Projects per year
Personal profile
Biography
Dr Karla Hutt obtained her PhD from the Australian National University in 2006, where her studies focussed on the establishment and maintenance of the primordial follicle pool during ovarian development. She then undertook her postdoctoral studies at the University of Kansas Medical Center (USA), where she investigated the impact of environmental toxicants on oocyte and embryo quality. In 2008 she returned to Australia and to join Professor Jock Findlay's laboratory at Prince Henrys Institute (now the Hudson Institute of Medical Research). In 2015 she relocated to Monash University and leads the Ovarian Biology Laboratory. Her group investigates the role of DNA repair and apoptosis in determining oocyte number and quality, with the aim of i) improving women’s health and fertility during maternal aging and ii) developing new therapeutic strategies to protect female fertility during anti-cancer therapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- ovary
- oocyte
- follilce
- fertility
- apoptosis
- DNA repair
Collaborations and top research areas from the last five years
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Characterization of the Germline Regulatory Landscape
Pocock, R., Cao, W., Fan, Q., Hutt, K., Gopal, S., Schittenhelm, R., Hobbs, R., Archer, S. & Coutts, S.
1/01/23 → 31/12/27
Project: Research
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Survivorship Sequelae of Precision Breast Cancer Treatments: Defining the impacts of immunotherapy and PARP inhibitors on ovarian function and fertility
Hutt, K., Phillips, K. A., Loi, S., Winship, A. & Cui, W.
National Breast Cancer Foundation
23/03/22 → 31/12/24
Project: Research
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Does Chlamydia infection damage the ovary and compromise fertility?
Hutt, K., Beagley, K., Homer, H. A. & Carey, A.
1/01/22 → 31/12/26
Project: Research
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DNA repair: a critical quality control mechanism in the female germ line
Australian Research Council (ARC)
1/01/20 → 31/12/23
Project: Research
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SCIREQ inExpose system
Winship, A., Carroll, J., Bourke, J., Simonds, S., Heng, T., Hutt, K., Stringer, J., Western, P., Coelho Marques, F. & Abud, H.
1/10/21 → 31/12/22
Project: Research
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Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life
Stringer, J. M., Alesi, L. R., Winship, A. L. & Hutt, K. J., 5 Jul 2023, In: Human Reproduction Update. 29, 4, p. 434-456 23 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus) -
Impact of Chronic Multi-Generational Exposure to an Environmentally Relevant Atrazine Concentration on Testicular Development and Function in Mice
Kolaitis, N. D., Finger, B. J., Merriner, D. J., Nguyen, J., Houston, B. J., O’Bryan, M. K., Stringer, J. M., Zerafa, N., Nguyen, N., Hutt, K. J., Tarulli, G. A. & Green, M. P., Feb 2023, In: Cells. 12, 4, 18 p., 648.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
Griffiths, M. J., Higgins, J. N., Cousins, F. L., Alesi, L. R., Winship, A. L. & Hutt, K. J., Apr 2023, In: Journal of Visualized Experiments. 194, 14 p., e64763.Research output: Contribution to journal › Article › Other › peer-review
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Radiotherapy exposure directly damages the uterus and causes pregnancy loss
Griffiths, M. J., Marshall, S. A., Cousins, F. L., Alesi, L. R., Higgins, J., Giridharan, S., Sarma, U. C., Menkhorst, E., Zhou, W., Care, A. S., Donoghue, J. F., Holdsworth-Carson, S. J., Rogers, P. AW., Dimitriadis, E., Gargett, C. E., Robertson, S. A., Winship, A. L. & Hutt, K. J., 22 Mar 2023, In: JCI Insight. 8, 6, 21 p., e163704.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
The future of fertility preservation for women treated with chemotherapy
Alesi, L. R., Nguyen, Q-N., Stringer, J., Winship, A. & Hutt, K., 2023, In: Reproduction and Fertility. 4, 2, 22 p., e220123.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access