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Personal profile

Biography

Justin works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Senior Research Fellow.

A/Prof Justin Hamilton is an ARC Future Fellow at the Australian Centre for Blood Diseases (Melbourne, Australia). His group studies the role of platelets, platelet thrombin receptors, and their signaling effectors, in haemostasis, thrombosis, and inflammatory conditions. Justin received his PhD from the Department of Pharmacology at The University of Melbourne, where he was awarded the Chancellor's Prize in Medicine for the best PhD thesis of 2001. He then performed post-doctoral studies as a NHMRC CJ Martin Fellow in Prof. Shaun Coughlin's laboratory at the University of California, San Francisco, before returning to Australia to start his own research group. His work has been published in numerous journals, including Nature, Nature CommunicationsPNAS, Blood, and Circulation Research, and is funded by the NHMRC and ARC.

Keywords

  • Cardiovascular Diseases
  • Platelets
  • Protease-Activated Receptors
  • Thrombosis

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Projects 2001 2021

Research Output 1998 2019

Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood

Szydzik, C., Brazilek, R. J., Akbaridoust, F., De Silva, C., Moon, M., Marusic, I., Ooi, A. S. H., Nandurkar, H. H., Hamilton, J. R., Mitchell, A. & Nesbitt, W. S., 20 Aug 2019, In : Analytical Chemistry. 91, 16, p. 10830-10839 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The mode of anesthesia influences outcome in mouse models of arterial thrombosis

Sashindranath, M., Sturgeon, S., French, S. L., Craenmehr, D. D. D., Selan, C., Freddi, S., Johnson, C., Cody, S., Nesbitt, W., Hamilton, J., Cody, S. H., Nesbitt, W., Hamilton, J. & Nandurkar, H., Apr 2019, In : Thrombosis and Haemostasis. 3, 2, p. 197-206 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition

Selvadurai, M. V., Brazilek, R. J., Moon, M. J., Rinckel, J. Y., Eckly, A., Gachet, C., Meikle, P. J., Nandurkar, H. H., Nesbitt, W. S. & Hamilton, J. R., 1 Jan 2019, In : FEBS Letters. 593, 1, p. 88-96 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant

French, S. L., Thalmann, C., Bray, P. F., Macdonald, L. E., Murphy, A. J., Sleeman, M. W. & Hamilton, J. R., 12 Jun 2018, In : Blood Advances. 2, 11, p. 1283-1293 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Perinatal lethality of Par4–/– mice delivered by primiparous dams reveals spontaneous bleeding in mice without platelet thrombin receptor function

French, S. L. & Hamilton, J. R., 17 Feb 2018, In : Platelets. 29, 2, p. 196-198 3 p.

Research output: Contribution to journalArticleResearchpeer-review