Projects per year
Personal profile
Biography
A central objective of my research is to develop imaging techniques to better understand the underlying mechanisms of different disease progression and the impact of therapy. My research is based on the combination of novel enzymatic and chemical modification techniques for recombinant antibodies. Using the bacterial transpeptidase sortase and click chemistry for imaging and drug delivery, I am progressing novel theranostic agents towards clinical use for the benefit of patients.
Research area keywords
- PET/CT imaging
- Bioconjugation
- Antibody
- Theranostic
- Metal-Organic Framework
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 4 Finished
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Clinical imaging of CXCR4 in the development of an i-body therapy for idiopathic pulmonary fibrosis
Foley, M., Hagemeyer, C., Egan, G., Scott, A., Westall, G., Donnelly, P. S. & Alt, K.
1/02/20 → 31/12/21
Project: Research
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Novel targeted Onco-theranostic nanoparticles for personalised therapy and real-time monitoring
1/01/18 → 31/12/21
Project: Research
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Novel targeted PEG nanoparticles for cancer treatment and monitoring
Alt, K. & Paterson, B.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/16 → 31/12/19
Project: Research
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A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls
McMahon, J. H., Zerbato, J. M., Lau, J. S. Y., Lange, J. L., Roche, M., Tumpach, C., Dantanarayana, A., Rhodes, A., Chang, J., Rasmussen, T. A., Mackenzie, C. A., Alt, K., Hagenauer, M., Roney, J., O‘Bryan, J., Carey, A., McIntyre, R., Beech, P., O'Keefe, G. J., Wichmann, C. W. & 11 others, , Mar 2021, In: EBioMedicine. 65, 10 p., 103252.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Collagen-targeted peptides for molecular imaging of diffuse cardiac fibrosis
Ezeani, M., Noor, A., Alt, K., Lal, S., Donnelly, P. S., Hagemeyer, C. E. & Niego, BE., 21 Sep 2021, In: Journal of the American Heart Association. 10, 18, 28 p., e022139.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s
Finnegan, J. R., Pilkington, E. H., Alt, K., Rahim, M. A., Kent, S. J., Davis, T. P. & Kempe, K., 7 Jun 2021, In: Chemical Science. 12, 21, p. 7350-7360 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Collagen-Targeted Theranostic Nanosponges for Delivery of the Matrix Metalloproteinase 14 Inhibitor Naphthofluorescein
Wang, T-Y., Kendrick-Williams, L. L., Choy, M. Y., Gilmore, K. A., Bonnard, T., Pearce, H. A., Law, L. S., Carmichael, I., Cody, S., Alt, K., Hagemeyer, C. & Harth, E., 12 May 2020, In: Chemistry of Materials. 32, 9, p. 3707-3714 8 p.Research output: Contribution to journal › Article › Research › peer-review
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Carbohydrates@MOFs
Astria, E., Thonhofer, M., Ricco, R., Liang, W., Chemelli, A., Tarzia, A., Alt, K., Hagemeyer, C. E., Rattenberger, J., Schroettner, H., Wrodnigg, T., Amenitsch, H., Huang, D. M., Doonan, C. J. & Falcaro, P., 1 Jun 2019, In: Materials Horizons. 6, 5, p. 969-977 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile23 Citations (Scopus)
Prizes
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AMREP Collaborative Seed Grant
Alt, Karen (Recipient), 2016
Prize: Prize (including medals and awards)
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Central Clinical School Travel Grant
Alt, Karen (Recipient), 2016
Prize: Prize (including medals and awards)
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Central Clinical School Travel Grant
Alt, Karen (Recipient), 2015
Prize: Prize (including medals and awards)
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DFG (German Research Foundation) Fellowship
Alt, Karen (Recipient), 2012
Prize: Prize (including medals and awards)
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ECS Harold Mitchell Travelling Fellowship
Alt, Karen (Recipient), 2014
Prize: Prize (including medals and awards)