Jonathan Baell


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Personal profile



Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences


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Research interests

  • Molecular design
  • Peptidomimetics
  • Small molecule screening libraries and chemoinformatics
  • Hit-to-lead and lead optimisation medicinal chemistry
  • Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
  • Pre-clinical development of new drug candidates

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Projects 2012 2021

Targeted development of AMPK β2-isoform allosteric activators

Oakhill, J., Baell, J. B. & Kemp, B. E.


Project: Research

Novel Radioligands for PET imaging and phenotyping of multiple sclerosis diagnosis

Baell, J. B., Kilpatrick, T. J., Binder, M. D., Vivash, L. E. & Ackermann, U.


Project: Research

Eliminating Visceral Leishmaniasis - An Australian-Indian Partnership

Baell, J. B., McConville, M. J., Talukdar, A. & Ganguly, D.


Project: Research

Research Output 1998 2018

1,2,4-Oxadiazole antimicrobials act synergistically with daptomycin and display rapid kill kinetics against MDR Enterococcus faecium

Carter, G. P., Harjani, J. R., Li, L., Pitcher, N. P., Nong, Y., Riley, T. V., Williamson, D. A., Stinear, T. P., Baell, J. B. & Howden, B. P. 1 Jun 2018 In : Journal of Antimicrobial Chemotherapy. 73, 6, p. 1562-1569 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D. 6 Feb 2018 In : Chemistry - A European Journal. 24, 8, p. 1922-1930 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens

Nguyen, N., Wilson, D. W., Nagalingam, G., Triccas, J. A., Schneider, E. K., Li, J., Velkov, T. & Baell, J. 25 Mar 2018 In : European Journal of Medicinal Chemistry. 148, p. 507-518 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening

Thomas, D. R., Lundberg, L., Pinkham, C., Shechter, S., DeBono, A., Baell, J., Wagstaff, K. M., Hick, C. A., Kehn-Hall, K. & Jans, D. A. 1 Mar 2018 In : Antiviral Research. 151, p. 8-19 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access


2004 National Biota Prize for Medicinal Chemistry

Jonathan Bayldon Baell (Recipient), 2005

Prize: Prize (including medals and awards)