Projects per year
Personal profile
Biography
Dr Kooi Yeong Khaw joined the School of Pharmacy, Monash Malaysia as an Assistant Lecturer in 2019. He obtained his PhD from the School of Pharmacy, The University of Queensland. Kooi-Yeong research interests are drug discovery, green extraction and, pharmaceutical analysis. His long-term career goal is to discover a cost-effective and efficacy drug to improve the quality of life of human beings.
Research interests
Pharmaceutical Biodiscovery
The primary research interest of our laboratory is focused on Pharmaceutical biodiscovery. We are interested to discover and harness the potential of natural molecules as the next-generation drug candidate for neurodegenerative diseases (Alzheimer's disease) and cancer.
The laboratory uses various techniques such as extraction, fractionation, semi-synthesis, enzymatic, and molecular biology to identify and characterise novel compounds. Potent compounds will be carried forward to evaluate their mechanisms of action in-vivo with our local and international collaborators.
Green Chemistry
The use of a sustainable and green extraction method for natural products is required in the modern age to minimize environmental impact and ensure the safety of human beings. One of the ways is to reduce and replace the use of toxic, flammable and corrosive solvents in the extraction processes. The use of solventless systems, supercritical fluids and ionic liquids have been advocated as an alternative method to replace the notoriously unfavourable organic solvents. Supercritical carbon dioxide extraction offers alternative means for the extraction of natural products. It has been used to extract value-added bioactive compounds such as α-tocopherol, hyperforin and carotenoids. Our laboratory is interested to optimise factors that potentially governed the extraction processes and extraction of novel molecules from natural resources.
Pharmaceutical analysis
Another research domain of our laboratory focused on method development and analysis of active ingredients and contaminants in pharmaceuticals, cosmeceuticals and supplements.
We are keen to work together with researchers from different fields. Prospective postgraduate students with or without funding are welcome to discuss their research interests and work together with us.
Monash teaching commitment
PHR 1022 How Medicine works
PHR 2041 Pain, Dermatology and Wound
PHR 5252 Inquiry & Innovation Results
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Pharmaceutical chemistry, PhD, University of Queensland
Research area keywords
- Medicinal Chemistry
- Pharmaceutical Analysis
- Alzheimer's disease
- Natural product chemistry
- Drug discovery
- Neuroscience
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The Neuroprotective Molecular Targets and Pathways Identification, and the Effectiveness of Intranasally Administered Zerumbone Lipid Nanoparticles in Neurodegenerative Sprague-Dawley Rat Model
Chee Wun, H. (Primary Chief Investigator (PCI)), Ng, H. S. (Chief Investigator (CI)), Hassan, Z. (Chief Investigator (CI)), Yong Sze, O. (Chief Investigator (CI)), Kooi Yeong, K. (Chief Investigator (CI)) & Ogino, C. (Chief Investigator (CI))
7/09/21 → 6/09/24
Project: Research
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The synergy of growth hormone and exercise on brain recovery after experimental stroke.
Ong, L. K. & Kooi Yeong, K.
2/01/21 → 30/12/22
Project: Research
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Bioactivity guided isolation of bioactive compounds from the methanol extract of Murraya koneigii
1/10/22 → 1/10/23
Project: Research
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Development of Engkabang as high-quality cosmeceutical products and new generation functional food
Chun Wie, C. (Primary Chief Investigator (PCI)), Chee Wun, H. (Chief Investigator (CI)), Kooi Yeong, K. (Chief Investigator (CI)), Khong, N. (Chief Investigator (CI)), Yong Sze, O. (Chief Investigator (CI)) & Lee, R. (Chief Investigator (CI))
1/12/23 → 28/02/26
Project: Research
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Anti-cholinesterase profile of Murraya koenigii (L.) Spreng essential oil and its chemical constituents
Wee, A. S., Thew, H. Y., Liew, S. Y., Tan, W. N. & Khaw, K. Y., 15 Oct 2024, In: Journal of Essential Oil-Bearing Plants. 27, 5, p. 1449-1459 11 p.Research output: Contribution to journal › Article › Research › peer-review
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ESTIMATION OF DRUG CONSUMPTION IN KUANTAN, PAHANG, MALAYSIA VIA WASTEWATER-BASED DRUG EPIDEMIOLOGY
Izani, M. A., Sabri, N. A., Khaw, K. Y., Othman, I. & Tay, J. H., 2024, In: Malaysian Journal of Analytical Sciences. 28, 5, p. 975-984 10 p.Research output: Contribution to journal › Article › Research › peer-review
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Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
Loh, J. S., Mak, W. Q., Tan, L. K. S., Ng, C. X., Chan, H. H., Yeow, S. H., Foo, J. B., Ong, Y. S., How, C. W. & Khaw, K. Y., Dec 2024, In: Signal Transduction and Targeted Therapy. 9, 1, 53 p., 37.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access256 Citations (Scopus) -
Probing the anti-Aβ42 aggregation and protective effects of prenylated xanthone against Aβ42-induced toxicity in transgenic Caenorhabditis elegans model
Thew, H. Y., Boon Keat, K., Tan, Y. C., Ong, Y. S., Parat, M. O., Murugaiyah, V., Goh, B. H. & Khaw, K. Y., 1 May 2024, In: Chemico-Biological Interactions. 394, 11 p., 110978.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Streptomyces sp. MUM 195J: A Promising Probiotic for Controlling Vibrio parahaemolyticus Infection in Aquaculture
Goh, J. X. H., Tan, L. T. H., Law, J. W. F., Kuppusamy, G., Janaranjani, M., Khaw, K. Y., Yap, W. H., Chan, K. G., Letchumanan, V., Lee, L. H. & Goh, B. H., 12 Jun 2024, In: Progress in Microbes and Molecular Biology. 7, 1, 44 p., a0000443.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)
Prizes
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Farm-Mate-S1 The Game Changer for the Shrimp Farming Industry.
Letchumanan, V. (Recipient), Goh, B. H. (Recipient), Kooi Yeong, K. (Recipient), Goh, J. X. H. (Recipient), Loh Teng-Hern, T. (Recipient), Lee, L.-H. (Recipient), Woan-Fei, J. L. (Recipient) & Kuppusamy, G. (Recipient), 2023
Prize: Prize (including medals and awards)
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From grave to cradle: Hunting new antimicrobials through sustainable drug discovery
Yie Kie, C. (Recipient), Yeong, K. Y. (Recipient), Joo Kheng, Emily, G. (Recipient), Yau Yan, L. (Recipient), Yuen Lin, C. (Recipient), Chee Wei, A. (Recipient), Kooi Yeong, K. (Recipient), Ahemad, N. (Recipient), Robinson, A. (Recipient), Andrews, P. (Recipient), Prasetyoputri, A. (Recipient), Ahmad Kamil Hj Mohd Jaafar (Recipient) & Zainal Baharum (Recipient), 22 Jul 2022
Prize: Prize (including medals and awards)
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Grant reviewer for European Science foundatio
Kooi Yeong, K. (Fellow)
13 Jun 2024Activity: External Academic Engagement › Grant review responsibilities
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University of Adelaide
Kooi Yeong, K. (Visiting researcher)
7 Jul 2023 → 28 Oct 2023Activity: Visiting an external institution types › Visiting an external academic institution