Katie Flanagan

Assoc Professor

19992019
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Research Output 1999 2019

2019

The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility

Vemuri, R., Sylvia, K. E., Klein, S. L., Forster, S. C., Plebanski, M., Eri, R. & Flanagan, K. L., 15 Mar 2019, In : Seminars in Immunopathology. 41, 2, p. 265-275 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2017

Manipulating the microbiota to improve human health throughout life

Tran, J., Wilson, K., Plebanski, M. & Flanagan, K. L., 1 Sep 2017, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 111, 9, p. 379-381 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access

Measles Vaccination Is Effective at Under Nine Months of Age, and Provides Nonspecific Immunological Benefits

Flanagan, K. L., 15 Apr 2017, In : Journal of Infectious Diseases. p. 177-178 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Minimal sex-differential modulation of reactivity to pathogens and toll-like receptor ligands following infant Bacillus Calmette-Guérin Russia vaccination

Darboe, F., Adetifa, J. U., Reynolds, J., Hossin, S., Plebanski, M., Netea, M. G., Rowland-Jones, S. L., Sutherland, J. S. & Flanagan, K. L., 8 Sep 2017, In : Frontiers in Immunology. 8, SEP, 1092.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Negative correlation between circulating Cd4+Foxp3+Cd127 regulatory T Cells and subsequent antibody responses to infant measles vaccine but not diphtheria–tetanus–pertussis vaccine implies a regulatory role

Ndure, J., Noho-Konteh, F., Adetifa, J. U., Cox, M., Barker, P. F., Le, M. T., Sanyang, L. C., Drammeh, A., Whittle, H. C., Clarke, E., Plebanski, M., Rowland-Jones, S. L. & Flanagan, K. L., 14 Aug 2017, In : Frontiers in Immunology. 8, AUG, 12 p., 921.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Sex and gender differences in the outcomes of vaccination over the life course

Flanagan, K. L., Fink, A. L., Plebanski, M. & Klein, S. L., 6 Oct 2017, In : Annual Review of Cell and Developmental Biology. 33, p. 577-599 23 p.

Research output: Contribution to journalArticleResearchpeer-review

Sex-differential heterologous (non-specific) effects of vaccines: an emerging public health issue that needs to be understood and exploited

Flanagan, K. L. & Plebanski, M., 2 Jan 2017, In : Expert Review of Vaccines. 16, 1, p. 5-13 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The Economics of Malaria Vaccine Development

Plebanski, M. & Flanagan, K. L., 1 Mar 2017, In : Trends in Parasitology. 33, 3, p. 154-156 3 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

Bliss, C. M., Drammeh, A., Bowyer, G., Sanou, G. S., Jagne, Y. J., Ouedraogo, O., Edwards, N. J., Tarama, C., Ouedraogo, N., Ouedraogo, M., Njie-jobe, J., Diarra, A., Afolabi, M. O., Tiono, A. B., Yaro, J. B., Adetifa, U. J., Hodgson, S. H., Anagnostou, N. A., Roberts, R., Duncan, C. J. A. & 12 othersCortese, R., Viebig, N. K., Leroy, O., Lawrie, A. M., Flanagan, K. L., Kampmann, B., Imoukhuede, E. B., Sirima, S. B., Bojang, K. A., Hill, A. V. S., Nébié, I. & Ewer, K. J., 1 Feb 2017, In : Molecular Therapy. 25, 2, p. 547-559 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2016

Changing oral vaccine to inactivated polio vaccine might increase mortality

Fish, E. N., Flanagan, K. L., Furman, D., Klein, S. L., Kollmann, T. R., Jeppesen, D. L., Levy, O., Marchant, A., Namachivayam, S., Netea, M. G., Plebanski, M., Rowland-Jones, S. L., Selin, L. K., Shann, F. & Whittle, H. C., 12 Mar 2016, In : The Lancet. 387, 10023, p. 1054-1055 2 p.

Research output: Contribution to journalLetterOtherpeer-review

Polymorphism in liver-stage malaria vaccine candidate proteins: Immune evasion and implications for vaccine design

Flanagan, K. L., Wilson, K. L. & Plebanski, M., 3 Mar 2016, In : Expert Review of Vaccines. 15, 3, p. 389-399 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants

Afolabi, M. O., Tiono, A. B., Adetifa, U. J., Yaro, J. B., Drammeh, A., Nébié, I., Bliss, C. M., Hodgson, S. H., Anagnostou, N. A., Sanou, G. S., Jagne, Y. J., Ouedraogo, O., Tamara, C., Ouedraogo, N., Ouedraogo, M., Njie-jobe, J., Diarra, A., Duncan, C. J. A., Cortese, R., Nicosia, A. L. & 12 othersRoberts, R., Viebig, N. K., Leroy, O., Lawrie, A. M., Flanagan, K. L., Kampman, B., Bejon, P. A., Imoukhuede, E. B., Ewer, K. J., Hill, A. V. S., Bojang, K. A. & Sirima, S. B., 1 Aug 2016, In : Molecular Therapy. 24, 8, p. 1470-1477 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Sex differences in immune responses

Klein, S. L. & Flanagan, K. L., 1 Oct 2016, In : Nature Reviews Immunology. 16, 10, p. 626-638 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Sex-differential non-vaccine-specific immunological effects of diphtheria-tetanus-pertussis and measles vaccination

Noho-Konteh, F., Adetifa, J. U., Cox, M., Hossin, S., Reynolds, J., Le, M. T., Sanyang, L. C., Drammeh, A., Plebanski, M., Forster, T., Dickinson, P., Ghazal, P., Whittle, H., Rowland-Jones, S. L., Sutherland, J. S. & Flanagan, K. L., 1 Nov 2016, In : Clinical Infectious Diseases. 63, 9, p. 1213-1226 14 p.

Research output: Contribution to journalArticleResearchpeer-review

The global challenge and future strategies for keeping the world's aging population healthy by vaccination

Steeper, M., Plebanski, M. & Flanagan, K. L., 1 Aug 2016, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 110, 8, p. 427-431 5 p., trw054.

Research output: Contribution to journalEditorialOtherpeer-review

Timing of routine infant vaccinations and risk of food allergy and eczema at one year of age

Kiraly, N. J., Koplin, J., Crawford, N. W., Bannister, S., Flanagan, K. L., Holt, P., Gurrin, L. C., Lowe, A. J., Tang, M. L. K., Wake, M., Ponsonby, A. L., Dharmage, S. C. & Allen, K. J., 1 Apr 2016, In : Allergy. 71, 4, p. 541-549 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Early virological and immunological events in asymptomatic Epstein-Barr virus infection in African children

Jayasooriya, S. D., de Silva, T. I., Njie-jobe, J., Sanyang, C., Leese, A. M., Bell, A. I., McAulay, K. A., Peng, Y., Long, H. M., Dong, T., Whittle, H. C., Rickinson, A. B., Rowland-Jones, S. L., Hislop, A. D. & Flanagan, K. L., 2015, In : PLoS Pathogens. 11, 3, p. 1 - 18 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Heterologous and sex differential effects of administering vitamin A supplementation with vaccines

Jensen, K. J., Ndure, J., Plebanski, M. & Flanagan, K. L., 2015, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 109, 1, p. 36-45 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Heterologous immunological effects of early BCG vaccination in low-birth-weight infants in Guinea-Bissau: a randomized-controlled trial

Jensen, K. J., Larsen, N., Sorensen, S. B., Andersen, A. B., Eriksen, H. B., Monteiro, I., Hougaard, D. M., Aaby, P., Netea, M. G., Flanagan, K. L. & Benn, C. S., 2015, In : Journal of Infectious Diseases. 211, 6, p. 956 - 967 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Sex differences in outcomes of infections and vaccinations in under five-year-old children

Flanagan, K. L. & Jensen, K. J., 8 Aug 2015, Sex and Gender Differences in Infection and Treatments for Infectious Diseases. Cham Switzerland: Springer, p. 273-312 40 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Vaccines have sex differential non-targeted heterologous effects: A new dawn in vaccine research

Flanagan, K. L., Jan 2015, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 109, 1, p. 1-2 2 p., tru188.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Whole blood gene expression profiling of neonates with confirmed bacterial sepsis

Dickinson, P., Smith, C. L., Forster, T., Craigon, M. H., Ross, A. J., Khondoker, M. R., Ivens, A. C., Lynn, D. J., Orme, J., Jackson, A. D., Lacaze, P. A., Flanagan, K. L., Stenson, B. J. & Ghazal, P., 2015, In : Genomics Data. 3, p. 41 - 48 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

A double blind randomized controlled trial in neonates to determine the effect of vitamin A supplementation on immune responses: The Gambia protocol

McDonald, S. L. R., Savy, M., Fulford, A. J. C., Kendall, L., Flanagan, K. L. & Prentice, A. M., 2014, In : BMC Pediatrics. 14, 1, p. 1 - 8 8 p.

Research output: Contribution to journalArticleOther

Factors affecting immunogenicity of BCG in infants, a study in Malawi, The Gambia and the UK

Hur, Y-G., Gorak-Stolinska, P., Lalor, M. K., Mvula, H., Floyd, S., Raynes, J., Ben-Smith, A., Fitchett, J. R., Flanagan, K. L., Burl, S., Ota, M. O., Crampin, A. C., Smith, S. G. & Dockrell, H. M., 2014, In : BMC Infectious Diseases. 14, 1 (Art. No.: 184), p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Haematological and biochemical reference values of Gambian infants

Odutola, A. A., Afolabi, M. O., Jafali, J., Baldeh, I., Owolabi, O. A., Owiafe, P., Bah, G., Jaiteh, B., Mohammed, N. I., Donkor, S. A., Ndure, J., Adetifa, J. U., Flanagan, K. L. & Ota, M. O. C., Mar 2014, In : Tropical Medicine and International Health. 19, 3, p. 275-283 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Identification of a human neonatal immune-metabolic network associated with bacterial infection

Smith, C. L., Dickinson, P., Forster, T., Craigon, M. H., Ross, A. J., Khondoker, M. R., France, R., Ivens, A. C., Lynn, D. J., Orme, J., Jackson, A. D., Lacaze, P. A., Flanagan, K. L., Stenson, B. J. & Ghazal, P., 2014, In : Nature Communications. 5, Art. ID: 4649, p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Protection versus pathology in aviremic and high viral load HIV-2 infection-the pivotal role of immune activation and T-cell kinetics

Hegedus, A., Nyamweya, S., Zhang, Y., Govind, S., Aspinall, R. J., Mashanova, A., Jansen, V. A. A., Whittle, H. C., Jaye, A. B., Flanagan, K. L. & Macallan, D. C., 2014, In : Journal of Infectious Diseases. 210, 5, p. 752 - 761 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Randomized trial: The effect of oral polio vaccine at birth on polio antibody titers at 6 weeks and 6 months of age

Hansen, A. S., Lund, N., Flanagan, K. L., Rodrigues, A., Njie-jobe, J., Sanyang, L. C., Salanti, A., Andersen, A. B., Aaby, P., Benn, C. S. & Whittle, H. C., 2014, In : Trials in Vaccinology. 3, 1, p. 33-39 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Sexual dimorphism in biomedical research: A call to analyse by sex

Flanagan, K. L., 1 Jul 2014, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 108, 7, p. 385-387 3 p., tru079.

Research output: Contribution to journalEditorialOtherpeer-review

Targeting regulatory T cells to improve vaccine immunogenicity in early life

Ndure, J. & Flanagan, K. L., 2014, In : Frontiers in Microbiology. 5, Art. No.: 477, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations

Kimani, D., Jagne, Y. J., Cox, M., Kimani, E. N., Bliss, C. M., Gitau, E. N., Ogwang, C., Afolabi, M. O., Bowyer, G., Collins, K. A., Edwards, N. J., Hodgson, S. H., Duncan, C. J. A., Spencer, A. J., Knight, M. G., Drammeh, A., Anagnostou, N. A., Berrie, E. M., Moyle, S., Gilbert, S. C. & 16 othersSoipei, P., Okebe, J. U., Colloca, S., Cortese, R., Viebig, N. K., Roberts, R., Lawrie, A. M., Nicosia, A. L., Imoukhuede, E. B., Bejon, P. A., Chilengi, R., Bojang, K. A., Flanagan, K. L., Hill, A. V. S., Urban, B. & Ewer, K. J., 2014, In : Molecular Therapy. 22, 11, p. 1992 - 2003 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

A Phase I Randomized Clinical Trial of Candidate Human Immunodeficiency Virus type 1 Vaccine MVA.HIVA Administered to Gambian Infants

Afolabi, M. O., Ndure, J., Drammeh, A., Darboe, F., Mehedi, S. R., Rowland-Jones, S. L., Borthwick, N., Black, A., Ambler, G., John-Stewart, G. C., Reilly, M., Hanke, T. & Flanagan, K. L., 24 Oct 2013, In : PLoS ONE. 8, 10, 10 p., e78289.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Comparing HIV-1 and HIV-2 infection: Lessons for viral immunopathogenesis

Nyamweya, S., Hegedus, A., Jaye, A. B., Rowland-Jones, S. L., Flanagan, K. L. & Macallan, D. C., Jul 2013, In : Reviews in Medical Virology. 23, 4, p. 221-240 20 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Heterologous ("nonspecific") and sex-differential effects of vaccines: epidemiology, clinical trials, and emerging immunologic mechanisms

Flanagan, K. L., van Crevel, R., Curtis, N., Shann, F. & Levy, O., 2013, In : Clinical Infectious Diseases. 57, 2, p. 283 - 289 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Impaired Th1 immunity in ovarian cancer patients is mediated by TNFR2+ Tregs within the tumor microenvironment

Govindaraj, C., Scalzo-Inguanti, K., Madondo, M., Halo, J., Flanagan, K. L., Quinn, M. & Plebanski, M., 2013, In : Clinical Immunology. 149, 1, p. 97 - 110 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Prevalence of infestation with gastrointestinal nematodes in Pony Club horses in Victoria

Flanagan, K. L., Morton, J. M. & Sandeman, R. M., 2013, In : Australian Veterinary Journal. 91, 6, p. 241 - 245 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults

Ogwang, C., Afolabi, M. O., Kimani, D., Jagne, Y. J., Sheehy, S. H., Bliss, C. M., Duncan, C. J. A., Collins, K. A., Garcia Knight, M. A., Kimani, E. N., Anagnostou, N. A., Berrie, E. M., Moyle, S., Gilbert, S. C., Spencer, A. J., Soipei, P., Mueller, J., Okebe, J. U., Colloca, S., Cortese, R. & 1 othersFlanagan, K. L., 19 Mar 2013, In : PLoS ONE. 8, 3, 11 p., e57726.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Transcriptional profiling technology for studying vaccine responses: an untapped goldmine

Flanagan, K. L., Noho-Konteh, F., Ghazal, P. & Dickinson, P., 2013, In : Methods. 60, 3, p. 269 - 274 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Are plasma biomarkers of immune activation predictive of HIV progression: A longitudinal comparison and analyses in HIV-1 and HIV-2 infections?

Nyamweya, S., Townend, J., Zaman, A., Steele, S. J., Jeffries, D., Rowland-Jones, S. L., Whittle, H. C., Flanagan, K. L. & Jaye, A. B., 10 Sep 2012, In : PLoS ONE. 7, 9, 11 p., e44411.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Immunological impact of an additional early measles vaccine in Gambian children: Responses to a boost at 3 years

Njie-jobe, J., Nyamweya, S., Miles, D. J. C., van der Sande, M., Zaman, S., Touray, E., Hossin, S., Adetifa, J. U., Palmero, M., Burl, S., Jeffries, D., Rowland-Jones, S. L., Flanagan, K., Jaye, A. B. & Whittle, H. C., 28 Mar 2012, In : Vaccine. 30, 15, p. 2543-2550 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients

Ahuja, S. D., Ashkin, D., Avendano, M., Banerjee, R., Bauer, M., Bayona, J. N., Becerra, M. C., Benedetti, A., Burgos, M., Centis, R., Chan, E. D., Chiang, C. Y., Cox, H., D'Ambrosio, L., DeRiemer, K., Dung, N. H., Enarson, D., Falzon, D., Flanagan, K., Flood, J. & 52 othersGarcia-Moliner, M. L., Gandhi, N., Granich, R. M., Hollm-Delgado, M. G., Holtz, T. H., Iseman, M. D., Jarlsberg, L. G., Keshavjee, S., Kim, H. R., Koh, W. J., Lancaster, J., Lange, C., de Lange, W. C. M., Leimane, V., Leung, C. C., Li, J., Menzies, D., Migliori, G-B., Mishustin, S. P., Mitnick, C. D., Narita, M., O'Riordan, P., Pai, M., Palmero, D., Park, S. K., Pasvol, G., Peña, J., Pérez-Guzmán, C., Quelapio, M. I. D., Ponce-de-Leon, A., Riekstina, V., Robert, J., Royce, S., Schaaf, H. S., Seung, K. J., Shah, L., Shim, T. S., Shin, S. S., Shiraishi, Y., Sifuentes-Osornio, J., Sotgiu, G., Strand, M. J., Tabarsi, P., Tupasi, T. E., van Altena, R., van der Walt, M., van der Werf, T. S., Vargas, M. H., Viiklepp, P., Westenhouse, J., Yew, W. W. & Yim, J. J., Aug 2012, In : PLoS Medicine. 9, 8, e1001300.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Placental malaria is associated with attenuated CD4 T-cell responses to tuberculin PPD 12 months after BCG vaccination

Walther, B., Miles, D. J. C., Waight, P., Palmero, M. S., Ojuola, O., Touray, E. S., Whittle, H. C., van der Sande, M., Crozier, S. & Flanagan, K. L., 14 Jan 2012, In : BMC Infectious Diseases. 12, 6, 7 p., 6.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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T-cell immunity to Kaposi sarcoma-associated herpesvirus: Recognition of primary effusion lymphoma by LANA-specific CD4 + T cells

Sabbah, S., Jagne, Y. J., Zuo, J., de Silva, T. I., Ahasan, M. M., Brander, C., Rowland-Jones, S. L., Flanagan, K. L. & Hislop, A. D., 1 Mar 2012, In : Blood. 119, 9, p. 2083-2092 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

The challenge of assessing infant vaccine responses in resource-poor settings

Flanagan, K. L., Burl, S., Lohman-Payne, B. L. & Plebanski, M., Jun 2010, In : Expert Review of Vaccines. 9, 6, p. 665-674 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2008

Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4+ CD25high T cells with susceptibility in Kenyans

Todryk, S. M., Bejon, P., Mwangi, T., Plebanski, M., Urban, B., Marsh, K., Hill, A. V. S. & Flanagan, K. L., 2008, In : PLoS ONE. 3, 4 (e2027), p. 1 - 7 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Predicting memory: a prospective readout for malaria vaccines?

Minigo, G., Scalzo, K., Flanagan, K. L. & Plebanski, M., 2007, In : Trends in Parasitology. 23, 8, p. 341 - 343 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Cellular reactivity to the p. Falciparum protein trap in adult kenyans: Novel epitopes, complex cytokine patterns, and the impact of natural antigenic variation

Flanagan, K. L., Plebanski, M., Odhiambo, K., Sheu, E., Mwangi, T., Gelder, C., Hart, K., Kortok, M., Lowe, B., Robson, K. J., Marsh, K. & Hill, A. V. S., 2006, In : American Journal of Tropical Medicine and Hygiene. 74, 3, p. 367 - 375 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Dimorphic Plasmodium falciparum merozoite surface protein-1 epitopes turn off memory T cells and interfere with T cell priming

Lee, E. A. M., Flanagan, K. L., Minigo, G., Reece, W. H., Bailey, R., Pinder, M., Hill, A. V. S. & Plebanski, M., 2006, In : European Journal of Immunology. 36, 5, p. 1168 - 1178 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

Direct processing and presentation of antigen from malaria sporozoites by professional antigen-presenting cells in the induction of CD8+ T-cell responses

Plebanski, M., Hannan, C. M., Behboudi, S., Flanagan, K. L., Apostolopoulos, V., Sinden, R. E. & Hill, A. V. S., Jun 2005, In : Immunology and Cell Biology. 83, 3, p. 307-312 6 p.

Research output: Contribution to journalArticleResearchpeer-review