Dr Bosco completed his Bachelor of Medicine and Bachelor of Surgery with Honours in 2002 at the University of New South Wales. From 2007 - 2011 he trained in Clinical Immunology/Allergy and Immunopathology in New South Wales and Victoria, at the Westmead and Royal Melbourne Hospitals.

Since being awarded his Fellowship with the Royal Australasian College of Physicians and Royal College of Pathologists of Australasia in 2011, Dr Bosco has held Clinical Immunology and Allergy consultant positions at both the Royal Victorian Eye and Ear and the Alfred Hospitals. He also works as a consultant Immunologist and Allergist with Epworth Allergy Specialists and as an Immunopathologist with Alfred Pathology. He completed his PhD on the immunoregulatory properties of CD52 at the Walter Eliza Hall Institute of Medical Research.