Karen Gregory

Dr

20052021
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Personal profile

Biography

NHMRC Overseas Biomedical Research Fellow 2011-2015

NARSAD-Maltz Young Investigator 2010

Related Links:

Research area keywords

  • allosteric
  • G protein-coupled receptor
  • molecular modeling
  • drug discovery
  • bitopic
  • metabotropic glutamate receptor
  • muscarinic receptor
  • signaling bias

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2021

Research Output 2005 2019

Identification of monellin as the first naturally derived proteinaceous allosteric agonist of metabotropic glutamate receptor 5

Chen, A. N. Y., Hellyer, S. D., Trinh, P. N. H., Leach, K. & Gregory, K. J., 14 Apr 2019, (Accepted/In press) In : Basic and Clinical Pharmacology and Toxicology. 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology

Sengmany, K., Hellyer, S. D., Albold, S., Wang, T., Conn, P. J., May, L. T., Christopoulos, A., Leach, K. & Gregory, K. J., 1 May 2019, In : Neuropharmacology. 149, p. 83-96 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Biased agonism and allosteric modulation of metabotropic glutamate receptor 5

Trinh, P. N. H., May, L. T., Leach, K. & Gregory, K. J., 15 Nov 2018, In : Clinical science (London, England : 1979). 132, 21, p. 2323-2338 16 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Dual Action Calcium-Sensing Receptor Modulator Unmasks Novel Mode-Switching Mechanism

Gregory, K., Kufareva, I., Keller, A. N., Khajehali, E., Mun, H., Goolam, M. A., Mason, R. S., Capuano, B., Conigrave, A., Christopoulos, A. & Leach, K., 12 Sep 2018, In : ACS Pharmacology and Translational Sciences. 1, 2, p. 96-109 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Identification of global and ligand-specific calcium sensing receptor activation mechanisms S

Keller, A., Kufareva, I., Josephs, T. M., Diao, J., Mai, V. T-V., Conigrave, A. D., Christopoulos, A., Gregory, K. J. & Leach, K., 1 Jun 2018, In : Molecular Pharmacology. 93, 6, p. 619-630 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Prizes

Dean's Honours List in B.Sc. (Honours)

Karen Gregory (Recipient), 2014

Prize: Prize (including medals and awards)

Dux - Honours Class, 2004

Karen Gregory (Recipient), 2014

Prize: Prize (including medals and awards)

Graduate Student Travel Award

Karen Gregory (Recipient), 2007

Prize: National/international honour

Runner-Up

Karen Gregory (Recipient), 2007

Prize: National/international honour

Activities 2014 2014

  • 1 Submissions to industry or govt committees, commissions and inquiries

7-11 December 2014

Karen Gregory (Member)
1 Jan 201431 Dec 2014

Activity: External Academic EngagementSubmissions to industry or govt committees, commissions and inquiries