Projects per year
Personal profile
Biography
A central objective of my research is to develop imaging techniques to better understand the underlying mechanisms of different disease progression and the impact of therapy. My research is based on the combination of novel enzymatic and chemical modification techniques for recombinant antibodies. Using the bacterial transpeptidase sortase and click chemistry for imaging and drug delivery, I am progressing novel theranostic agents towards clinical use for the benefit of patients.
Research area keywords
- PET/CT imaging
- Bioconjugation
- Antibody
- Theranostic
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Novel targeted PEG nanoparticles for cancer treatment and monitoring
National Health & Medical Research Council (NHMRC)
1/01/16 → 31/12/19
Project: Research
Research Output
Carbohydrates@MOFs
Astria, E., Thonhofer, M., Ricco, R., Liang, W., Chemelli, A., Tarzia, A., Alt, K., Hagemeyer, C. E., Rattenberger, J., Schroettner, H., Wrodnigg, T., Amenitsch, H., Huang, D. M., Doonan, C. J. & Falcaro, P., 1 Jun 2019, In : Materials Horizons. 6, 5, p. 969-977 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
4
Citations
(Scopus)
Development of a novel peptide tracer for detection of cardiac fibrosis and atrial fibrillation using mouse models of cardiomyopathies
Niego, B., Alt, K., Noor, A., How, O. J., Du, X-J., Donnelly, P. S., McMullen, J. & Hagemeyer, C., 9 Jul 2019.Research output: Contribution to conference › Abstract
Engineering Antibodies with C-Terminal Sortase-Mediated Modification for Targeted Nanomedicine
Hashad, R. A., Lange, J. L., Tan, N. C. W., Alt, K. & Hagemeyer, C. E., 2019, Bioconjugation : Methods in Molecular Biology. Massa, S. & Devoogdt, N. (eds.). New York, NY: Humana Press, p. 67-80 14 p. (Methods in Molecular Biology; vol. 2033).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles
Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., May 2019, In : Macromolecular Rapid Communications. 40, 10, 6 p., 1800911.Research output: Contribution to journal › Article › Research › peer-review
3
Citations
(Scopus)
Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake
Cui, J., Alt, K., Ju, Y., Gunawan, S. T., Braunger, J. A., Wang, T. Y., Dai, Y., Dai, Q., Richardson, J. J., Guo, J., Björnmalm, M., Hagemeyer, C. E. & Caruso, F., 9 Sep 2019, In : Biomacromolecules. 20, 9, p. 3592-3600 9 p.Research output: Contribution to journal › Article › Research › peer-review
1
Citation
(Scopus)
Prizes
AMREP Collaborative Seed Grant
Karen Alt (Recipient), 2016
Prize: Prize (including medals and awards)
Central Clinical School Travel Grant
Karen Alt (Recipient), 2015
Prize: Prize (including medals and awards)
Central Clinical School Travel Grant
Karen Alt (Recipient), 2016
Prize: Prize (including medals and awards)
DFG (German Research Foundation) Fellowship
Karen Alt (Recipient), 2012
Prize: Prize (including medals and awards)
ECS Harold Mitchell Travelling Fellowship
Karen Alt (Recipient), 2014
Prize: Prize (including medals and awards)