Projects per year
Personal profile
Biography
Position
Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences
Related Links:
- Baell Research Group
- Monash Institute of Pharmaceutical Sciences
- Australian Translational Medicinal Chemistry Facility - ATMCF
Research interests
- Molecular design
- Peptidomimetics
- Small molecule screening libraries and chemoinformatics
- Hit-to-lead and lead optimisation medicinal chemistry
- Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
- Pre-clinical development of new drug candidates
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2021
Small molecule Inhibitors of glutathione transferase omega 1-1 (GSTO1-1) for the treatment of inflammatory disease
Baell, J. B., Board, P., Oakley, A. J., Casarotto, M. & Mujumdar, P. P.
1/01/19 → 31/12/21
Project: Research
Prodrug Development of Biased N-Alkylpyridazinones for the Acute Intravenous Treatment of Myocardial Ischaemia-Reperfusion Injury
Baell, J. B., Ritchie, R. H., Kirkpatrick, C. M. J., Figtree, G., Deora, G. S. & Qin, C.
1/01/19 → 31/12/20
Project: Research
Transactivation of RAGE: a novel therapeutic target in type 1 diabetes
Thomas, M. C., Baell, J. B., Rosado, C. J. & Dimitropoulos, A.
1/10/18 → 31/03/20
Project: Research
Male contraception through pharmacological blockade of sperm transport
Ventura, S., Baell, J. B., Charman, S. A. & Sexton, P.
1/08/18 → 31/05/20
Project: Research
Research Output 1998 2018
1,2,4-Oxadiazole antimicrobials act synergistically with daptomycin and display rapid kill kinetics against MDR Enterococcus faecium
Carter, G. P., Harjani, J. R., Li, L., Pitcher, N. P., Nong, Y., Riley, T. V., Williamson, D. A., Stinear, T. P., Baell, J. B. & Howden, B. P., 1 Jun 2018, In : Journal of Antimicrobial Chemotherapy. 73, 6, p. 1562-1569 8 p.Research output: Contribution to journal › Article › Research › peer-review
8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase
Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D., 6 Feb 2018, In : Chemistry - A European Journal. 24, 8, p. 1922-1930 9 p.Research output: Contribution to journal › Article › Research › peer-review
Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery
Coussens, N. P., Sittampalam, G. S., Guha, R., Brimacombe, K., Grossman, A., Chung, T. D. Y., Weidner, J. R., Riss, T., Trask, O. J., Auld, D., Dahlin, J. L., Devanaryan, V., Foley, T. L., McGee, J., Kahl, S. D., Kales, S. C., Arkin, M., Baell, J., Bejcek, B., Gal-Edd, N. & 25 others, 1 Sep 2018, In : Clinical and Translational Science. 11, 5, p. 461-470 10 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access
File
Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens
Nguyen, N., Wilson, D. W., Nagalingam, G., Triccas, J. A., Schneider, E. K., Li, J., Velkov, T. & Baell, J., 25 Mar 2018, In : European Journal of Medicinal Chemistry. 148, p. 507-518 12 p.Research output: Contribution to journal › Article › Research › peer-review
Correspondence: Reply to 'Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury'
Qin, C. X., May, L. T., Sexton, P. M., DeBono, A. J., Baell, J. B., Christopoulos, A. & Ritchie, R. H., 1 Dec 2018, In : Nature Communications. 9, 1, 4 p., 530.Research output: Contribution to journal › Letter › Other › peer-review
Open Access
File
Prizes
2004 National Biota Prize for Medicinal Chemistry
Jonathan Bayldon Baell (Recipient), 2005
Prize: Prize (including medals and awards)