20062020
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Personal profile

Biography

Dr Karla Hutt obtained her PhD from the Australian National University in 2006, where her studies focussed on the establishment and maintenance of the primordial follicle pool during ovarian development. She then undertook her postdoctoral studies at the University of Kansas Medical Center (USA), where she investigated the impact of environmental toxicants on oocyte and embryo quality. In 2008 she returned to Australia and to join Professor Jock Findlay's laboratory at Prince Henrys Institute (now the Hudson Institute of Medical Research). In 2015 she relocated to Monash University and leads the Ovarian Biology Laboratory. Her group investigates the role of DNA repair and apoptosis in determining oocyte number and quality, with the aim of i) improving women’s health and fertility during maternal aging and ii) developing new therapeutic strategies to protect female fertility during anti-cancer therapy.

 

 

Keywords

  • ovary
  • oocyte
  • follilce
  • fertility
  • apoptosis
  • DNA repair

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Projects 2013 2020

Research Output 2006 2019

Cisplatin- and cyclophosphamide-induced primordial follicle depletion is caused by direct damage to oocytes

Nguyen, QN., Zerafa, N., Liew, J., Findlay, J. K., Hickey, M. & Hutt, K., 6 Apr 2019, (Accepted/In press) In : Molecular Human Reproduction. 30 p.

Research output: Contribution to journalArticleResearchpeer-review

Oocytes from stem cells

Sarma, U. C., Findlay, J. K. & Hutt, K. J., 1 Feb 2019, In : Best Practice & Research: Clinical Obstetrics & Gynaecology. 55, p. 14-22 9 p.

Research output: Contribution to journalArticleOtherpeer-review

Vincristine Chemotherapy Induces Atresia of Growing Ovarian Follicles in Mice

Winship, A. L., Carpenter, M., Griffiths, M. & Hutt, K. J., 1 May 2019, In : Toxicological sciences : an official journal of the Society of Toxicology. 169, 1, p. 43-53 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Dacarbazine depletes the ovarian reserve in mice and depletion is enhanced with age

Winship, A. L., Bakai, M., Sarma, U., Liew, S. H. & Hutt, K. J., 25 Apr 2018, In : Scientific Reports. 8, 1, 13 p., 6516.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Examination of the ovotoxicity of 5-fluorouracil in mice

Lambouras, M., Liew, S. H., Horvay, K., Abud, H. E., Stringer, J. M. & Hutt, K. J., Jun 2018, In : Journal of Assisted Reproduction and Genetics. 35, 6, p. 1053-1060 8 p.

Research output: Contribution to journalArticleResearchpeer-review