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Personal profile

External positions

Visiting Scientist, The Walter and Eliza Hall Institute of Medical Research (WEHI)

1 Jan 201831 Dec 2018

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2020 2022

Research Output 2012 2019

1 Citation (Scopus)

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

van Delft, M. F., Chappaz, S., Khakham, Y., Bui, C. T., Debrincat, M. A., Lowes, K. N., Brouwer, J. M., Grohmann, C., Sharp, P. P., Dagley, L. F., Li, L., McArthur, K., Luo, M. X., Chin, H. S., Fairlie, W. D., Lee, E. F., Segal, D., Duflocq, S., Lessene, R., Bernard, S. & 16 others, Peilleron, L., Nguyen, T., Miles, C., Wan, S. S., Lane, R. M., Wardak, A., Lackovic, K., Colman, P. M., Sandow, J. J., Webb, A. I., Czabotar, P. E., Dewson, G., Watson, K. G., Huang, D. C. S., Lessene, G. & Kile, B. T., 1 Nov 2019, In : Nature Chemical Biology. 15, 11, p. 1057-1066 10 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Apoptosis in megakaryocytes and platelets: the life and death of a lineage

McArthur, K., Chappaz, S. & Kile, B. T., 8 Feb 2018, In : Blood. 131, 6, p. 605-610 6 p.

Research output: Contribution to journalArticleOtherpeer-review

25 Citations (Scopus)

Apoptotic Caspases: Multiple or Mistaken Identities?

McArthur, K. & Kile, B. T., 1 Jun 2018, In : Trends in Cell Biology. 28, 6, p. 475-493 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

63 Citations (Scopus)

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

McArthur, K., Whitehead, L. W., Heddleston, J. M., Li, L., Padman, B. S., Oorschot, V., Geoghegan, N. D., Chappaz, S., Davidson, S., Chin, H. S., Lane, R. M., Dramicanin, M., Saunders, T. L., Sugiana, C., Lessene, R., Osellame, L. D., Chew, T. L., Dewson, G., Lazarou, M., Ramm, G. & 5 others, Lessene, G., Ryan, M. T., Rogers, K. L., Van Delft, M. F. & Kile, B. T., 23 Feb 2018, In : Science. 359, 6378, 12 p., eaao6047.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

Vince, J. E., De Nardo, D., Gao, W., Vince, A. J., Hall, C., McArthur, K., Simpson, D., Vijayaraj, S., Lindqvist, L. M., Bouillet, P., Rizzacasa, M. A., Man, S. M., Silke, J., Masters, S. L., Lessene, G., Huang, D. C. S., Gray, D. H. D., Kile, B. T., Shao, F. & Lawlor, K. E., 27 Nov 2018, In : Cell Reports. 25, 9, p. 2339-2353 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Prizes

In Memory of Neil Lawrence Prize, 2018 Centenary Institute Medical Innovation Award

Kate McArthur (Recipient), 3 Oct 2018

Prize: Prize (including medals and awards)

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Press / Media

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

Benjamin Thomas Kile & Kate McArthur

24/02/1823/08/18

2 items of Media coverage, 1 Media contribution

Press/Media: Research