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Personal profile

Research interests

To understand how the vascular complications of diabetes develop and progress and how we can target specific pathways to delay, stop or reverse diabetic micro-and macrovascular complications including heart and kidney disease.

Keywords

  • Diabetes
  • Diabetic complications
  • diabetic nephropathy
  • cardiovascular disease
  • oxidative stress
  • reactive oxygen species
  • unstable plaque
  • novel targets
  • clinical translation

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Projects 2014 2022

Research Output 1991 2019

Diabetes and Hypertension Differentially Affect Renal Catecholamines and Renal Reactive Oxygen Species

Watson, A., Gould, E., Penfold, S., Lambert, G. W., Pratama, P., Dai, A., Gray, S. P., Head, G. & Jandeleit-Dahm, K., Apr 2019, In : Frontiers in Physiology. 10, 309, 16 p., 309.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis

Pickering, R. J., Tikellis, C., Rosado, C. J., Tsorotes, D., Dimitropoulos, A., Smith, M., Huet, O., Seeber, R. M., Abhayawardana, R., Johnstone, E. K. M., Golledge, J., Wang, Y., Jandeleit-Dahm, K. A., Cooper, M. E., Pfleger, K. D. G. & Thomas, M. C., 2 Jan 2019, In : Journal of Clinical Investigation. 129, 1, p. 406-421 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes

Jha, J. C., Ho, F., Dan, C. & Jandeleit-Dahm, K., 1 Aug 2018, In : Clinical Science. 132, 16, p. 1811-1836 26 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

Mathew, G., Sharma, A., Pickering, R. J., Rosado, C. J., Lemarie, J., Mudgal, J., Thambi, M., Sebastian, S., Jandeleit-Dahm, K. A., de Haan, J. B. & Unnikrishnan, M. K., 3 Oct 2018, In : Free Radical Research. 52, 10, p. 1140-1157 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Cardiovascular Disease and Diabetic Kidney Disease

Maqbool, M., Cooper, M. E. & Jandeleit-Dahm, K. A. M., 1 May 2018, In : Seminars in Nephrology. 38, 3, p. 217-232 16 p.

Research output: Contribution to journalReview ArticleResearchpeer-review