Projects per year
Personal profile
Biography
NHMRC Overseas Biomedical Research Fellow 2011-2015
NARSAD-Maltz Young Investigator 2010
Related Links:
Research area keywords
- allosteric
- G protein-coupled receptor
- molecular modeling
- drug discovery
- bitopic
- metabotropic glutamate receptor
- muscarinic receptor
- signaling bias
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Projects
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Finely tuned glutamate receptor inhibitors as novel therapeutics for neurodegenerative disorders
Gregory, K., Bradley, S. J. & Rook, J. M.
1/01/21 → 31/12/24
Project: Research
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Towards the rational design of calcium sensing receptor allosteric modulators for the treatment of osteoporosis and calcium handling disorders
Leach, K., Gregory, K., Conigrave, A., Capuano, B., Kufareva, I., Thakker, R. & Hannan, F. M.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/18 → 31/12/21
Project: Research
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Exploring metabotropic glutamate receptor 5 bias, allostery and heteromers
1/07/17 → 30/06/21
Project: Research
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A computer based approach to drug discovery: Identifying New Treatments for Osteoporosis and Asthma
Keller, A., Leach, K., Gregory, K. & Capuano, B.
Project: Research
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NHMRC Equipment Grant - FLIPR Tetra high-throughput cellular screening system
Sexton, P., Christopoulos, A., Leach, K., Gregory, K., Veldhuis, N., Poole, D. & Langmead, C.
1/01/18 → 31/12/18
Project: Research
Research output
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Correction to “Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple orthosteric Binding Sites” (Mol Pharmacol, (2020) 97, 1, (35-45) DOI: 10.1124/mol.119.118091)
Gregory, K. J., Giraldo, J., Diao, J., Christopoulos, A. & Leach, K., 1 Jan 2020, In : Molecular Pharmacology. 97, 1, p. 48-48 1 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
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Detailed In Vitro Pharmacological Characterization of Clinically Tested Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
Arsova, A., Møller, T. C., Vedel, L., Hansen, J. L., Foster, S. R., Gregory, K. J. & Bräuner-Osborne, H., 1 Jul 2020, In : Molecular Pharmacology. 98, 1, p. 49-60 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes
Hellyer, S. D., Aggarwal, S., Chen, A. N. Y., Leach, K., Lapinsky, D. J. & Gregory, K. J., 3 Jun 2020, In : ACS Chemical Neuroscience. 11, 11, p. 1597-1609 13 p.Research output: Contribution to journal › Article › Research › peer-review
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Differential contribution of metabotropic glutamate receptor 5 common allosteric binding site residues to biased allosteric agonism
Sengmany, K., Hellyer, S. D., Christopoulos, A., Lapinsky, D. J., Leach, K. & Gregory, K. J., 5 May 2020, (Accepted/In press) In : Biochemical Pharmacology. 15 p., 114011.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Emerging Leaders in Pharmacology and Translational Science Special Issue Editorial
Ritchie, R. H. & Gregory, K. J., 14 Feb 2020, In : ACS Pharmacology and Translational Science. 3, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › Other
Open Access
Prizes
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Dean's Honours List in B.Sc. (Honours)
Gregory, Karen (Recipient), 2014
Prize: Prize (including medals and awards)
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Graduate Student Best Abstract Award - Molecular Pharmacology division
Gregory, Karen (Recipient), 2008
Prize: National/international honour
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Activities
- 1 Submissions to industry or govt committees, commissions and inquiries
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7-11 December 2014
Karen Gregory (Member)
1 Jan 2014 → 31 Dec 2014Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries