Projects per year
Personal profile
Biography
Justin works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Senior Research Fellow.
A/Prof Justin Hamilton is an ARC Future Fellow at the Australian Centre for Blood Diseases (Melbourne, Australia). His group studies the role of platelets, platelet thrombin receptors, and their signaling effectors, in haemostasis, thrombosis, and inflammatory conditions. Justin received his PhD from the Department of Pharmacology at The University of Melbourne, where he was awarded the Chancellor's Prize in Medicine for the best PhD thesis of 2001. He then performed post-doctoral studies as a NHMRC CJ Martin Fellow in Prof. Shaun Coughlin's laboratory at the University of California, San Francisco, before returning to Australia to start his own research group. His work has been published in numerous journals, including Nature, Nature Communications, PNAS, Blood, and Circulation Research, and is funded by the NHMRC and ARC.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Cardiovascular Diseases
- Platelets
- Protease-Activated Receptors
- Thrombosis
Collaborations and top research areas from the last five years
Projects
- 14 Finished
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Inhibition of the platelet thrombin receptor PAR4 to prevent thrombosis in coronary artery disease
Hamilton, J. & Chen, V.
1/01/20 → 31/12/23
Project: Research
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Development of a Microfluidic Blood Platelet Analyser
Nesbitt, W., Mitchell, A. A., Nandurkar, H., Hamilton, J., Thompson, P., Tran, H., Elliott, S. & Macfarlane, I.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/07/23
Project: Research
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Targeting a novel anti-platelet mechanism for improved anti-thrombotic therapy
Hamilton, J., Thompson, P., Nandurkar, H., Andrews, R. & Nesbitt, W.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/18 → 31/12/21
Project: Research
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Proof-of-concept studies for a novel anti-thrombotic agent
Hamilton, J., Sleeman, M. & Nandurkar, H.
1/01/18 → 31/12/20
Project: Research
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Targeting oxidant-dependent pathways to improve stroke outcomes in COPD
Vlahos, R., Bozinovski, S., Crack, P. J., Miller, A., Hamilton, J., Irving, L. B. & Steinfort, D. P.
1/01/17 → 31/12/20
Project: Research
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An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients
Zainal Abidin, N. A., Poon, E. K. W., Szydzik, C., Timofeeva, M., Akbaridoust, F., Brazilek, R. J., Tovar Lopez, F. J., Ma, X., Lav, C., Marusic, I., Thompson, P. E., Mitchell, A., Ooi, A. S. H., Hamilton, J. R. & Nesbitt, W. S., Dec 2022, In: BMC Biology. 20, 1, 22 p., 73.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus) -
A pilot clinical study to Evaluate Liraglutide-mediated Anti-platelet activity in patients with type-2 Diabetes (ELAID study)
Loganathan, J., Cohen, A. C., Kaloupis, G. M., Harris, C., Chronopoulos, A., James, V., Hamilton, J., Green, S., Wallis, A., Morgan, S., Dauer, R., Gilfillan, C. & Dear, A. E., May 2022, In: Journal of Diabetes and its Complications. 36, 5, 8 p., 108188.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists with Platelet PAR (Protease-Activated Receptor)-1 and PAR-4-Mediated Thrombin Resistance
Gnanenthiran, S. R., Pennings, G. J., Reddel, C. J., Campbell, H., Kockx, M., Hamilton, J. R., Chen, V. M. & Kritharides, L., 1 Aug 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 8, p. 960-972 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand
Stoller, M. L., Basak, I., Denorme, F., Rowley, J. W., Alsobrooks, J., Parsawar, K., Nieman, M. T., Yost, C. C., Hamilton, J. R., Bray, P. F. & Campbell, R. A., 12 Apr 2022, In: Blood Advances. 6, 7, p. 2303-2308 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Phosphoinositide 3‐Kinases as Potential Targets for Thrombosis Prevention
Setiabakti, N. M., Larsson, P. & Hamilton, J. R., 1 May 2022, In: International Journal of Molecular Sciences. 23, 9, 14 p., 4840.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access5 Citations (Scopus)