Jonathan Baell

Professor

19992021
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Personal profile

Biography

Position

Larkins Fellow
NHMRC Principal Research Fellow
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences

 

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Research interests

  • Molecular design
  • Peptidomimetics
  • Small molecule screening libraries and chemoinformatics
  • Hit-to-lead and lead optimisation medicinal chemistry
  • Drug discovery in infectious disease (particularly neglected diseases including malaria) and epigenetic modulation associated with cancer
  • Pre-clinical development of new drug candidates

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Projects 2012 2021

Novel Radioligands for PET imaging and phenotyping of multiple sclerosis diagnosis

Baell, J. B., Kilpatrick, T. J., Binder, M. D., Vivash, L. E. & Ackermann, U.

1/01/1831/12/20

Project: Research

Targeted development of AMPK β2-isoform allosteric activators

Oakhill, J., Baell, J. B. & Kemp, B. E.

1/01/1831/12/21

Project: Research

Eliminating Visceral Leishmaniasis - An Australian-Indian Partnership

Baell, J. B., McConville, M. J., Talukdar, A. & Ganguly, D.

23/06/1723/06/20

Project: Research

New drugs against parasitic nematodes of livestock animals

Gasser, R. B., Baell, J. B., Jabbar, A., Hofmann, A., Wells, T., Burrows, J., Waterson, D. & Wilks, A. F.

29/05/1716/06/20

Project: Research

Novel therapeutics targeting neuronal transport pathways in MND

Atkins, J., Baell, J. B., Abbott, B., Laird, A. & Walker, A.

1/04/1731/03/19

Project: Research

Research Output 1999 2018

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D. 6 Feb 2018 In : Chemistry-A European Journal. 24, 8, p. 1922-1930 9 p.

Research output: Contribution to journalArticle

Open Access
File
Open Access
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Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

Jiao, Y., Preston, S., Song, H., Jabbar, A., Liu, Y., Baell, J., Hofmann, A., Hutchinson, D., Wang, T., Koehler, A. V., Fisher, G. M., Andrews, K. T., Laleu, B., Palmer, M. J., Burrows, J. N., Wells, T. N. C., Wang, Q. & Gasser, R. B. 31 May 2017 In : Parasites and Vectors. 10, 1, 272

Research output: Contribution to journalArticle

Open Access
File

Optimization of 2-anilino 4-amino substituted quinazolines into potent antimalarial agents with oral in vivo activity

Gilson, P. R., Tan, C., Jarman, K. E., Lowes, K. N., Curtis, J. M., Nguyen, W., Di Rago, A. E., Bullen, H. E., Prinz, B., Duffy, S., Baell, J. B., Hutton, C. A., Jousset Subroux, H., Crabb, B. S., Avery, V. M., Cowman, A. F. & Sleebs, B. E. 9 Feb 2017 In : Journal of Medicinal Chemistry. 60, 3, p. 1171-1188 18 p.

Research output: Contribution to journalArticle

Prizes

2004 National Biota Prize for Medicinal Chemistry

Jonathan Bayldon Baell (Recipient), 2005

Prize: Prize (including medals and awards)