Projects per year
Personal profile
Biography
Dr Yeong Keng Yoon graduated with a PhD from Universiti Sains Malaysia specialising in medicinal chemistry. Over 20 original research and review papers were published in the area drug design and discovery, covering various diseases such as cancer, Alzheimer’s, and tuberculosis. Before joining Monash University Malaysia as a lecturer in the School of Science, Dr Yeong spent 5 years as a research scientist for a local biotech startup and the next 6 years as a senior research scientist with Romer Labs, a multinational food diagnostic company. In both companies, he work on small molecule chemical modification, bioconjugation as well as antibody and immunoassay development.
Dr Yeong's primary research interests includes organic synthesis of novel small molecules targeting age-related diseases such as cancer and Alzheimer’s. Also of interest is the modification of natural products for bioactivity as well as novel fluorescent drug molecules with theranostic applications. His current research projects revolve around designing sirtuin modulators, multi-target directed ligand inhibitors for Alzheimer’s disease and telomerase inhibitors for cancer therapy.
Research interests
- Organic synthesis of novel small molecules targeting age-related diseases such as cancer and Alzheimer’s.
- Modification of natural products for bioactivity as well as novel fluorescent drug molecules with theranostic applications
Research interests
- CHM3930 (Medicinal chemistry)
- CHM3922 (Advanced organic chemistry)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Network
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A novel strategy to characterize virulence factors and develop DNAzymes as antivirulence agents using the Shigella-Caenorhabditis elegans infection model.
Hock Siew, T., Mohamad, S. B., Narayanan, K., Yeong, K. Y. & Ayub, Q.
1/11/20 → 31/10/23
Project: Research
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Design, synthesis and mechanistic studies of novel benzimidazole sirtuin inhibitors as a novel class of therapeutics against drug-resistant oral cancer cells
Yeong, K. Y., Ahemad, N., Lee, W., Osman, H., Yuen Lin, C. & Hock Siew, T.
1/11/20 → 31/10/23
Project: Research
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Role of sirtuins in the regulation of Toxoplasma gondii interconversion between tachyzoite and bradyzoite cysts
Chow, S. C., Keang Peng, S. & Yeong, K. Y.
15/08/17 → 14/02/20
Project: Research
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Advances in cosmeceutical nanotechnology for hyperpigmentation treatment
Tangau, M. J., Chong, Y. K. & Yeong, K. Y., Aug 2022, In: Journal of Nanoparticle Research. 24, 8, 18 p., 155.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile3 Citations (Scopus) -
Current trends of benzothiazoles in drug discovery: a patent review (2015–2020)
Law, C. S. W. & Yeong, K. Y., 2022, In: Expert Opinion on Therapeutic Patents. 32, 3, p. 299-315 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
4 Citations (Scopus) -
Five-Membered Rings With Three Oxygen or Sulfur Atoms in 1,2,4-Positions
Yeong, K. Y., Stephens, L. & Ling, I., 2022, Comprehensive Heterocyclic Chemistry IV: A Review of the Literature 2008-2021. Smith, J. A. (ed.). 1st ed. Elsevier, Vol. 6. p. 146-181 36 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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Fruits for seizures? A systematic review on the potential anti-convulsant effects of fruits and their phytochemicals
Siang, L. H., Arulsamy, A., Yoon, Y. K. & Shaikh, M. F., 2022, In: Current Neuropharmacology. 20, 10, p. 1925-1940 16 p.Research output: Contribution to journal › Article › Research › peer-review
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Modern vaccine development via reverse vaccinology to combat antimicrobial resistance
Tobuse, A. J., Ang, C. W. & Yeong, K. Y., 1 Aug 2022, In: Life Sciences. 302, 14 p., 120660.Research output: Contribution to journal › Review Article › Research › peer-review
Prizes
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Faculty of Science Dean's Award for Teaching Excellence
Yeong, Keng Yoon (Recipient), 2020
Prize: Prize (including medals and awards)
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Pro Vice-Chancellor’s (PVC) Awards for Excellence in Research - ECR
Yeong, Keng Yoon (Recipient), 2021
Prize: Prize (including medals and awards)