Projects per year
Personal profile
Biography
Professor Kieran Harvey holds dual appointments at Monash University and the Peter MacCallum Cancer Centre (Peter Mac). At Monash he runs a laboratory in the Department of Anatomy and Developmental Biology and at Peter Mac, he leads the Organogenesis and Cancer Program.
Kieran’s laboratory studies organ size control during development, using Drosophila, and how signalling pathways that control organ size are deregulated in human cancer. In particular his group focuses on the newly described Hippo tumour suppressor pathway, which he helped to discover in Prof. Iswar Hariharan’s laboratory in 2002.
Kieran performed Doctoral studies with Prof. Sharad Kumar (Hanson Institute, Adelaide), and postdoctoral studies with Prof. Iswar Hariharan (Massachusetts General Hospital/Harvard Medical Center and University of California, Berkeley). In 2006, Kieran established an independent laboratory at Peter Mac and in 2017 also joined Monash University.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Group Leader, Peter MacCallum Cancer Centre
Research area keywords
- Signalling pathways
- Drosophila
- organogenesis
Collaborations and top research areas from the last five years
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Defining how signalling pathways cooperate to regulate organ size
1/01/23 → 31/12/25
Project: Research
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Investigating Hippo-regulated transcription at single molecule resolution
1/03/22 → 28/02/25
Project: Research
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Tracking the single molecule dynamics of transcription factors in a living cell
Hinde, E., Polo, J., Harvey, K., Blewitt, M. E., Fischer, T., Arkell, R. M., Bell, T., Gleeson, P. A., Watt, M., Prawer, S. D. & McMillan, P.
Australian Research Council (ARC)
28/05/21 → 27/05/22
Project: Research
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How do neurons maintain their fate?
Harvey, K., Schroeder, J. & Cheng, L.
17/06/19 → 16/06/22
Project: Research
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Basal spot junctions of Drosophila epithelial tissues respond to morphogenetic forces and regulate Hippo signaling
Kroeger, B., Manning, S. A., Fonseka, Y., Oorschot, V., Crawford, S. A., Ramm, G. & Harvey, K. F., 22 Jan 2024, In: Developmental Cell. 59, 2, p. 262-279 25 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
Kulkarni, A., Mohan, V., Tang, T. T., Post, L., Chan, Y. C., Manning, M., Thio, N., Parker, B. L., Dawson, M. A., Rosenbluh, J., Vissers, J. H. A. & Harvey, K. F., 2024, (Accepted/In press) In: EMBO Reports. p. 1-26 26 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3
Thilakasiri, P., O’keefe, R. N., To, S. Q., Chisanga, D., Eissmann, M. F., Carli, A. L. E., Duscio, B., Baloyan, D., Dmello, R. S., Williams, D., Mariadason, J., Poh, A. R., Pal, B., Kile, B. T., Vissers, J. H. A., Harvey, K. F., Buchert, M., Shi, W., Ernst, M. & Chand, A. L., Feb 2024, In: Life Science Alliance. 7, 2, 17 p., e202302411.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Dedifferentiation-derived neural stem cells exhibit perturbed temporal progression
Veen, K., Nguyen, P. K., Froldi, F., Dong, Q., Alvarez-Ochoa, E., Harvey, K. F., McMullen, J. P. D., Marshall, O., Jusuf, P. R. & Cheng, L. Y., 5 Jun 2023, In: EMBO Reports. 24, 6, 19 p., e55837.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
NDR kinase tricornered genetically interacts with Ccm3 and metabolic enzymes in Drosophila melanogaster tracheal development
Hudson, J., Paul, S., Veraksa, A., Ghabrial, A., Harvey, K. F. & Poon, C., Mar 2023, In: G3: Genes, Genomes, Genetics. 13, 3, 14 p., jkad013.Research output: Contribution to journal › Article › Research › peer-review
Open Access