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Research Output 2012 2018

2018

Apoptosis in megakaryocytes and platelets: the life and death of a lineage

McArthur, K., Chappaz, S. & Kile, B. T., 8 Feb 2018, In : Blood. 131, 6, p. 605-610 6 p.

Research output: Contribution to journalArticleOtherpeer-review

Apoptotic Caspases: Multiple or Mistaken Identities?

McArthur, K. & Kile, B. T., 1 Jun 2018, In : Trends in Cell Biology. 28, 6, p. 475-493 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

McArthur, K., Whitehead, L. W., Heddleston, J. M., Li, L., Padman, B. S., Oorschot, V., Geoghegan, N. D., Chappaz, S., Davidson, S., Chin, H. S., Lane, R. M., Dramicanin, M., Saunders, T. L., Sugiana, C., Lessene, R., Osellame, L. D., Chew, T. L., Dewson, G., Lazarou, M., Ramm, G. & 5 othersLessene, G., Ryan, M. T., Rogers, K. L., Van Delft, M. F. & Kile, B. T., 23 Feb 2018, In : Science. 359, 6378, 12 p., eaao6047.

Research output: Contribution to journalArticleResearchpeer-review

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

Vince, J. E., De Nardo, D., Gao, W., Vince, A. J., Hall, C., McArthur, K., Simpson, D., Vijayaraj, S., Lindqvist, L. M., Bouillet, P., Rizzacasa, M. A., Man, S. M., Silke, J., Masters, S. L., Lessene, G., Huang, D. C. S., Gray, D. H. D., Kile, B. T., Shao, F. & Lawlor, K. E., 27 Nov 2018, In : Cell Reports. 25, 9, p. 2339-2353 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017

Activation of cGAS-dependent antiviral responses by DNA intercalating agents

Pepin, G., Nejad, C., Thomas, B. J., Ferrand, J., McArthur, K., Bardin, P. G., Williams, B. R. G. & Gantier, M. P., 9 Jan 2017, In : Nucleic Acids Research. 45, 1, p. 198-205 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion

Lindqvist, L. M., Frank, D., McArthur, K., Dite, T. A., Lazarou, M., Oakhill, J. S., Kile, B. T. & Vaux, D. L., 11 Dec 2017, In : Cell Death and Differentiation. 25, p. 782-794 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia

McArthur, K., D'Cruz, A., Segal, D., Lackovic, K., Wilks, A. F., O'Donnell, J. A., Nowell, C. J., Gerlic, M., Huang, D. C. S., Burns, C. J. & Croker, B. A., 2017, In : Oncotarget. 8, 35, p. 57948-57963 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The reinvention of twentieth century microscopy for three-dimensional imaging

Whitehead, L. W., McArthur, K., Geoghegan, N. D. & Rogers, K. L., 1 Jul 2017, In : Immunology and Cell Biology. 95, 6, p. 520-524 5 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

2014

Apoptotic caspases suppress mtDNA-induced STING-mediated type i IFN production

White, M. J., McArthur, K., Metcalf, D., Lane, R. M., Cambier, J. C., Herold, M. J., van Delft, M. F., Bedoui, S., Lessene, G., Ritchie, M. E., Huang, D. C. S. & Kile, B. T., 18 Dec 2014, In : Cell. 159, 7, p. 1549-1562 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2012

IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3

Croker, B. A., Kiu, H., Pellegrini, M., Toe, J., Preston, S., Metcalf, D., O'Donnell, J. A., Cengia, L. H., McArthur, K., Nicola, N. A., Alexander, W. S. & Roberts, A. W., Jan 2012, In : Immunology and Cell Biology. 90, 1, p. 124-129 6 p.

Research output: Contribution to journalArticleResearchpeer-review

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells

Masters, S. L., Gerlic, M., Metcalf, D., Preston, S., Pellegrini, M., O'Donnell, J. A., McArthur, K., Baldwin, T. M., Chevrier, S., Nowell, C. J., Cengia, L. H., Henley, K. J., Collinge, J. E., Kastner, D. L., Feigenbaum, L., Hilton, D. J., Alexander, W. S., Kile, B. T. & Croker, B. A., 14 Dec 2012, In : Immunity. 37, 6, p. 1009-1023 15 p.

Research output: Contribution to journalArticleResearchpeer-review