Projects per year
Personal profile
Biography
Position
Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences
Related Links:
- Baell Research Group
- Monash Institute of Pharmaceutical Sciences
- Australian Translational Medicinal Chemistry Facility - ATMCF
Research interests
- Molecular design
- Peptidomimetics
- Small molecule screening libraries and chemoinformatics
- Hit-to-lead and lead optimisation medicinal chemistry
- Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
- Pre-clinical development of new drug candidates
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2021
Small molecule Inhibitors of glutathione transferase omega 1-1 (GSTO1-1) for the treatment of inflammatory disease
Baell, J., Board, P., Oakley, A. J., Casarotto, M. & Mujumdar, P.
1/01/19 → 31/12/21
Project: Research
Prodrug Development of Biased N-Alkylpyridazinones for the Acute Intravenous Treatment of Myocardial Ischaemia-Reperfusion Injury
Baell, J., Ritchie, R. H., Kirkpatrick, C., Figtree, G., Deora, G. & Qin, H.
1/01/19 → 31/12/20
Project: Research
Transactivation of RAGE: a novel therapeutic target in type 1 diabetes
Thomas, M., Baell, J., Rosado, C. & Dimitropoulos, A.
1/10/18 → 31/03/20
Project: Research
Male contraception through pharmacological blockade of sperm transport
Ventura, S., Baell, J., Charman, S. & Sexton, P.
1/08/18 → 31/05/20
Project: Research
Research Output 1998 2019
3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity
Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 others, , 1 Jan 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2485-2498 14 p.Research output: Contribution to journal › Article › Research › peer-review
Contemporary Anti-Ebola Drug Discovery Approaches and Platforms
Schneider-Futschik, E. K., Hoyer, D., Khromykh, A. A., Baell, J. B., Marsh, G. A., Baker, M. A., Li, J. & Velkov, T., 1 Nov 2019, In : ACS Infectious Diseases. 5, 1, p. 35-48 14 p.Research output: Contribution to journal › Article › Research › peer-review
Novel 1-Methyl-1 H-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic Activity
Le, T. G., Kundu, A., Ghoshal, A., Nguyen, N. H., Preston, S., Jiao, Y., Ruan, B., Xue, L., Huang, F., Keiser, J., Hofmann, A., Chang, B. C. H., Garcia-Bustos, J., Wells, T. N. C., Palmer, M. J., Jabbar, A., Gasser, R. B. & Baell, J. B., 11 Apr 2019, In : Journal of Medicinal Chemistry. 62, 7, p. 3367-3380 14 p.Research output: Contribution to journal › Article › Research › peer-review
Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation
Stanley, C. P., Maghzal, G. J., Ayer, A., Talib, J., Giltrap, A. M., Shengule, S., Wolhuter, K., Wang, Y., Chadha, P., Suarna, C., Prysyazhna, O., Scotcher, J., Dunn, L. L., Prado, F. M., Nguyen, N., Odiba, J. O., Baell, J. B., Stasch, J. P., Yamamoto, Y., Di Mascio, P. & 3 others, , 28 Feb 2019, In : Nature. 566, 7745, p. 548-552 5 p.Research output: Contribution to journal › Letter › Research › peer-review
Open Access
File
Structure-Activity Relationship Studies of Tolfenpyrad Reveal Subnanomolar Inhibitors of Haemonchus contortus Development
Le, T. G., Kundu, A., Ghoshal, A., Nguyen, N. H., Preston, S., Jiao, Y., Ruan, B., Xue, L., Huang, F., Keiser, J., Hofmann, A., Chang, B. C. H., Garcia-Bustos, J., Wells, T. N. C., Palmer, M. J., Jabbar, A., Gasser, R. B. & Baell, J. B., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 1036-1053 8 p.Research output: Contribution to journal › Article › Research › peer-review
Prizes
2004 National Biota Prize for Medicinal Chemistry
Jonathan Baell (Recipient), 2005
Prize: Prize (including medals and awards)