Projects per year
Personal profile
Biography
A central objective of my research is to develop imaging techniques to better understand the underlying mechanisms of different disease progression and the impact of therapy. My research is based on the combination of novel enzymatic and chemical modification techniques for recombinant antibodies. Using the bacterial transpeptidase sortase and click chemistry for imaging and drug delivery, I am progressing novel theranostic agents towards clinical use for the benefit of patients. I have established and currently head a NanoPET/CT preclinical imaging facility at AMREP.
Keywords
- PET/CT imaging
- Bioconjugation
- Antibody
- Theranostic
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2016 2019
Novel targeted PEG nanoparticles for cancer treatment and monitoring
National Health & Medical Research Council (NHMRC)
1/01/16 → 31/12/19
Project: Research
Research Output 2008 2018
Magnetic fibrinolysis: putting the therapeutic wheels in a corkscrew motion
Medcalf, R. L., Hagemeyer, C. E. & Alt, K. 1 Apr 2018 In : Journal of Thrombosis and Haemostasis. 16, 4, p. 615-617 3 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice
Heywood, S. E., Richart, A. L., Henstridge, D. C., Alt, K., Kiriazis, H., Zammit, C., Carey, A. L., Kammoun, H. L., Delbridge, L. M., Reddy, M., Chen, Y. C., Du, X. J., Hagemeyer, C. E., Febbraio, M. A., Siebel, A. L. & Kingwell, B. A. 11 Oct 2017 In : Science Translational Medicine. 9, 411, 10 p., eaam6084Research output: Contribution to journal › Article › Research › peer-review
Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast
Ta, H. T., Li, Z., Hagemeyer, C. E., Cowin, G., Zhang, S., Palasubramaniam, J., Alt, K., Wang, X., Peter, K. & Whittaker, A. K. 1 Jul 2017 In : Biomaterials. 134, p. 31-42 12 p.Research output: Contribution to journal › Article › Research › peer-review
Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single-Chain Antibody Specific for Activated GPIIb/IIIa
Bonnard, T., Tennant, Z., Niego, B., Kanojia, R., Alt, K., Jagdale, S., Law, L. S., Rigby, S., Medcalf, R. L., Peter, K. & Hagemeyer, C. E. 3 Feb 2017 In : American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 6, 2, e004535Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Self-Assembled Nanoparticles from Phenolic Derivatives for Cancer Therapy
Dai, Y., Guo, J., Wang, T. Y., Ju, Y., Mitchell, A. J., Bonnard, T., Cui, J., Richardson, J. J., Hagemeyer, C. E., Alt, K. & Caruso, F. 23 Aug 2017 In : Advanced Healthcare Materials. 6, 16, 7 p., 1700467Research output: Contribution to journal › Article › Research › peer-review