Projects per year
Personal profile
Biography
A central objective of my research is to develop imaging techniques to better understand the underlying mechanisms of different disease progression and the impact of therapy. My research is based on the combination of novel enzymatic and chemical modification techniques for recombinant antibodies. Using the bacterial transpeptidase sortase and click chemistry for imaging and drug delivery, I am progressing novel theranostic agents towards clinical use for the benefit of patients.
Keywords
- PET/CT imaging
- Bioconjugation
- Antibody
- Theranostic
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2016 2019
Research Output 2008 2019
Carbohydrates@MOFs
Astria, E., Thonhofer, M., Ricco, R., Liang, W., Chemelli, A., Tarzia, A., Alt, K., Hagemeyer, C. E., Rattenberger, J., Schroettner, H., Wrodnigg, T., Amenitsch, H., Huang, D. M., Doonan, C. J. & Falcaro, P., 1 Jun 2019, In : Materials Horizons. 6, 5, p. 969-977 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles
Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., May 2019, In : Macromolecular Rapid Communications. 40, 10, 6 p., 1800911.Research output: Contribution to journal › Article › Research › peer-review
Magnetic fibrinolysis: putting the therapeutic wheels in a corkscrew motion
Medcalf, R. L., Hagemeyer, C. E. & Alt, K., 1 Apr 2018, In : Journal of Thrombosis and Haemostasis. 16, 4, p. 615-617 3 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
The Canonical Wnt/β-catenin Pathway as a Therapeutic Target in Multiple Myeloma
Savvidou, I., Khong, T., Spencer, A. & Alt, K. M., Jul 2018, In : Archives of Medical Research. 6, 7, p. 1-15 15 p.Research output: Contribution to journal › Review Article › Research › peer-review
High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice
Heywood, S. E., Richart, A. L., Henstridge, D. C., Alt, K., Kiriazis, H., Zammit, C., Carey, A. L., Kammoun, H. L., Delbridge, L. M., Reddy, M., Chen, Y. C., Du, X. J., Hagemeyer, C. E., Febbraio, M. A., Siebel, A. L. & Kingwell, B. A., 11 Oct 2017, In : Science Translational Medicine. 9, 411, 10 p., eaam6084.Research output: Contribution to journal › Article › Research › peer-review
Prizes
AMREP Collaborative Seed Grant
Karen Alt (Recipient), 2016
Prize: Prize (including medals and awards)
Central Clinical School Travel Grant
Karen Alt (Recipient), 2015
Prize: Prize (including medals and awards)
Central Clinical School Travel Grant
Karen Alt (Recipient), 2016
Prize: Prize (including medals and awards)
DFG (German Research Foundation) Fellowship
Karen Alt (Recipient), 2012
Prize: Prize (including medals and awards)
ECS Harold Mitchell Travelling Fellowship
Karen Alt (Recipient), 2014
Prize: Prize (including medals and awards)