John Price

Dr

19992017
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Research Output 1999 2017

2017

Melphalan modifies the bone microenvironment by enhancing osteoclast formation

Chai, R. C., McDonald, M. M., Terry, R. L., Kovačić, N., Down, J. M., Mohanty, S. T., Haffari, G., Xu, J., Gillespie, M. T., Rogers, M. J., Price, J. T., Croucher, P. I. & Quinn, J. M. W., 2017, In : Oncotarget. 8, 40, p. 68047-68058 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016

Mammographically dense human breast tissue stimulates MCF10DCIS.com progression to invasive lesions and metastasis

Huo, C. W., Waltham, M., Khoo, C., Fox, S. B., Hill, P., Chen, S., Chew, G. L., Price, J. T., Nguyen, C. H., Williams, E. D., Henderson, M., Thompson, E. W. & Britt, K. L., 25 Oct 2016, In : Breast Cancer Research. 18, 1, 106.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

PtdIns(3,4,5)P3 -dependent rac exchanger 1 (PREX1) rac-guanine nucleotide exchange factor (GEF) activity promotes breast cancer cell proliferation and tumor growth via activation of extracellular signal-regulated kinase 1/2 (ERK1/2) signaling

Liu, H-J., Ooms, L. M., Srijakotre, N., Man, J., Vieusseux, J., Waters, J. E., Feng, Y., Bailey, C. G., Rasko, J. E. J., Price, J. T. & Mitchell, C. A., 12 Aug 2016, In : Journal of Biological Chemistry. 291, 33, p. 17258-17270 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The Helicobacter pylori cytotoxin CagA is essential for suppressing host heat shock protein expression

Lang, B. J., Gorrell, R. J., Tafreshi, M., Hatakeyama, M., Kwok, T. & Price, J. T., May 2016, In : Cell Stress and Chaperones. 21, 3, p. 523-533 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1)

Feeney, S. J., Mcgrath, M. J., Sriratana, A., Gehrig, S. M., Lynch, G. S., D'Arcy, C. E., Price, J. T., McLean, C. A., Tupler, R. & Mitchell, C. A., 19 Feb 2015, In : PLoS ONE. 10, 2, 29 p., e0117665.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The inositol polyphosphate 5-Phosphatase PIPP regulates AKT1-Dependent breast cancer growth and metastasis

Ooms, L. M., Binge, L. C., Davies, E. M., Rahman, P., Conway, J. R. W., Gurung, R., Ferguson, D. T., Papa, A., Fedele, C. G., Vieusseux, J. L., Chai, R. C. C., Koentgen, F., Price, J. T., Tiganis, T., Timpson, P., McLean, C. A. & Mitchell, C. A., 10 Aug 2015, In : Cancer Cell. 28, 2, p. 155-169 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014

Context-dependent role of Grb7 in HER2+ve and triple-negative breast cancer cell lines

Lim, R. C. C., Price, J. T. & Wilce, J. A., 2014, In : Breast Cancer Research and Treatment. 143, 3, p. 593 - 603 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Maspin is not required for embryonic development or tumour suppression

Teoh, S. S. Y., Vieusseux, J. L., Prakash, M. D., Berkowicz, S. R., Luu, J., Bird, C. H., Law, R. H. P., Rosado, C. J., Price, J. T., Whisstock, J. C. & Bird, P. I., 2014, In : Nature Communications. 5, (Art. No.: 3164), p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner

Chai, R. C. C., Kouspou, M. M., Lang, B. J., Nguyen, C. H., van der Kraan, A. G., Vieusseux, J. L., Lim, R. C. C., Gillespie, M. T., Bnejamin, I. J., Quinn, J. M. W. & Price, J. T., 2014, In : Journal of Biological Chemistry. 289, 19, p. 13602 - 13614 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Distinct immunomodulatory and migratory mechanisms underpin the therapeutic potential of human mesenchymal stem cells in autoimmune demyelination

Payne, N. L., Sun, G., McDonald, C., Clayton, D. J., Moussa, L., Emerson-Webber, A. C., Veron, N., Siatskas, C., Herszfeld, D., Price, J. T. & Bernard, C. C. A., 2013, In : Cell Transplantation: the regenerative medicine journal. 22, 8, p. 1409 - 1425 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Heat-shock factor 1 both positively and negatively affects cellular clonogenic growth depending on p53 status

Nguyen, C. H., Lang, B. J., Chai, R. C. C., Vieusseux, J. L., Kouspou, M. M. & Price, J. T., 2013, In : Biochemical Journal. 452, 2, p. 321 - 329 9 p.

Research output: Contribution to journalArticleResearchpeer-review

HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors

van der Kraan, A. G., Chai, R. C. C., Singh, P., Lang, B. J., Wu, J., Gillespie, M. T., Price, J. T. & Quinn, J. M. W., 2013, In : Biochemical Journal. 451, 2, p. 235 - 244 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents

Ambaye, N. D., Gunzburg, M. J., Lim, R. C. C., Price, J. T., Wilce, M. C. J. & Wilce, J. A., 2013, In : ChemMedChem. 8, 2, p. 280 - 288 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

A doxycycline-inducible, tissue-specific aromatase-expressing transgenic mouse

Chow, J., Price, J., Bills, M., Simpson, E. & Boon, W. C., 2012, In : Transgenic Research. 21, 2, p. 415 - 428 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Heat stress induces epithelial plasticity and cell migration independent of heat shock factor 1

Lang, B. J., Nguyen, L., Nguyen, C. H., Vieusseux, J. L., Chai, R. CC., Christophi, C., Fifis, T., Kouspou, M. M. & Price, J. T., 2012, In : Cell Stress and Chaperones. 17, 6, p. 765 - 778 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Analysis of cellular migration using a two-chamber methodology

Kouspou, M. & Price, J., 2011, Molecular Chaperones: Methods and Protocols. Calderwood, S. K. & Prince, T. L. (eds.). 1st ed. USA: Humana Press, p. 303 - 317 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Benzopyrazine derivatives: a novel class of Growth Factor receptor bound protein 7 antagonists

Ambaye, N. D., Gunzburg, M. J., Lim, R. CC., Price, J. T., Wilce, M. CJ. & Wilce, J. A., 2011, In : Bioorganic & Medicinal Chemistry. 19, p. 693 - 701 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Uptake of a cell permeable G7-18NATE construct into cells and binding with the Grb7-SH2 domain

Ambaye, N. D., Lim, R. C. C., Clayton, D. J., Gunzburg, M. J., Price, J. T., Pero, S. C., Krag, D. N., Wilce, M. C. J., Aguilar, M. I., Perlmutter, P. & Wilce, J. A., 2011, In : Journal of Peptide Science. 96, 2, p. 181 - 188 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Influenza A virus facilitates Streptococcus pneumoniae transmission and disease

Diavatopoulos, D. A., Short, K. R., Price, J. T., Wilksch, J. J., Brown, L. E., Briles, D. E., Strugnell, R. A. & Wijburg, O. LC., 2010, In : FASEB Journal. 24, 6, p. 1789 - 1798 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

Fedele, C. G., Ooms, L. M., Ho, M., Vieusseux, J. L., O'Toole, S. A., Millar, E. K., Lopez-Knowles, E., Sriratana, A., Gurung, R., Baglietto, L., Giles, G., Bailey, C. G., Rasko, J. EJ., Shields, B. J., Price, J. T., Majerus, P. W., Sutherland, R. L., Tiganis, T., McLean, C. A. & Mitchell, C. A., 2010, In : Proceedings of the National Academy of Sciences. 107, 51, p. 22231 - 22236 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Osteoclast inhibitory lectin (OCIL) inhibits osteoblast differentiation and function in vitro

Nakamura, A., Ly, C., Cipetic, M., Sims, N. A., Vieusseux, J., Kartsogiannis, V., Bouralexis, S., Saleh, H., Zhou, H., Price, J. T., Martin, T. J., Ng, K. W., Gillespie, M. T. & Quinn, J. M. W., 2007, In : Bone. 40, 2, p. 305 - 315 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells

Borrirukwanit, K., Lafleur, M. A., Mercuri, F. A., Blick, T., Price, J. T., Fridman, R., Pereira, J. J., Leardkamonkarn, V. & Thompson, E. W., 2007, In : Matrix Biology. 26, 4, p. 291 - 305 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Hsp90 increases LIM kinase activity by promoting its homo-dimerization.

Li, R., Soosairajah, J., Harari, D., Citri, A., Price, J. T., Ng, H. L., Morton, C. J., Parker, M. W., Yarden, Y. & Bernard, O., 2006, In : FASEB Journal. 20, 8, p. 1218 - 1220 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Myoepithelial molecular markers in human breast carcinoma PMC42-LA cells are induced by extracellular matrix and stromal cells

Lebret, S. C., Newgreen, D. F., Waltham, M. C., Price, J. T., Thompson, E. W. & Ackland, M. L., 2006, In : In Vitro Cellular and Developmental Biology - Animal. 42, 10, p. 298 - 307 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

The heat shock protein 90 inhibitor, 17-allylamino-17- demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line

Price, J. T., Quinn, J. M. W., Sims, N. A., Vieusseux, J. L., Waldeck, K., Docherty, S. E., Myers, D., Nakamura, A., Waltham, M., Gillespie, M. T. & Thompson, E. W., 2005, In : Cancer Research. 65, 11, p. 4929 - 4938 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Bimolecular interaction of Insulin-Like Growth Factor (IGF) binding Protein-2 with 3 negatively modulates IGF-I-Mediated migration and tumor growth

Pereira, J. J., Meyer, T., Docherty, S. E., Reid, H. H., Marshall, J., Thompson, E. W., Rossjohn, J. & Price, J. T., 2004, In : Cancer Research. 64, 3, p. 977 - 984 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Bimolecular Interaction of Insulin-Like Growth Factor (IGF) Binding Protein-2 with αvβ3 Negatively Modulates IGF-I-Mediated Migration and Tumor Growth

Pereira, J. J., Meyer, T., Docherty, S. E., Reid, H. H., Marshall, J., Thompson, E. W., Rossjohn, J. & Price, J. T., 1 Feb 2004, In : Cancer Research. 64, 3, p. 977-984 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2003

A role for V integrin subunit in TGF--stimulated osteoclastogenesis

Chin, S. L., Johnson, S. A., Quinn, J. M. W., Mirosavljevic, D., Price, J. T., Dudley, A. C. & Thomas, D. M., 2003, In : Biochemical and Biophysical Research Communications. 307, 4, p. 1051 - 1058 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Epidermal growth factor-induced epithelio-mesenchymal transition in human breast carcinoma cells

Ackland, M. L., Newgreen, D. F., Fridman, M., Waltham, M. C., Arvanitis, A., Minichiello, J., Price, J. T. & Thompson, E. W., 2003, In : Laboratory Investigation. 83, 3, p. 435 - 448 14 p.

Research output: Contribution to journalArticleResearchpeer-review

STI-571 inhibits in vitro angiogenesis

Dudley, A. C., Gilbert, R. E., Thomas, D. M., Cox, A. J., Price, J. T., Best, J. D. & Jenkins, A. J., 2003, In : Biochemical and Biophysical Research Communications. 310, 1, p. 135 - 142 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2002

Doxycycline-inducible expression of SPARC/ Osteonectin/BM40 in MDA-MB-231 human breast cancer cells results in growth inhibition

Dhanesuan, N., Price, J. T., Sharp, J. A., Blick, T. & Thompson, E. W., 2002, In : Breast Cancer Research and Treatment. 75, 1, p. 73 - 85 13 p.

Research output: Contribution to journalArticleResearchpeer-review

MT1-MMP-Dependent and -Independent Regulation of Gelatinase A Activation in Long-Term, Ascorbate-Treated Fibroblast Cultures: Regulation by Fibrillar Collagen

Ruangpanit, N., Price, J. T., Holmbeck, K., Birkedal-Hansen, H., Guenzler, V., Huang, X., Chan, D., Bateman, J. F. & Thompson, E. W., 2002, In : Experimental Cell Research. 272, 2, p. 109 - 118 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2001

Identification and characterisation of a platelet GPIb/V/IX-like complex on human breast cancers: implications for the metastatic process

Suter, C. M., Hogg, P. J., Price, J. T., Chong, B. H. & Ward, R. L., 2001, In : Japanese Journal of Cancer Research. 92, 10, p. 1082 - 1092 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

Epidermal growth factor promotes MDA-MB-231 breast cancer cell migration through a phosphatidylinositol 3'-kinase and phospholipase C-dependent mechanism

Price, J. T., Tiganis, T., Agarwal, A., Djakiew, D. & Thompson, E. W., 1 Nov 1999, In : Cancer Research. 59, 21, p. 5475-5478 4 p.

Research output: Contribution to journalArticleResearchpeer-review