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Research Output 1997 2019

2019

Characterising an Alternative Murine Model of Diabetic Cardiomyopathy

Tate, M., Prakoso, D., Willis, A. M., Peng, C., Deo, M., Qin, C. X., Walsh, J. L., Nash, D. M., Cohen, C. D., Rofe, A. K., Sharma, A., Kiriazis, H., Donner, D. G., De Haan, J. B., Watson, A. M. D., De Blasio, M. J. & Ritchie, R. H., 14 Nov 2019, In : Frontiers in Physiology. 10, 15 p., 1395.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018
1 Citation (Scopus)

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

Mathew, G., Sharma, A., Pickering, R. J., Rosado, C. J., Lemarie, J., Mudgal, J., Thambi, M., Sebastian, S., Jandeleit-Dahm, K. A., de Haan, J. B. & Unnikrishnan, M. K., 3 Oct 2018, In : Free Radical Research. 52, 10, p. 1140-1157 18 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Nrf2 activation is a potential therapeutic approach to attenuate diabetic retinopathy

Deliyanti, D., Alrashdi, S. F., Tan, S. M., Meyer, C., Ward, K. W., de Haan, J. B. & Wilkinson-Berka, J. L., 1 Feb 2018, In : Investigative Ophthalmology and Visual Science. 59, 2, p. 815-825 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
39 Citations (Scopus)

Oxidative stress and NLRP3-inflammasome activity as significant drivers of diabetic cardiovascular complications: Therapeutic implications

Sharma, A., Tate, M., Mathew, G., Vince, J. E., Ritchie, R. H. & De Haan, J. B., 20 Feb 2018, In : Frontiers in Physiology. 9, FEB, 15 p., 114.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
32 Citations (Scopus)

Recent novel approaches to limit oxidative stress and inflammation in diabetic complications

Pickering, R. J., Rosado, C. J., Sharma, A., Buksh, S., Tate, M. & de Haan, J. B., 1 Jan 2018, In : Clinical and Translational Immunology. 7, 4, 20 p., e1016.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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2017

Corrigendum to “Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium” [Vasc. Pharmacol. 79 (2016) 32–42](S1537189115002384)(10.1016/j.vph.2015.11.001)

Sharma, A., Yuen, D., Huet, O., Pickering, R., Stefanovic, N., Bernatchez, P. & de Haan, J. B., 1 Dec 2017, In : Vascular Pharmacology. 99, p. 83-83 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

4 Citations (Scopus)

Does lack of glutathione peroxidase 1 gene expression exacerbate lung injury induced by neonatal hyperoxia in mice?

Bouch, S., O'Reilly, M., de Haan, J. B., Harding, R. & Sozo, F., 1 Jul 2017, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 1, p. L115-L125 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

JNK activation of BIM promotes hepatic oxidative stress, steatosis, and insulin resistance in obesity

Litwak, S. A., Pang, L., Galic, S., Igoillo-Esteve, M., Stanley, W. J., Turatsinze, J. V., Loh, K., Thomas, H. E., Sharma, A., Trepo, E., Moreno, C., Gough, D. J., Eizirik, D. L., De Haan, J. B. & Gurzov, E. N., 1 Dec 2017, In : Diabetes. 66, 12, p. 2973-2986 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Protective effect of inflammasome activation by hydrogen peroxide in a mouse model of septic shock

Huet, O., Pickering, R. J., Tikellis, C., Latouche, C., Long, F., Kingwell, B., Dickinson, B., Chang, C. J., Masters, S., Mackay, F., Cooper, M. E. & De Haan, J. B., 1 Feb 2017, In : Critical Care Medicine. 45, 2, p. e184-e194 11 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction

Sharma, A., Rizky, L., Stefanovic, N., Tate, M., Ritchie, R. H., Ward, K. W. & de Haan, J. B., 3 Mar 2017, In : Cardiovascular Diabetology. 16, 1, 13 p., 33.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)
2016
15 Citations (Scopus)

A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy

Deliyanti, D., Lee, J. Y., Petratos, S., Meyer, C. J., Ward, K., Wilkinson-Berka, J. & De Haan-Klein, J. B., 1 Aug 2016, In : Clinical Science. 130, 15, p. 1375-1387 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Erratum: Corrigendum to “Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice” (Atherosclerosis (2015) 243(2) (598–608) (S0021915015301805) (10.1016/j.atherosclerosis.2015.10.096))

Rasmiena, A. A., Barlow, C. K., Stefanovic, N., Huynh, K., Tan, R., Sharma, A., Tull, D., de Haan, J. B. & Meikle, P. J., 1 Nov 2016, In : Atherosclerosis. 254, p. 314-315 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

16 Citations (Scopus)

Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium

Sharma, A., Yuen, D., Huet, O., Pickering, R., Stefanovic, N., Bernatchez, P. & de Haan, J. B., 1 Apr 2016, In : Vascular Pharmacology. 79, p. 32-42 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2015
35 Citations (Scopus)

Are reactive oxygen species still the basis for diabetic complications?

Di Marco, E., Jha, J. C., Sharma, A., Wilkinson-Berka, J. L., Jandeleit-Dahm, K. A. & De Haan, J., 2015, In : Clinical Science. 129, 2, p. 199-216 18 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

25 Citations (Scopus)

Direct endothelial nitric oxide synthase activation provides atheroprotection in diabetes-accelerated atherosclerosis

Sharma, A., Sellers, S., Stefanovic, N., Leung, C., Tan, S., Huet, O., Granville, D. J., Cooper, M. E., De Haan-Klein, J. B. & Bernatchez, P., 2015, In : Diabetes. 64, 11, p. 3937-3950 14 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina

Tan, S. M., Deliyanti, D., Figgett, W. A., Talia, D. M., De Haan, J. B. & Wilkinson-Berka, J. L., 1 Jul 2015, In : Experimental Eye Research. 136, p. 1-8 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets

Stanley, W. J., Litwak, S. A., Quah, H. S., Tan, S. M., Kay, T. W. H., Tiganis, T., De Haan-Klein, J. B., Thomas, H. E. & Gurzov, E., 2015, In : Diabetes. 64, 7, p. 2489 - 2496 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Late-intervention study with ebselen in an experimental model of type 1 diabetic nephropathy

Tan, S. M., Sharma, A., Stefanovic, N. & de Haan, J. B., Mar 2015, In : Free Radical Research. 49, 3, p. 219-227 9 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Nanoporous metal-phenolic particles as ultrasound imaging probes for hydrogen peroxide

Guo, J., Wang, X., Henstridge, D. C., Richardson, J. J., Cui, J., Sharma, A., Febbraio, M. A., Peter, K., De Haan-Klein, J. B., Hagemeyer, C. E. & Caruso, F., 2015, In : Advanced Healthcare Materials. 4, 14, p. 2170 - 2175 6 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice

Rasmiena, A. A., Barlow, C. K., Stefanovic, N., Huynh, K., Tan, R., Sharma, A., Tull, D., de Haan, J. B. & Meikle, P. J., 1 Dec 2015, In : Atherosclerosis. 243, 2, p. 598-608 11 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Targeting mitochondria-and reactive oxygen species-driven pathogenesis in diabetic nephropathy

Lindblom, R. S. J., Higgins, G. C., Coughlan, M. T. & De Haan-Klein, J. B., 2015, In : The Review of Diabetic Studies. 12, 1-2, p. 134-156 23 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2014
48 Citations (Scopus)

Combating oxidative stress in diabetic complications with Nrf2 activators: How much is too much?

Tan, S. M. & de Haan, J. B., 2014, In : Redox Report. 19, 3, p. 107-117 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
58 Citations (Scopus)

Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-Associated atherosclerosis and improves diabetic kidney disease

Tan, S. M., Sharma, A., Stefanovic, N., Yuen, D. Y. C., Karagiannis, T. C., Meyer, C., Ward, K. W., Cooper, M. E. & De Haan, J. B., Sep 2014, In : Diabetes. 63, 9, p. 3091-3103 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Oxidative Stress in Surgery

Rosenfeldt, F., Wilson, M., Lee, G., Kure, C., Ou, R., Braun, L. & De Haan, J. B., 2014, Systems Biology of Free Radicals and Antioxidants. Laher, I. (ed.). Berlin Germany: Springer, p. 3929-3946 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2013
24 Citations (Scopus)

An Apolipoprotein A-I Mimetic Peptide Designed with a Reductionist Approach Stimulates Reverse Cholesterol Transport and Reduces Atherosclerosis in Mice

Ditiatkovski, M., D'Souza, W., Kesani, R., Chin-Dusting, J., de Haan, J. B., Remaley, A. & Sviridov, D., 9 Jul 2013, In : PLoS ONE. 8, 7, e68802.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
31 Citations (Scopus)

Ensuring animal welfare while meeting scientific aims using a murine pneumonia model of septic shock

Huet, O., Ramsey, D., Miljavec, S., Jenney, A., Aubron, C., Aprico, A., Stefanovic, N., Balkau, B., Head, G. A., de Haan, J. B. & Chin-Dusting, J. P. F., Jun 2013, In : Shock. 39, 6, p. 488-494 7 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Lack of the antioxidant glutathione peroxidase-1 (GPx1) exacerbates retinopathy of prematurity in mice

Tan, S., Stefanovic, N., Tan, G. M. L., Wilkinson-Berka, J. & de Haan, J. B., 1 Jan 2013, In : Investigative Ophthalmology and Visual Science. 54, 1, p. 555 - 562 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
204 Citations (Scopus)

NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis

Gray, S. P., Di Marco, E., Okabe, J., Szyndralewiez, C., Heitz, F., Montezano, A. C., De Haan-Klein, J. B., Koulis, C., El-Osta, A., Andrews, K. L., Chin-Dusting, J. PF., Touyz, R. M., Wingler, K., Cooper, M. E., Schmidt, H. & Jandeleit-Dahm, K. A. M., 2013, In : Circulation. 127, 18, p. 1888 - 1902 15 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Oxidative stress in surgery in an ageing population: pathophysiology and therapy

Rosenfeldt, F. L., Wilson, M. D., Lee, G. A., Kure, C., Ou, R., Braun, L. A. & de Haan, J., 2013, In : Experimental Gerontology. 48, 1, p. 45 - 54 10 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

The Modified Selenenyl Amide, M-hydroxy Ebselen, Attenuates Diabetic Nephropathy and Diabetes-Associated Atherosclerosis in ApoE/GPx1 Double Knockout Mice

Tan, S. M., Sharma, A., Yuen, D. Y. C., Stefanovic, N., Krippner, G., Mugesh, G., Chai, Z. & de Haan, J. B., 16 Jul 2013, In : PLoS ONE. 8, 7, e69193.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2012
9 Citations (Scopus)

Novel pathways and therapies in experimental diabetic atherosclerosis

Koulis, C., de Haan, J. B. & Allen, T. J., Mar 2012, In : Expert Review of Cardiovascular Therapy. 10, 3, p. 323-335 13 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Oxidative Stress and Novel Antioxidant Approaches to Reduce Diabetic Complications

Tan, S. M., Sharma, A. & de Haan, J. B., 2012, Oxidative Stress and Diseases, InTech. In-Tech

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Open Access
File

Vascular reactive oxygen species biology - Insights from transgenic and knockout mouse models

Tan, S. M. & De Haan, J. B., 1 May 2012, Systems Biology of Free Radicals and Antioxidants. Laher, I. (ed.). Berlin Germany: Springer-Verlag London Ltd., p. 1091-1122 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2011
15 Citations (Scopus)

Cell division autoantigen 1 enhances signaling and the profibrotic effects of transforming growth factor-beta in diabetic nephropathy

Tu, Y., Wu, T., Dai, A., Pham, Y., Chew, P., de Haan, J., Wang, Y., Toh, B-H., Zhu, H., Cao, Z., Cooper, M. & Chai, Z., 2011, In : Kidney International. 79, 2, p. 199 - 209 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Role of oxidative stress and targeted antioxidant therapies in experimental models of diabetic complications

Allen, T. J., de Haan, J. B. & Jandeleit-Dahm, K. A., 2011, Studies on Experimental Models. Basu, S. & Wiklund, L. (eds.). Humana Press, p. 3-38 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

26 Citations (Scopus)

Targeted antioxidant therapies in hyperglycemia-mediated endothelial dysfunction

Haan, J. B. D. & Cooper, M. E., 1 Jan 2011, In : Frontiers in Bioscience - Scholar. S3, p. 709-729 21 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2010
61 Citations (Scopus)

Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse

Chew, P., Yuen, D., Stefanovic, N., Pete, J., Coughlan, M. T., Jandeleit-Dahm, K., Thomas, M., Rosenfeldt, F., Cooper, M. & De Haan, J. B., 2010, In : Diabetes. 59, 12, p. 3198-3207 10 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo

Ballinger, M. L., Osman, N., Hashimura, K., De Haan, J. B., Jandeleit-Dahm, K. A., Ilen, T. A., Tannock, L., Rutledge, J. C. & Little, P. J., 2010, In : Journal of Cellular and Molecular Medicine. 14, 6B, p. 1408 - 1418 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
62 Citations (Scopus)

Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse

Chew, P., Yuen, D. Y. C., Koh, P., Stefanovic, N., Febbraio, M. A., Kola, I., Cooper, M. E. & de Haan, J. B., Jun 2009, In : Arteriosclerosis, Thrombosis and Vascular Biology. 29, 6, p. 823-830 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
1 Citation (Scopus)

Down syndrome, antioxidant balance and the 'gene dosage effect' hypothesis

De Haan-Klein, J. B., Crack, P. J., Pritchard, M. A. & Kola, I., 2007, Oxidative Stress and Neurodegenerative Disorders. Qureshi, G. A. & Parvez, S. H. (eds.). 1st ed. The Netherlands: Elsevier, p. 219 - 235 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

186 Citations (Scopus)

Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in diabetic apolipoprotein E-deficient mice

Lewis, P., Stefanovic, N., Pete, J., Calkin, A. C., Giunti, S., Thallas-Bonke, V., Jandeleit-Dahm, K. A., Allen, T. J., Kola, I., Cooper, M. E. & De Haan, J. B., 1 Apr 2007, In : Circulation. 115, 16, p. 2178-2187 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2006
43 Citations (Scopus)

Lack of the antioxidant glutathione peroxidase-1 does not increase atherosclerosis in C57BL/J6 mice fed a high-fat diet

De Haan, J. B., Witting, P. K., Stefanovic, N., Pete, J., Daskalakis, M., Kola, I., Stocker, R. & Smolich, J. J., 2006, In : Journal of Lipid Research. 47, 6, p. 1157 - 1167 11 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Retinal light damage: structural and functional effects of the antioxidant glutathione peroxidase-1

Gosbell, A. D., Stefanovic, N., Scurr, L. L., Pete, J., Kola, I., Favilla, I. & De Haan, J. B., 2006, In : Investigative Ophthalmology and Visual Science. 47, 6, p. 2613 - 2622 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
46 Citations (Scopus)

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

De Haan-Klein, J. B., Stefanovic, N., Nikolic-Paterson, D. J., Scurr, L. L., Croft, K. D., Mori, T. A., Hertzog, P. J., Kola, I., Atkins, R. C. & Tesch, G. H., 2005, In : American Journal of Physiology - Renal Physiology. 289, 3, p. F544 - F551 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
55 Citations (Scopus)

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

De Haan, J. B., Bladier, C., Lotfi-Miri, M., Taylor, J., Hutchinson, P., Crack, P. J., Hertzog, P. & Kola, I., 1 Jan 2004, In : Free Radical Biology and Medicine. 36, 1, p. 53-64 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2003
37 Citations (Scopus)

An altered antioxidant balance occurs in Down syndrome fetal organs: implications for the "gene dosage effect" hypothesis

De Haan-Klein, J. B., Susil, B., Pritchard, M. A. & Kola, I., 2003, In : Journal of Neural Transmission. 67, Suppl, p. 67 - 83 17 p.

Research output: Contribution to journalArticleResearchpeer-review

An imbalance in antioxidant defense affects cellular function: The pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

De Haan, J. B., Crack, P. J., Flentjar, N. J., Iannello, R. C., Hertzog, P. J. & Kola, I., 2003, In : Redox Report. 8, 2, p. 69 - 79 11 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

An imbalance in antioxidant defense aftfects cellular function: The pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

de Haan, J. B., Crack, P. J., Flentjar, N., Iannello, R. C., Hertzog, P. J. & Kola, I., 7 May 2003, In : Redox Report. 8, 2, p. 69-79 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

51 Citations (Scopus)

Glutathione peroxidase-1 contributes to the neuroprotection seen in the superoxide dismutase-1 transgenic mouse in response to ischemia/reperfusion injury

Crack, P. J., Taylor, J. M., De Haan, J. B., Kola, I., Hertzog, P. & Iannello, R. C., 1 Jan 2003, In : Journal of Cerebral Blood Flow and Metabolism. 23, 1, p. 19-22 4 p.

Research output: Contribution to journalArticleResearchpeer-review