Projects per year
Personal profile
Biography
Position
Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences
Director, Australian Translational Medicinal Chemistry Facility
Research Theme Leader - Fragment library design for the ARC Industrial Transformation Training Centre
President, International Chemical Biology Society
Related Links:
- Baell Research Group
- Monash Institute of Pharmaceutical Sciences
- Australian Translational Medicinal Chemistry Facility - ATMCF
Research interests
- Molecular design
- Peptidomimetics
- Small molecule screening libraries and chemoinformatics
- Hit-to-lead and lead optimisation medicinal chemistry
- Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
- Pre-clinical development of new drug candidates
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Prodrug Development of Biased N-Alkylpyridazinones for the Acute Intravenous Treatment of Myocardial Ischaemia-Reperfusion Injury
Baell, J., Ritchie, R. H., Kirkpatrick, C., Figtree, G., Deora, G. & Qin, C. H.
1/01/19 → 31/12/20
Project: Research
Small molecule Inhibitors of glutathione transferase omega 1-1 (GSTO1-1) for the treatment of inflammatory disease
Baell, J., Board, P., Oakley, A. J., Casarotto, M. & Mujumdar, P.
1/01/19 → 31/12/21
Project: Research
Targeted development of AMPK β2-isoform allosteric activators
Oakhill, J., Baell, J. & Kemp, B. E.
1/01/18 → 31/12/21
Project: Research
Novel Radioligands for PET imaging and phenotyping of multiple sclerosis diagnosis
Baell, J., Kilpatrick, T. J., Binder, M. D., Vivash, L. & Ackermann, U.
1/01/18 → 31/12/20
Project: Research
Research Output
Action plan for hit identification (APHID): KAT6A as a case study
Yi, X., Xue, L., Thomas, T. & Baell, J. B., 1 Mar 2020, In : Future Medicinal Chemistry. 12, 5, p. 423-437 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
1
Citation
(Scopus)
Copper-catalyzed [4 + 2] annulation reaction of ß-enaminones and aryl diazonium salts without external oxidant: Synthesis of highly functionalized 3: H -1,2,4-triazines via homogeneous or heterogeneous strategy
Ding, Q., Li, M., Sun, Y., Yu, Y., Baell, J. B. & Huang, F., 7 Feb 2020, In : Organic Chemistry Frontiers. 7, 3, p. 457-463 7 p.Research output: Contribution to journal › Article › Research › peer-review
1
Citation
(Scopus)
Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors
Xie, Y., Tummala, P., Oakley, A. J., Deora, G. S., Nakano, Y., Rooke, M., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Casarotto, M. G., Board, P. G. & Baell, J. B., 26 Mar 2020, In : Journal of Medicinal Chemistry. 63, 6, p. 2894-2914 21 p.Research output: Contribution to journal › Article › Research › peer-review
Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi
Varghese, S., Rahmani, R., Russell, S., Deora, G. S., Ferrins, L., Toynton, A., Jones, A., Sykes, M., Kessler, A., Eufrásio, A., Cordeiro, A. T., Sherman, J., Rodriguez, A., Avery, V. M., Piggott, M. J. & Baell, J. B., 2020, In : ACS Medicinal Chemistry Letters. 11, 3, p. 278-285 8 p.Research output: Contribution to journal › Article › Research › peer-review
HBO1 is required for the maintenance of leukaemia stem cells
MacPherson, L., Anokye, J., Yeung, M. M., Lam, E. Y. N., Chan, Y. C., Weng, C. F., Yeh, P., Knezevic, K., Butler, M. S., Hoegl, A., Chan, K. L., Burr, M. L., Gearing, L. J., Willson, T., Liu, J., Choi, J., Yang, Y., Bilardi, R. A., Falk, H., Nguyen, N. & 28 others, , 9 Jan 2020, In : Nature. 577, p. 266–270 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2
Citations
(Scopus)
Prizes
2004 National Biota Prize for Medicinal Chemistry
Baell, Jonathan (Recipient), 2005
Prize: Prize (including medals and awards)
Monash University Research Award for the Faculty of Pharmacy and Pharmacology
Baell, Jonathan (Recipient), 2019
Prize: Prize (including medals and awards)
NHMRC Principal Research Fellow, Medicinal Chemistry
Baell, Jonathan (Recipient), 2017
Prize: Competitive Fellowships
Scientific Achievement Award in Drug Discovery and Development
Baell, Jonathan (Recipient), 2020
Prize: Prize (including medals and awards)