Jonathan Baell


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Personal profile



Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences


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Research interests

  • Molecular design
  • Peptidomimetics
  • Small molecule screening libraries and chemoinformatics
  • Hit-to-lead and lead optimisation medicinal chemistry
  • Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
  • Pre-clinical development of new drug candidates

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Projects 2012 2021

Research Output 1998 2019

3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity

Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 othersPrice, R. N., Marfurt, J., Charman, S. A., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Edstein, M. D., Avery, V. M. & Baell, J. B., 1 Jan 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2485-2498 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Contemporary Anti-Ebola Drug Discovery Approaches and Platforms

Schneider-Futschik, E. K., Hoyer, D., Khromykh, A. A., Baell, J. B., Marsh, G. A., Baker, M. A., Li, J. & Velkov, T., 1 Nov 2019, In : ACS Infectious Diseases. 5, 1, p. 35-48 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Novel 1-Methyl-1 H-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic Activity

Le, T. G., Kundu, A., Ghoshal, A., Nguyen, N. H., Preston, S., Jiao, Y., Ruan, B., Xue, L., Huang, F., Keiser, J., Hofmann, A., Chang, B. C. H., Garcia-Bustos, J., Wells, T. N. C., Palmer, M. J., Jabbar, A., Gasser, R. B. & Baell, J. B., 11 Apr 2019, In : Journal of Medicinal Chemistry. 62, 7, p. 3367-3380 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation

Stanley, C. P., Maghzal, G. J., Ayer, A., Talib, J., Giltrap, A. M., Shengule, S., Wolhuter, K., Wang, Y., Chadha, P., Suarna, C., Prysyazhna, O., Scotcher, J., Dunn, L. L., Prado, F. M., Nguyen, N., Odiba, J. O., Baell, J. B., Stasch, J. P., Yamamoto, Y., Di Mascio, P. & 3 othersEaton, P., Payne, R. J. & Stocker, R., 28 Feb 2019, In : Nature. 566, 7745, p. 548-552 5 p.

Research output: Contribution to journalLetterResearchpeer-review

Open Access

Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists

Deora, G. S., Qin, C. X., Vecchio, E. A., Debono, A. J., Priebbenow, D. L., Brady, R. M., Beveridge, J., Teguh, S. C., Deo, M., May, L. T., Krippner, G., Ritchie, R. H. & Baell, J. B., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5242-5248 7 p.

Research output: Contribution to journalArticleResearchpeer-review


2004 National Biota Prize for Medicinal Chemistry

Jonathan Baell (Recipient), 2005

Prize: Prize (including medals and awards)

Adrien Albert Award 2018

Jonathan Baell (Recipient), 2018

Prize: National/international honour