Projects per year
Personal profile
Biography
NHMRC Overseas Biomedical Research Fellow 2011-2015
NARSAD-Maltz Young Investigator 2010
Related Links:
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- allosteric
- G protein-coupled receptor
- molecular modeling
- drug discovery
- bitopic
- metabotropic glutamate receptor
- muscarinic receptor
- signaling bias
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Kwan, P. (Primary Chief Investigator (PCI)), May, L. (Chief Investigator (CI)), Rollo, B. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Howden, S. (Chief Investigator (CI)), Christopoulos, A. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)), Scammells, P. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), Elliot, D. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Langmead, C. (Chief Investigator (CI)), Antonic-Baker, A. (Chief Investigator (CI)), Sumer, H. (Chief Investigator (CI)), Javaid, S. (Associate Investigator (AI)) & Gu, J. (Chief Investigator (CI))
1/06/22 → 31/05/27
Project: Research
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Positive allosteric modulation of anti-convulsant G protein-coupled receptor signalling to treat drug-resistant epilepsy
May, L. (Primary Chief Investigator (PCI)), Webb, G. (Chief Investigator (CI)), Carlsson, J. (Chief Investigator (CI)), Baltos, J.-A. (Chief Investigator (CI)), TN Nguyen, A. (Chief Investigator (CI)), Christopoulos, A. (Associate Investigator (AI)), Miao, Y. (Associate Investigator (AI)), O'Brien, T. (Associate Investigator (AI)), Rollo, B. (Associate Investigator (AI)), Casillas-Espinosa, P. (Associate Investigator (AI)), Gregory, K. (Associate Investigator (AI)), Scammells, P. (Associate Investigator (AI)) & Nguyen, T. (Associate Investigator (AI))
1/01/22 → 31/12/25
Project: Research
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A computer based approach to drug discovery: Identifying New Treatments for Osteoporosis and Asthma
Keller, A. (Primary Chief Investigator (PCI)), Leach, K. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)) & Capuano, B. (Chief Investigator (CI))
Project: Research
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New Biomolecular Capabilities for the Melbourne Magnetic Resonance Facility
Gooley, P. R. (Primary Chief Investigator (PCI)), Scanlon, M. (Chief Investigator (CI)), Mackay, J. P. (Chief Investigator (CI)), Jones, O. A. H. (Chief Investigator (CI)), Komander, D. (Partner Investigator (PI)), McDevitt, C. A. (Chief Investigator (CI)), Urban, S. (Chief Investigator (CI)), Maher, M. J. (Chief Investigator (CI)), Griffin, M. (Chief Investigator (CI)), Call, M. E. (Partner Investigator (PI)), Borg, N. (Chief Investigator (CI)), Leach, K. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)) & Babon, J. (Partner Investigator (PI))
7/05/21 → 6/05/22
Project: Research
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Development of Putative Bivalent Dicovalent Ligands for the Adenosine A1 Receptor
Payne, C. M., Baltos, J. A., Langiu, M., Sinh Lu, C., Tyndall, J. D. A., Gregory, K. J., May, L. T. & Vernall, A. J., 1 Oct 2024, In: ChemBioChem. 25, 19, 10 p., e202400242.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Pharmacology, Signaling and Therapeutic Potential of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators
Kos, J. A., Langiu, M., Hellyer, S. D. & Gregory, K. J., 13 Dec 2024, In: ACS Pharmacology & Translational Science. 7, 12, p. 3671-3690 20 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile -
SCA44- and SCAR13-associated GRM1 mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms
Wang, Y., Muraleetharan, A., Langiu, M., Gregory, K. J. & Hellyer, S. D., Nov 2024, In: British Journal of Pharmacology. 181, 22, p. 4514-4530 17 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
The role of the adenosine system in epilepsy and its comorbidities
Baltos, J. A., Casillas-Espinosa, P. M., Rollo, B., Gregory, K. J., White, P. J., Christopoulos, A., Kwan, P., O'Brien, T. J. & May, L. T., Jul 2024, In: British Journal of Pharmacology. 181, 14, p. 2143-2157 15 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access16 Citations (Scopus) -
Trace amine associated receptor 1: predicted effects of single nucleotide variants on structure-function in geographically diverse populations
Shajan, B., Marri, S., Bastiampillai, T., Gregory, K. J., Hellyer, S. D. & Nair, P. C., 11 Jun 2024, In: Human Genomics. 18, 1, 13 p., 61.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)
Prizes
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Dean's Honours List in B.Sc. (Honours)
Gregory, K. (Recipient), 2014
Prize: Prize (including medals and awards)
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Graduate Student Best Abstract Award - Molecular Pharmacology division
Gregory, Karen (Recipient), 2008
Prize: National/international honour
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Activities
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FASTtrack: Selling yourself as and early-mid career researcher
van der Westhuizen, E. (Organiser), Cao, E. (Organiser), Owens, N. (Organiser), Gregory, K. (Invited speaker), Carbone, S. (Invited speaker) & Voelcker, N. (Invited speaker)
2021 → …Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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MPGPCR organising committee 7-11 December 2014
Karen Gregory (Member)
1 Jan 2014 → 31 Dec 2014Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries