Projects per year
Personal profile
Biography
John-Paul Nicolo, MBBS (Hons), BMedSci, FRACP, is a consultant neurologist and epileptologist. He is currently acting head of the epilepsy program at Royal Melbourne Hospital, and also has clinical appointments at the Alfred Hospital and University Hospital Geelong.
Through his PhD he has pioneered the use of 7-tesla MRI to identify novel imaging biomarkers of post-stroke epilepsy, and has designed and led the PEPSTEP trial of perampanel for prevention of post-stroke epilepsy. He completed his neurology training and an epilepsy fellowship across RMH and the Alfred Hospital.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Epilepsy
- Novel imaging biomarkers
- Post-stroke epilepsy
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Randomized, Double-blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Kwan, P. (Primary Chief Investigator (PCI)), Perucca, P. (Partner Investigator (PI)), Nicolo, J.-P. (Partner Investigator (PI)), D'Souza, W. J. (Partner Investigator (PI)) & Reutens, D. (Partner Investigator (PI))
24/06/23 → 25/06/25
Project: Research
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A multi-modality med-tech approach to dietary therapy for epilepsy care (MED-TEC): A randomised controlled trial
Kaul, N. (Primary Chief Investigator (PCI)), Kwan, P. (Chief Investigator (CI)), Ademi Delaney, Z. (Chief Investigator (CI)), Chen, Z. (Chief Investigator (CI)), Johns, H. (Chief Investigator (CI)), Nicolo, J.-P. (Chief Investigator (CI)), Vivash, L. (Chief Investigator (CI)), Skafidas, E. S. (Chief Investigator (CI)) & Erlichster, M. (Chief Investigator (CI))
1/06/23 → 31/05/27
Project: Research
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PERSONAL: Personalised Selection of Medication for Newly Diagnosed Adult Epilepsy – the PERSONAL Trial
Kwan, P. (Primary Chief Investigator (PCI)), Chen, Z. (Chief Investigator (CI)), Lannin, N. (Chief Investigator (CI)), Ademi Delaney, Z. (Chief Investigator (CI)), Ge, Z. (Chief Investigator (CI)), Reutens, D. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), D'Souza, W. J. (Chief Investigator (CI)), Perucca, P. (Chief Investigator (CI)), Reeder, S. (Chief Investigator (CI)), Nikpour, A. (Associate Investigator (AI)), Wong, C. (Associate Investigator (AI)), Kiley, M. (Associate Investigator (AI)), Saw, J.-L. (Associate Investigator (AI)), Nicolo, J.-P. (Associate Investigator (AI)), Seneviratne, U. (Associate Investigator (AI)), Carney, P. (Associate Investigator (AI)), Jones, D. (Associate Investigator (AI)), Somerville, E. R. (Associate Investigator (AI)) & Stapleton, C. (Associate Investigator (AI))
1/02/23 → 31/01/27
Project: Research
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Machine learning models for personalised epilepsy management
Kwan, P. (Primary Chief Investigator (PCI)), Chen, Z. (Chief Investigator (CI)), Zhang, D. (Chief Investigator (CI)), Foster, E. (Chief Investigator (CI)), Haffari, R. (Chief Investigator (CI)), Vaughan, D. N. (Associate Investigator (AI)), Lawn, N. D. (Associate Investigator (AI)), Perucca, P. (Associate Investigator (AI)), Nicolo, J.-P. (Associate Investigator (AI)), Carney, P. (Associate Investigator (AI)), Brodie, M. (Associate Investigator (AI)), Ge, Z. (Associate Investigator (AI)), Anderson, A. (Associate Investigator (AI)) & Zhang, D. (Associate Investigator (AI))
1/01/22 → 31/12/24
Project: Research
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Brain glutamate imaging by ultra-high-field MRI for prediction of post-stroke epilepsy
Kwan, P. (Primary Chief Investigator (PCI)), O'Brien, T. (Chief Investigator (CI)), Cloud, G. (Chief Investigator (CI)), Hand, P. (Chief Investigator (CI)), Yan, B. (Chief Investigator (CI)), Nicolo, J.-P. (Chief Investigator (CI)) & Wright, D. (Chief Investigator (CI))
11/03/19 → 8/03/21
Project: Research
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Personalised selection of medication for newly diagnosed adult epilepsy: Study protocol of a first-in-class, double-blind, randomised controlled trial
Thom, D., Chang, R. S. K., Lannin, N. A., Ademi, Z., Ge, Z., Reutens, D., O'Brien, T., D'Souza, W., Perucca, P., Reeder, S., Nikpour, A., Wong, C., Kiley, M., Saw, J. L., Nicolo, J. P., Seneviratne, U., Carney, P., Jones, D., Somerville, E. & Stapleton, C. & 9 others, , Apr 2025, In: BMJ Open. 15, 4, 8 p., e086607.Research output: Contribution to journal › Article › Other › peer-review
Open Access -
Applying the ILAE diagnostic criteria for Lennox-Gastaut syndrome in the real-world setting: A multicenter retrospective cohort study
Nightscales, R., Chen, Z., Barnard, S., Auvrez, C., Tao, G., Sivathamboo, S., Bennett, C., Rychkova, M., D'Souza, W., Berkovic, S. F., Nicolo, J. P., O'Brien, T. J., Perucca, P., Scheffer, I. E. & Kwan, P., Apr 2024, In: Epilepsia Open. 9, 2, p. 602-612 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Association of Localizing 18F-FDG-PET Hypometabolism and Outcome Following Epilepsy Surgery: Systematic Review and Meta-Analysis
Courtney, M. R., Antonic-Baker, A., Chen, Z., Sinclair, B., Nicolo, J. P., Neal, A., Marotta, C., Bunyamin, J., Law, M., Kwan, P., O'Brien, T. J. & Vivash, L. (Leading Author), 14 May 2024, In: Neurology. 102, 9, 14 p., e209304.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Automated segmentation of epilepsy surgical resection cavities: Comparison of four methods to manual segmentation
Courtney, M. R., Sinclair, B., Neal, A., Nicolo, J. P., Kwan, P., Law, M., O'Brien, T. J. & Vivash, L. (Leading Author), 1 Aug 2024, In: NeuroImage. 296, 8 p., 120682.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Role of the glymphatic system and perivascular spaces as a potential biomarker for post-stroke epilepsy
Hlauschek, G., Nicolo, J. P., Sinclair, B., Law, M., Yasuda, C. L., Cendes, F., Lossius, M. I., Kwan, P. & Vivash, L. (Leading Author), Feb 2024, In: Epilepsia Open. 9, 1, p. 60-76 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access9 Citations (Scopus)