Projects per year
Personal profile
Biography
Prof Julian Rood is Professor of Microbiology at Monash University. His research has focused on the genetics and pathogenesis of anaerobic bacteria, particularly the pathogenic clostridia and the ovine footrot pathogen Dichelobacter nodosus. His research group has been responsible for the development of many of the genetic tools that are used to study these important bacteria. His current research interests are centered upon Clostridium perfringens, which causes disease in both humans and domestic livestock. This research is focused on the role of toxins in disease pathogenesis, the regulation of toxin and virulence gene expression and the mechanism by which conjugative antibiotic resistance and toxin plasmids can move between C. perfringens strains. His work on D. nodosus involves the use of reverse vaccinology to develop a cross-protective footrot vaccine. He is a Fellow of the American Academy of Microbiology, a Fellow and Life Member of the Australian Society for Microbiology and a Past-President of the Australian Society for Microbiology.
Research area keywords
- bacterial pathogenesis
- Anaerobic bacteria
- Clostridium perfringens
- Clostridial toxins
- Plasmids
- Conjugation
- Bacterial genetics
- Bacterial gene regulation
- Bacterial genomics
Network
Projects
-
The Dichelobacter Nodosus Genome Project
Australian Genome Research Facility
5/04/00 → …
Project: Research
-
Mechanism of action of a novel multifunctional bacterial secretion system
Lyras, D., McGowan, S. & Rood, J.
1/01/18 → 31/12/20
Project: Research
-
Beckman Coulter Optima Analytical Ultracentrifuge (AUC)
Dunstone, M., Whisstock, J., Daly, R., Atkinson, S., Turner, S., Lithgow, T., Gras, S., Stone, M., Davidovich, C., Rood, J., Coulibaly, F., Wilce, J., Borg, N., McGowan, S., Buckle, A., Elmlund, D., Elmlund, H., Belousoff, M., Ellisdon, A., Law, R., Purcell, A., Cryle, M., Nold, M., Nold, C., Warr, C., Johnson, T., Henstridge, M., Aguilar, M., Stroud, D. & Ryan, M.
1/12/16 → 31/12/17
Project: Research
Research output
-
Cardiopulmonary Lesions in Sheep Produced by Experimental Acute Clostridium Perfringens Type D Enterotoxemia
Giannitti, F., García, J. P., Rood, J. I., Adams, V., Armendano, J. I., Beingesser, J. & Uzal, F. A., 15 Oct 2020, (Accepted/In press) In : Veterinary Pathology. 11 p.Research output: Contribution to journal › Article › Research › peer-review
-
The EngCP endo α-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections
Cheung, J. K., Adams, V., D'Souza, D., James, M., Day, C. J., Jennings, M. P., Lyras, D. & Rood, J. I., Feb 2020, In : International Journal of Medical Microbiology. 310, 2, 12 p., 151398.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
The ever-expanding tcp conjugation locus of pCW3 from Clostridium perfringens
Revitt-Mills, S. A., Watts, T. D., Lyras, D., Adams, V. & Rood, J. I., 9 Jun 2020, (Accepted/In press) In : Plasmid. 12 p., 102516.Research output: Contribution to journal › Article › Research › peer-review
-
The Tcp plasmids of Clostridium perfringens require the resP gene to ensure stable inheritance
Revitt-Mills, S., Lao, C., Archambault, M., Lyras, D., Rood, J. I. & Adams, V., Jan 2020, In : Plasmid. 107, 11 p., 102461.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Two putative zinc metalloproteases contribute to the virulence of Clostridium perfringens strains that cause avian necrotic enteritis
Wade, B., Keyburn, A. L., Haring, V., Ford, M., Rood, J. I. & Moore, R. J., Mar 2020, In : Journal of Veterinary Diagnostic Investigation. 32, 2, p. 259-267 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile3 Citations (Scopus)
Activities
- 1 Membership of industry collaboration/ network
-
Monash Antimicrobial Resistance Group (Event)
Trevor Lithgow (Chair/Co-Chair), Max Cryle (Member), Kellie Tuck (Member), Ana Traven (Member), Thomas Naderer (Member), Julian Rood (Member), Dena Lyras (Member), Anton Peleg (Member), Mibel Aguilar (Member), Fasseli Coulibaly (Member), Sheena McGowan (Member), Meredith Anne Okeeffe (Member), Matthew Belousoff (Member) & Philip Heraud (Member)
1 Mar 2017 → 1 Jan 2019Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network