Projects per year
Personal profile
Biography
Kate Leslie studied medicine at the University of Melbourne and undertook anaesthesia training in Melbourne and San Francisco, achieving Fellowship of the Australian and New Zealand College of Anaesthetists in March 1993. After another year in San Francisco, she returned to Melbourne to a full-time specialist staff role at the Royal Melbourne Hospital (RMH). Leslie is now Head of Research in the Department of Anaesthesia and Pain Management at RMH. Her clinical interests include anaesthesia for neurosurgery, colorectal and trauma surgery, and sedation for gastrointestinal endoscopy. She is an Honorary Professorial Fellow in the Anaesthesia Perioperative and Pain Medicine Unit, Melbourne Medical School, and Department of Pharmacology and Therapeutics, University of Melbourne, and Honorary Adjunct Professor, Department of Epidemiology and Preventive Medicine, Monash University.
Leslie’s involvement in clinical research began after she passed the ANZCA primary examination in 1988. She published several studies as a trainee, under the mentorship of Drs David Crankshaw, Brendan Silbert and Daniel Sessler. It was under Dr Sessler’s guidance at the University of California, San Francisco, she developed interests in thermoregulation, depth of anaesthesia monitoring and awareness.
On return to Australia, Leslie completed a Doctor of Medicine and a Master of Epidemiology. Since 1989, she has published more than 180 peer-reviewed publications, as well as four book chapters. She has made more than 300 invited presentations at international, national and local meetings, and been the Australasian Visitor to the ANZCA Annual Scientific Meeting twice.
She is on the editorial board of Anesthesia and Analgesia, the British Journal of Anaesthesia and Anesthesiology. She is one of the six editors of Miller’s Anesthesia (9th edition), and has won the ASA/Boots Young Investigator Award, the ASA’s Gilbert Troup Medal, the ANZCA Gilbert Brown Prize and the ANZCA Douglas Joseph Professorship.
Leslie first became involved with multi-centre research with the B-Aware trial, a 2,500 patient multi-centre trial on awareness. She was/is also a chief investigator of the ENIGMA-I, ENIGMA-II, POISE-1, POISE-2, POISE-3, Balanced, RELIEF, PADDI, ROCKet and Chewy studies.
Leslie’s involvement with ANZCA began when she was co-opted as the New Fellow on the Victorian Regional Committee in 1994. She served on the VRC until 2002. In that same year, she was elected to Council. Leslie was a Primary Examiner for six years, and Scientific Convenor of the Annual Scientific Meeting held in Melbourne in 2000. During her time on Council she served as Chair of the Communications and Fellowship Affairs, Research, Training Accreditation, Investments, IMGS and Executive Committees; ASM Officer; Honorary Treasurer; and Chair of the Anaesthesia and Pain Medicine Foundation Board, as well as numerous other committees and working groups.
In 2012, she was elected President and served a two year term. During this time she was also a member of the Committee of Presidents of Medical Colleges, and its chair from 2011-13. She is currently a director of the Australian Medical Council and chair of its Specialist Education Accreditation Committee.
Kate Leslie has received many accolades and honours during her career, including the Robert Orton Medal, the Melbourne Health Chairman’s Award, and fellowship of the Australian Academy of Health and Medical Research. She was appointed an Officer in the Order of Australia in 2016 and was the first anaesthetist to be honoured with a Doctor of Medical Science (Honoris Causa) by the University of Melbourne.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Anaesthesia
- Thermoregulation
- Anaesthesia monitoring
Collaborations and top research areas from the last five years
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LOLIPOP: The Long-term Outcomes of Lidocaine Infusions for persistent PostOperative Pain in patients undergoing breast surgery (LOLIPOP) Trial
Corcoran, T., Myles, P., Toner, A. J., Saunders, C., Forbes, A., Peyton, P., Leslie, K., Schug, S. A., Story, D. A. & Scott, D.
1/06/20 → 31/05/25
Project: Research
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Tranexamic acid and hypotension-avoidance to prevent death and major complications after noncardiac surgery (PeriOperative ISchemic Evaluation-3 – the POISE-3 Trial)
Leslie, K., Leslie, K., Painter, T., Devereaux, P. J., Peyton, P. J., Corcoran, T., Chan, M. T. V. & Short, T. G.
1/01/19 → 31/12/23
Project: Research
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Outcomes in males and females participating in large non-cardiac surgery studies
1/01/20 → 31/12/20
Project: Research
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Reduction Of Chronic Post-surgical Pain with Ketamine - ROCKet Study
Peyton, P. J., Leslie, K., Story, D. A., Myles, P., Chan, M. T. V., Schug, S. A., Evered, L. A. & Braat, S.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/17 → 31/12/22
Project: Research
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Perioperative Administration of Dexamethasone and Infection- The PADDI trial
Corcoran, T., Bach, L., Chan, M. T. V., Cheng, A., Forbes, A., Ho, K., Leslie, K., Myles, P. & Short, T.
National Health and Medical Research Council (NHMRC) (Australia)
1/11/15 → 31/07/21
Project: Research
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Perioperative oxygen administration in patients undergoing major non-cardiac surgery under general anaesthesia in Australia and New Zealand
Frei, D. R., Beasley, R., Campbell, D., Leslie, K., Merry, A., Moore, M., Myles, P. S., Ruawai-Hamilton, L., Short, T. G., Sibanda, N. & Young, P. J., 2023, (Accepted/In press) In: Anaesthesia and Intensive Care. p. 1-8 8 p.Research output: Contribution to journal › Article › Research › peer-review
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Postoperative Pulmonary Complications in the ENIGMA II Trial: A Post Hoc Analysis
Peyton, P. J., Liskaser, G., Ho, A., Marsh, H., Etherington, C., Torlot, F., Desai, M., Perrett, G., Chee, B., Leslie, K. & Myles, P. S., 1 Apr 2023, In: Anesthesiology. 138, 4, p. 354-363 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Core Outcome Measures for Perioperative and Anaesthetic Care (COMPAC): a modified Delphi process to develop a core outcome set for trials in perioperative care and anaesthesia
Boney, O., Moonesinghe, S. R., Myles, P. S., Grocott, M. P. W. & the StEP-COMPAC Group, Jan 2022, In: British Journal of Anaesthesia. 128, 1, p. 174-185 12 p.Research output: Contribution to journal › Article › Research › peer-review
21 Citations (Scopus) -
Dexamethasone and clinically significant postoperative nausea and vomiting: a prespecified substudy of the randomised perioperative administration of dexamethasone and infection (PADDI) trial
Corcoran, T. B., Martin, C., O'Loughlin, E., Ho, K. M., Coutts, P., Chan, M. T., Forbes, A., Leslie, K. & Myles, P., 1 Sept 2022, In: British Journal of Anaesthesia. 129, 3, p. 327-335 9 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial
Garg, A. X., Cuerden, M., Aguado, H., Amir, M., Belley-Cote, E. P., Bhatt, K., Biccard, B. M., Borges, F. K., Chan, M., Conen, D., Duceppe, E., Efremov, S., Eikelboom, J., Fleischmann, E., Giovanni, L., Gross, P., Jayaram, R., Kirov, M., Kleinlugtenbelt, Y., Kurz, A., & 36 others , Jan 2022, In: Canadian Journal of Kidney Health and Disease. 9, p. 1-9 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access