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Research area keywords

  • Developmental Biology
  • Kidney
  • Heart
  • Mouse model

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

Functional genomics and gene-environment interaction highlight the complexity of Congenital Heart Disease caused by Notch pathway variants

Chapman, G., Moreau, J. L. M., Ip, E., Szot, J. O., Iyer, K. R., Shi, H., Yam, M. X., O’Reilly, V. C., Enriquez, A., Greasby, J. A., Alankarage, D., Martin, E. M. M. A., Hanna, B. C., Edwards, M., Monger, S., Blue, G. M., Winlaw, D. S., Ritchie, H. E., Grieve, S. M., Giannoulatou, E. & 2 others, Sparrow, D. B. & Dunwoodie, S. L., 15 Feb 2020, In : Human Molecular Genetics. 29, 4, p. 566-579 14 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Gene-environment interaction impacts on heart development and embryo survival

Moreau, J. L. M., Kesteven, S., Martin, E. M. M. A., Lau, K. S., Yam, M. X., O'Reilly, V. C., Del Monte-Nieto, G., Baldini, A., Feneley, M. P., Moon, A. M., Harvey, R. P., Sparrow, D. B., Chapman, G. & Dunwoodie, S. L., 20 Feb 2019, In : Development (Cambridge). 146, 4, 13 p., dev172957.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

NAD deficiency, congenital malformations, and niacin supplementation

Shi, H., Enriquez, A., Rapadas, M., Martin, E. M. M. A., Wang, R., Moreau, J., Lim, C. K., Szot, J. O., Ip, E., Hughes, J. N., Sugimoto, K., Humphreys, D. T., McInerney-Leo, A. M., Leo, P. J., Maghzal, G. J., Halliday, J., Smith, J., Colley, A., Mark, P. R., Collins, F. & 13 others, Sillence, D. O., Winlaw, D. S., Ho, J. W. K., Guillemin, G. J., Brown, M. A., Kikuchi, K., Thomas, P. Q., Stocker, R., Giannoulatou, E., Chapman, G., Duncan, E. L., Sparrow, D. B. & Dunwoodie, S. L., 10 Aug 2017, In : The New England Journal of Medicine. 377, 6, p. 544-552 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
58 Citations (Scopus)

Gestational stress induces the unfolded protein response, resulting in heart defects

Shi, H., O’Reilly, V. C., Moreau, J. L. M., Bewes, T. R., Yam, M. X., Chapman, B. E., Grieve, S. M., Stocker, R., Graham, R. M., Chapman, G., Sparrow, D. B. & Dunwoodie, S. L., 15 Jul 2016, In : Development (Cambridge). 143, 14, p. 2561-2572 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
21 Citations (Scopus)

Notch1 endocytosis is induced by ligand and is required for signal transduction

Chapman, G., Major, J. A., Iyer, K., James, A. C., Pursglove, S. E., Moreau, J. L. M. & Dunwoodie, S. L., Jan 2016, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 1, p. 166-177 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)