• 19 Innovation Walk

    3800 Clayton

20062020

Research output per year

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Personal profile

Biography

Dr Karla Hutt obtained her PhD from the Australian National University in 2006, where her studies focussed on the establishment and maintenance of the primordial follicle pool during ovarian development. She then undertook her postdoctoral studies at the University of Kansas Medical Center (USA), where she investigated the impact of environmental toxicants on oocyte and embryo quality. In 2008 she returned to Australia and to join Professor Jock Findlay's laboratory at Prince Henrys Institute (now the Hudson Institute of Medical Research). In 2015 she relocated to Monash University and leads the Ovarian Biology Laboratory. Her group investigates the role of DNA repair and apoptosis in determining oocyte number and quality, with the aim of i) improving women’s health and fertility during maternal aging and ii) developing new therapeutic strategies to protect female fertility during anti-cancer therapy.

 

 

Research area keywords

  • ovary
  • oocyte
  • follilce
  • fertility
  • apoptosis
  • DNA repair

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Projects

Research Output

Do cancer therapies damage the uterus and compromise fertility?

Griffiths, M. J., Winship, A. L. & Hutt, K. J., Mar 2020, In : Human Reproduction Update. 26, 2, p. 161-173 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Moderate episodic prenatal alcohol does not impact female offspring fertility in rats

McReight, E. K., Liew, S. H., Steane, S. E., Hutt, K. J., Moritz, K. M. & Akison, L. K., May 2020, In : Reproduction. 159, 5, p. 615-626 12 p.

Research output: Contribution to journalArticleResearchpeer-review

NMN does not protect the ovarian reserve from cancer treatments

Stringer, J., Groenewegen, E., Liew, S. H. & Hutt, K., Feb 2020, In : Reproduction. 159, 2, p. 105-113 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health

Stringer, J. M., Winship, A., Zerafa, N., Wakefield, M. & Hutt, K., 26 May 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 21, p. 11513–11522 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The PARP inhibitor, olaparib, depletes the ovarian reserve in mice: implications for fertility preservation

Winship, A. L., Griffiths, M., Lliberos Requesens, C., Sarma, U., Phillips, K-A. & Hutt, K. J., 30 Jun 2020, (Accepted/In press) In : Human Reproduction. 11 p.

Research output: Contribution to journalArticleResearchpeer-review