Projects per year
Personal profile
Biography
Justin works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Senior Research Fellow.
A/Prof Justin Hamilton is an ARC Future Fellow at the Australian Centre for Blood Diseases (Melbourne, Australia). His group studies the role of platelets, platelet thrombin receptors, and their signaling effectors, in haemostasis, thrombosis, and inflammatory conditions. Justin received his PhD from the Department of Pharmacology at The University of Melbourne, where he was awarded the Chancellor's Prize in Medicine for the best PhD thesis of 2001. He then performed post-doctoral studies as a NHMRC CJ Martin Fellow in Prof. Shaun Coughlin's laboratory at the University of California, San Francisco, before returning to Australia to start his own research group. His work has been published in numerous journals, including Nature, Nature Communications, PNAS, Blood, and Circulation Research, and is funded by the NHMRC and ARC.
Research area keywords
- Cardiovascular Diseases
- Platelets
- Protease-Activated Receptors
- Thrombosis
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
Projects
- 14 Finished
-
Inhibition of the platelet thrombin receptor PAR4 to prevent thrombosis in coronary artery disease
Hamilton, J. (Primary Chief Investigator (PCI)) & Chen, V. (Chief Investigator (CI))
1/01/20 → 31/12/23
Project: Research
-
Development of a Microfluidic Blood Platelet Analyser
Nesbitt, W. (Primary Chief Investigator (PCI)), Mitchell, A. (Chief Investigator (CI)), Nandurkar, H. (Chief Investigator (CI)), Hamilton, J. (Chief Investigator (CI)), Thompson, P. (Chief Investigator (CI)), Tran, H. (Chief Investigator (CI)), Elliott, S. (Chief Investigator (CI)) & Macfarlane, I. (Chief Investigator (CI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/19 → 31/07/23
Project: Research
-
Targeting a novel anti-platelet mechanism for improved anti-thrombotic therapy
Hamilton, J. (Primary Chief Investigator (PCI)), Thompson, P. (Chief Investigator (CI)), Nandurkar, H. (Chief Investigator (CI)), Andrews, R. (Chief Investigator (CI)) & Nesbitt, W. (Chief Investigator (CI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/18 → 31/12/21
Project: Research
-
Proof-of-concept studies for a novel anti-thrombotic agent
Hamilton, J. (Primary Chief Investigator (PCI)), Sleeman, M. (Chief Investigator (CI)) & Nandurkar, H. (Chief Investigator (CI))
1/01/18 → 31/12/20
Project: Research
-
Generation and proof-of-concept testing of novel therapies for improved heart attack and stroke prevention
Hamilton, J. (Primary Chief Investigator (PCI)) & Sleeman, M. (Chief Investigator (CI))
1/01/17 → 31/12/17
Project: Research
-
Finding and following: a deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo
McGovern, A. S., Larsson, P., Tarlac, V., Setiabakti, N., Shabani Mashcool, L., Hamilton, J. R., Boknäs, N. & Nunez-Iglesias, J., 2024, In: Platelets. 35, 1, 10 p., 2344512.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Link opens in a new tab Citations (Scopus) -
Megakaryocytes possess a STING pathway that is transferred to platelets to potentiate activation
El-Mortada, F., Landelouci, K., Bertrand-Perron, S., Aubé, F. A., Poirier, A., Bidias, A., Jourdi, G., Welman, M., Gantier, M. P., Hamilton, J. R., Kile, B., Lordkipanidzé, M. & Pépin, G., 1 Feb 2024, In: Life Science Alliance. 7, 2, 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Link opens in a new tab Citations (Scopus) -
PI3KC2α inhibition is antithrombotic in blood from hypercholesterolemic mice
Setiabakti, N. M., Tarlac, V., Larsson, P. & Hamilton, J. R., Jan 2024, In: Journal of Thrombosis and Haemostasis. 22, 1, p. 249-254 6 p.Research output: Contribution to journal › Article › Research › peer-review
2 Link opens in a new tab Citations (Scopus) -
An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients
Zainal Abidin, N. A., Poon, E. K. W., Szydzik, C., Timofeeva, M., Akbaridoust, F., Brazilek, R. J., Tovar Lopez, F. J., Ma, X., Lav, C., Marusic, I., Thompson, P. E., Mitchell, A., Ooi, A. S. H., Hamilton, J. R. & Nesbitt, W. S., Dec 2022, In: BMC Biology. 20, 1, 22 p., 73.Research output: Contribution to journal › Article › Research › peer-review
Open Access18 Link opens in a new tab Citations (Scopus) -
A pilot clinical study to Evaluate Liraglutide-mediated Anti-platelet activity in patients with type-2 Diabetes (ELAID study)
Loganathan, J., Cohen, A. C., Kaloupis, G. M., Harris, C., Chronopoulos, A., James, V., Hamilton, J., Green, S., Wallis, A., Morgan, S., Dauer, R., Gilfillan, C. & Dear, A. E., May 2022, In: Journal of Diabetes and its Complications. 36, 5, 8 p., 108188.Research output: Contribution to journal › Article › Research › peer-review
13 Link opens in a new tab Citations (Scopus)