Jonathan Baell


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Personal profile



Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences


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Research interests

  • Molecular design
  • Peptidomimetics
  • Small molecule screening libraries and chemoinformatics
  • Hit-to-lead and lead optimisation medicinal chemistry
  • Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
  • Pre-clinical development of new drug candidates

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Projects 2012 2021

Novel Radioligands for PET imaging and phenotyping of multiple sclerosis diagnosis

Baell, J. B., Kilpatrick, T. J., Binder, M. D., Vivash, L. E. & Ackermann, U.


Project: Research

Targeted development of AMPK β2-isoform allosteric activators

Oakhill, J., Baell, J. B. & Kemp, B. E.


Project: Research

Eliminating Visceral Leishmaniasis - An Australian-Indian Partnership

Baell, J. B., McConville, M. J., Talukdar, A. & Ganguly, D.


Project: Research

New drugs against parasitic nematodes of livestock animals

Gasser, R. B., Baell, J. B., Jabbar, A., Hofmann, A., Wells, T., Burrows, J., Waterson, D. & Wilks, A. F.


Project: Research

Research Output 1999 2018

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D. 6 Feb 2018 In : Chemistry - A European Journal. 24, 8, p. 1922-1930 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens

Nguyen, N., Wilson, D. W., Nagalingam, G., Triccas, J. A., Schneider, E. K., Li, J., Velkov, T. & Baell, J. 25 Mar 2018 In : European Journal of Medicinal Chemistry. 148, p. 507-518 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening

Thomas, D. R., Lundberg, L., Pinkham, C., Shechter, S., DeBono, A., Baell, J., Wagstaff, K. M., Hick, C. A., Kehn-Hall, K. & Jans, D. A. 1 Mar 2018 In : Antiviral Research. 151, p. 8-19 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

Jiao, Y., Preston, S., Song, H., Jabbar, A., Liu, Y., Baell, J., Hofmann, A., Hutchinson, D., Wang, T., Koehler, A. V., Fisher, G. M., Andrews, K. T., Laleu, B., Palmer, M. J., Burrows, J. N., Wells, T. N. C., Wang, Q. & Gasser, R. B. 31 May 2017 In : Parasites and Vectors. 10, 1, 272

Research output: Contribution to journalArticleResearchpeer-review

Open Access


2004 National Biota Prize for Medicinal Chemistry

Jonathan Bayldon Baell (Recipient), 2005

Prize: Prize (including medals and awards)