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Personal profile

Biography

Prof Julian Rood is Professor of Microbiology at Monash University. His research has focused on the genetics and pathogenesis of anaerobic bacteria, particularly the pathogenic clostridia and the ovine footrot pathogen Dichelobacter nodosus. His research group has been responsible for the development of many of the genetic tools that are used to study these important bacteria. His current research interests are centered upon Clostridium perfringens, which causes disease in both humans and domestic livestock. This research is focused on the role of toxins in disease pathogenesis, the regulation of toxin and virulence gene expression and the mechanism by which conjugative antibiotic resistance and toxin plasmids can move between C. perfringens strains. His work on D. nodosus involves the use of reverse vaccinology to develop a cross-protective footrot vaccine. He is a Fellow of the American Academy of Microbiology, a Fellow and Life Member of the Australian Society for Microbiology and a Past-President of the Australian Society for Microbiology.

Keywords

  • bacterial pathogenesis
  • Anaerobic bacteria
  • Clostridium perfringens
  • Clostridial toxins
  • Plasmids
  • Conjugation
  • Bacterial genetics
  • Bacterial gene regulation
  • Bacterial genomics

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Projects 2000 2019

Research Output 1982 2019

pCP13, a representative of a new family of conjugative toxin plasmids in Clostridium perfringens

Watts, T. D., Vidor, C. J., Awad, M. M., Lyras, D., Rood, J. I. & Adams, V., 1 Mar 2019, In : Plasmid. 102, p. 37-45 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Antibiotic resistance plasmids and mobile genetic elements of Clostridium perfringens

Adams, V., Han, X., Lyras, D. & Rood, J. I., 26 Jul 2018, (Accepted/In press) In : Plasmid. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Clostridium sordellii pathogenicity locus plasmid pCS1-1 encodes a novel clostridial conjugation locus

Vidor, C. J., Watts, T. D., Adams, V., Bulach, D., Couchman, E., Rood, J. I., Fairweather, N. F., Awad, M. & Lyras, D., 16 Jan 2018, In : mBio. 9, 1, 14 p., e01761-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Concurrent host-pathogen transcriptional responses in a clostridium perfringens murine myonecrosis infection

Low, L-Y., Harrison, P. F., Gould, J., Powell, D. R., Choo, J. M., Forster, S. C., Chapman, R., Gearing, L. J., Cheung, J. K., Hertzog, P. & Rood, J. I., 1 Mar 2018, In : mBio. 9, 2, 15 p., e00473-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3

Traore, D. A. K., Wisniewski, J. A., Flanigan, S. F., Conroy, P. J., Panjikar, S., Mok, Y-F., Lao, C., Griffin, M. D. W., Adams, V., Rood, J. I. & Whisstock, J. C., 13 Sep 2018, In : Nature Communications. 9, 1, 11 p., 3732.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Activities 2017 2017

  • 1 Membership of industry collaboration/ network

Monash Biomedicine Discovery Institute (Organisational unit)

Trevor Lithgow (Inventor), Matthew James Belousoff (Member), Meredith Anne O'Keeffe (Member), Max Cryle (Member), Ana Traven (Member), John Dallas Boyce (Member), Julian Ian Rood (Member), Fasseli Joseph Coulibaly (Member), Anton Yariv Peleg (Member), Sheena McGowan (Member), Dena Lyras (Member), Philip Robert Heraud (Member)
20172018

Activity: Industry, Government and Philanthropy Engagement and PartnershipsMembership of industry collaboration/ network