Personal profile



Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences


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Research interests

  • Molecular design
  • Peptidomimetics
  • Small molecule screening libraries and chemoinformatics
  • Hit-to-lead and lead optimisation medicinal chemistry
  • Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
  • Pre-clinical development of new drug candidates

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Projects 2012 2021

Novel Radioligands for PET imaging and phenotyping of multiple sclerosis diagnosis

Baell, J. B., Kilpatrick, T. J., Binder, M. D., Vivash, L. E. & Ackermann, U.


Project: Research

Eliminating Visceral Leishmaniasis - An Australian-Indian Partnership

Baell, J. B., McConville, M. J., Talukdar, A. & Ganguly, D.


Project: Research

New drugs against parasitic nematodes of livestock animals

Gasser, R. B., Baell, J. B., Jabbar, A., Hofmann, A., Wells, T., Burrows, J., Waterson, D. & Wilks, A. F.


Project: Research

Novel therapeutics targeting neuronal transport pathways in MND

Atkins, J., Baell, J. B., Abbott, B., Laird, A. & Walker, A.


Project: Research

Research Output 1999 2018

Open Access

8-Mercaptoguanine derivatives as inhibitors of dihydropteroate synthase

Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D. 2017 (Accepted/In press) In : Chemistry-A European Journal. 10 p.

Research output: Research - peer-reviewArticle

Optimization of 2-anilino 4-amino substituted quinazolines into potent antimalarial agents with oral in vivo activity

Gilson, P. R., Tan, C., Jarman, K. E., Lowes, K. N., Curtis, J. M., Nguyen, W., Di Rago, A. E., Bullen, H. E., Prinz, B., Duffy, S., Baell, J. B., Hutton, C. A., Jousset Subroux, H., Crabb, B. S., Avery, V. M., Cowman, A. F. & Sleebs, B. E. 9 Feb 2017 In : Journal of Medicinal Chemistry. 60, 3, p. 1171-1188 18 p.

Research output: Research - peer-reviewArticle

An alternative approach to the synthesis of peptides containing a cystathionine bridge

Harjani, J. R., Yap, B. K., Norton, R. S. & Baell, J. B. 9 Jun 2016 In : Tetrahedron. 72, 23, p. 3256-3261 6 p.

Research output: Research - peer-reviewArticle

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

Sutton, S. K., Carter, D. R., Kim, P., Tan, O., Arndt, G. M., Zhang, X. D., Baell, J., Noll, B. D., Wang, S., Kumar, N., McArthur, G. A., Cheung, B. B. & Marshall, G. M. 1 Aug 2016 In : OncoTarget. 7, 32, p. 52166-52178 13 p.

Research output: Research - peer-reviewArticle

Open Access


2004 National Biota Prize for Medicinal Chemistry

Jonathan Bayldon Baell (Recipient), 2005

Prize: Prize (including medals and awards)