Research output per year
Research output per year
Personal profile
Biography
My work is principally focused on events central to infection and immunity. Specifically I work on deducing the structural arrangement of Killer-Cell Immunoglobulin-like Receptors (KIR) and their ligands and detail the molecular mode of interaction generating their complexes. This has important implications in disease and transplant outcomes. I also investigate immune reactions to specific drugs. This work is intended to lead to the better design and screening of new therapeutics.
Research area keywords
- Structural Biology
- Immunology
- Innate Immunity
- Receptors and Signal Transduction
- Drug hypersensitivity
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Research output
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Structural integrity with functional plasticity: what type I IFN receptor polymorphisms reveal
de Weerd, N. A., Vivian, J. P., Lim, S. S., Huang, S. U-S. & Hertzog, P. J., Sep 2020, In : Journal of leukocyte biology. 108, 3, p. 909-924 16 p.Research output: Contribution to journal › Review Article › Research › peer-review
1 Citation (Scopus) -
The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function
Saunders, P. M., MacLachlan, B. J., Pymm, P., Illing, P. T., Deng, Y., Wong, S. C., Oates, C. V. L., Purcell, A. W., Rossjohn, J., Vivian, J. P. & Brooks, A. G., 26 May 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 21, p. 11636-11647 12 p., A63.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Downregulation of MHC Class I Expression by Influenza A and B Viruses
Koutsakos, M., McWilliam, H. E. G., Aktepe, T. E., Fritzlar, S., Illing, P. T., Mifsud, N. A., Purcell, A. W., Rockman, S., Reading, P. C., Vivian, J. P., Rossjohn, J., Brooks, A. G., Mackenzie, J. M., Mintern, J. D., Villadangos, J. A., Nguyen, T. H. O. & Kedzierska, K., 29 May 2019, In : Frontiers in Immunology. 10, 12 p., 1158.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile8 Citations (Scopus) -
A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands
Faridi, P., Li, C., Ramarathinam, S. H., Vivian, J. P., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Hertzog, P. J., Ternette, N., Rossjohn, J., Croft, N. P. & Purcell, A. W., 12 Oct 2018, In : Science Immunology. 3, 28, 12 p., eaar3947.Research output: Contribution to journal › Article › Research › peer-review
48 Citations (Scopus) -
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome
Illing, P. T., Pymm, P., Croft, N. P., Hilton, H. G., Jojic, V., Han, A. S., Mendoza, J. L., Mifsud, N. A., Dudek, N. L., McCluskey, J., Parham, P., Rossjohn, J., Vivian, J. P. & Purcell, A. W., 8 Nov 2018, In : Nature Communications. 9, 1, 13 p., 4693.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile8 Citations (Scopus)