Personal profile

Biography

Position

Professor and Associate Dean, Graduate Research
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Delivery, Disposition and Dynamics
Monash Institute of Pharmaceutical Sciences

 

Joseph Nicolazzo graduated with a PhD in 2004 from Monash University (Australia) focusing on buccal mucosal drug delivery. He joined the Faculty of Pharmacy and Pharmaceutical Sciences, Monash University in 2007 as a Lecturer, where he is now a Professor and Associate Dean, Graduate Research. His research focuses on central nervous system (CNS) drug delivery, the role of drug transporters at the blood-brain barrier (BBB) in facilitating and limiting drug access into the CNS, how transport across the BBB alters in neurodegenerative diseases, and how the BBB may be exploited to reverse pathology associated with Alzheimer’s disease and amyotrophic lateral sclerosis. He is the author of 110 peer-reviewed manuscripts and is regularly invited to international conferences in the field of BBB biology, including Gordon Research Conference – Barriers of the CNS and International Conference on Cerebral Vascular Biology. Joseph is Immediate Past President of the Australasian Pharmaceutical Science Association, Editor of Pharmaceutical Research, and an Editorial Board Member of Journal of Pharmaceutical Sciences, International Journal of Pharmaceutics, Journal of Pharmacy and Pharmacology, and Fluids and Barriers of the CNS. He is a Steering Council Member of International Brain Barriers Society, Executive Committee Member of the Board of Pharmaceutical Sciences of International Pharmaceutical Federation (FIP), and has been induced as a Fellow of FIP.

Research interests

Using a suite of in vitro, in situ and in vivo models, my research is broadly classified into:

  • Understanding the factors affecting BBB transport of drugs and endogenous molecules
  • The involvement of intracellular trafficking proteins in facilitating molecular transport across the BBB
  • The impact of Alzheimer's disease and amyotrophic lateral sclerosis on BBB transport of drugs and endogenous molecules
  • Exploring molecular targets at the BBB that can be utilised to reverse cognitive dysfunction associated with Alzheimer's disease

Monash teaching commitment

Unit coordinator, PHR2021 (How Medicines Work III)

Lecturer

- PHR1022 (How Medicines Work II)

- PHR2021 (How Medicines Work III)

- BPS2041 (Drug Delivery and Pharmacokinetics)

 

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research area keywords

  • Alzheimer's Disease
  • Blood-Brain Barrier
  • CNS Drug Delivery
  • Drug Transport

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or