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Personal profile

Biography

Prof Julian Rood is Professor of Microbiology at Monash University. His research has focused on the genetics and pathogenesis of anaerobic bacteria, particularly the pathogenic clostridia and the ovine footrot pathogen Dichelobacter nodosus. His research group has been responsible for the development of many of the genetic tools that are used to study these important bacteria. His current research interests are centered upon Clostridium perfringens, which causes disease in both humans and domestic livestock. This research is focused on the role of toxins in disease pathogenesis, the regulation of toxin and virulence gene expression and the mechanism by which conjugative antibiotic resistance and toxin plasmids can move between C. perfringens strains. His work on D. nodosus involves the use of reverse vaccinology to develop a cross-protective footrot vaccine. He is a Fellow of the American Academy of Microbiology, a Fellow and Life Member of the Australian Society for Microbiology and a Past-President of the Australian Society for Microbiology.

Keywords

  • bacterial pathogenesis
  • Anaerobic bacteria
  • Clostridium perfringens
  • Clostridial toxins
  • Plasmids
  • Conjugation
  • Bacterial genetics
  • Bacterial gene regulation
  • Bacterial genomics

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Projects 2000 2020

Research Output 1974 2019

Clostridial genetics: Genetic manipulation of the pathogenic Clostridia

Kuehne, S., Rood, J. I. & Lyras, D., Jun 2019, In : Microbiology spectrum. 7, 3, 16 p., GPP3-0040-2018.

Research output: Contribution to journalArticleResearchpeer-review

Histotoxic clostridial infections

Nagahama, M., Takehara, M. & Rood, J. I., Jul 2019, In : Microbiology spectrum. 7, 4, 17 p., GPP3-0024-2018.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

pCP13, a representative of a new family of conjugative toxin plasmids in Clostridium perfringens

Watts, T. D., Vidor, C. J., Awad, M. M., Lyras, D., Rood, J. I. & Adams, V., 1 Mar 2019, In : Plasmid. 102, p. 37-45 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Virulence Plasmids of the Pathogenic Clostridia

Revitt-Mills, S. A., Vidor, C. J., Watts, T. D., Lyras, D., Rood, J. I. & Adams, V., 17 May 2019, In : Microbiology spectrum. 7, 3, 28 p., GPP3-0034-2018.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Antibiotic resistance plasmids and mobile genetic elements of Clostridium perfringens

Adams, V., Han, X., Lyras, D. & Rood, J. I., Sep 2018, In : Plasmid. 99, p. 32-39 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Activities 2017 2017

  • 1 Membership of industry collaboration/ network

Monash Antimicrobial Resistance Group (Event)

Trevor Lithgow (Chair/Co-Chair), Max Cryle (Member), Kellie Tuck (Member), Ana Traven (Member), Thomas Naderer (Member), Julian Rood (Member), Dena Lyras (Member), Anton Peleg (Member), Mibel Aguilar (Member), Fasseli Coulibaly (Member), Sheena McGowan (Member), Meredith Anne Okeeffe (Member), Matthew Belousoff (Member), Philip Heraud (Member)
1 Mar 2017

Activity: Industry, Government and Philanthropy Engagement and PartnershipsMembership of industry collaboration/ network