Projects per year
Personal profile
Biography
Professor Kieran Harvey holds dual appointments at Monash University and the Peter MacCallum Cancer Centre (Peter Mac). At Monash he runs a laboratory in the Department of Anatomy and Developmental Biology and at Peter Mac, he leads the Organogenesis and Cancer Program.
Kieran’s laboratory studies organ size control during development, using Drosophila, and how signalling pathways that control organ size are deregulated in human cancer. In particular his group focuses on the newly described Hippo tumour suppressor pathway, which he helped to discover in Prof. Iswar Hariharan’s laboratory in 2002.
Kieran performed Doctoral studies with Prof. Sharad Kumar (Hanson Institute, Adelaide), and postdoctoral studies with Prof. Iswar Hariharan (Massachusetts General Hospital/Harvard Medical Center and University of California, Berkeley). In 2006, Kieran established an independent laboratory at Peter Mac and in 2017 also joined Monash University.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Group Leader, Peter MacCallum Cancer Centre
Research area keywords
- Signalling pathways
- Drosophila
- organogenesis
Network
-
Investigating Hippo-regulated transcription at single molecule resolution
1/01/22 → 31/12/24
Project: Research
-
Tracking the single molecule dynamics of transcription factors in a living cell
Hinde, E., Polo, J., Harvey, K., Blewitt, M., Fischer, T., Arkell, R. M., Bell, T., Gleeson, P. A., Watt, M., Prawer, S. D. & McMillan, P.
Australian Research Council (ARC)
28/05/21 → 27/05/22
Project: Research
-
How do neurons maintain their fate?
Harvey, K., Schroeder, J. & Cheng, L.
17/06/19 → 16/06/22
Project: Research
-
-
The Hippo pathway uses different machinery to control cell fate and organ size
Pojer, J. M., Manning, S. A., Kroeger, B., Kondo, S. & Harvey, K. F., 20 Aug 2021, In: iScience. 24, 8, 17 p., 102830.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
Vervoort, S. J., Welsh, S. A., Devlin, J. R., Barbieri, E., Knight, D. A., Offley, S., Bjelosevic, S., Costacurta, M., Todorovski, I., Kearney, C. J., Sandow, J. J., Fan, Z., Blyth, B., McLeod, V., Vissers, J. H. A., Pavic, K., Martin, B. P., Gregory, G., Demosthenous, E., Zethoven, M. & 13 others, , 10 Jun 2021, In: Cell. 184, 12, p. 3143-3162.E32 52 p.Research output: Contribution to journal › Article › Research › peer-review
14 Citations (Scopus) -
Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease
Watt, K. I., Henstridge, D. C., Ziemann, M., Sim, C. B., Montgomery, M. K., Samocha-Bonet, D., Parker, B. L., Dodd, G. T., Bond, S. T., Salmi, T. M., Lee, R. S., Thomson, R. E., Hagg, A., Davey, J. R., Qian, H., Koopman, R., El-Osta, A., Greenfield, J. R., Watt, M. J., Febbraio, M. A. & 5 others, , Dec 2021, In: Nature Communications. 12, 1, 14 p., 2887.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Conserved Tao kinase activity regulates dendritic arborization, cytoskeletal dynamics, and sensory function in Drosophila
Hu, C., Kanellopoulos, A. K., Richter, M., Petersen, M., Konietzny, A., Tenedini, F. M., Hoyer, N., Cheng, L., Poon, C. L. C., Harvey, K. F., Windhorst, S., Parrish, J. Z., Mikhaylova, M., Bagni, X. C., de Anda, F. C. & Soba, X. P., 26 Feb 2020, In: Journal of Neuroscience. 40, 9, p. 1819-1833 15 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
Pits and CtBP control tissue growth in drosophila melanogaster with the hippo pathway transcription repressor Tgi
Vissers, J. H. A., Dent, L. G., House, C. M., Kondo, S. & Harvey, K. F., May 2020, In: Genetics. 215, 1, p. 117-128 12 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus)