Kelly Wyres

Research output

Research output per year 2010 2021

• 25 Article
• 4 Review Article
• 1 Conference Paper
• 1 Letter

Research output per year

Research output per year

Search results

• 2021

  Silent spread of mobile colistin resistance gene mcr-9.1 on IncHI2 ‘superplasmids’ in clinical carbapenem-resistant Enterobacterales

  Macesic, N., Blakeway, L. V., Stewart, J. D., Hawkey, J., Wyres, K. L., Judd, L. M., Wick, R. R., Jenney, A. W., Holt, K. E. & Peleg, A. Y., 2021, (Accepted/In press) In: Clinical Microbiology and Infection. 7 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
• 2020

  Diversity and evolution of surface polysaccharide synthesis loci in Enterobacteriales

  Holt, K. E., Lassalle, F., Wyres, K. L., Wick, R. & Mostowy, R. J., 1 Jul 2020, In: ISME Journal. 14, 7, p. 1713-1730 18 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

• Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

  Wyres, K. L., Nguyen, T. N. T., Lam, M. M. C., Judd, L. M., van Vinh Chau, N., Dance, D. A. B., Ip, M., Karkey, A., Ling, C. L., Miliya, T., Newton, P. N., Lan, N. P. H., Sengduangphachanh, A., Turner, P., Veeraraghavan, B., Vinh, P. V., Vongsouvath, M., Thomson, N. R., Baker, S. & Holt, K. E., 16 Jan 2020, In: Genome Medicine. 12, 1, 16 p., 11.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  19 Citations (Scopus)

• Identification of Acinetobacter baumannii loci for capsular polysaccharide (KL) and lipooligosaccharide outer core (OCL) synthesis in genome assemblies using curated reference databases compatible with Kaptive

  Wyres, K. L., Cahill, S. M., Holt, K. E., Hall, R. M. & Kenyon, J. J., 1 Mar 2020, In: Microbial Genomics. 6, 3, 12 p., 000339.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  20 Citations (Scopus)

• Population genomics of Klebsiella pneumoniae

  Wyres, K. L., Lam, M. M. C. & Holt, K. E., 1 Jun 2020, In: Nature Reviews Microbiology. 18, 6, p. 344-359 16 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  47 Citations (Scopus)
• 2019

  Comment on: CG258 Klebsiella pneumoniae isolates without β-lactam resistance at the onset of the carbapenem-resistant Enterobacteriaceae epidemic in New York City

  Wyres, K. L., Lam, M. M. C. & Holt, K. E., 1 Mar 2019, In: Journal of Antimicrobial Chemotherapy. 74, 3, p. 831-833 3 p.

  Research output: Contribution to journal › Article › Other › peer-review

• Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15

  Lam, M. M. C., Wyres, K. L., Wick, R. R., Judd, L. M., Fostervold, A., Holt, K. E. & Löhr, I. H., May 2019, In: Journal of Antimicrobial Chemotherapy. 74, 5, p. 1218-1222 5 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  26 Citations (Scopus)

• Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

  Wyres, K. L., Wick, R. R., Judd, L. M., Froumine, R., Tokolyi, A., Gorrie, C. L., Lam, M. M. C., Duchêne, S., Jenney, A. & Holt, K. E., 1 Apr 2019, In: PLoS Genetics. 15, 4, 25 p., e1008114.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  48 Citations (Scopus)

• Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307

  Wyres, K. L., Hawkey, J., Hetland, M. A. K., Fostervold, A., Wick, R. R., Judd, L. M., Hamidian, M., Howden, B. P., Löhr, I. H. & Holt, K. E., 1 Mar 2019, In: Journal of Antimicrobial Chemotherapy. 74, 3, p. 577-581 5 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  43 Citations (Scopus)

• Small IncQ1 and col-like plasmids harboring bla _KPC-2 and non-Tn4401 elements (NTE _KPC -IId) in high-risk lineages of Klebsiella pneumoniae CG258

  Cerdeira, L. T., Lam, M. M. C., Wyres, K. L., Wick, R. R., Judd, L. M., Lopes, R., Ribas, R. M., Morais, M. M., Holt, K. E. & Lincopan, N., 1 Mar 2019, In: Antimicrobial Agents and Chemotherapy. 63, 3, 4 p., e02140-18.

  Research output: Contribution to journal › Letter › Research › peer-review
  13 Citations (Scopus)
• 2018

  Antimicrobial-resistant klebsiella pneumoniae carriage and infection in specialized geriatric care wards linked to acquisition in the referring hospital

  Gorrie, C. L., Mirceta, M., Wick, R. R., Judd, L. M., Wyres, K. L., Thomson, N. R., Strugnell, R. A., Pratt, N. F., Garlick, J. S., Watson, K. M., Hunter, P. C., McGloughlin, S. A., Spelman, D. W., Jenney, A. W. J. & Holt, K. E., 2 Jul 2018, In: Clinical Infectious Diseases. 67, 2, p. 161-170 10 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  32 Citations (Scopus)

• Best practice data life cycle approaches for the life sciences

  Griffin, P. C., Khadake, J., LeMay, K. S., Lewis, S. E., Orchard, S., Pask, A., Pope, B., Roessner, U., Russell, K., Seemann, T., Treloar, A., Tyagi, S., Christiansen, J. H., Dayalan, S., Gladman, S., Hangartner, S. B., Hayden, H. L., Ho, W. W. H., Keeble-Gagnère, G., Korhonen, P. K. & 7 others, Neish, P., Prestes, P. R., Richardson, M. F., Watson-Haigh, N. S., Wyres, K. L., Young, N. D. & Schneider, M. V., 4 Jun 2018, In: F1000Research. 6, 22 p., 1618.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

• Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations

  Lam, M. MC., Wick, R. R., Wyres, K. L., Gorrie, C. L., Judd, L. M., Jenney, A. WJ., Brisse, S. & Holt, K. E., 1 Sep 2018, In: Microbial Genomics. 4, 9, 14 p., 000196.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  74 Citations (Scopus)

• Kaptive web: User-Friendly capsule and lipopolysaccharide serotype prediction for Klebsiella genomes

  Wick, R. R., Heinz, E., Holt, K. E. & Wyres, K. L., 1 Jun 2018, In: Journal of Clinical Microbiology. 56, 6, 10 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  75 Citations (Scopus)

• Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria

  Wyres, K. L. & Holt, K. E., 1 Oct 2018, In: Current Opinion in Microbiology. 45, p. 131-139 9 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access

  File
  80 Citations (Scopus)

• Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination

  Lam, M. M. C., Wyres, K. L., Duchêne, S., Wick, R. R., Judd, L. M., Gan, Y. H., Hoh, C. H., Archuleta, S., Molton, J. S., Kalimuddin, S., Koh, T. H., Passet, V., Brisse, S. & Holt, K. E., 1 Dec 2018, In: Nature Communications. 9, 1, 10 p., 2703.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  60 Citations (Scopus)

• Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae

  Lam, M. M. C., Wyres, K. L., Judd, L. M., Wick, R. R., Jenney, A., Brisse, S. & Holt, K. E., 29 Oct 2018, In: Genome Medicine. 10, 1, 15 p., 77.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  40 Citations (Scopus)
• 2016

  Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population

  Lee, I. R., Molton, J. S., Wyres, K. L., Gorrie, C., Wong, J., Hoh, C. H., Teo, J., Kalimuddin, S., Lye, D. C., Archuleta, S., Holt, K. E. & Gan, Y. H., 13 Jul 2016, In: Scientific Reports. 6, 12 p., 29316.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  40 Citations (Scopus)

• Identification of Klebsiella capsule synthesis loci from whole genome data

  Wyres, K. L., Wick, R. R., Gorrie, C., Jenney, A., Follador, R., Thomson, N. R. & Holt, K. E., 1 Dec 2016, In: Microbial Genomics. 2, 12, 15 p., e000102.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  148 Citations (Scopus)

• Klebsiella pneumoniae Population Genomics and Antimicrobial-Resistant Clones

  Wyres, K. L. & Holt, K. E., 1 Dec 2016, In: Trends in Microbiology. 24, 12, p. 944-956 13 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  89 Citations (Scopus)

• Paradoxical Hypersusceptibility of Drug-resistant Mycobacterium tuberculosis to β-lactam Antibiotics

  Cohen, K. A., El-Hay, T., Wyres, K. L., Weissbrod, O., Munsamy, V., Yanover, C., Aharonov, R., Shaham, O., Conway, T. C., Goldschmidt, Y., Bishai, W. R. & Pym, A. S., 1 Jan 2016, In: EBioMedicine. 9, p. 170-179 10 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  17 Citations (Scopus)

• The diversity of Klebsiella pneumoniae surface polysaccharides

  Follador, R., Heinz, E., Wyres, K. L., Ellington, M. J., Kowarik, M., Holt, K. E. & Thomson, N. R., 1 Aug 2016, In: Microbial Genomics. 2, 8, 15 p., e000073.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  67 Citations (Scopus)
• 2015

  A platform for leveraging next generation sequencing for routine microbiology and public health use

  Rusu, L. I., Wyres, K. L., Reumann, M., Queiroz, C., Bojovschi, A., Conway, T., Garg, S. K., Edwards, D. J., Hogg, G. G. & Holt, K. E., Dec 2015, In: Health Information Science and Systems. 3, 1, 7 p., S7.

  Research output: Contribution to journal › Article › Other › peer-review

  Open Access

  File

• Extensive capsule locus variation and large-scale genomic recombination within the Klebsiella pneumoniae clonal group 258

  Wyres, K. L., Gorrie, C., Edwards, D. J., Wertheim, H. F. L., Hsu, L. Y., Van Kinh, N., Zadoks, R., Baker, S. & Holt, K. E., 1 Jan 2015, In: Genome Biology and Evolution. 7, 5, p. 1267-1279 13 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  55 Citations (Scopus)
• 2014

  Spatio-temporal information and knowledge representation of disease incidence and respective intervention strategies

  Davis, M., Von Cavallar, S., Wyres, K. L., Reumann, M., Sepulveda, M. J. & Rogers, P., 1 Jan 2014, e-Health - For Continuity of Care - Proceedings of MIE 2014. Pape-Haugaard, L., Seroussi Brigitte, B., Saka, O., Lovis, C., Hasman, A. & Andersen, S. K. (eds.). IOS Press, p. 1173-1177 5 p. (Studies in Health Technology and Informatics; vol. 205).

  Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

• Streptococcus pneumoniae carriage prevalence in Nepal: Evaluation of a method for delayed transport of samples from remote regions and implications for vaccine implementation

  Hanieh, S., Hamaluba, M., Kelly, D. F., Metz, J. A., Wyres, K. L., Fisher, R., Pradhan, R., Shakya, D., Shrestha, L., Shrestha, A., Joshi, A., Habens, J., Maharjan, B. D., Thorson, S., Bohler, E., Yu, L. M., Kelly, S., Plested, E., John, T., Werno, A. M. & 4 others, Adhikari, N., Murdoch, D. R., Brueggemann, A. B. & Pollard, A. J., 6 Jun 2014, In: PLoS ONE. 9, 6, 9 p., e98739.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

• WGS analysis and interpretation in clinical and public health microbiology laboratories: What are the requirements and how do existing tools compare?

  Wyres, K. L., Conway, T. C., Garg, S., Queiroz, C., Reumann, M., Holt, K. & Rusu, L. I., 11 Jun 2014, In: Pathogens. 3, 2, p. 437-458 22 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access

  File
  31 Citations (Scopus)
• 2013

  Evidence of antimicrobial resistance-conferring genetic elements among pneumococci isolated prior to 1974

  Wyres, K. L., van Tonder, A., Lambertsen, L. M., Hakenbeck, R., Parkhill, J., Bentley, S. D. & Brueggemann, A. B., 24 Jul 2013, In: BMC Genomics. 14, 1, 500.

  Research output: Contribution to journal › Article › Research › peer-review
  26 Citations (Scopus)

• Pneumococcal capsular switching: A historical perspective

  Wyres, K. L., Lambertsen, L. M., Croucher, N. J., McGee, L., Von Gottberg, A., Liñares, J., Jacobs, M. R., Kristinsson, K. G., Beall, B. W., Klugman, K. P., Parkhill, J., Hakenbeck, R., Bentley, S. D. & Brueggemann, A. B., 1 Feb 2013, In: Journal of Infectious Diseases. 207, 3, p. 439-449 11 p.

  Research output: Contribution to journal › Article › Research › peer-review
  107 Citations (Scopus)
• 2012

  The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success

  Wyres, K. L., Lambertsen, L. M., Croucher, N. J., McGee, L., von Gottberg, A., Liñares, J., Jacobs, M. R., Kristinsson, K. G., Beall, B. W., Klugman, K. P., Parkhill, J., Hakenbeck, R., Bentley, S. D. & Brueggemann, A. B., 16 Nov 2012, In: Genome Biology. 13, 11, R103.

  Research output: Contribution to journal › Article › Research › peer-review
  37 Citations (Scopus)
• 2010

  Environmental factors determining the epidemiology and population genetic structure of the bacillus cereus group in the field

  Raymond, B., Wyres, K. L., Sheppard, S. K., Ellis, R. J. & Bonsall, M. B., 1 May 2010, In: PLoS Pathogens. 6, 5, p. 1-13 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  57 Citations (Scopus)