Projects per year
Personal profile
Biography
Dr Karla Hutt obtained her PhD from the Australian National University in 2006, where her studies focussed on the establishment and maintenance of the primordial follicle pool during ovarian development. She then undertook her postdoctoral studies at the University of Kansas Medical Center (USA), where she investigated the impact of environmental toxicants on oocyte and embryo quality. In 2008 she returned to Australia and to join Professor Jock Findlay's laboratory at Prince Henrys Institute (now the Hudson Institute of Medical Research). In 2015 she relocated to Monash University and leads the Ovarian Biology Laboratory. Her group investigates the role of DNA repair and apoptosis in determining oocyte number and quality, with the aim of i) improving women’s health and fertility during maternal aging and ii) developing new therapeutic strategies to protect female fertility during anti-cancer therapy.
Research area keywords
- ovary
- oocyte
- follilce
- fertility
- apoptosis
- DNA repair
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
DNA repair: a critical quality control mechanism in the female germ line
Australian Research Council (ARC)
1/01/20 → 31/01/23
Project: Research
Defining the epigenetic origins of maternally inherited disease.
Western, P., Gardner, D., Voss, A. K., van den Buuse, M., Adelson, D. L., Sims, N., Hutt, K., Dickinson, H., Stringer, J., Hill, R. & Gibson, W.
1/01/18 → 31/12/20
Project: Research
Exploring the DNA repair capacity of oocytes
Hutt, K., Scott, C. L. & Wakefield, M.
National Health & Medical Research Council (NHMRC)
1/01/16 → 30/06/19
Project: Research
The role of Bid in apoptosis within the ovary
Hutt, K. & Anderson, R.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/17
Project: Research
A novel strategy for fertility preservation in breast cancer patients
National Breast Cancer Foundation
1/01/14 → 31/12/15
Project: Research
Research Output
Do cancer therapies damage the uterus and compromise fertility?
Griffiths, M. J., Winship, A. L. & Hutt, K. J., Mar 2020, In : Human Reproduction Update. 26, 2, p. 161-173 13 p.Research output: Contribution to journal › Article › Research › peer-review
Moderate episodic prenatal alcohol does not impact female offspring fertility in rats
McReight, E. K., Liew, S. H., Steane, S. E., Hutt, K. J., Moritz, K. M. & Akison, L. K., May 2020, In : Reproduction. 159, 5, p. 615-626 12 p.Research output: Contribution to journal › Article › Research › peer-review
NMN does not protect the ovarian reserve from cancer treatments
Stringer, J., Groenewegen, E., Liew, S. H. & Hutt, K., Feb 2020, In : Reproduction. 159, 2, p. 105-113 9 p.Research output: Contribution to journal › Article › Research › peer-review
1
Citation
(Scopus)
Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health
Stringer, J. M., Winship, A., Zerafa, N., Wakefield, M. & Hutt, K., 26 May 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 21, p. 11513–11522 10 p.Research output: Contribution to journal › Article › Research › peer-review
The PARP inhibitor, olaparib, depletes the ovarian reserve in mice: implications for fertility preservation
Winship, A. L., Griffiths, M., Lliberos Requesens, C., Sarma, U., Phillips, K-A. & Hutt, K. J., 30 Jun 2020, (Accepted/In press) In : Human Reproduction. 11 p.Research output: Contribution to journal › Article › Research › peer-review