Projects per year
Personal profile
Biography
Kade works in the Faculty of Pharmacy and Pharm Science at Monash University as a Research Fellow.
Research interests
Peptide synthesis
Peptide and protein modification chemistry
Development of peptide therapeutics
Antimicrobial peptides
Research area keywords
- Peptides
- Peptide Drugs
- Polymyxin
- Antibacterials
- Antibiotic resistance
- Synthetic Chemistry
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting the Urgent Need for New Antibiotics against Gram-negative ‘Superbugs’
Li, J., Velkov, T., Roberts, K., Thompson, P. & Nation, R.
1/08/17 → 31/07/23
Project: Research
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Targeting Superbugs: discovery and development of new broad-spectrum lipopeptide
Li, J., Dudley, M. N., Griffith, D., Hecker, S., Lomovskaya, O., Nation, R., Roberts, K., Thompson, P. & Velkov, T.
National Institutes of Health (United States)
1/06/12 → 31/05/17
Project: Research
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A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threateningAcinetobacter baumannii
Jiang, X., Patil, N. A., Azad, M. A. K., Wickremasinghe, H., Yu, H., Zhao, J., Zhang, X., Li, M., Gong, B., Wan, L., Ma, W., Thompson, P. E., Yang, K., Yuan, B., Schreiber, F., Wang, L., Velkov, T., Roberts, K. D. & Li, J., 28 Sep 2021, In: Chemical Science. 12, 36, p. 12211-12220 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Synchrotron-based x-ray fluorescence microscopy reveals accumulation of polymyxins in single human alveolar epithelial cells
Azad, M. A. K., Zhang, S., Li, J., Kim, Y., Yu, H. H., Fulcher, A. J., Howard, D. L., De Jonge, M. D., James, S. A., Roberts, K. D., Velkov, T., Fu, J., Zhou, Q. T. & Li, J., May 2021, In: Antimicrobial Agents and Chemotherapy. 65, 5, 9 p., e02314-20.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Molecular dynamics simulations informed by membrane lipidomics reveal the structure-interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii
Jiang, X., Yang, K., Yuan, B., Han, M., Zhu, Y., Roberts, K. D., Patil, N. A., Li, J., Gong, B., Hancock, R. E. W., Velkov, T., Schreiber, F., Wang, L. & Li, J., Dec 2020, In: Journal of Antimicrobial Chemotherapy. 75, 12, p. 3534-3543 10 p.Research output: Contribution to journal › Article › Research › peer-review
10 Citations (Scopus) -
Simulations of octapeptin-outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency
Jiang, X., Yang, K., Yuan, B., Gong, B., Wan, L., Patil, N. A., Swarbrick, J. D., Roberts, K. D., Schreiber, F., Wang, L., Velkov, T. & Li, J., 20 Nov 2020, In: Journal of Biological Chemistry. 295, 47, p. 15902-15912 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Structure-Interaction Relationship of Polymyxins with the Membrane of Human Kidney Proximal Tubular Cells
Jiang, X., Zhang, S., Azad, M. A. K., Roberts, K. D., Wan, L., Gong, B., Yang, K., Yuan, B., Uddin, H., Li, J., Thompson, P. E., Velkov, T., Fu, J., Wang, L. & Li, J., 14 Aug 2020, In: ACS Infectious Diseases. 6, 8, p. 2110-2119 10 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus)