Projects per year
Personal profile
Biography
Prof Julian Rood is Professor of Microbiology at Monash University. His research has focused on the genetics and pathogenesis of anaerobic bacteria, particularly the pathogenic clostridia and the ovine footrot pathogen Dichelobacter nodosus. His research group has been responsible for the development of many of the genetic tools that are used to study these important bacteria. His current research interests are centered upon Clostridium perfringens, which causes disease in both humans and domestic livestock. This research is focused on the role of toxins in disease pathogenesis, the regulation of toxin and virulence gene expression and the mechanism by which conjugative antibiotic resistance and toxin plasmids can move between C. perfringens strains. His work on D. nodosus involves the use of reverse vaccinology to develop a cross-protective footrot vaccine. He is a Fellow of the American Academy of Microbiology, a Fellow and Life Member of the Australian Society for Microbiology and a Past-President of the Australian Society for Microbiology.
Research area keywords
- bacterial pathogenesis
- Anaerobic bacteria
- Clostridium perfringens
- Clostridial toxins
- Plasmids
- Conjugation
- Bacterial genetics
- Bacterial gene regulation
- Bacterial genomics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Mechanism of action of a novel multifunctional bacterial secretion system
Lyras, D., McGowan, S. & Rood, J.
1/01/18 → 31/12/20
Project: Research
The Dichelobacter Nodosus Genome Project
Australian Genome Research Facility
5/04/00 → …
Project: Research
Global regulatory networks that control virulence in Clostridium perfringens
National Health & Medical Research Council (NHMRC)
1/01/17 → 31/12/19
Project: Research
Beckman Coulter Optima Analytical Ultracentrifuge (AUC)
Dunstone, M., Whisstock, J., Daly, R., Atkinson, S., Turner, S., Lithgow, T., Gras, S., Stone, M., Davidovich, C., Rood, J., Coulibaly, F., Wilce, J., Borg, N., McGowan, S., Buckle, A., Elmlund, D., Elmlund, H., Belousoff, M., Ellisdon, A., Law, R., Purcell, A., Cryle, M., Nold, M., Nold, C., Warr, C., Johnson, T., Henstridge, M., Aguilar, M., Stroud, D. & Ryan, M.
1/12/16 → 31/12/17
Project: Research
Research Output
The EngCP endo α-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections
Cheung, J. K., Adams, V., D'Souza, D., James, M., Day, C. J., Jennings, M. P., Lyras, D. & Rood, J. I., Feb 2020, In : International Journal of Medical Microbiology. 310, 2, 12 p., 151398.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
The Tcp plasmids of Clostridium perfringens require the resP gene to ensure stable inheritance
Revitt-Mills, S., Lao, C., Archambault, M., Lyras, D., Rood, J. I. & Adams, V., Jan 2020, In : Plasmid. 107, 11 p., 102461.Research output: Contribution to journal › Article › Research › peer-review
Two putative zinc metalloproteases contribute to the virulence of Clostridium perfringens strains that cause avian necrotic enteritis
Wade, B., Keyburn, A. L., Haring, V., Ford, M., Rood, J. I. & Moore, R. J., 10 Jan 2020, (Accepted/In press) In : Journal of Veterinary Diagnostic Investigation. 9 p.Research output: Contribution to journal › Article › Research › peer-review
Clostridial genetics: Genetic manipulation of the pathogenic Clostridia
Kuehne, S., Rood, J. I. & Lyras, D., Jun 2019, In : Microbiology spectrum. 7, 3, 16 p., GPP3-0040-2018.Research output: Contribution to journal › Article › Research › peer-review
Editorial
Top, E. M., Traxler, B. & Rood, J. I., 1 Sep 2019, In : Plasmid. 105, 1 p., 102437.Research output: Contribution to journal › Editorial › Other › peer-review
Activities
- 1 Membership of industry collaboration/ network
Monash Antimicrobial Resistance Group (Event)
Trevor Lithgow (Chair/Co-Chair), Max Cryle (Member), Kellie Tuck (Member), Ana Traven (Member), Thomas Naderer (Member), Julian Rood (Member), Dena Lyras (Member), Anton Peleg (Member), Mibel Aguilar (Member), Fasseli Coulibaly (Member), Sheena McGowan (Member), Meredith Anne Okeeffe (Member), Matthew Belousoff (Member), Philip Heraud (Member)1 Mar 2017 → 1 Jan 2019
Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network