Research output per year
Research output per year
Personal profile
Biography
Dr Josh Bourne is a NHMRC-funded Postdoctoral Research Fellow in the Neuroinflammation group, investigating novel mechanisms and therapeutic targets to alleviate inflammation in the brain after ischaemic stroke. He completed his PhD in 2021 with the Birmingham Platelet Group at the University of Birmingham (UK) in Cardiovascular Science, characterising platelet receptor CLEC-2 in thrombosis and the inflammatory response. Josh has first author publications in haematologica and Frontiers in Immunology, and has raised funds through the Heart Foundation's Vanguard grant toward advancement in stroke therapeutics (2022).
Education/Academic qualification
Cardiovascular Science, PhD, University of Birmingham
1 Oct 2018 → 30 Sep 2021
Award Date: 5 Dec 2022
Oncology, MSc, University of Nottingham
Award Date: 3 Dec 2018
Medical Physiology and Therapeutics, BSc (Hons), University of Nottingham
Award Date: 1 Jul 2016
Research area keywords
- Innate Immunity
- Thrombosis
- Thromboinflammation
- Inflammation
- Stroke
- Platelet biology
- Macrophages
- Macrophage polarisation
- Microglia
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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CLEC-2 supports platelet aggregation in mouse but not human blood at arterial shear
Bourne, J., Smith, C. W., Jooss, N. J., Di, Y., Brown, H. C., Montague, S. J., Thomas, M. R., Poulter, N. S., Rayes, J. & Watson, S. P., 11 Jul 2022, (Accepted/In press) In: Thrombosis and Haemostasis.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Preferential uptake of SARS-CoV-2 by pericytes potentiates vascular damage and permeability in an organoid model of the microvasculature
Khan, A. O., Reyat, J. S., Hill, H., Bourne, J. H., Colicchia, M., Newby, M. L., Allen, J. D., Crispin, M., Youd, E., Murray, P. G., Taylor, G., Stamataki, Z., Richter, A. G., Cunningham, A. F., Pugh, M. & Rayes, J., 16 Jun 2022, (Accepted/In press) In: Cardiovascular Research. 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Quantification of Leukocyte–Endothelial Cell Interaction During In Vitro Models of Thrombosis at Arterial and Venous Shear Rates
Bourne, J. H., 2022, Angiogenesis: Methods and Protocols. Benest, A. V. (ed.). New York USA: Humana Press, p. 287-295 9 p. (Methods in Molecular Biology; vol. 2441).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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S100A8/A9 drives the formation of procoagulant platelets through GPIbα
Colicchia, M., Schrottmaier, W. C., Perrella, G., Reyat, J. S., Begum, J., Slater, A., Price, J., Clark, J. C., Zhi, Z., Simpson, M. J., Bourne, J. H., Poulter, N. S., Khan, A. O., Nicolson, P. L. R., Pugh, M., Harrison, P., Iqbal, A. J., Rainger, G. E., Watson, S. P., Thomas, M. R., & 3 others, 26 Aug 2022, (Accepted/In press) In: Blood.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation
Krysko, O., Bourne, J. H., Kondakova, E., Galova, E. A., Whitworth, K., Newby, M. L., Bachert, C., Hill, H., Crispin, M., Stamataki, Z., Cunningham, A. F., Pugh, M., Khan, A. O., Rayes, J., Vedunova, M., Krysko, D. V. & Brill, A., 26 Sep 2022, In: Frontiers in Immunology. 13, 13 p., 968981.Research output: Contribution to journal › Article › Research › peer-review
Open Access