Projects per year
Personal profile
Biography
Dr. Kallyanashis Paul's notable impact in biomaterials development, tissue engineering, and regenerative medicine for both soft and hard tissue regeneration has garnered significant attention within the scientific community. His pioneering research shifted the field from passive scaffold approaches to active immunomodulation strategies, significantly elevating scientific attention to understudied areas in women's health, such as pelvic organ prolapse and diagnostic medical devices for conditions like endometriosis.
Key impacts of his research include:
- Developing degradable multicomponent-tissue engineering constructs with optimal biomechanical strength.
- Outlining micro/nano topographic biophysical guidelines for immunomodulation and tissue integration.
- Synthesising biocompatible hydrogels for cell-based printing.
- Developing multicellular 3D culture systems for 3D Printed In Vitro models.
- Defining technology readiness levels (TRL) and commercialization strategies.
Research area keywords
- 3D Printing
- 3D cell culture models
- AI-guided Image Analysis
- immunomodulation
- Biomaterials Engineering
Collaborations and top research areas from the last five years
Projects
- 1 Active
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3D Bioprinted Strategies for Improving Female Pelvic Reconstructive Surgery Outcomes
Paul, K. (Primary Chief Investigator (PCI)), Mukherjee, S. (Chief Investigator (CI)), Darzi, S. (Chief Investigator (CI)), Fitzgerald, H. (Chief Investigator (CI)), Fernando, S. (Chief Investigator (CI)), Rosamilia, A. (Associate Investigator (AI)), Gargett, C. (Associate Investigator (AI)) & Werkmeister, J. A. (Associate Investigator (AI))
1/03/24 → 28/02/26
Project: Research
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3D Printed Mesh Geometry Modulates Immune Response and Interface Biology in Mouse and Sheep Model: Implications for Pelvic Floor Surgery
Paul, K., Darzi, S., O'Connell, C. D., Hennes, D. M. Z. B., Rosamilia, A., Gargett, C. E., Werkmeister, J. A. & Mukherjee, S., 20 Mar 2025, In: Advanced Science. 12, 11, 21 p., 2405004.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Immunobiology of foreign body response to composite PLACL/gelatin electrospun nanofiber meshes with mesenchymal stem/stromal cells in a mouse model: Implications in pelvic floor tissue engineering and regeneration
Darzi, S., Alappadan, J., Paul, K., Mazdumder, P., Rosamilia, A., Truong, Y. B., Gargett, C., Werkmeister, J. & Mukherjee, S., Dec 2023, In: Biomaterials Advances. 155, 17 p., 213669.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Identification and characterisation of maternal perivascular SUSD2+ placental mesenchymal stem/stromal cells
Khanmohammadi, M., Mukherjee, S., Darzi, S., Paul, K., Werkmeister, J. A., Cousins, F. L. & Gargett, C. E., Sept 2021, In: Cell and Tissue Research. 385, 3, p. 803–815 13 p.Research output: Contribution to journal › Article › Research › peer-review
10 Citations (Scopus) -
Immunobiology and application of aloe vera‐based scaffolds in tissue engineering
Darzi, S., Paul, K., Leitan, S., Werkmeister, J. A. & Mukherjee, S., 2 Feb 2021, In: International Journal of Molecular Sciences. 22, 4, 19 p., 1708.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access40 Citations (Scopus) -
Vaginal delivery of tissue engineered endometrial mesenchymal stem/stromal cells in an aloe vera-alginate hydrogel alleviates maternal simulated birth injury
Paul, K., Darzi, S., Del Borgo, M. P., Cousins, F. L., Werkmeister, J. A., Gargett, C. E. & Mukherjee, S., Mar 2021, In: Applied Materials Today. 22, 12 p., 100890.Research output: Contribution to journal › Article › Research › peer-review
21 Citations (Scopus)