Projects per year
Personal profile
Biography
NHMRC Overseas Biomedical Research Fellow 2011-2015
NARSAD-Maltz Young Investigator 2010
Related Links:
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- allosteric
- G protein-coupled receptor
- molecular modeling
- drug discovery
- bitopic
- metabotropic glutamate receptor
- muscarinic receptor
- signaling bias
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Kwan, P. (Primary Chief Investigator (PCI)), May, L. (Chief Investigator (CI)), Rollo, B. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Howden, S. (Chief Investigator (CI)), Christopoulos, A. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)), Scammells, P. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), Elliott, D. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Langmead, C. (Chief Investigator (CI)), Antonic-Baker, A. (Chief Investigator (CI)), Sumer, H. (Chief Investigator (CI)), Javaid, S. (Associate Investigator (AI)) & Gu, J. (Chief Investigator (CI))
1/06/22 → 31/05/27
Project: Research
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Positive allosteric modulation of anti-convulsant G protein-coupled receptor signalling to treat drug-resistant epilepsy
May, L. (Primary Chief Investigator (PCI)), Webb, G. (Chief Investigator (CI)), Carlsson, J. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Christopoulos, A. (Associate Investigator (AI)), Miao, Y. (Associate Investigator (AI)), O'Brien, T. (Associate Investigator (AI)), Rollo, B. (Associate Investigator (AI)), Casillas-Espinosa, P. (Associate Investigator (AI)), Gregory, K. (Associate Investigator (AI)), Scammells, P. (Associate Investigator (AI)) & Nguyen, T. (Associate Investigator (AI))
1/01/22 → 31/12/26
Project: Research
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Investigation of sex-dependent signalling of novel cognition-enhancers
Langiu, M. (Primary Chief Investigator (PCI)) & Gregory, K. (Supervisor)
Project: Research
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A computer based approach to drug discovery: Identifying New Treatments for Osteoporosis and Asthma
Keller, A. (Primary Chief Investigator (PCI)), Leach, K. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)) & Capuano, B. (Chief Investigator (CI))
Project: Research
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New Biomolecular Capabilities for the Melbourne Magnetic Resonance Facility
Gooley, P. R. (Primary Chief Investigator (PCI)), Scanlon, M. (Chief Investigator (CI)), Mackay, J. P. (Chief Investigator (CI)), Jones, O. A. H. (Chief Investigator (CI)), Komander, D. (Partner Investigator (PI)), McDevitt, C. A. (Chief Investigator (CI)), Urban, S. (Chief Investigator (CI)), Maher, M. J. (Chief Investigator (CI)), Griffin, M. D. W. (Chief Investigator (CI)), Call, M. E. (Partner Investigator (PI)), Borg, N. (Chief Investigator (CI)), Leach, K. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)) & Babon, J. (Partner Investigator (PI))
7/05/21 → 6/05/22
Project: Research
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A novel chemoreactive calcilytic for the potential treatment of autosomal dominant hypocalcemia
Dangerfield, J., DeBono, A., Keller, A. N., Josephs, T. M., Shackleford, D. M., Gregory, K. J., Leach, K. & Capuano, B., Oct 2025, In: Acta Pharmaceutica Sinica B. 15, 10, p. 5387-5399 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Next-Generation Analogues of AC265347 as Positive Allosteric Modulators of the Calcium-Sensing Receptor: Pharmacological Investigation of Structural Modifications at the Stereogenic Centre
Dinh, L. V., Dangerfield, J., DeBono, A., Keller, A. N., Josephs, T. M., Gregory, K. J., Leach, K. & Capuano, B., 13 Mar 2025, In: International Journal of Molecular Sciences. 26, 6, 17 p., 2580.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Structure-based discovery of positive allosteric modulators of the A1 adenosine receptor
Nguyen, A. T. N., Panel, N., Vo, D. D., Thai, B. S., Chia, L. Y., Lu, C. S., Hellyer, S. D., Langiu, M., Jörg, M., Gregory, K. J., Kihlberg, J., White, P. J., Scammells, P. J., Christopoulos, A., Carlsson, J. & May, L. T., 15 Jul 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 28, 10 p., e2421687122.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Development of Putative Bivalent Dicovalent Ligands for the Adenosine A1 Receptor
Payne, C. M., Baltos, J. A., Langiu, M., Sinh Lu, C., Tyndall, J. D. A., Gregory, K. J., May, L. T. & Vernall, A. J., 1 Oct 2024, In: ChemBioChem. 25, 19, 10 p., e202400242.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Pharmacology, Signaling and Therapeutic Potential of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators
Kos, J. A., Langiu, M., Hellyer, S. D. & Gregory, K. J., 13 Dec 2024, In: ACS Pharmacology & Translational Science. 7, 12, p. 3671-3690 20 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile2 Citations (Scopus)
Prizes
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Dean's Honours List in B.Sc. (Honours)
Gregory, K. (Recipient), 2014
Prize: Prize (including medals and awards)
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Graduate Student Best Abstract Award - Molecular Pharmacology division
Gregory, K. (Recipient), 2008
Prize: National/international honour
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Activities
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FASTtrack: Selling yourself as and early-mid career researcher
van der Westhuizen, E. (Organiser), Cao, E. (Organiser), Owens, N. (Organiser), Gregory, K. (Invited speaker), Carbone, S. (Invited speaker) & Voelcker, N. (Invited speaker)
2021 → …Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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MPGPCR organising committee 7-11 December 2014
Gregory, K. (Member)
1 Jan 2014 → 31 Dec 2014Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries