Projects per year
Personal profile
Biography
Professor Kieran Harvey holds dual appointments at Monash University and the Peter MacCallum Cancer Centre (Peter Mac). At Monash he runs a laboratory in the Department of Anatomy and Developmental Biology and at Peter Mac, he leads the Organogenesis and Cancer Program.
Kieran’s laboratory studies organ size control during development, using Drosophila, and how signalling pathways that control organ size are deregulated in human cancer. In particular his group focuses on the newly described Hippo tumour suppressor pathway, which he helped to discover in Prof. Iswar Hariharan’s laboratory in 2002.
Kieran performed Doctoral studies with Prof. Sharad Kumar (Hanson Institute, Adelaide), and postdoctoral studies with Prof. Iswar Hariharan (Massachusetts General Hospital/Harvard Medical Center and University of California, Berkeley). In 2006, Kieran established an independent laboratory at Peter Mac and in 2017 also joined Monash University.
External positions
Group Leader, Peter MacCallum Cancer Centre
Research area keywords
- Signalling pathways
- Drosophila
- organogenesis
Network
Projects
- 2 Active
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How do neurons maintain their fate?
Harvey, K., Schroeder, J. & Cheng, L.
17/06/19 → 16/06/22
Project: Research
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Research output
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The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis
Zhang, X., Yang, L., Szeto, P., Abali, G. K., Zhang, Y., Kulkarni, A., Amarasinghe, K., Li, J., Vergara, I. A., Molania, R., Papenfuss, A. T., McLean, C., Shackleton, M. & Harvey, K. F., 19 Jun 2020, (Accepted/In press) In : Oncogene. 15 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
The regulation of Yorkie, YAP and TAZ: new insights into the Hippo pathway
Manning, S. A., Kroeger, B. & Harvey, K. F., 27 Apr 2020, In : Development. 147, 8, 10 p., 179069.Research output: Contribution to journal › Review Article › Research › peer-review
8 Citations (Scopus) -
Somatic hypermutation of the YAP oncogene in a human cutaneous melanoma
Zhang, X., Tang, J. Z., Vergara, I. A., Zhang, Y., Szeto, P., Yang, L., Mintoff, C., Colebatch, A., McIntosh, L., Mitchell, K. A., Shaw, E., Rizos, H., Long, G. V., Hayward, N., McArthur, G. A., Papenfuss, A. T., Harvey, K. F. & Shackleton, M., 1 Jul 2019, In : Molecular Cancer Research. 17, 7, p. 1435-1449 15 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
The dPix-Git complex is essential to coordinate epithelial morphogenesis and regulate myosin during Drosophila egg chamber development
Dent, L. G., Manning, S. A., Kroeger, B., Williams, A. M., Saiful Hilmi, A. J., Crea, L., Kondo, S., Horne-Badovinac, S. & Harvey, K. F., 22 May 2019, In : PLoS Genetics. 15, 5, 31 p., e1008083.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile2 Citations (Scopus) -
A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster
Poon, C. L. C., Liu, W., Song, Y., Gomez, M., Kulaberoglu, Y., Zhang, X., Xu, W., Veraksa, A., Hergovich, A., Ghabrial, A. & Harvey, K. F., 3 Dec 2018, In : Developmental Cell. 47, 5, p. 564-575 12 p.Research output: Contribution to journal › Article › Research › peer-review
12 Citations (Scopus)