, L. A., Holik, A. Z., Short, K. M., Pasquet, J., Lun, A. T. L., Blewitt, M. E., Smyth, I. M., Ritchie, M. E. & Asselin-Labat, M-L., 2015, In : Development (Cambridge). 142, 8, p. 1458 - 1469 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
34 Citations (Scopus)
2014

An integrated pipeline for the multidimensional analysis of branching morphogenesis

Combes, A., Short, K. M., Lefevre, J. G., Hamilton, N. A., Little, M. H. & Smyth, I. M., 2014, In : Nature Protocols. 9, 12, p. 2859 - 2879 21 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Global quantification of tissue dynamics in the developing mouse kidney

Short, K. M., Combes, A., Lefevre, J., Ju, A., Georgas, K., Lamberton, T., Cairncross, O., Rumballe, B. A., McMahon, A. P., Hamilton, N. A., Smyth, I. M. & Little, M. H., 2014, In : Developmental Cell. 29, 2, p. 188 - 202 15 p.

Research output: Contribution to journalArticleResearchpeer-review

129 Citations (Scopus)
2013

Altered ureteric branching morphogenesis and nephron endowment in offspring of diabetic and insulin-treated pregnancy

Hokke, S., Armitage, J., Puelles Rodriguez, V. G., Short, K. M., Jones, L. K., Smyth, I. M., Bertram, J. F. & Cullen-McEwen, L. A., 2013, In : PLoS ONE. 8, 3, 9 p., e58243.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
33 Citations (Scopus)

Spatial mapping and quantification of developmental branching morphogenesis

Short, K. M., Hodson, M. J. & Smyth, I. M., 2013, In : Development (Cambridge). 140, 2, p. 471 - 478 8 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait

Cops, E., Sashindranath, M., Daglas, M., Short, K. M., Pereira, C. D. F., Pang, T., Lijnen, R., Smyth, I. M., Hannan, A. J., Samson, A. L. & Medcalf, R. L., 2013, In : Experimental Neurology. 249C, p. 8 - 19 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
2012

Analysis of native kidney structures in three dimensions

Short, K. M. & Smyth, I. M., 2012, Kidney Development: Methods and Protocols. Michos, O. (ed.). 1st ed. USA: Humana Press, p. 95 - 107 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

9 Citations (Scopus)

Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice

Francois, M., Short, K., Secker, G. A., Combes, A., Schwarz, Q. P., Davidson, T-L., Smyth, I. M., Hong, Y-K., Harvey, N. L. & Koopman, P. A., 2012, In : Developmental Biology. 364, 2, p. 89 - 98 10 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)
2011

Heterozygous mutations of FREM1 are associated with an increased risk of isolated metopic craniosynostosis in humans and mice

Vissers, L. ELM., Cox, T. C., Maga, A. M., Short, K. M., Wiradjaja, F., Janssen, I. M., Jehee, F., Bertola, D., Liu, J., Yagnik, G., Sekiguchi, K., Kiyozumi, D., von Bokhoven, H., Marcelis, C., Cunningham, M. L., Anderson, P. J., Boyadjiev, S. A., Passos-Bueno, M. R., Veltman, J. A., Smyth, I. M. & 2 others, Buckley, M. & Roscioli, T., 2011, In : PLoS Genetics. 7, 9 (Art. No: e1002278), p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
49 Citations (Scopus)

Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma

Yallowitz, A. R., Hrycaj, S. M., Short, K. M., Smyth, I. M. & Wellik, D. M., 2011, In : PLoS ONE. 6, 8, 11 p., e23410.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
38 Citations (Scopus)

Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1

Slavotinek, A., Baranzini, S., Schanze, D., Labelle-Dumais, C., Short, K., Chao, R., Yahyavi, M., Bijlsma, E., Chua, C., Musone, S., Wheatley, A., Kwok, P-Y., Marles, S., Fryns, J-P., Maga, A., Hassan, M., Gould, D., Madireddy, L., Li, C., Cox, T. & 3 others, Smyth, I., Chudley, A. & Zenker, M., 2011, In : Journal of Medical Genetics. 48, 6, p. 375 - 382 8 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)
2010

Tomographic quantification of branching morphogenesis and renal development.

Short, K. M., Hodson, M. J. & Smyth, I. M., 2010, In : Kidney International. 77, 12, p. 1132 - 1139 8 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)
2008

Structure of the MID1 tandem B-boxes reveals an interaction reminiscent of intermolecular ring heterodimers

Tao, H., Simmons, B., Singireddy, S., Jakkidi, M., Short, K. M., Cox, T. C. & Massiah, M., 2008, In : Biochemistry. 47, 8, p. 2450 - 2457 8 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)
2007

Let's stick together: The role of the Fras1 and Frem proteins in epidermal adhesion

Short, K. M., Wiradjaja, F. & Smyth, I. M., 2007, In : IUBMB Life. 59, 7, p. 427 - 435 9 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Solution structure of the MID1 B-box2 CHC(D/C)C2H2 Zinc-binding domain: Insights into an evolutionarily conserved RING fold

Massiah, M., Matts, J. AB., Short, K. M., Simmons, B., Singireddy, S., Zou, Y. & Cox, T. C., 2007, In : Journal of Molecular Biology. 369, 1, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

67 Citations (Scopus)
2006

Solution Structure of the RBCC/TRIM B-box1 Domain of Human MID1: B-box with a RING

Massiah, M. A., Simmons, B. N., Short, K. M. & Cox, T. C., 2006, In : Journal of Molecular Biology. 358, 2, p. 532 - 545 14 p.

Research output: Contribution to journalArticleResearchpeer-review

63 Citations (Scopus)

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding

Short, K. M. & Cox, T. C., 2006, In : The Journal of Biological Chemistry. 281, 13, p. 8970 - 8980 11 p.

Research output: Contribution to journalArticleResearchpeer-review

181 Citations (Scopus)
2003

A new X-linked syndrome with agenesis of the corpus callosum, mental retardation, coloboma, micrognathia, and a mutation in the Alpha 4 gene at Xq13

Graham Jr., J. M., Wheeler, P., Tackels-Horne, D., Lin, A. E., Hall, B. D., May, M., Short, K. M., Schwartz, C. E. & Cox, T. C., 2003, In : American Journal of Medical Genetics Part A. 123A, 1, p. 37 - 44 8 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)
1999

FXY2/MID2, a gene related to the X-linked Opitz syndrome gene FXY/MID1, maps to Xq22 and encodes a FNIII domain-containing protein that associates with microtubules

Perry, J., Short, K. M., Romer, J. T., Swift, S., Cox, T. C. & Ashworth, A., 1999, In : Genomics. 62, 3, p. 385 - 394 10 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)