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Research Output 2002 2019

2019
3 Citations (Scopus)

The transgenerational effects of oocyte mitochondrial supplementation

St. John, J. C., Makanji, Y., Johnson, J. L., Tsai, T. S., Lagondar, S., Rodda, F., Sun, X., Pangestu, M., Chen, P. & Temple-Smith, P., 1 Dec 2019, In : Scientific Reports. 9, 1, 12 p., 6694.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2018
5 Citations (Scopus)

The association of mitochondrial DNA haplotypes and phenotypic traits in pigs

St John, J. C. & Tsai, T. S., 6 Jul 2018, In : BMC Genetics. 19, 1, 12 p., 41.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

Sun, X., Vaghjiani, V., Jayasekara, W. S. N., Cain, J. E. & St John, J. C., 17 Dec 2018, In : Clinical Epigenetics. 10, 1, 17 p., 157.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)
1 Citation (Scopus)

The mitochondrial genome: How it drives fertility

St John, J. C., Srirattana, K., Tsai, T. S. & Sun, X., 1 Jan 2018, In : Reproduction, Fertility and Development. 30, 1, p. 118-139 22 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The molecular characterisation of mitochondrial DNA deficient oocytes using a pig model

Tsai, T. S., Tyagi, S. & St John, J. C., 1 May 2018, In : Human Reproduction. 33, 5, p. 942-953 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
9 Citations (Scopus)

Cattle phenotypes can disguise their maternal ancestry

Srirattana, K., McCosker, K., Schatz, T. & St. John, J. C., 26 Jun 2017, In : BMC Genetics. 18, 1, 59.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Manipulating the mitochondrial genome to enhance cattle embryo development

Srirattana, K. & St. John, J. C., 1 Jul 2017, In : G3: Genes, Genomes, Genetics. 7, 7, p. 2065-2080 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns

Lee, W. T., Sun, X., Tsai, T-S., Johnson, J. L., Gould, J. A., Garama, D. J., Gough, D. J., McKenzie, M., Trounce, I. A. & St John, J. C., 1 Jan 2017, In : Cell Death Discovery. 3, 11 p., 17062.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells

Vaghjiani, V., Cain, J. E., Lee, W., Vaithilingam, V., Tuch, B. E. & St John, J. C., 15 Oct 2017, In : Stem Cells and Development. 26, 20, p. 1505-1519 15 p.

Research output: Contribution to journalArticleResearchpeer-review

The molecular characterization of porcine egg precursor cells

Tsai, T-S., Johnson, J., White, Y. & St John, J. C., 2017, In : Oncotarget. 8, 38, p. 63484-63505 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016
1 Citation (Scopus)

Analysis of mitochondrial DNA copy number and its regulation through DNA methylation of POLGA

Sun, X., Lee, W., Vaghjiani, V. & St. John, J. C., 2016, Methods in Molecular Biology. McKenzie, M. (ed.). 3rd ed. Humana Press, Vol. 1351. p. 131-141 11 p. (Methods in Molecular Biology; vol. 1351).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)

Analysis of the mitochondrial DNA and its replicative capacity in induced pluripotent stem cells

Cagnone, G., Vaghjiani, V., Lee, W., Sun, C., Johnson, J., Yeung, K-Y. & St.John, J. C., 1 Jan 2016, Induced Pluripotent Stem (iPS) Cells: Methods and Protocols. Turksen, K. & Nagy, A. (eds.). New York NY USA: Humana Press, Vol. 1357. p. 231-267 37 p. (Methods in Molecular Biology; vol. 1357).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

5 Citations (Scopus)

Deletion of the Complex I subunit NDUFS4 adversely modulates cellular differentiation

Johnson, J., Lee, W., Frazier, A. E., Vaghjiani, V., Laskowski, A., Rodriguez, A. L., Cagnone, G. L., McKenzie, M., White, S. J., Nisbet, D. R., Thorburn, D. R. & St. John, J. C., 2016, In : Stem Cells and Development. 25, 3, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Mitochondrial DNA as an initiator of tumorigenesis

Lee, W. T. Y. & St. John, J. C., 31 Mar 2016, In : Cell Death and Disease. 7, p. e2171 2 p., e2171.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
File
23 Citations (Scopus)

Mitochondrial DNA copy number and replication in reprogramming and differentiation

St. John, J. C., 1 Apr 2016, In : Seminars in Cell and Developmental Biology. 52, p. 93-101 9 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

58 Citations (Scopus)

Mitochondrial DNA plasticity is an essential inducer of tumorigenesis

Lee, WTY., Cain, JE., Cuddihy, AR., Dickinson, A., Yeung, K-Y., Kumar, B., Johns, TG., Watkins, DN., Spencer, A., St John, JC. & Johnson, J., 2016, In : Cell Death Discovery. 2, p. 1 - 11 11 p., 16016.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Mitochondrial DNA supplementation as an enhancer of female reproductive capacity

St John, J. C., Tsai, T-S. & Cagnone, G. L. M., 2016, In : Current Opinion in Obstetrics and Gynecology. 28, 3, p. 211 - 216 6 p.

Research output: Contribution to journalArticleOtherpeer-review

35 Citations (Scopus)

Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

Cagnone, G., Tsai, T-S., Makanji, Y., Matthews, P. M., Gould, J. A., Bonkowski, M. S., Elgass, K., Wong, A. S. A., Wu, L. E., McKenzie, M., Sinclair, D. A. & St John, J. C., 2016, In : Scientific Reports. 6, p. 1 - 15 15 p., 23229.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)

Segregation of naturally occurring mitochondrial DNA variants in a mini-pig model

Cagnone, G., Tsai, T-S., Srirattana, K., Rossello, F., Powell, D. R., Rohrer, G., Cree, L., Trounce, I. A. & St John, J. C., Mar 2016, In : Genetics. 202, 3, p. 931 - 944 14 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

The relationship between mitochondrial DNA haplotype and the reproductive capacity of domestic pigs (Sus scrofa domesticus)

Tsai, T-S., Rajasekar, S. & St. John, J. C., 18 May 2016, In : BMC Genetics. 17, 1, 17 p., 67.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The role of mitochondria and mitochondrial DNA in fertilisation and development outcome

St John, J. C. & Tsai, T-S., 24 Oct 2016, IVF Worldwide: Virtual Academy of Egg Health. IVF Worldwide

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

9 Citations (Scopus)

The role of mitochondrial DNA copy number, variants, and haplotypes in farm animal developmental outcome

Tsai, T. & St. John, J. C., Jul 2016, In : Domestic Animal Endocrinology. 56, p. S133-S146 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

11 Citations (Scopus)

The role of the mtDNA set point in differentiation, development and tumorigenesis

Sun, X. & St. John, J. C., 27 Sep 2016, In : Biochemical Journal. 473, 19, p. 2955-2971 17 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

2015
1 Citation (Scopus)

Analysis of mitochondrial DNA in induced pluripotent and embryonic stem cells

Lee, W., Kelly, R. D. W., Yeung, K. Y. V., Cagnone, G., McKenzie, M. & St John, J. C., 2015, Cell Reprogramming : Methods and Protocols. Verma, P. J. & Sumer, H. (eds.). 1st ed. Totowa NJ USA: Humana Press, p. 219 - 252 34 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

6 Citations (Scopus)

Differences in mitochondrial DNA inheritance and function align with body conformation in genetically lean and fat sheep

Henry, B. A., Loughnan, R., Hickford, J., Young, I. R., St John, J. C. & Clarke, I., 1 May 2015, In : Journal of Animal Science. 93, 5, p. 2083-2093 11 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny

Lee, W., Johnson, J. L., Gough, D. J., Donoghue, J. F., Cagnone, G., Vaghjiani, V., Brown, K. A., Johns, T. G. & St John, J. C., 2015, In : Cell Death and Disease. 6, 2 (Art. No: e1664), p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
96 Citations (Scopus)

Mitochondrial dysfunction in oocytes of obese mothers: Transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors

Wu, L., Russell, D. L., Wong, S. L., Chen, M., Tsai, T-S., St John, J. C., Norman, R. J., Febbraio, M. A., Carroll, J. G. & Robker, R., 2015, In : Development. 142, 4, p. 681 - 691 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
23 Citations (Scopus)

The control of mitochondrial DNA replication during development and tumorigenesis

Lee, W. T. Y. & St John, J. C., 2015, In : Annals of the New York Academy of Sciences. 1350, 1, p. 95-106 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

The mitochondrion, its genome and their contribution to well-being and disease

St. John, J. C., 19 Jun 2015, In : Molecular Human Reproduction. 21, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

2014
7 Citations (Scopus)

Capture of somatic mtDNA point mutations with severe effects on oxidative phosphorylation in synaptosome cybrid clones from human brain

McKenzie, M., Chiotis, M., Hroudova, J., Lopez Sanchez, M. I. G., Lim, S. C., Cook, M. J., McKelvie, P. A., Cotton, R. G. H., Murphy, M. A., St John, J. C. & Trounce, I. A., 2014, In : Human Mutation. 35, 12, p. 1476 - 1484 9 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Damaging legacy: maternal cigarette smoking has long-term consequences for male offspring fertility

Sobinoff, A. P., Sutherland, J., Beckett, E. L., Stanger, S. J., Johnson, R., Jarnicki, A. G., McCluskey, A., St John, J. C., Hansbro, P. M. & McLaughlin, E. A., 2014, In : Human Reproduction. 29, 12, p. 2719 - 2735 17 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

High cortisol responses identify propensity for obesity that is linked to thermogenesis in skeletal muscle

Lee, T-K. K., Clarke, I. J., St John, J. C., Young, I. R., Leury, B., Rao, A., Andrews, Z. B. & Henry, B. A., 2014, In : FASEB Journal. 28, 1, p. 35 - 44 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Mitochondrial DNA - its transmission from gametes and enbryos

St John, J. C., 2014, Principles of Cloning. Cibelli, J., Gurdon, J., Wilmut, I., Jaenisch, R., Lanza, R., West, M. D. & Campbell, K. H. S. (eds.). 2nd ed. USA: Elsevier, p. 429 - 439 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Mitochondrial research in Australia: a major player in worldwide trends

Nagley, P., St John, J. C., Gabriel, K. & McKenzie, M., 2014, In : Biochimica et Biophysica Acta. General Subjects. 1840, 4, p. 1225 - 1226 2 p.

Research output: Contribution to journalLetterOther

Modifying the mitochondrial genome to enhance animal production

St John, J. C., Clarke, I. J. & Srirattana, K., 2014, p. 61 - 61. 1 p.

Research output: Contribution to conferenceAbstract

50 Citations (Scopus)

The control of mtDNA replication during differentiation and development

St John, J. C., 2014, In : Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1840, 4, p. 1345 - 1354 10 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

The identification of mitochondrial DNA variants in glioblastoma multiforme

Yeung, K. Y. V., Dickinson, A., Donoghue, J. F., Polekhina, G., White, S., Grammatopoulos, D. K., McKenzie, M., Johns, T. G. & St John, J. C., 2014, In : Acta neuropathologica communications. 2, p. 1 - 21 21 p., 1.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2013

Assisted Reproductive Technologies: The Potential to Prevent the Transmission of Mutant mtDNA from One Generation to the Next

Kelly, R. D. W., Mahmud, A. & St John, J. C., 1 Jan 2013, Mitochondrial DNA, Mitochondria, Disease and Stem Cells. St John, J. C. (ed.). United States: Humana Press, p. 157-183 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

A tribute to somatic cell reprogrammers

St John, J. C., 2013, In : Molecular Human Reproduction. 19, 2, p. 55 - 56 2 p.

Research output: Contribution to journalLetterOther

From Pluripotency to Differentiation: The Role of mtDNA in Stem Cell Models of Mitochondrial Diseases

Facucho-Oliveira, J. M., Kulkarni, T., Machado-Oliveira, G. & St John, J. C., 1 Jan 2013, Mitochondrial DNA, Mitochondria, Disease and Stem Cells. St John, J. C. (ed.). United States: Humana Press, p. 87-118 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Mitochondrial DNA, Mitochondria, Disease and Stem Cells

St John, J. C., 1 Jan 2013, New York, United States: Humana Press. 189 p.

Research output: Book/ReportEdited BookOtherpeer-review

49 Citations (Scopus)

Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells

Kelly, R. D. W., Rodda, A. E., Dickinson, A., Mahmud, A., Nefzger, C., Lee, W., Forsythe, J. S., Polo, J. M., Trounce, I. A., McKenzie, M., Nisbet, D. R. & St John, J. C., 2013, In : Stem Cells. 31, 4, p. 703 - 716 14 p.

Research output: Contribution to journalArticleResearchpeer-review

The Control of Mitochondrial DNA Replication in Gametes, Embryos and Early Development

St John, J. C., 2013, In : Australian Biochemist. 44, 1, p. 10 - 13 4 p.

Research output: Contribution to journalLetterOther

36 Citations (Scopus)

The effects of nuclear reprogramming on mitochondrial DNA replication

Kelly, R. D. W., Sumer, H., McKenzie, M., Facucho-Oliveira, J. M., Trounce, I. A., Verma, P. J. & St John, J. C., 2013, In : Stem Cell Reviews. 9, 1, p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

The regulation of mitochondrial DNA copy number in glioblastoma cells

Dickinson, A., Yeung, V. K. Y., Donoghue, J. F., Baker, M. J., Kelly, R. D. W., McKenzie, M., Johns, T. G. & St John, J. C., 2013, In : Cell Death and Differentiation. 20, 12, p. 1644 - 1653 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The Role of Mitochondrial DNA in Tumorigenesis

Yeung, V. K. Y., Dickinson, A. & St John, J. C., 1 Jan 2013, Mitochondrial DNA, Mitochondria, Disease and Stem Cells. St John, J. C. (ed.). United States: Humana Press, p. 119-155 37 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2012
94 Citations (Scopus)

Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A

Kelly, R. D. W., Mahmud, A., McKenzie, M., Trounce, I. & St John, J. C., 2012, In : Nucleic Acids Research. 40, 20, p. 10124 - 10138 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

The consequences of reprogramming a somatic cell for mitochondrial DNA transmission, inheritance and replication

St John, J. & Campbell, K., 1 Jan 2012, Nuclear Reprogramming and Stem Cells. Ainscough, J., Yamanaka, S. & Tada, T. (eds.). New York, United States: Humana Press, p. 83-97 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

21 Citations (Scopus)

Transmission, inheritance and replication of mitochondrial DNA in mammals: implications for reproductive processes and infertility

St John, J. C., 2012, In : Cell and Tissue Research. 349, 3, p. 795 - 808 14 p.

Research output: Contribution to journalArticleResearchpeer-review