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PhD projects

Characterising the interplay between coagulation factors and the brain during models of neuroinflammation

20202023

Research activity per year

Personal profile

Biography

Dr Josh Bourne is a Postdoctoral Researcher in the Monash Neuroinflammation group, investigating novel mechanisms and therapeutic targets to alleviate inflammation in the brain after ischaemic stroke. Dr Bourne completed his PhD in 2021 within the Platelet Group at the University of Birmingham (UK) working with Associate Professor Julie Rayes and Professor Steve Watson. Here, he characterised platelet receptor CLEC-2 in thrombosis and the inflammatory response, and successully published 6 first-author papers. During this time, he found passion in intravital microscopy, so relocated to Melbourne to train with world-leading intravitalist, Associate Professor Connie Wong. Dr Bourne now investigates the complex interplay between thrombosis, associated coagulation factors, and neuroinflammation. Since beginning his Postdoctoral position, he has acquired >$250,000 in competitive funding, and won awards at a national and international level.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 10 - Reduced Inequalities

Education/Academic qualification

Cardiovascular Science, PhD, Characterisation of platelet-receptor, CLEC-2, in thrombosis and inflammation, University of Birmingham

1 Oct 201830 Sept 2021

Award Date: 5 Dec 2022

Oncology, MSc, University of Nottingham

Award Date: 3 Dec 2018

Medical Physiology and Therapeutics, BSc (Hons), University of Nottingham

Award Date: 1 Jul 2016

Research area keywords

  • Innate Immunity
  • Thrombosis
  • Thromboinflammation
  • Inflammation
  • Stroke
  • Platelet biology
  • Macrophages
  • Macrophage polarisation
  • Microglia

Collaborations and top research areas from the last five years

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