Projects per year
Personal profile
Biography
Prof Julian Rood is Professor of Microbiology at Monash University. His research has focused on the genetics and pathogenesis of anaerobic bacteria, particularly the pathogenic clostridia and the ovine footrot pathogen Dichelobacter nodosus. His research group has been responsible for the development of many of the genetic tools that are used to study these important bacteria. His current research interests are centered upon Clostridium perfringens, which causes disease in both humans and domestic livestock. This research is focused on the role of toxins in disease pathogenesis, the regulation of toxin and virulence gene expression and the mechanism by which conjugative antibiotic resistance and toxin plasmids can move between C. perfringens strains. His work on D. nodosus involves the use of reverse vaccinology to develop a cross-protective footrot vaccine. He is a Fellow of the American Academy of Microbiology, a Fellow and Life Member of the Australian Society for Microbiology and a Past-President of the Australian Society for Microbiology.
Keywords
- bacterial pathogenesis
- Anaerobic bacteria
- Clostridium perfringens
- Clostridial toxins
- Plasmids
- Conjugation
- Bacterial genetics
- Bacterial gene regulation
- Bacterial genomics
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Projects 2000 2019
Global regulatory networks that control virulence in Clostridium perfringens
National Health & Medical Research Council (NHMRC)
1/01/17 → 31/12/19
Project: Research
The Dichelobacter Nodosus Genome Project
Australian Genome Research Facility
5/04/00 → …
Project: Research
Research Output 1982 2019
pCP13, a representative of a new family of conjugative toxin plasmids in Clostridium perfringens
Watts, T. D., Vidor, C. J., Awad, M. M., Lyras, D., Rood, J. I. & Adams, V., 1 Mar 2019, In : Plasmid. 102, p. 37-45 9 p.Research output: Contribution to journal › Article › Research › peer-review
Antibiotic resistance plasmids and mobile genetic elements of Clostridium perfringens
Adams, V., Han, X., Lyras, D. & Rood, J. I., 26 Jul 2018, (Accepted/In press) In : Plasmid. 8 p.Research output: Contribution to journal › Article › Research › peer-review
Clostridium sordellii pathogenicity locus plasmid pCS1-1 encodes a novel clostridial conjugation locus
Vidor, C. J., Watts, T. D., Adams, V., Bulach, D., Couchman, E., Rood, J. I., Fairweather, N. F., Awad, M. & Lyras, D., 16 Jan 2018, In : mBio. 9, 1, 14 p., e01761-17.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Concurrent host-pathogen transcriptional responses in a clostridium perfringens murine myonecrosis infection
Low, L-Y., Harrison, P. F., Gould, J., Powell, D. R., Choo, J. M., Forster, S. C., Chapman, R., Gearing, L. J., Cheung, J. K., Hertzog, P. & Rood, J. I., 1 Mar 2018, In : mBio. 9, 2, 15 p., e00473-18.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
Traore, D. A. K., Wisniewski, J. A., Flanigan, S. F., Conroy, P. J., Panjikar, S., Mok, Y-F., Lao, C., Griffin, M. D. W., Adams, V., Rood, J. I. & Whisstock, J. C., 13 Sep 2018, In : Nature Communications. 9, 1, 11 p., 3732.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Activities 2017 2017
- 1 Membership of industry collaboration/ network
Monash Biomedicine Discovery Institute (Organisational unit)
Trevor Lithgow (Inventor), Matthew James Belousoff (Member), Meredith Anne O'Keeffe (Member), Max Cryle (Member), Ana Traven (Member), John Dallas Boyce (Member), Julian Ian Rood (Member), Fasseli Joseph Coulibaly (Member), Anton Yariv Peleg (Member), Sheena McGowan (Member), Dena Lyras (Member), Philip Robert Heraud (Member)2017 → 2018
Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network