Research Output per year
Research Output 2010 2019
2019
Comment on: CG258 Klebsiella pneumoniae isolates without β-lactam resistance at the onset of the carbapenem-resistant Enterobacteriaceae epidemic in New York City
Wyres, K. L., Lam, M. M. C. & Holt, K. E., 1 Mar 2019, In : Journal of Antimicrobial Chemotherapy. 74, 3, p. 831-833 3 p.Research output: Contribution to journal › Article › Other › peer-review
Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15
Lam, M. M. C., Wyres, K. L., Wick, R. R., Judd, L. M., Fostervold, A., Holt, K. E. & Löhr, I. H., May 2019, In : Journal of Antimicrobial Chemotherapy. 74, 5, p. 1218–1222 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae
Wyres, K. L., Wick, R. R., Judd, L. M., Froumine, R., Tokolyi, A., Gorrie, C. L., Lam, M. M. C., Duchêne, S., Jenney, A. & Holt, K. E., 1 Apr 2019, In : PLoS Genetics. 15, 4, 25 p., e1008114.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307
Wyres, K. L., Hawkey, J., Hetland, M. A. K., Fostervold, A., Wick, R. R., Judd, L. M., Hamidian, M., Howden, B. P., Löhr, I. H. & Holt, K. E., 1 Mar 2019, In : Journal of Antimicrobial Chemotherapy. 74, 3, p. 577-581 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Small IncQ1 and col-like plasmids harboring bla KPC-2 and non-Tn4401 elements (NTE KPC -IId) in high-risk lineages of Klebsiella pneumoniae CG258
Cerdeira, L. T., Lam, M. M. C., Wyres, K. L., Wick, R. R., Judd, L. M., Lopes, R., Ribas, R. M., Morais, M. M., Holt, K. E. & Lincopan, N., 1 Mar 2019, In : Antimicrobial Agents and Chemotherapy. 63, 3, 4 p., e02140-18.Research output: Contribution to journal › Letter › Research › peer-review
2018
Antimicrobial-resistant klebsiella pneumoniae carriage and infection in specialized geriatric care wards linked to acquisition in the referring hospital
Gorrie, C. L., Mirceta, M., Wick, R. R., Judd, L. M., Wyres, K. L., Thomson, N. R., Strugnell, R. A., Pratt, N. F., Garlick, J. S., Watson, K. M., Hunter, P. C., McGloughlin, S. A., Spelman, D. W., Jenney, A. W. J. & Holt, K. E., 2 Jul 2018, In : Clinical Infectious Diseases. 67, 2, p. 161-170 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Best practice data life cycle approaches for the life sciences
Griffin, P. C., Khadake, J., LeMay, K. S., Lewis, S. E., Orchard, S., Pask, A., Pope, B., Roessner, U., Russell, K., Seemann, T., Treloar, A., Tyagi, S., Christiansen, J. H., Dayalan, S., Gladman, S., Hangartner, S. B., Hayden, H. L., Ho, W. W. H., Keeble-Gagnère, G., Korhonen, P. K. & 7 others, 4 Jun 2018, In : F1000Research. 6, 22 p., 1618.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations
Lam, M. MC., Wick, R. R., Wyres, K. L., Gorrie, C. L., Judd, L. M., Jenney, A. WJ., Brisse, S. & Holt, K. E., 1 Sep 2018, In : Microbial genomics. 4, 9, 14 p., 000196.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Kaptive web: User-Friendly capsule and lipopolysaccharide serotype prediction for Klebsiella genomes
Wick, R. R., Heinz, E., Holt, K. E. & Wyres, K. L., 1 Jun 2018, In : Journal of Clinical Microbiology. 56, 6, 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria
Wyres, K. L. & Holt, K. E., 1 Oct 2018, In : Current Opinion in Microbiology. 45, p. 131-139 9 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination
Lam, M. M. C., Wyres, K. L., Duchêne, S., Wick, R. R., Judd, L. M., Gan, Y. H., Hoh, C. H., Archuleta, S., Molton, J. S., Kalimuddin, S., Koh, T. H., Passet, V., Brisse, S. & Holt, K. E., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 2703.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae
Lam, M. M. C., Wyres, K. L., Judd, L. M., Wick, R. R., Jenney, A., Brisse, S. & Holt, K. E., 29 Oct 2018, In : Genome Medicine. 10, 1, 15 p., 77.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2016
Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population
Lee, I. R., Molton, J. S., Wyres, K. L., Gorrie, C., Wong, J., Hoh, C. H., Teo, J., Kalimuddin, S., Lye, D. C., Archuleta, S., Holt, K. E. & Gan, Y. H., 13 Jul 2016, In : Scientific Reports. 6, 12 p., 29316.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Identification of Klebsiella capsule synthesis loci from whole genome data
Wyres, K. L., Wick, R. R., Gorrie, C., Jenney, A., Follador, R., Thomson, N. R. & Holt, K. E., 1 Dec 2016, In : Microbial genomics. 2, 12, 15 p., e000102.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Klebsiella pneumoniae Population Genomics and Antimicrobial-Resistant Clones
Wyres, K. L. & Holt, K. E., 1 Dec 2016, In : Trends in Microbiology. 24, 12, p. 944-956 13 p.Research output: Contribution to journal › Review Article › Research › peer-review
Paradoxical Hypersusceptibility of Drug-resistant Mycobacterium tuberculosis to β-lactam Antibiotics
Cohen, K. A., El-Hay, T., Wyres, K. L., Weissbrod, O., Munsamy, V., Yanover, C., Aharonov, R., Shaham, O., Conway, T. C., Goldschmidt, Y., Bishai, W. R. & Pym, A. S., 1 Jan 2016, In : EBioMedicine. 9, p. 170-179 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
The diversity of Klebsiella pneumoniae surface polysaccharides
Follador, R., Heinz, E., Wyres, K. L., Ellington, M. J., Kowarik, M., Holt, K. E. & Thomson, N. R., 1 Aug 2016, In : Microbial genomics. 2, 8, 15 p., e000073.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2015
A platform for leveraging next generation sequencing for routine microbiology and public health use
Rusu, L. I., Wyres, K. L., Reumann, M., Queiroz, C., Bojovschi, A., Conway, T., Garg, S. K., Edwards, D. J., Hogg, G. G. & Holt, K. E., Dec 2015, In : Health Information Science and Systems. 3, 1, 7 p., S7.Research output: Contribution to journal › Article › Other › peer-review
Open Access
File
Extensive capsule locus variation and large-scale genomic recombination within the Klebsiella pneumoniae clonal group 258
Wyres, K. L., Gorrie, C., Edwards, D. J., Wertheim, H. F. L., Hsu, L. Y., Van Kinh, N., Zadoks, R., Baker, S. & Holt, K. E., 1 Jan 2015, In : Genome Biology and Evolution. 7, 5, p. 1267-1279 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2014
Spatio-temporal information and knowledge representation of disease incidence and respective intervention strategies
Davis, M., Von Cavallar, S., Wyres, K. L., Reumann, M., Sepulveda, M. J. & Rogers, P., 1 Jan 2014, e-Health - For Continuity of Care - Proceedings of MIE 2014. Pape-Haugaard, L., Seroussi Brigitte, B., Saka, O., Lovis, C., Hasman, A. & Andersen, S. K. (eds.). IOS Press, p. 1173-1177 5 p. (Studies in Health Technology and Informatics; vol. 205).Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review
Open Access
File
Streptococcus pneumoniae carriage prevalence in Nepal: Evaluation of a method for delayed transport of samples from remote regions and implications for vaccine implementation
Hanieh, S., Hamaluba, M., Kelly, D. F., Metz, J. A., Wyres, K. L., Fisher, R., Pradhan, R., Shakya, D., Shrestha, L., Shrestha, A., Joshi, A., Habens, J., Maharjan, B. D., Thorson, S., Bohler, E., Yu, L. M., Kelly, S., Plested, E., John, T., Werno, A. M. & 4 others, 6 Jun 2014, In : PLoS ONE. 9, 6, 9 p., e98739.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
WGS analysis and interpretation in clinical and public health microbiology laboratories: What are the requirements and how do existing tools compare?
Wyres, K. L., Conway, T. C., Garg, S., Queiroz, C., Reumann, M., Holt, K. & Rusu, L. I., 11 Jun 2014, In : Pathogens. 3, 2, p. 437-458 22 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
2013
Evidence of antimicrobial resistance-conferring genetic elements among pneumococci isolated prior to 1974
Wyres, K. L., van Tonder, A., Lambertsen, L. M., Hakenbeck, R., Parkhill, J., Bentley, S. D. & Brueggemann, A. B., 24 Jul 2013, In : BMC Genomics. 14, 1, 500.Research output: Contribution to journal › Article › Research › peer-review
Pneumococcal capsular switching: A historical perspective
Wyres, K. L., Lambertsen, L. M., Croucher, N. J., McGee, L., Von Gottberg, A., Liñares, J., Jacobs, M. R., Kristinsson, K. G., Beall, B. W., Klugman, K. P., Parkhill, J., Hakenbeck, R., Bentley, S. D. & Brueggemann, A. B., 1 Feb 2013, In : Journal of Infectious Diseases. 207, 3, p. 439-449 11 p.Research output: Contribution to journal › Article › Research › peer-review
2012
The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success
Wyres, K. L., Lambertsen, L. M., Croucher, N. J., McGee, L., von Gottberg, A., Liñares, J., Jacobs, M. R., Kristinsson, K. G., Beall, B. W., Klugman, K. P., Parkhill, J., Hakenbeck, R., Bentley, S. D. & Brueggemann, A. B., 16 Nov 2012, In : Genome Biology. 13, 11, R103.Research output: Contribution to journal › Article › Research › peer-review
2010
Environmental factors determining the epidemiology and population genetic structure of the bacillus cereus group in the field
Raymond, B., Wyres, K. L., Sheppard, S. K., Ellis, R. J. & Bonsall, M. B., 1 May 2010, In : PLoS Pathogens. 6, 5, p. 1-13 13 p.Research output: Contribution to journal › Article › Research › peer-review