Personal profile

Biography

Position

Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences

 

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Research interests

  • Molecular design
  • Peptidomimetics
  • Small molecule screening libraries and chemoinformatics
  • Hit-to-lead and lead optimisation medicinal chemistry
  • Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
  • Pre-clinical development of new drug candidates

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2021

Novel Radioligands for PET imaging and phenotyping of multiple sclerosis diagnosis

Baell, J. B., Kilpatrick, T. J., Binder, M. D., Vivash, L. E. & Ackermann, U.

1/01/1831/12/20

Project: Research

Eliminating Visceral Leishmaniasis - An Australian-Indian Partnership

Baell, J. B., McConville, M. J., Talukdar, A. & Ganguly, D.

23/06/1723/06/20

Project: Research

New drugs against parasitic nematodes of livestock animals

Gasser, R. B., Baell, J. B., Jabbar, A., Hofmann, A., Wells, T., Burrows, J., Waterson, D. & Wilks, A. F.

29/05/1716/06/20

Project: Research

Compounds Australia - Enabling the Next Phase of Australian Drug Discovery

Poulsen, S., Martin, J. L., Avery, V. M., Quinn, R. J., Baell, J. B., Scanlon, M., Booker, G. W., Abell, A., Wang, S., Karuso, P., Guillemin, G. A., Smith, J. A., Ryan, J. H. & Peat, T. S.

Monash University – Internal University Contribution, Monash University – Internal School Contribution

10/03/179/03/18

Project: Research

Research Output 2003 2018

Open Access
File

8-Mercaptoguanine derivatives as inhibitors of dihydropteroate synthase

Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D. 2017 (Accepted/In press) In : Chemistry-A European Journal. 10 p.

Research output: Research - peer-reviewArticle

Optimization of 2-anilino 4-amino substituted quinazolines into potent antimalarial agents with oral in vivo activity

Gilson, P. R., Tan, C., Jarman, K. E., Lowes, K. N., Curtis, J. M., Nguyen, W., Di Rago, A. E., Bullen, H. E., Prinz, B., Duffy, S., Baell, J. B., Hutton, C. A., Jousset Subroux, H., Crabb, B. S., Avery, V. M., Cowman, A. F. & Sleebs, B. E. 9 Feb 2017 In : Journal of Medicinal Chemistry. 60, 3, p. 1171-1188 18 p.

Research output: Research - peer-reviewArticle

An alternative approach to the synthesis of peptides containing a cystathionine bridge

Harjani, J. R., Yap, B. K., Norton, R. S. & Baell, J. B. 9 Jun 2016 In : Tetrahedron. 72, 23, p. 3256-3261 6 p.

Research output: Research - peer-reviewArticle

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

Sutton, S. K., Carter, D. R., Kim, P., Tan, O., Arndt, G. M., Zhang, X. D., Baell, J., Noll, B. D., Wang, S., Kumar, N., McArthur, G. A., Cheung, B. B. & Marshall, G. M. 1 Aug 2016 In : OncoTarget. 7, 32, p. 52166-52178 13 p.

Research output: Research - peer-reviewArticle

Prizes

2004 National Biota Prize for Medicinal Chemistry

Jonathan Bayldon Baell (Recipient), 2005

Prize: Prize (including medals and awards)