1974 …2020

Research output per year

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Research Output

2020

The EngCP endo α-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections

Cheung, J. K., Adams, V., D'Souza, D., James, M., Day, C. J., Jennings, M. P., Lyras, D. & Rood, J. I., Feb 2020, In : International Journal of Medical Microbiology. 310, 2, 12 p., 151398.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The Tcp plasmids of Clostridium perfringens require the resP gene to ensure stable inheritance

Revitt-Mills, S., Lao, C., Archambault, M., Lyras, D., Rood, J. I. & Adams, V., Jan 2020, In : Plasmid. 107, 11 p., 102461.

Research output: Contribution to journalArticleResearchpeer-review

Two putative zinc metalloproteases contribute to the virulence of Clostridium perfringens strains that cause avian necrotic enteritis

Wade, B., Keyburn, A. L., Haring, V., Ford, M., Rood, J. I. & Moore, R. J., Mar 2020, In : Journal of Veterinary Diagnostic Investigation. 32, 2, p. 259-267 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)
2019

Clostridial genetics: Genetic manipulation of the pathogenic Clostridia

Kuehne, S., Rood, J. I. & Lyras, D., Jun 2019, In : Microbiology spectrum. 7, 3, 16 p., GPP3-0040-2018.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Editorial

Top, E. M., Traxler, B. & Rood, J. I., 1 Sep 2019, In : Plasmid. 105, 1 p., 102437.

Research output: Contribution to journalEditorialOtherpeer-review

Erratum: Correction for Kennan et al., "Genomic Evidence for a Globally Distributed, Bimodal Population in the Ovine Footrot Pathogen Dichelobacter nodosus" (mBio (2014) 5 5 (e01821-e01814) PII: e02560-19)

Kennan, R. M., Gilhuus, M., Frosth, S., Seemann, T., Dhungyel, O. P., Whittington, R. J., Boyce, J. D., Powell, D. R., Aspán, A., Jørgensen, H. J., Bulach, D. M. & Rood, J. I., 29 Oct 2019, In : mBio. 10, 5, 1 p., e02560-19.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Histotoxic clostridial infections

Nagahama, M., Takehara, M. & Rood, J. I., Jul 2019, In : Microbiology spectrum. 7, 4, 17 p., GPP3-0024-2018.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

pCP13, a representative of a new family of conjugative toxin plasmids in Clostridium perfringens

Watts, T. D., Vidor, C. J., Awad, M. M., Lyras, D., Rood, J. I. & Adams, V., 1 Mar 2019, In : Plasmid. 102, p. 37-45 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Virulence Plasmids of the Pathogenic Clostridia

Revitt-Mills, S. A., Vidor, C. J., Watts, T. D., Lyras, D., Rood, J. I. & Adams, V., 17 May 2019, In : Microbiology spectrum. 7, 3, 28 p., GPP3-0034-2018.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2018

Antibiotic resistance plasmids and mobile genetic elements of Clostridium perfringens

Adams, V., Han, X., Lyras, D. & Rood, J. I., Sep 2018, In : Plasmid. 99, p. 32-39 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

5 Citations (Scopus)

Clostridium sordellii pathogenicity locus plasmid pCS1-1 encodes a novel clostridial conjugation locus

Vidor, C. J., Watts, T. D., Adams, V., Bulach, D., Couchman, E., Rood, J. I., Fairweather, N. F., Awad, M. & Lyras, D., 16 Jan 2018, In : mBio. 9, 1, 14 p., e01761-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Concurrent host-pathogen transcriptional responses in a clostridium perfringens murine myonecrosis infection

Low, L-Y., Harrison, P. F., Gould, J., Powell, D. R., Choo, J. M., Forster, S. C., Chapman, R., Gearing, L. J., Cheung, J. K., Hertzog, P. & Rood, J. I., 1 Mar 2018, In : mBio. 9, 2, 15 p., e00473-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3

Traore, D. A. K., Wisniewski, J. A., Flanigan, S. F., Conroy, P. J., Panjikar, S., Mok, Y-F., Lao, C., Griffin, M. D. W., Adams, V., Rood, J. I. & Whisstock, J. C., 13 Sep 2018, In : Nature Communications. 9, 1, 11 p., 3732.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Expansion of the Clostridium perfringens toxin-based typing scheme

Rood, J. I., Adams, V., Lacey, J. A., Lyras, D., McClane, B. A., Melville, S. B., Moore, R. J., Popoff, M. R., Sarker, M. R., Songer, J. G., Uzal, F. A. & Van Immerseel, F., 1 Oct 2018, In : Anaerobe. 53, p. 5-10 6 p.

Research output: Contribution to journalArticleResearchpeer-review

71 Citations (Scopus)

The incidence of Clostridioides difficile and Clostridium perfringens netF-positive strains in diarrheic dogs

Diniz, A. N., Coura, F. M., Rupnik, M., Adams, V., Stent, T. L., Rood, J. I., de Oliveira, C. A., Lobato, F. C. F. & Silva, R. O. S., 1 Feb 2018, In : Anaerobe. 49, p. 58-62 5 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Vibrational spectroscopy combined with transcriptomic analysis for investigation of bacterial responses towards acid stress

Hlaing, M. M., Wood, B. R., McNaughton, D., Rood, J. I., Fox, E. M. & Augustin, M. A., 1 Jan 2018, In : Applied Microbiology and Biotechnology. 102, 1, p. 333-343 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Whole genome analysis reveals the diversity and evolutionary relationships between necrotic enteritis-causing strains of Clostridium perfringens

Lacey, J. A., Allnutt, T. R., Vezina, B., Van, T. T. H., Stent, T., Han, X., Rood, J. I., Wade, B., Keyburn, A. L., Seemann, T., Chen, H., Haring, V., Johanesen, P. A., Lyras, D. & Moore, R. J., 22 May 2018, In : BMC Genomics. 19, 1, 22 p., 379.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)
2017

Bovine antibodies targeting primary and recurrent Clostridium difficile disease are a potent antibiotic alternative

Hutton, M. L., Cunningham, B. A., Mackin, K. E., Lyon, S. A., James, M. L., Rood, J. I. & Lyras, D., 16 Jun 2017, In : Scientific Reports. 7, 1, 13 p., 3665.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
16 Citations (Scopus)

Editorial

Rood, J. I., Thomas, C. M. & Top, E. M., 1 May 2017, In : Plasmid. 91, p. 1 1 p.

Research output: Contribution to journalEditorialOtherpeer-review

6 Citations (Scopus)

The Tcp conjugation system of Clostridium perfringens

Wisniewski, J. A. & Rood, J. I., 1 May 2017, In : Plasmid. 91, p. 28-36 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

15 Citations (Scopus)
2016

Analysis of the virulence-associated RevSR two-component signal transduction system of Clostridium perfringens

Cheung, J. K., Wisniewski, J. A., Adams, V. M., Quinsey, N. S. & Rood, J. I., Sep 2016, In : International Journal of Medical Microbiology. 306, 6, p. 429-442 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

CdtR regulates TcdA and TcdB production in Clostridium difficile

Lyon, S. A., Hutton, M. L., Rood, J. I., Cheung, J. K. & Lyras, D., 14 Jul 2016, In : PLoS Pathogens. 12, 7, 19 p., e1005758.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
26 Citations (Scopus)

Functional analysis of an feoB mutant in Clostridium perfringens strain 13

Awad, M. M., Cheung, J. K., Tan, J. E., McEwan, A. G., Lyras, D. & Rood, J. I., Oct 2016, In : Anaerobe. 41, p. 10-17 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

General Physiological and Virulence Properties of the Pathogenic Clostridia

Rood, J. I., 8 Apr 2016, Clostridial Diseases in Animals. Uzal, F. A., Songer, J. G., Prescott, J. F. & Popoff, M. R. (eds.). 1 ed. Chichester UK: Wiley-Blackwell, p. 7-12 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

NetB and necrotic enteritis: The hole movable story

Rood, J. I., Keyburn, A. L. & Moore, R. J., 31 May 2016, In : Avian Pathology. 45, 3, p. 295-301 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

19 Citations (Scopus)

RNA-seq analysis of virR and revR mutants of Clostridium perfringens

Low, L-Y., Harrison, P. F., Lin, Y-H., Boyce, J. D., Rood, J. I. & Cheung, J. K., 23 May 2016, In : BMC Genomics. 17, 14 p., 391.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

TcpM: a novel relaxase that mediates transfer of large conjugative plasmids from Clostridium perfringens

Wisniewski, J. A., Traore, D. A. K., Bannam, T. L., Lyras, D., Whisstock, J. C. & Rood, J. I., 1 Mar 2016, In : Molecular Microbiology. 99, 5, p. 884-896 13 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

The adherent abilities of Clostridium perfringens strains are critical for the pathogenesis of avian necrotic enteritis

Wade, B., Keyburn, A. L., Haring, V., Ford, M., Rood, J. I. & Moore, R. J., 25 Dec 2016, In : Veterinary Microbiology. 197, p. 53-61 9 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

The NEAT domain-containing proteins of Clostridium perfringens bind heme

Choo, J. M., Cheung, J. K., Wisniewski, J. A., Steer, D. L., Bulach, D. M., Hiscox, T. J., Chakravorty, A., Smith, A. I., Gell, D. A., Rood, J. I. & Awad, M. M., 16 Sep 2016, In : PLoS ONE. 11, 9, 26 p., 0162981.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)
2015

Animal models to study the pathogenesis of human and animal clostridium perfringens infections

Uzal, F. A., McClane, B. A., Cheung, J. K. T., Theoret, J. R., Garcia, J. P., Moore, R. J. & Rood, J. I., 2015, In : Veterinary Microbiology. 179, 1-2, p. 23 - 33 11 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

A two-component regulatory system modulates twitching motility in Dichelobacter nodosus

Kennan, R. M., Lovitt, C. J., Han, X. Y., Parker, D., Turnbull, L., Whitchurch, C. B. & Rood, J. I., 2015, In : Veterinary Microbiology. 179, 1-2, p. 34 - 41 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Binding of Clostridium perfringens to collagen correlates with the ability to cause necrotic enteritis in chickens

Wade, B., Keyburn, A. L., Seemann, T., Rood, J. I. & Moore, R. J., 2015, In : Veterinary Microbiology. 180, 3-4, p. 299 - 303 5 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Clostridium perfringens extracellular toxins and enzymes: 20 and counting

Revitt-Mills, S. A., Rood, J. I. & Adams, V., 2015, In : Microbiology Australia. 36, 3, p. 114-117 4 p.

Research output: Contribution to journalArticleOther

Clostridium perfringens type A-E toxin plasmids

Freedman, J. C., Theoret, J. R., Wisniewski, J. A., Uzal, F. A., Rood, J. I. & McClane, B. A., 2015, In : Research in Microbiology. 166, 5, p. 264 - 279 16 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Comparative neuropathology of ovine enterotoxemia produced by clostridium perfringens type D wild-type strain CN1020 and its genetically modified derivatives

Garcia, J. P., Giannitti, F., Finnie, J. W., Manavis, J., Beingesser, J., Adams, V. M., Rood, J. I. & Uzal, F. A., 2015, In : Veterinary Pathology. 52, 3, p. 465 - 475 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Correction for Chen et al., Epsilon-Toxin Production by Clostridium perfringens Type D Strain CN3718 Is Dependent upon the agr Operon but Not the VirS/VirR Two-Component Regulatory System

Chen, J., Rood, J. I. & McClane, B. A., 2015, In : mBio. 6, 1, 1 p., e02491-14.

Research output: Contribution to journalArticleOtherpeer-review

Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during clostridium difficile Infections

Carter, G. P., Chakravorty, A., Nguyen, T. A. P., Mileto, S., Schreiber, F., Li, L., Howarth, P., Clare, S., Cunningham, B., Sambol, S. P., Cheknis, A. K., Figueroa, I., Johnson, S., Gerding, D., Rood, J. I., Dougan, G., Lawley, T. D. & Lyras, D., 2015, In : mBio. 6, 3, p. 1 - 10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
104 Citations (Scopus)

Functional analysis of a bacitracin resistance determinant located on ICECp1, a novel Tn916-like element from a conjugative plasmid in Clostridium perfringens

Han, X. Y., Du, X-D., Southey, L. C., Bulach, D. M., Seemann, T., Yan, X., Bannam, T. L. & Rood, J. I., 2015, In : Antimicrobial Agents and Chemotherapy. 59, 11, p. 6855 - 6865 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
15 Citations (Scopus)

Genomic analyses of Clostridium perfringens isolates from five toxinotypes

Hassan, K. A., Elbourne, L. D. H., Tetu, S. G., Melville, S. B., Rood, J. I. & Paulsen, I. T., 2015, In : Research in Microbiology. 166, 4, p. 255 - 263 9 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

International Society for Plasmid Biology

Rood, J., Jensen, S. O., Lyras, D. & Top, E. M., 1 Jul 2015, In : Plasmid. 80, p. iv

Research output: Contribution to journalArticleOtherpeer-review

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Mackin, K. E., Elliott, B., Kotsanas, D., Howden, B. P., Carter, G. P., Korman, T. M., Riley, T. V., Rood, J. I., Jenkin, G. A. & Lyras, D., 2015, In : Anaerobe. 34, p. 80 - 83 4 p.

Research output: Contribution to journalArticleOtherpeer-review

6 Citations (Scopus)

NanR, a transcriptional regulator that binds to the promoters of genes involved in sialic acid metabolism in the anaerobic pathogen clostridium perfringens

Therit, B. H., Cheung, J. K. L., Rood, J. I. & Melville, S. B., 2015, In : PLoS ONE. 10, 7 , 17 p., e0133217.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

Plasmid partitioning systems of conjugative plasmids from Clostridium perfringens

Adams, V., Watts, T. D., Bulach, D. M., Lyras, D. & Rood, J. I., 2015, In : Plasmid. 80, p. 90-96 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX

Headey, S. J., Sivakumaran, A., Adams, V., Lyras, D., Rood, J. I., Scanlon, M. & Wilce, M. C. J., 2015, In : Journal of Molecular Recognition. 28, 5, p. 316-324 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The pore-forming alpha-toxin from clostridium septicum activates the MAPK pathway in a Ras-c-Raf-dependent and independent manner

Chakravorty, A., Awad, M. M., Cheung, J. K. T., Hiscox, T. J., Lyras, D. & Rood, J. I., 2015, In : Toxins. 7, 2, p. 516 - 534 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
11 Citations (Scopus)

Two novel membrane proteins, TcpD and TcpE, are essential for conjugative transfer of pCW3 in clostridium perfringens

Wisniewski, J. A., Teng, S. W. L., Bannam, T. L. & Rood, J. I., 2015, In : Journal of Bacteriology. 197, 4, p. 774 - 781 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
15 Citations (Scopus)
2014

ClostPath 2013 meeting on The Molecular Biology and Pathogenesis of the Clostridia special issue

Lyras, D. & Rood, J. I., 2014, In : Anaerobe. 30, p. 183 - 183 1 p.

Research output: Contribution to journalLetterOther

2 Citations (Scopus)

Detection of an en masse and reversible B- to A-DNA conformational transition in prokaryotes in response to desiccation

Whelan, D. R., Hiscox, T. J., Rood, J. I., Bambery, K. R., McNaughton, D. & Wood, B. R., 2014, In : Journal of the Royal Society Interface. 11, 97, p. 1 - 6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Genomic evidence for a Globally distributed, Bimodal population in the Ovine footrot pathogen dichelobacter nodosus

Kennan, R. M., Gilhuus, M., Frosth, S., Seemann, T., Dhungyel, O. P., Whittington, R. J., Boyce, J. D., Powell, D. R., Aspan, A., Jorgensen, H. J., Bulach, D. M. & Rood, J. I., 2014, In : mBio. 5, 5, p. 1 - 11 11 p., e01821-14.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
24 Citations (Scopus)