Projects per year
Personal profile
Biography
Dr Karla Hutt obtained her PhD from the Australian National University in 2006, where her studies focussed on the establishment and maintenance of the primordial follicle pool during ovarian development. She then undertook her postdoctoral studies at the University of Kansas Medical Center (USA), where she investigated the impact of environmental toxicants on oocyte and embryo quality. In 2008 she returned to Australia and to join Professor Jock Findlay's laboratory at Prince Henrys Institute (now the Hudson Institute of Medical Research). In 2015 she relocated to Monash University and leads the Ovarian Biology Laboratory. Her group investigates the role of DNA repair and apoptosis in determining oocyte number and quality, with the aim of i) improving women’s health and fertility during maternal aging and ii) developing new therapeutic strategies to protect female fertility during anti-cancer therapy.
Keywords
- ovary
- oocyte
- follilce
- fertility
- apoptosis
- DNA repair
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2020
Defining the epigenetic origins of maternally inherited disease.
Western, P., Gardner, D., Voss, A. K., van den Buuse, M., Adelson, D. L., Sims, N., Hutt, K., Dickinson, H., Stringer, J., Hill, R. & Gibson, W.
1/01/18 → 31/12/20
Project: Research
Exploring the DNA repair capacity of oocytes
Hutt, K., Scott, C. L. & Wakefield, M.
National Health & Medical Research Council (NHMRC)
1/01/16 → 30/06/19
Project: Research
The role of Bid in apoptosis within the ovary
Hutt, K. & Anderson, R.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/17
Project: Research
A novel strategy for fertility preservation in breast cancer patients
National Breast Cancer Foundation
1/01/14 → 31/12/15
Project: Research
Quality control in the female germ line
National Health & Medical Research Council (NHMRC)
1/01/13 → 31/12/16
Project: Research
Research Output 2006 2019
Oocytes from stem cells
Sarma, U. C., Findlay, J. K. & Hutt, K. J., 1 Feb 2019, In : Best Practice & Research: Clinical Obstetrics & Gynaecology. 55, p. 14-22 9 p.Research output: Contribution to journal › Article › Other › peer-review
Vincristine Chemotherapy Induces Atresia of Growing Ovarian Follicles in Mice
Winship, A. L., Carpenter, M., Griffiths, M. & Hutt, K. J., 1 May 2019, In : Toxicological sciences : an official journal of the Society of Toxicology. 169, 1, p. 43-53 11 p.Research output: Contribution to journal › Article › Research › peer-review
Dacarbazine depletes the ovarian reserve in mice and depletion is enhanced with age
Winship, A. L., Bakai, M., Sarma, U., Liew, S. H. & Hutt, K. J., 25 Apr 2018, In : Scientific Reports. 8, 1, 13 p., 6516.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Examination of the ovotoxicity of 5-fluorouracil in mice
Lambouras, M., Liew, S. H., Horvay, K., Abud, H. E., Stringer, J. M. & Hutt, K. J., Jun 2018, In : Journal of Assisted Reproduction and Genetics. 35, 6, p. 1053-1060 8 p.Research output: Contribution to journal › Article › Research › peer-review
Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility
Nguyen, Q. N., Zerafa, N., Liew, S. H., Morgan, F. H., Strasser, A., Scott, C. L., Findlay, J. K., Hickey, M. & Hutt, K. J., 1 Jun 2018, In : Cell Death and Disease. 9, 6, 12 p., 633.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File